Publications by authors named "Giorgio Fedele"

50Publications

Intracellular protein kinase CK2 inhibition by ferulic acid-based trimodal nanodevice.

Int J Biol Macromol 2020 Dec 30;165(Pt A):701-712. Epub 2020 Sep 30.

Department of Comparative Biomedicine and Food Science, Agripolis Campus, University of Padova, viale dell'Università 16, 35020 Legnaro, Italy. Electronic address:

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December 2020

Human Immune Responses to Pertussis Vaccines.

Adv Exp Med Biol 2019 ;1183:99-113

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

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February 2020

Diagnostic performance of commercial serological assays measuring Bordetella pertussis IgG antibodies.

Diagn Microbiol Infect Dis 2018 Mar 13;90(3):157-162. Epub 2017 Nov 13.

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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March 2018

Nitric oxide interacts with monoamine oxidase to modulate aggression and anxiety-like behaviour.

Eur Neuropsychopharmacol 2020 01 23;30:30-43. Epub 2017 Sep 23.

Department of Neuroscience, Psychology and Behaviour, University of Leicester, University Rd, Leicester, LE1 7RH, UK. Electronic address:

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January 2020

Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity.

Toxins (Basel) 2017 09 21;9(10). Epub 2017 Sep 21.

Institute of Microbiology of the CAS, v. v. i., Prague 142 20, Czech Republic.

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September 2017

Pertussis in infants and the resurgence of a vaccine preventable disease: what to do? Commentary.

Ann Ist Super Sanita 2017 Apr-Jun;53(2):100-103

Dipartimento di Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy.

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April 2018

Geographical analysis of diapause inducibility in European Drosophila melanogaster populations.

J Insect Physiol 2017 04 25;98:238-244. Epub 2017 Jan 25.

Department of Genetics, University of Leicester, Leicester LE1 7RH, UK; Department of Evolutionary & Environmental Biology, University of Haifa, Haifa 3498838, Israel.

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April 2017

Does Breastfeeding Protect Young Infants From Pertussis? Case-control Study and Immunologic Evaluation.

Pediatr Infect Dis J 2017 03;36(3):e48-e53

From the *Multifactorial Disease and Complex Phenotype Research Area, Bambino Gesù Children's Hospital; †Department of Pediatrics, Bambino Gesù Children Hospital IRCSS; ‡Department of Pediatrics, Sapienza University of Rome; §Immunology Unit, Immunology and Pharmacal Therapy Area, Bambino Gesù Children Hospital IRCSS; and ¶Department of Infectious, Parasitic & Immuno-mediated Disease, Istituto Superiore di Sanità, Rome, Italy.

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March 2017

Parents as source of pertussis transmission in hospitalized young infants.

Infection 2017 Apr 10;45(2):171-178. Epub 2016 Sep 10.

Department of Infectious, Parasitic, and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

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April 2017

T-cell immune responses to Bordetella pertussis infection and vaccination.

Pathog Dis 2015 Oct 4;73(7). Epub 2015 Aug 4.

Anti-Infectious Immunity Unit, Department of Infectious Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.

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October 2015

Unconventional, adenosine-producing suppressor T cells induced by dendritic cells exposed to BPZE1 pertussis vaccine.

J Leukoc Biol 2015 Oct 18;98(4):631-9. Epub 2015 Jun 18.

*Anti-Infectious Immunity Unit, Department of Infectious Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy; INSERM U1019, Lille, France; CNRS UMR8204, Lille, France; Institut Pasteur de Lille, Center for Infection and Immunity, Lille, France; University of Lille Nord de France, Lille, France; Laboratory of Immunogenetics, Department of Medical Sciences and CERMS, University of Torino, Torino, Italy; **Transplantation Immunology Service, Città della Salute e della Scienza Hospital, Torino, Italy.

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October 2015

An electromagnetic field disrupts negative geotaxis in Drosophila via a CRY-dependent pathway.

Nat Commun 2014 Jul 14;5:4391. Epub 2014 Jul 14.

Department of Genetics, University of Leicester, Leicester LE1 7RH, UK.

