Giorgio Carta

Giorgio Carta

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Giorgio Carta

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Dynamics of competitive binding and separation of monoclonal antibody monomer-dimer mixtures in ceramic hydroxyapatite columns.

J Chromatogr A 2020 Jan 30;1609:460504. Epub 2019 Aug 30.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2019.460504DOI Listing
January 2020

Chromatographic behavior of bivalent bispecific antibodies on hydrophobic interaction chromatography columns.

J Chromatogr A 2020 Jan 10:460836. Epub 2020 Jan 10.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2019.460836DOI Listing
January 2020

Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. II. Biomolecular perspectives.

J Chromatogr A 2019 Sep 9;1601:133-144. Epub 2019 Apr 9.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2019.04.013DOI Listing
September 2019

Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. I. Experimental observations and phenomenological model.

J Chromatogr A 2019 Sep 21;1601:121-132. Epub 2019 Apr 21.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2019.04.012DOI Listing
September 2019

Systematic Interpolation Method Predicts Antibody Monomer-Dimer Separation by Gradient Elution Chromatography at High Protein Loads.

Biotechnol J 2019 Mar 11;14(3):e1800132. Epub 2018 Jun 11.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, Virginia, 22904, USA.

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http://doi.wiley.com/10.1002/biot.201800132
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http://dx.doi.org/10.1002/biot.201800132DOI Listing
March 2019

Competitive binding of monoclonal antibody monomer-dimer mixtures on ceramic hydroxyapatite.

J Chromatogr A 2019 Feb 13;1587:136-145. Epub 2018 Dec 13.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.12.023DOI Listing
February 2019

Rapid and Sensitive Detection of the Interaction of Human Papillomavirus Virus-Like Particles with Yeast Whole Cell RNA Using Biolayer Interferometry.

Biotechnol J 2019 Jan 21;14(1):e1800303. Epub 2018 Aug 21.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, 22904, Charlottesville, Virginia.

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http://doi.wiley.com/10.1002/biot.201800303
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http://dx.doi.org/10.1002/biot.201800303DOI Listing
January 2019

Hindered diffusion of proteins in mixture adsorption on porous anion exchangers and impact on flow-through purification of large proteins.

J Chromatogr A 2019 Jan 23;1585:121-130. Epub 2018 Nov 23.

Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.11.060DOI Listing
January 2019

Gradient elution behavior of proteins in hydrophobic interaction chromatography with a U-shaped retention factor curve under overloaded conditions.

J Chromatogr A 2018 Nov 7;1578:28-34. Epub 2018 Oct 7.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.10.003DOI Listing
November 2018

Chemical modification of protein A chromatography ligands with polyethylene glycol. I: Effects on IgG adsorption equilibrium, kinetics, and transport.

J Chromatogr A 2018 Apr 9;1546:77-88. Epub 2018 Mar 9.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.03.011DOI Listing
April 2018

Chemical modification of protein a chromatography ligands with polyethylene glycol. II: Effects on resin robustness and process selectivity.

J Chromatogr A 2018 Apr 24;1546:89-96. Epub 2018 Feb 24.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219673183018
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http://dx.doi.org/10.1016/j.chroma.2018.02.024DOI Listing
April 2018

Gradient elution behavior of proteins in hydrophobic interaction chromatography with U-shaped retention factor curves.

J Chromatogr A 2018 Apr 9;1547:53-61. Epub 2018 Mar 9.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.03.012DOI Listing
April 2018

Polyclonal and monoclonal IgG binding on protein A resins-Evidence of competitive binding effects.

Biotechnol Bioeng 2017 08 6;114(8):1803-1812. Epub 2017 Jun 6.

Department of Chemical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213.

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http://doi.wiley.com/10.1002/bit.26286
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http://dx.doi.org/10.1002/bit.26286DOI Listing
August 2017

Separation of antibody monomer-dimer mixtures by frontal analysis.

J Chromatogr A 2017 Jun 10;1500:96-104. Epub 2017 Apr 10.

