Publications by authors named "Giorgio Sirugo"

61Publications

CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa).

Infect Genet Evol 2020 Nov 22;85:104560. Epub 2020 Sep 22.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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November 2020

Interferon-gamma polymorphisms and risk of iron deficiency and anaemia in Gambian children.

Wellcome Open Res 2020 2;5:40. Epub 2020 Jun 2.

Kenya Medical Research Institute (KEMRI) Centre for Geographic Medicine Coast, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.

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June 2020

Evaluating the strength of genetic results: Risks and responsibilities.

PLoS Genet 2019 10 11;15(10):e1008437. Epub 2019 Oct 11.

Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America.

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October 2019

The Plight of Muntaser Ibrahim.

PLoS Genet 2019 03 25;15(3):e1008100. Epub 2019 Mar 25.

Department of Biology and the Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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March 2019

The Missing Diversity in Human Genetic Studies.

Cell 2019 03;177(1):26-31

Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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March 2019

Genomics of human pulmonary tuberculosis: from genes to pathways.

Curr Genet Med Rep 2017 Dec 12;5(4):149-166. Epub 2017 Oct 12.

Department of Population and Quantitative Health Sciences, Cleveland, OH.

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December 2017

Artificial Intelligence and Amikacin Exposures Predictive of Outcomes in Multidrug-Resistant Tuberculosis Patients.

Antimicrob Agents Chemother 2016 10 23;60(10):5928-32. Epub 2016 Sep 23.

Center for Infectious Diseases Research & Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, Texas, USA Department of Medicine, University of Cape Town, Observatory, Cape Town, South Africa

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October 2016

Amikacin Concentrations Predictive of Ototoxicity in Multidrug-Resistant Tuberculosis Patients.

Antimicrob Agents Chemother 2015 Oct 27;59(10):6337-43. Epub 2015 Jul 27.

Office of Global Health, University of Texas Southwestern Medical Center, Dallas, Texas, USA Department of Medicine, University of Cape Town, Observatory, South Africa

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October 2015

Successful MDR-TB treatment regimens including amikacin are associated with high rates of hearing loss.

BMC Infect Dis 2014 Oct 9;14:542. Epub 2014 Oct 9.

Division of Infectious Diseases, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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October 2014

G6PD A- deficiency and severe malaria in The Gambia: heterozygote advantage and possible homozygote disadvantage.

Am J Trop Med Hyg 2014 May 10;90(5):856-9. Epub 2014 Mar 10.

Centro di Ricerca, Ospedale San Pietro Fatebenefratelli, Rome, Italy; Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Genetics, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland; Medical Research Council Laboratories, Fajara, Banjul, The Gambia.

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May 2014

Putting pleiotropy and selection into context defines a new paradigm for interpreting genetic data.

Circ Cardiovasc Genet 2013 Jun 24;6(3):299-307. Epub 2013 Apr 24.

Division of Cardiovascular Medicine, Section of Cardiovascular Disease Prevention, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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June 2013

Multifactor dimensionality reduction reveals a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis.

BioData Min 2013 Feb 18;6(1). Epub 2013 Feb 18.

Institute for Quantitative Biomedical Sciences, Dartmouth College, Hanover NH 03755, USA.

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February 2013

An information-gain approach to detecting three-way epistatic interactions in genetic association studies.

J Am Med Inform Assoc 2013 Jul-Aug;20(4):630-6. Epub 2013 Feb 8.

Computational Genetics Laboratory, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.

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September 2013

Nest-like features in bladder, simulating the nested variant of urothelial carcinoma.

Int J Surg Pathol 2011 Feb 24;19(1):11-9. Epub 2009 Dec 24.

Dipartimento Anatomia Patologica, Azienda Ospedaliera di Melegnano, Milano, Italy.

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February 2011

Common polymorphic variation in the genetically diverse African insulin gene and its association with size at birth.

Hum Genet 2009 Sep 12;126(3):375-84. Epub 2009 May 12.

Department of Paediatrics, Box 116, Addenbrooke's Hospital, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, UK.

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September 2009

FTO gene variation and measures of body mass in an African population.

BMC Med Genet 2009 Mar 5;10:21. Epub 2009 Mar 5.

MRC International Nutrition Group, NPHIRU, EPH, London School of Hygiene & Tropical Medicine, London, UK.

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March 2009

Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis.

Am J Respir Crit Care Med 2008 Jul 17;178(2):203-7. Epub 2008 Apr 17.

Wellcome Trust Centre for Human Genetics, University of Oxford, Churchill Hospital, Headington, Oxford, United Kingdom.

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July 2008

Haptoglobin genotype, anaemia and malaria in Gambian children.

Trop Med Int Health 2008 Jan;13(1):76-82

MRC International Nutrition Group, London School of Hygiene and Tropical Medicine, UK.

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January 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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November 2007