Publications by authors named "Giovanna Peruzzi"

51Publications

Tumor-on-a-chip platforms to study cancer-immune system crosstalk in the era of immunotherapy.

Lab Chip 2020 Dec 14. Epub 2020 Dec 14.

Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.

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December 2020

Assessing Phosphorylation of STAT Transcription Factors in Mouse Innate Lymphoid Cells.

Methods Mol Biol 2020 ;2121:59-70

Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.

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January 2020

A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression.

Biochim Biophys Acta Biomembr 2020 03 16;1862(3):183159. Epub 2019 Dec 16.

Department of Molecular Medicine, "Sapienza" University of Rome, viale Regina Elena 291, 00161 Rome, Italy. Electronic address:

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March 2020

Reversible Cavitation-Induced Junctional Opening in an Artificial Endothelial Layer.

Small 2019 12 25;15(51):e1905375. Epub 2019 Nov 25.

Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Via Eudossiana 18, 00184, Rome, Italy.

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December 2019

Fractalkine Modulates Microglia Metabolism in Brain Ischemia.

Front Cell Neurosci 2019 13;13:414. Epub 2019 Sep 13.

Department of Physiology and Pharmacology, Laboratory Affiliated to Istituto Pasteur Italia - Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.

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September 2019

Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.

Cell Rep 2019 06;27(13):3818-3831.e5

Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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June 2019

Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.

Nat Commun 2019 03 8;10(1):1121. Epub 2019 Mar 8.

Department of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.

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March 2019

Counter-regulation of regulatory T cells by autoreactive CD8 T cells in rheumatoid arthritis.

J Autoimmun 2019 05 16;99:81-97. Epub 2019 Feb 16.

Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, 00161, Rome, Italy; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy; Istituto Pasteur - Fondazione Cenci Bolognetti, 00185, Rome, Italy. Electronic address:

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May 2019

Perspectives on cavitation enhanced endothelial layer permeability.

Colloids Surf B Biointerfaces 2018 Aug 16;168:83-93. Epub 2018 Feb 16.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy; Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Italy.

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August 2018

Characterization of the lncRNA transcriptome in mESC-derived motor neurons: Implications for FUS-ALS.

Stem Cell Res 2018 03 31;27:172-179. Epub 2018 Jan 31.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy; Department of Biology and Biotechnology, Sapienza University of Rome, Italy; Institute of Molecular Biology and Pathology of CNR, Rome, Italy; Institute Pasteur Fondazione Cenci-Bolognetti, Sapienza University of Rome, Italy. Electronic address:

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March 2018

A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.

Mol Neurobiol 2018 Oct 12;55(10):7635-7651. Epub 2018 Feb 12.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.

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October 2018

FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis.

Stem Cell Reports 2017 11 5;9(5):1450-1462. Epub 2017 Oct 5.

Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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November 2017

Natural killer cell activity and dysfunction in Hermansky-Pudlak syndrome.

Br J Haematol 2017 Jan 21;176(1):118-123. Epub 2016 Oct 21.

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.

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January 2017

Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.

Sci Signal 2015 Oct 27;8(400):ra108. Epub 2015 Oct 27.

Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy. Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" University of Rome, 00161 Rome, Italy.

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October 2015

Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells.

J Allergy Clin Immunol 2016 Apr 21;137(4):1165-1177. Epub 2015 Oct 21.

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md. Electronic address:

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April 2016

Defective microglial development in the hippocampus of Cx3cr1 deficient mice.

Front Cell Neurosci 2015 31;9:111. Epub 2015 Mar 31.

Department of Physiology and Pharmacology, Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome Italy ; Istituto di Ricovero e Cura a Carattere Scientifico Neuromed Pozzilli, Italy.

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April 2015

Effect of surgery on pancreatic tumor-dependent lymphocyte asset: modulation of natural killer cell frequency and cytotoxic function.

Pancreas 2015 Apr;44(3):386-93

From the *Section of Interdisciplinary Surgery F. Durante, Department of Surgical Sciences, †Department of Molecular Medicine, ‡Istituto Italiano di Tecnologia, CLNS, and §Department of Experimental Medicine, Sapienza University of Rome, Italy.

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April 2015

Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells.

J Immunol 2013 Aug 12;191(4):1883-94. Epub 2013 Jul 12.

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

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August 2013

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity.

Blood 2013 Jun 30;121(23):4672-83. Epub 2013 Apr 30.

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

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June 2013

Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin.

PLoS One 2010 May 13;5(5):e10636. Epub 2010 May 13.

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America.

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May 2010

Endocytosis and intracellular trafficking of human natural killer cell receptors.

Traffic 2009 Dec 5;10(12):1735-44. Epub 2009 Aug 5.

The Jaffe Food Allergy Institute, Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA.

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December 2009

Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors.

PLoS One 2009 19;4(5):e5604. Epub 2009 May 19.

Department of Experimental Medicine, Institute Pasteur-Fondazione Cenci Bolognetti, Sapienza University, Rome, Italy.

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August 2009

A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens.

J Immunol 2009 May;182(9):5446-52

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

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May 2009

Endocytosis as a mechanism of regulating natural killer cell function: unique endocytic and trafficking pathway for CD94/NKG2A.

Immunol Res 2009 ;43(1-3):210-22

Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Twinbrook II, Room 205, MS 8180 12441 Parklawn Drive, Rockville, MD 20852, USA.

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June 2009

Negative signals from FcepsilonRI engagement attenuate mast cell functions.

Arch Immunol Ther Exp (Warsz) 2007 Jul-Aug;55(4):219-29. Epub 2007 Jul 23.

Department of Experimental Medicine, University "La Sapienza", Viale Regina Elena 324, 00161, Rome, Italy.

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October 2007