Department of Chemical Engineering, University of Virginia, Charlottesville VA 22904, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2017.04.014DOI Listing
June 2017

Systematic interpolation method predicts protein chromatographic elution with salt gradients, pH gradients and combined salt/pH gradients.

Biotechnol J 2017 Mar 24;12(3). Epub 2017 Jan 24.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1002/biot.201600636DOI Listing
March 2017

Structural and performance characteristics of representative anion exchange resins used for weak partitioning chromatography.

Biotechnol Prog 2017 03 28;33(2):425-434. Epub 2017 Jan 28.

Dept. of Chemical Engineering, University of Virginia, Charlottesville, VA.

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http://doi.wiley.com/10.1002/btpr.2412
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http://dx.doi.org/10.1002/btpr.2412DOI Listing
March 2017

Surface induced three-peak elution behavior of a monoclonal antibody during cation exchange chromatography.

J Chromatogr A 2016 Nov 26;1474:85-94. Epub 2016 Oct 26.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2016.10.061DOI Listing
November 2016

Comparison of perfusion media and monoliths for protein and virus-like particle chromatography.

J Chromatogr A 2016 May 31;1447:72-81. Epub 2016 Mar 31.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2016.03.077DOI Listing
May 2016

Structural and functional characteristics of virgin and fouled Protein A MabSelect resin cycled in a monoclonal antibody purification process.

Biotechnol Bioeng 2016 Feb 3;113(2):367-75. Epub 2015 Sep 3.

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, 22904.

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http://dx.doi.org/10.1002/bit.25708DOI Listing
February 2016

Nature of foulants and fouling mechanism in the Protein A MabSelect resin cycled in a monoclonal antibody purification process.

Biotechnol Bioeng 2016 Jan 18;113(1):141-9. Epub 2015 Oct 18.

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia.

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http://dx.doi.org/10.1002/bit.25706DOI Listing
January 2016

Systematic interpolation method predicts protein chromatographic elution from batch isotherm data without a detailed mechanistic isotherm model.

Biotechnol J 2015 Sep 24;10(9):1400-11. Epub 2015 Jun 24.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1002/biot.201500089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703226PMC
September 2015

Adsorption equilibrium and kinetics of monomer-dimer monoclonal antibody mixtures on a cation exchange resin.

J Chromatogr A 2015 Jul 23;1402:46-59. Epub 2015 May 23.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, United States. Electronic address:

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http://link.springer.com/content/pdf/10.1007%2Fs10450-015-97
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http://linkinghub.elsevier.com/retrieve/pii/S002196731500681
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http://dx.doi.org/10.1016/j.chroma.2015.05.007DOI Listing
July 2015

Unfolding and aggregation of monoclonal antibodies on cation exchange columns: effects of resin type, load buffer, and protein stability.

J Chromatogr A 2015 Apr 21;1388:184-94. Epub 2015 Feb 21.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2015.02.047DOI Listing
April 2015

Effects of polymer graft properties on protein adsorption and transport in ion exchange chromatography: a multiscale modeling study.

Langmuir 2015 Apr 30;31(14):4176-87. Epub 2015 Mar 30.

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia 22904, United States.

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http://dx.doi.org/10.1021/la504768gDOI Listing
April 2015

Particle size effects on protein and virus-like particle adsorption on perfusion chromatography media.

J Chromatogr A 2015 Jan 4;1375:92-100. Epub 2014 Dec 4.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2014.11.083DOI Listing
January 2015

Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry.

J Chromatogr A 2014 Aug 19;1356:129-37. Epub 2014 Jun 19.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2014.06.038DOI Listing
August 2014

Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part I. Chromatographic elution and batch adsorption behavior.

J Chromatogr A 2014 Aug 19;1356:117-28. Epub 2014 Jun 19.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219673140096
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http://dx.doi.org/10.1016/j.chroma.2014.06.037DOI Listing
August 2014

Adsorption of polyethylene-glycolated bovine serum albumin on macroporous and polymer-grafted anion exchangers.

J Chromatogr A 2014 Jan 22;1326:29-38. Epub 2013 Dec 22.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2013.12.007DOI Listing
January 2014

Protein and virus-like particle adsorption on perfusion chromatography media.

