Giorgio Scita

Giorgio Scita

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Giorgio Scita

Publications by authors named "Giorgio Scita"

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Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8.

Cell Rep 2019 Nov;29(9):2546-2555.e4

IFOM-inStem Joint Research Laboratory, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, Karnataka 560065, India. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.090DOI Listing
November 2019

Is cell migration a selectable trait in the natural evolution of cancer development?

Philos Trans R Soc Lond B Biol Sci 2019 08 1;374(1779):20180224. Epub 2019 Jul 1.

IFOM, FIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1098/rstb.2018.0224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627024PMC
August 2019

Mechano-biological model of glioblastoma cells in response to osmotic stress.

Math Biosci Eng 2019 04;16(4):2795-2810

MOX Laboratory, Department of Mathematics, Politecnico di Milano, Italy.

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http://dx.doi.org/10.3934/mbe.2019139DOI Listing
April 2019

The 'endocytic matrix reloaded' and its impact on the plasticity of migratory strategies.

Curr Opin Cell Biol 2018 10 12;54:9-17. Epub 2018 Mar 12.

IFOM, The FIRC Institute of Molecular Oncology, via Adamello 16, 20139 Milan, Italy; University of Milan, School of Medicine, Department of Oncology and Hemato-Oncology-DIPO, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2018.02.006DOI Listing
October 2018

Frustration-induced phases in migrating cell clusters.

Sci Adv 2018 09 12;4(9):eaar8483. Epub 2018 Sep 12.

Department of Physics, University of California, Merced, Merced, CA 95343, USA.

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http://dx.doi.org/10.1126/sciadv.aar8483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135545PMC
September 2018

Harnessing membrane trafficking to promote cancer spreading and invasion: The case of RAB2A.

Small GTPases 2018 07 27;9(4):304-309. Epub 2017 Jan 27.

a IFOM, the FIRC Institute of Molecular Oncology , Milan , Italy.

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http://dx.doi.org/10.1080/21541248.2016.1223990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997154PMC
July 2018

Flocking transitions in confluent tissues.

Soft Matter 2018 May;14(18):3471-3477

Università degli Studi di Milano, Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, 20090 Segrate, Italy.

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http://dx.doi.org/10.1039/c8sm00126jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995478PMC
May 2018

Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity.

Cell 2018 05 26;173(5):1150-1164.e14. Epub 2018 Apr 26.

Humanitas Clinical and Research Center, Via Manzoni 56, 20089 Rozzano, Milan, Italy; Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.081DOI Listing
May 2018

From jamming to collective cell migration through a boundary induced transition.

Soft Matter 2018 May;14(19):3774-3782

Institut für Theoretische Physik, Leopold-Franzens-Universität Innsbruck, Technikerstrasse 21a, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1039/c8sm00128fDOI Listing
May 2018

Modulation of RAB5A early endosome trafficking in response to KRas mediated macropinocytic fluxes in pancreatic cancer cells.

Biochem Biophys Res Commun 2017 11 1;493(1):528-533. Epub 2017 Sep 1.

Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.08.157DOI Listing
November 2017

Rab2 promotes autophagic and endocytic lysosomal degradation.

J Cell Biol 2017 07 8;216(7):1937-1947. Epub 2017 May 8.

Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest H-1117, Hungary

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http://www.jcb.org/lookup/doi/10.1083/jcb.201611027
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http://dx.doi.org/10.1083/jcb.201611027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496615PMC
July 2017

SOS1, ARHGEF1, and DOCK2 rho-GEFs Mediate JAK-Dependent LFA-1 Activation by Chemokines.

J Immunol 2017 01 16;198(2):708-717. Epub 2016 Dec 16.

Department of Medicine, University of Verona, Verona 37134, Italy;

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http://dx.doi.org/10.4049/jimmunol.1600933DOI Listing
January 2017

Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes.

Sci Rep 2016 12 23;6:39632. Epub 2016 Dec 23.

Unité Trafic Membranaire et Pathogenèse, Institut Pasteur, 25-28 Rue du Docteur Roux, 75724 Paris CEDEX 15, France.

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http://dx.doi.org/10.1038/srep39632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180355PMC
December 2016

Direct interaction between exocyst and Wave complexes promotes cell protrusions and motility.

J Cell Sci 2016 10 2;129(20):3756-3769. Epub 2016 Sep 2.

Institut Curie, Centre de Recherche, Paris Sciences et Lettres Research University, Paris 75005, France ART group, Inserm U830, Paris 75005, France

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http://dx.doi.org/10.1242/jcs.187336DOI Listing
October 2016

Time to tackle the incumbency advantage in science: A survey of scientists shows strong support for funding policies that would distribute funds more evenly among laboratories and thereby benefit new and smaller research groups.

