Publications by authors named "Giorgio Bernardi"

100Publications

The Genomic Code: A Pervasive Encoding/Molding of Chromatin Structures and a Solution of the "Non-Coding DNA" Mystery.

Authors:
Giorgio Bernardi

Bioessays 2019 12 8;41(12):e1900106. Epub 2019 Nov 8.

Science Department, Roma Tre University, Viale Marconi 446, 00146, Rome, Italy.

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http://dx.doi.org/10.1002/bies.201900106DOI Listing
December 2019

The formation of chromatin domains involves a primary step based on the 3-D structure of DNA.

Authors:
Giorgio Bernardi

Sci Rep 2018 12 13;8(1):17821. Epub 2018 Dec 13.

Science Department, Roma Tre University, Viale Marconi 446, 00146, Rome, Italy.

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http://dx.doi.org/10.1038/s41598-018-35851-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292937PMC
December 2018

The short-sequence design of DNA and its involvement in the 3-D structure of the genome.

Sci Rep 2018 12 13;8(1):17820. Epub 2018 Dec 13.

Science Department, Roma Tre University, Viale Marconi 446, 00146, Rome, Italy.

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http://dx.doi.org/10.1038/s41598-018-35864-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292894PMC
December 2018

An Isochore Framework Underlies Chromatin Architecture.

PLoS One 2017 6;12(1):e0168023. Epub 2017 Jan 6.

Science Department, Roma Tre University, Viale Marconi, Rome, Italy, and Stazione Zoologica Anton Dohrn, Villa Comunale, Naples, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168023PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218411PMC
August 2017

The Anolis Lizard Genome: An Amniote Genome without Isochores?

Genome Biol Evol 2016 Apr 13;8(4):1048-55. Epub 2016 Apr 13.

Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Naples, Italy Science Department, Roma Tre University, Rome, Italy

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http://dx.doi.org/10.1093/gbe/evw056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860688PMC
April 2016

Genome Organization and Chromosome Architecture.

Authors:
Giorgio Bernardi

Cold Spring Harb Symp Quant Biol 2015 22;80:83-91. Epub 2016 Jan 22.

Science Department, Roma Tre University, 00146 Rome, Italy Stazione Zoologica Anton Dohrn, 80121 Naples, Italy.

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http://dx.doi.org/10.1101/sqb.2015.80.027318DOI Listing
January 2018

Editorial.

Gene 2016 Feb;576(2 Pt 1):592

The University of Rome, Italy.

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http://dx.doi.org/10.1016/j.gene.2015.11.017DOI Listing
February 2016

Segmenting the Human Genome into Isochores.

Evol Bioinform Online 2015 25;11:253-61. Epub 2015 Nov 25.

National Research Council, Institute for Biomedical Technologies, Segrate, Milan, Italy. ; Science Department, Rome 3 University, Rome, Italy.

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http://journals.sagepub.com/doi/10.4137/EBO.S27693
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http://dx.doi.org/10.4137/EBO.S27693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662427PMC
December 2015

Chromosome Architecture and Genome Organization.

Authors:
Giorgio Bernardi

PLoS One 2015 30;10(11):e0143739. Epub 2015 Nov 30.

Science Department, Roma Tre University, Marconi, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143739PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664426PMC
June 2016

Sodium valproate in migraine without aura and medication overuse headache: a randomized controlled trial.

Eur Neuropsychopharmacol 2014 Aug 5;24(8):1289-97. Epub 2014 Apr 5.

Clinica Neurologica, Azienda Ospedaliera - Università di Perugia, Italy; IRCCS Fondazione "S. Lucia", Roma, Italy.

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http://dx.doi.org/10.1016/j.euroneuro.2014.03.010DOI Listing
August 2014

Compositional patterns in the genomes of unicellular eukaryotes.

BMC Genomics 2013 Nov 5;14:755. Epub 2013 Nov 5.

Laboratory of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.

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http://dx.doi.org/10.1186/1471-2164-14-755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007698PMC
November 2013

Systemic delivery of recombinant brain derived neurotrophic factor (BDNF) in the R6/2 mouse model of Huntington's disease.