J Chromatogr A 2013 Jul 9;1297:96-105. Epub 2013 May 9.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904, USA.

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http://dx.doi.org/10.1016/j.chroma.2013.04.062DOI Listing
July 2013

Structure and protein adsorption mechanisms of clean and fouled tentacle-type anion exchangers used in a monoclonal antibody polishing step.

J Chromatogr A 2013 Feb 9;1278:116-25. Epub 2013 Jan 9.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904, USA.

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http://dx.doi.org/10.1016/j.chroma.2013.01.006DOI Listing
February 2013

Multicomponent adsorption of monoclonal antibodies on macroporous and polymer grafted cation exchangers.

J Chromatogr A 2012 Nov 26;1264:48-56. Epub 2012 Sep 26.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2012.09.064DOI Listing
November 2012

Predicting protein dynamic binding capacity from batch adsorption tests.

Authors:
Giorgio Carta

Biotechnol J 2012 Oct 14;7(10):1216-20. Epub 2012 Jun 14.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA.

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http://dx.doi.org/10.1002/biot.201200136DOI Listing
October 2012

Counterion effects on protein adsorption equilibrium and kinetics in polymer-grafted cation exchangers.

J Chromatogr A 2012 Aug 11;1253:83-93. Epub 2012 Jul 11.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22901, USA.

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http://dx.doi.org/10.1016/j.chroma.2012.06.100DOI Listing
August 2012

Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds.

J Med Chem 2012 Jun 24;55(11):4978-89. Epub 2012 May 24.

Molecular Design Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/jm300068nDOI Listing
June 2012

Consensus Computational Ligand-Based Design for the Identification of Novel Modulators of Human Estrogen Receptor Alpha.

Mol Inform 2012 Apr 14;31(3-4):246-58. Epub 2012 Mar 14.

Molecular Design Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland tel: +353-1-8963527, fax: +353-1-6772400.

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http://dx.doi.org/10.1002/minf.201100127DOI Listing
April 2012

Protein adsorption and transport in cation exchangers with a rigid backbone matrix with and without polymeric surface extenders.

Biotechnol Prog 2011 Sep-Oct;27(5):1264-72. Epub 2011 May 23.

Dept. of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904, USA.

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http://doi.wiley.com/10.1002/btpr.643
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http://dx.doi.org/10.1002/btpr.643DOI Listing
February 2012

Meeting report: 24th International symposium, exhibit and workshops on preparative and process chromatography - PREP2011.

Authors:
Giorgio Carta

Biotechnol J 2011 Dec 1;6(12):1435-6. Epub 2011 Sep 1.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA.

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http://doi.wiley.com/10.1002/biot.201100375
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http://dx.doi.org/10.1002/biot.201100375DOI Listing
December 2011

Adsorption kinetics of deamidated antibody variants on macroporous and dextran-grafted cation exchangers. III. Microscopic studies.

J Chromatogr A 2011 Nov 9;1218(44):8027-35. Epub 2011 Sep 9.

Department of Chemical Engineering University of Virginia 102 Engineers' Way, Charlottesville, VA 22904-4741 USA.

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http://dx.doi.org/10.1016/j.chroma.2011.09.010DOI Listing
November 2011

Identification of plasmepsin inhibitors as selective anti-malarial agents using ligand based drug design.

Bioorg Med Chem Lett 2011 Jun 8;21(11):3335-41. Epub 2011 Apr 8.

Molecular Design Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X110046
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http://dx.doi.org/10.1016/j.bmcl.2011.04.015DOI Listing
June 2011

Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: II. Adsorption kinetics.

J Chromatogr A 2011 Mar 22;1218(11):1530-7. Epub 2011 Jan 22.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2011.01.050DOI Listing
March 2011

Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: I. Adsorption equilibrium.

J Chromatogr A 2011 Mar 22;1218(11):1519-29. Epub 2011 Jan 22.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2011.01.049DOI Listing
March 2011

pH transients in hydroxyapatite chromatography columns-Effects of operating conditions and media properties.