EMBO Rep 2016 09 4;17(9):1254-6. Epub 2016 Aug 4.

Institute FIRC of Molecular Oncology & Department of Oncology and HematoOncology, IFOM Foundation, University of Milan, Milan, Italy.

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http://dx.doi.org/10.15252/embr.201642998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007573PMC
September 2016

RABGTPases in MT1-MMP trafficking and cell invasion: Physiology versus pathology.

Small GTPases 2015 24;6(3):145-52. Epub 2015 Jun 24.

a Institute for Medical Microbiology; Virology and Hygiene ; University Medical Center Eppendorf ; Hamburg , Germany.

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http://dx.doi.org/10.4161/21541248.2014.985484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601268PMC
June 2016

The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling.

J Cell Biol 2015 Dec 14;211(6):1177-92. Epub 2015 Dec 14.

FIRC Institute of Molecular Oncology, 20139 Milan, Italy Dipartimento di Bioscienze, Università degli Studi di Milano, 20122 Milan, Italy Department of Immunology, Genetics and Pathology, Uppsala University, 751 05 Uppsala, Sweden

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http://dx.doi.org/10.1083/jcb.201501089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687874PMC
December 2015

L-Proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation.

Stem Cell Reports 2013 10;1(4):307-21. Epub 2013 Oct 10.

Stem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati-Traverso," CNR, 80131 Naples, Italy ; Institute of Genetics and Biophysics "A. Buzzati-Traverso," CNR, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.stemcr.2013.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849245PMC
October 2015

Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries.

Front Oncol 2015 26;5:45. Epub 2015 Feb 26.

Fondazione Istituto FIRC di Oncologia Molecolare (IFOM) , Milan , Italy ; Dipartimento di Scienze della Salute, Università degli Studi di Milano , Milan , Italy.

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http://dx.doi.org/10.3389/fonc.2015.00045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341543PMC
March 2015

Nuclear and cellular plasticity: nuclear RAC1 takes center stage.

Dev Cell 2015 Feb;32(3):261-3

IFOM (FIRC Institute for Molecular Oncology), 20139 Milan, Italy; Dipartimento di Science della Salute, Università degli Studi di Milano, 20142 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.01.015DOI Listing
February 2015

Collective cell motility promotes chemotactic prowess and resistance to chemorepulsion.

Curr Biol 2015 Jan 8;25(2):242-250. Epub 2015 Jan 8.

INSERM, UMR1043, Toulouse 31024, France; CNRS, UMR5282, Toulouse 31024, France; Université Toulouse III Paul Sabatier, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse 31024, France. Electronic address:

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http://www.cell.com/current-biology/pdf/S0960-9822(14)01491-
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http://linkinghub.elsevier.com/retrieve/pii/S096098221401491
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http://dx.doi.org/10.1016/j.cub.2014.11.030DOI Listing
January 2015

The CDC42-interacting protein 4 controls epithelial cell cohesion and tumor dissemination.

Dev Cell 2014 Sep;30(5):553-68

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy; Dipartimento di Scienze della Salute, San Paolo, Università degli Studi di Milano, 20122 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.08.006DOI Listing
September 2014

ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.

Cell 2014 Jul;158(3):633-46

Fondazione Istituto FIRC di Oncologia Molecolare (IFOM), Via Adamello 16, 20139 Milan, Italy; Università degli Studi di Milano, 20122 Milan, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140080
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http://dx.doi.org/10.1016/j.cell.2014.05.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121522PMC
July 2014

Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.

Nat Struct Mol Biol 2014 Apr 2;21(4):413-22. Epub 2014 Mar 2.

Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/nsmb.2781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091835PMC
April 2014

The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration.

Curr Biol 2013 Dec 14;23(23):2355-64. Epub 2013 Nov 14.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milano, Italy.

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http://dx.doi.org/10.1016/j.cub.2013.09.060DOI Listing
December 2013

Membrane and actin dynamics interplay at lamellipodia leading edge.

Curr Opin Cell Biol 2013 Oct 29;25(5):565-73. Epub 2013 Apr 29.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1016/j.ceb.2013.04.001DOI Listing
October 2013

LIN7-IRSp53: A novel pathway for filopodia and neurite formation?

Commun Integr Biol 2012 Nov;5(6):631-3

Department of BIOMETRA; Università degli Studi di Milano; CNR-Institute of Neuroscience; Milan, Italy.

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https://air.unimi.it/retrieve/handle/2434/223958/285234/cib-
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http://www.tandfonline.com/doi/abs/10.4161/cib.21686
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http://dx.doi.org/10.4161/cib.21686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541334PMC
November 2012

LIN7 regulates the filopodium- and neurite-promoting activity of IRSp53.