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July 2014

A Drosophila RNAi collection is subject to dominant phenotypic effects.

Nat Methods 2014 Mar;11(3):222-3

Department of Genetics, University of Leicester, Leicester, UK.

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March 2014

CD38 ligation in peripheral blood mononuclear cells of myeloma patients induces release of protumorigenic IL-6 and impaired secretion of IFNγ cytokines and proliferation.

Mediators Inflamm 2013 30;2013:564687. Epub 2013 Dec 30.

Department of Infectious, Parasitic and Immune-mediated Diseases, Anti-infectious Immunity Unit, Istituto Superiore di Sanità, 00161 Rome, Italy.

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June 2014

The virulence factors of Bordetella pertussis: talented modulators of host immune response.

Arch Immunol Ther Exp (Warsz) 2013 Dec 18;61(6):445-57. Epub 2013 Aug 18.

Department of Infectious, Parasitic, and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161, Rome, Italy,

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December 2013

The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia.

Haematologica 2013 Jun 8;98(6):953-63. Epub 2013 Jan 8.

Human Genetics Foundation (HuGeF) and Department of Medical Sciences, University of Turin, Turin, Italy.

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June 2013

Hepatitis B specific T cell immunity induced by primary vaccination persists independently of the protective serum antibody level.

Vaccine 2013 Jan 19;31(3):506-13. Epub 2012 Nov 19.

Anti-Infectious Immunity Unit, Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.

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January 2013

Chlamydia pneumoniae modulates human monocyte-derived dendritic cells functions driving the induction of a Type 1/Type 17 inflammatory response.

Microbes Infect 2013 Feb 16;15(2):105-14. Epub 2012 Nov 16.

Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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February 2013

Attenuated Bordetella pertussis vaccine candidate BPZE1 promotes human dendritic cell CCL21-induced migration and drives a Th1/Th17 response.

J Immunol 2011 May 23;186(9):5388-96. Epub 2011 Mar 23.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, 00161 Rome, Italy.

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May 2011

Immunomodulatory activities of surface-layer proteins obtained from epidemic and hypervirulent Clostridium difficile strains.

J Med Microbiol 2011 Aug 24;60(Pt 8):1162-1167. Epub 2011 Feb 24.

Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

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August 2011

A natural pertactin deficient strain of Bordetella pertussis shows improved entry in human monocyte-derived dendritic cells.

New Microbiol 2009 Apr;32(2):159-66

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

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April 2009

IFN-gamma arms human dendritic cells to perform multiple effector functions.

J Immunol 2008 Feb;180(3):1471-81

Department of Infectious, Parasitic, and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

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February 2008

Use of whole-blood samples in in-house bulk and single-cell antigen-specific gamma interferon assays for surveillance of Mycobacterium tuberculosis infections.

Clin Vaccine Immunol 2008 Feb 21;15(2):327-37. Epub 2007 Nov 21.

Department of Infectious, Parasitic and Immune-Mediated Diseases, Centre of Epidemiology, Surveillance and Health Promotion, Istituto Superiore di Sanità, Rome 00161, Italy.

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February 2008

Lipooligosaccharide from Bordetella pertussis induces mature human monocyte-derived dendritic cells and drives a Th2 biased response.

Microbes Infect 2007 Jun 12;9(7):855-63. Epub 2007 Mar 12.

Department of Infectious, Parasitic and Immune-mediated Diseases, Anti-infectious Immunity Unit, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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June 2007

Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells.

Microbes Infect 2006 Sep 8;8(11):2640-6. Epub 2006 Aug 8.

Department of Infectious, Parasitic and Immune-mediated Diseases, Anti-Infectious Immunity Unit, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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September 2006

60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells.

Microbes Infect 2006 Mar 11;8(3):714-20. Epub 2006 Jan 11.

Department of Infectious, Parasitic, and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy.

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March 2006

CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells.

Blood 2006 Mar 17;107(6):2392-9. Epub 2005 Nov 17.

Department of Infectious, Parasitic, and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

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March 2006

Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression.

Infect Immun 2005 Mar;73(3):1590-7

Department of Infectious, Parasitic, and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy.

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March 2005