J Chromatogr A 2010 Nov 11;1217(48):7573-8. Epub 2010 Oct 11.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2010.10.026DOI Listing
November 2010

Apolipoprotein A-I(Milano) anion exchange chromatography: Self association and adsorption equilibrium.

Biotechnol J 2010 Oct;5(10):1028-39

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1002/biot.201000221DOI Listing
October 2010

Apolipoprotein A-I(Milano) anion exchange chromatography: mass transfer and adsorption kinetics.

Biotechnol J 2010 Oct;5(10):1040-9

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1002/biot.201000222DOI Listing
October 2010

'tieredScreen' - Layered Virtual Screening Tool for the Identification of Novel Estrogen Receptor Alpha Modulators.

Mol Inform 2010 May 17;29(5):421-30. Epub 2010 May 17.

Molecular Design Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland, Telephone: +353-1-8961634, Fax: +353-1-6762400.

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http://dx.doi.org/10.1002/minf.201000034DOI Listing
May 2010

Evaluation of polymer matrices for an adsorptive approach to plasma detoxification.

Biomaterials 2010 Apr 31;31(10):2857-65. Epub 2009 Dec 31.

Department of Chemical Engineering, University of Virginia, 102 Engineer's Way, Charlottesville, VA 22904, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2009.12.036DOI Listing
April 2010

pH Transients in hydroxyapatite chromatography columns-experimental evidence and phenomenological modeling.

J Chromatogr A 2010 Apr 6;1217(14):2123-31. Epub 2010 Feb 6.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00219673100016
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http://dx.doi.org/10.1016/j.chroma.2010.02.004DOI Listing
April 2010

Virtual screening for the identification of novel nonsteroidal glucocorticoid modulators.

J Med Chem 2010 Apr;53(8):3065-74

Molecular Design Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/jm901452yDOI Listing
April 2010

IgG adsorption on a new protein A adsorbent based on macroporous hydrophilic polymers. I. Adsorption equilibrium and kinetics.

J Chromatogr A 2009 Nov 11;1216(47):8339-47. Epub 2009 Sep 11.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00219673090135
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http://dx.doi.org/10.1016/j.chroma.2009.09.017DOI Listing
November 2009

IgG adsorption on a new protein A adsorbent based on macroporous hydrophilic polymers II. Pressure-flow curves and optimization for capture.

J Chromatogr A 2009 Nov 18;1216(47):8348-54. Epub 2009 Sep 18.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002196730901389
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http://dx.doi.org/10.1016/j.chroma.2009.09.033DOI Listing
November 2009

Protein adsorption and transport in agarose and dextran-grafted agarose media for ion exchange chromatography: Effect of ionic strength and protein characteristics.

J Chromatogr A 2009 May 20;1216(20):4465-74. Epub 2009 Mar 20.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00219673090044
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http://dx.doi.org/10.1016/j.chroma.2009.03.044DOI Listing
May 2009

Rational structure-based drug design and optimization in the ligand-binding domain of the glucocorticoid receptor-α.

Future Med Chem 2009 May;1(2):345-59

School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://www.future-science.com/doi/10.4155/fmc.09.21
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http://dx.doi.org/10.4155/fmc.09.21DOI Listing
May 2009

Separation of protein charge variants with induced pH gradients using anion exchange chromatographic columns.

Biotechnol Prog 2008 Sep-Oct;24(5):1096-106

Dept of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://doi.wiley.com/10.1002/btpr.53
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http://dx.doi.org/10.1002/btpr.53DOI Listing
April 2009

Rapid monoclonal antibody adsorption on dextran-grafted agarose media for ion-exchange chromatography.

J Chromatogr A 2008 Nov 4;1211(1-2):70-9. Epub 2008 Oct 4.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741 USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002196730801676
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http://dx.doi.org/10.1016/j.chroma.2008.09.096DOI Listing
November 2008

Theory and applications of refractive index-based optical microscopy to measure protein mass transfer in spherical adsorbent particles.

J Chromatogr A 2008 Apr 29;1188(2):242-54. Epub 2008 Feb 29.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2008.02.076DOI Listing
April 2008

Protein separations with induced pH gradients using cation-exchange chromatographic columns containing weak acid groups.