J Cell Sci 2012 Oct 5;125(Pt 19):4543-54. Epub 2012 Jul 5.

Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan 20129, Italy.

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http://dx.doi.org/10.1242/jcs.106484DOI Listing
October 2012

From filopodia to synapses: the role of actin-capping and anti-capping proteins.

Eur J Neurosci 2011 Nov;34(10):1655-62

Department of Medical Pharmacology and CNR Institute of Neuroscience, University of Milan, Milano, Italy.

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http://dx.doi.org/10.1111/j.1460-9568.2011.07897.xDOI Listing
November 2011

The signaling adaptor Eps8 is an essential actin capping protein for dendritic cell migration.

Immunity 2011 Sep 11;35(3):388-99. Epub 2011 Aug 11.

IFOM, FIRC Institute of Molecular Oncology Foundation at IFOM-IEO Campus, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1016/j.immuni.2011.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424277PMC
September 2011

Secretory and endo/exocytic trafficking in invadopodia formation: the MT1-MMP paradigm.

Eur J Cell Biol 2011 Feb-Mar;90(2-3):108-14

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1016/j.ejcb.2010.04.007DOI Listing
July 2011

Propagating cell-membrane waves driven by curved activators of actin polymerization.

PLoS One 2011 Apr 21;6(4):e18635. Epub 2011 Apr 21.

Department of Chemical Physics, the Weizmann Institute of Science, Rehovot, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018635PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080874PMC
April 2011

The catalytic class I(A) PI3K isoforms play divergent roles in breast cancer cell migration.

Cell Signal 2011 Mar 5;23(3):529-41. Epub 2010 Nov 5.

Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.cellsig.2010.10.021DOI Listing
March 2011

Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8.

Curr Biol 2011 Jan 13;21(2):167-72. Epub 2011 Jan 13.

Laboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.cell.com/cms/attachment/2021742303/2041572552/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S096098221001714
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http://dx.doi.org/10.1016/j.cub.2010.12.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040242PMC
January 2011

Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells.

Exp Cell Res 2010 Jul 23;316(12):1914-24. Epub 2010 Feb 23.

Department of General, Visceral and Transplant Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.yexcr.2010.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304094PMC
July 2010

The endocytic matrix.

Nature 2010 Jan;463(7280):464-73

IFOM, the FIRC Institute for Molecular Oncology Foundation, at the IFOM-IEO Campus, Via Adamello 16, 20139, Milan, Italy.

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http://dx.doi.org/10.1038/nature08910DOI Listing
January 2010

F-BAR-containing adaptor CIP4 localizes to early endosomes and regulates Epidermal Growth Factor Receptor trafficking and downregulation.

Cell Signal 2009 Nov 24;21(11):1686-97. Epub 2009 Jul 24.

Queen's University Cancer Research Institute, Division of Cancer Biology & Genetics and Department of Biochemistry, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cellsig.2009.07.007DOI Listing
November 2009

Induction of HoxB transcription by retinoic acid requires actin polymerization.

Mol Biol Cell 2009 Aug 28;20(15):3543-51. Epub 2009 May 28.

San Raffaele Scientific Institute and University Vita Salute San Raffaele, 20132 Milan, Italy.

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http://dx.doi.org/10.1091/mbc.e09-02-0114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719572PMC
August 2009

Endocytosis and spatial restriction of cell signaling.

Mol Oncol 2009 Aug 6;3(4):280-96. Epub 2009 Jun 6.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 20139 Milan, Italy.

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http://dx.doi.org/10.1016/j.molonc.2009.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527950PMC
August 2009

Coordination of membrane and actin cytoskeleton dynamics during filopodia protrusion.

PLoS One 2009 May 25;4(5):e5678. Epub 2009 May 25.

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005678PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682576PMC
May 2009

Cytoskeletal regulation: coordinating actin and microtubule dynamics in membrane trafficking.

Curr Biol 2008 Sep;18(18):R873-5

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1016/j.cub.2008.07.059DOI Listing
September 2008

IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions.

Trends Cell Biol 2008 Feb 22;18(2):52-60. Epub 2008 Jan 22.

IFOM (FIRC Institute for Molecular Oncology) - Foundation, Via Adamello 16, 20139 Milan, Italy; School of Medicine, University of Milan, 20122 Milan, Italy.

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http://dx.doi.org/10.1016/j.tcb.2007.12.002DOI Listing
February 2008

Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.

Mol Biol Cell 2006 Sep 14;17(9):3729-44. Epub 2006 Jun 14.

Ludwig Institute for Cancer Research, Royal Free and University College Hospital Medical School, London W1W 7BS, United Kingdom.

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http://dx.doi.org/10.1091/mbc.e05-11-1083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1593155PMC
September 2006

Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells.

J Cell Sci 2006 Aug 25;119(Pt 16):3316-24. Epub 2006 Jul 25.

Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, NC, USA.

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http://jcs.biologists.org/content/joces/119/16/3316.full.pdf
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http://jcs.biologists.org/cgi/doi/10.1242/jcs.03076
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http://dx.doi.org/10.1242/jcs.03076DOI Listing
August 2006

Sos-mediated activation of rac1 by p66shc.

J Cell Biol 2006 Mar 6;172(6):817-22. Epub 2006 Mar 6.

Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1083/jcb.200506001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063726PMC
March 2006

Protein complexes regulating Arp2/3-mediated actin assembly.

Curr Opin Cell Biol 2006 Feb 15;18(1):4-10. Epub 2005 Dec 15.

Signalling and Motility Group, German Research Centre for Biotechnology (GBF), Mascheroder Weg 1, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.ceb.2005.12.003DOI Listing
February 2006

WAVE2 signaling mediates invasion of polarized epithelial cells by Salmonella typhimurium.

J Biol Chem 2005 Aug 1;280(33):29849-55. Epub 2005 Jun 1.

Department of Cell Biology, University of Virginia Health Sciences Center, Charlottesville, 22908-0732, USA.

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http://dx.doi.org/10.1074/jbc.M500617200DOI Listing
August 2005

WASP-related proteins, Abi1 and Ena/VASP are required for Listeria invasion induced by the Met receptor.

J Cell Sci 2005 Apr 15;118(Pt 7):1537-47. Epub 2005 Mar 15.

Unité des Interactions Bactéries-Cellules, Institut Pasteur, INSERM U604, INRA USC2020, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1242/jcs.02285DOI Listing
April 2005

Eps8 controls actin-based motility by capping the barbed ends of actin filaments.

Nat Cell Biol 2004 Dec 21;6(12):1180-8. Epub 2004 Nov 21.

IFOM Istituto FIRC di Oncologia Molecolare Via Adamello 16, 20139, Milan, Italy.

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http://dx.doi.org/10.1038/ncb1199DOI Listing
December 2004

Regulation of actin dynamics by WASP and WAVE family proteins.

Trends Cell Biol 2004 Jun;14(6):303-11

German Research Centre for Biotechnology, Department of Cell Biology, Mascheroder Weg 1, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.tcb.2004.04.007DOI Listing
June 2004

Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.

Nature 2004 May;429(6989):309-14

Istituto Europeo di Oncologia, Via Ripamonti 435, 20141 Milan, Italy.

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http://dx.doi.org/10.1038/nature02542DOI Listing
May 2004

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

Nat Cell Biol 2004 Apr 28;6(4):319-27. Epub 2004 Mar 28.

IFOM Istituto FIRC di Oncologia Molecolare Via Adamello 16, 20134, Milan, Italy.

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http://dx.doi.org/10.1038/ncb1105DOI Listing
April 2004

Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation.

Nat Cell Biol 2004 Mar 22;6(3):268-74. Epub 2004 Feb 22.

Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti, 435, 20141 Milan, Italy.

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http://dx.doi.org/10.1038/ncb1096DOI Listing
March 2004

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

EMBO J 2004 Feb 5;23(4):749-59. Epub 2004 Feb 5.

German Research Centre for Biotechnology, Department of Cell Biology, Braunschweig, Germany.

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http://emboj.embopress.org/cgi/doi/10.1038/sj.emboj.7600084
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http://dx.doi.org/10.1038/sj.emboj.7600084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC380996PMC
February 2004

In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure.

Genomics 2003 Feb;81(2):234-44

Department of Medical Biochemistry, University of Göteborg, Sweden.

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http://dx.doi.org/10.1016/s0888-7543(03)00002-8DOI Listing
February 2003

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

J Cell Biol 2003 Jan 6;160(1):17-23. Epub 2003 Jan 6.

Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy.

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http://dx.doi.org/10.1083/jcb.200206079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172734PMC
January 2003

Eps8 in the midst of GTPases.

Int J Biochem Cell Biol 2002 Oct;34(10):1178-83

Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti, 435, 20141 Milan, Italy.

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http://dx.doi.org/10.1016/s1357-2725(02)00064-xDOI Listing
October 2002

Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.

J Cell Biol 2002 Jan 3;156(1):125-36. Epub 2002 Jan 3.

Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti, 435, 20141 Milan, Italy.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200108035
Publisher Site
http://dx.doi.org/10.1083/jcb.200108035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173577PMC
January 2002