J Chromatogr A 2008 Feb 26;1181(1-2):83-94. Epub 2007 Dec 26.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2007.12.054DOI Listing
February 2008

Unbiasing scoring functions: a new normalization and rescoring strategy.

J Chem Inf Model 2007 Jul-Aug;47(4):1564-71. Epub 2007 Jun 7.

Molecular Design Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/ci600471mDOI Listing
October 2007

Patterns of protein adsorption in chromatographic particles visualized by optical microscopy.

J Chromatogr A 2007 Aug 23;1160(1-2):206-14. Epub 2007 May 23.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2007.05.058DOI Listing
August 2007

On the effects of permuted input on conformational sampling of drug-like molecules: an evaluation of stochastic proximity embedding.

Chem Biol Drug Des 2007 Aug;70(2):123-33

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 665 Stockton Drive, Exton, PA 19341, USA.

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http://doi.wiley.com/10.1111/j.1747-0285.2007.00538.x
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http://dx.doi.org/10.1111/j.1747-0285.2007.00538.xDOI Listing
August 2007

Protein adsorption and transport in agarose and dextran-grafted agarose media for ion exchange chromatography.

J Chromatogr A 2007 Apr 17;1146(2):202-15. Epub 2007 Feb 17.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002196730700254
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http://dx.doi.org/10.1016/j.chroma.2007.02.041DOI Listing
April 2007

pH transitions in cation exchange chromatographic columns containing weak acid groups.

J Chromatogr A 2007 Feb 15;1142(1):19-31. Epub 2006 Sep 15.

Department of Chemical Engineering, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2006.08.066DOI Listing
February 2007

Considerations in compound database preparation--"hidden" impact on virtual screening results.

J Chem Inf Model 2005 Nov-Dec;45(6):1908-19

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, Ireland.

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http://pubs.acs.org/doi/abs/10.1021/ci050185z
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http://dx.doi.org/10.1021/ci050185zDOI Listing
June 2006

Radiotracer measurements of protein mass transfer: kinetics in ion exchange media.

Biotechnol J 2006 Jun;1(6):665-74

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA.

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http://doi.wiley.com/10.1002/biot.200600023
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http://dx.doi.org/10.1002/biot.200600023DOI Listing
June 2006

Permuting input for more effective sampling of 3D conformer space.

J Comput Aided Mol Des 2006 Mar 14;20(3):179-90. Epub 2006 Jul 14.

Molecular Design Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland,

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http://dx.doi.org/10.1007/s10822-006-9044-4DOI Listing
March 2006

Giorgio Carta: bioseparations.

Authors:
Giorgio Carta

Biotechnol J 2006 Jan;1(1):29-30

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http://dx.doi.org/10.1002/biot.200690009DOI Listing
January 2006

Two-component protein adsorption kinetics in porous ion exchange media.

J Chromatogr A 2005 Jun;1079(1-2):105-15

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2005.03.007DOI Listing
June 2005

Properties and performance of novel high-resolution/high-permeability ion-exchange media for protein chromatography.

J Chromatogr A 2005 Mar;1069(1):43-52

Department of Chemical Engineering University of Virginia, P.O. Box 400741, Charlottesville, VA 22904-4741, USA.

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http://dx.doi.org/10.1016/j.chroma.2004.08.114DOI Listing
March 2005

Asymmetric synthesis with immobilized yeast in organic solvents: equilibrium conversion and effect of reactant partitioning on whole cell biocatalysis.

Biotechnol Prog 2003 Mar-Apr;19(2):389-95

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia 22904-4741, USA.

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http://dx.doi.org/10.1021/bp020134bDOI Listing
March 2004

Protein adsorption on novel acrylamido-based polymeric ion-exchangers. IV. Effects of protein size on adsorption capacity and rate.

J Chromatogr A 2002 Sep;971(1-2):105-16

Department of Chemical Engineering, University of Virginia, Charlottesville 22903-2442, USA.

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http://dx.doi.org/10.1016/s0021-9673(02)01027-0DOI Listing
September 2002