PLoS One 2013 20;8(5):e64037. Epub 2013 May 20.

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS Hospital at the European Center for Brain Research, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064037PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659095PMC
December 2013

Neurosteroid and neurotransmitter alterations in Parkinson's disease.

Front Neuroendocrinol 2013 Apr 4;34(2):132-42. Epub 2013 Apr 4.

Experimental Neurology, Fondazione Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.1016/j.yfrne.2013.03.001DOI Listing
April 2013

Phosphodiesterase 10A (PDE10A) localization in the R6/2 mouse model of Huntington's disease.

Neurobiol Dis 2013 Apr 7;52:104-16. Epub 2012 Dec 7.

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS Hospital, Rome, Italy.

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http://dx.doi.org/10.1016/j.nbd.2012.11.016DOI Listing
April 2013

The genome: an isochore ensemble and its evolution.

Authors:
Giorgio Bernardi

Ann N Y Acad Sci 2012 Sep;1267:31-4

Department of Biology, University Rome, Rome, Italy.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06591.xDOI Listing
September 2012

The impact of rotigotine on cardiovascular autonomic function in early Parkinson's disease.

Eur Neurol 2012 28;68(3):187-92. Epub 2012 Aug 28.

Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1159/000339000DOI Listing
March 2013

Cholinergic dysfunction alters synaptic integration between thalamostriatal and corticostriatal inputs in DYT1 dystonia.

J Neurosci 2012 Aug;32(35):11991-2004

Department of Neuroscience, University Tor Vergata/Laboratory of Neurophysiology and Synaptic Plasticity, Fondazione Santa Lucia Istituto di Ricovero e Cura a Carattere Scientifico, 00143 Rome, Italy.

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http://dx.doi.org/10.1523/JNEUROSCI.0041-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471539PMC
August 2012

Dopamine D₂-agonist rotigotine effects on cortical excitability and central cholinergic transmission in Alzheimer's disease patients.

Neuropharmacology 2013 Jan 1;64:108-13. Epub 2012 Aug 1.

Clinica Neurologica, Dipartimento di Neuroscienze, Centro di Riferimento per la Malattia di Alzheimer, Università di Roma Tor Vergata, Viale Oxford 81, 00133 Roma, Italy.

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http://dx.doi.org/10.1016/j.neuropharm.2012.07.015DOI Listing
January 2013

Sequence analysis of serum albumins reveals the molecular evolution of ligand recognition properties.

J Biomol Struct Dyn 2012 ;29(6):691-701

Department of Biomedical, Informatics and Communication Sciences, University of Insubria, Busto Arsizio (VA), Italy.

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http://dx.doi.org/10.1080/07391102.2011.672632DOI Listing
August 2012

Short interval intracortical facilitation correlates with the degree of disability in multiple sclerosis.

Brain Stimul 2013 Jan 24;6(1):67-71. Epub 2012 Feb 24.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, 00133 Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X120001
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http://dx.doi.org/10.1016/j.brs.2012.02.001DOI Listing
January 2013

Inflammation inhibits GABA transmission in multiple sclerosis.

Mult Scler 2012 Nov 14;18(11):1633-5. Epub 2012 Mar 14.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1177/1352458512440207DOI Listing
November 2012

Plasmin system of Alzheimer's disease patients: CSF analysis.

J Neural Transm (Vienna) 2012 Jul 14;119(7):763-9. Epub 2012 Mar 14.

Department of Neuroscience, University of Rome Tor Vergata, 1 Montpellier Street, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-012-0778-yDOI Listing
July 2012

Hippocampus versus entorhinal cortex decoupling by an NR2 subunit-specific block of NMDA receptors in a rat in vitro model of temporal lobe epilepsy.

Epilepsia 2012 May 23;53(5):e80-4. Epub 2012 Feb 23.

Foundation Santa Lucia IRCCS, Laboratory of Experimental Neurology, Via del Fosso di Fiorano 64, Rome, Italy.

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http://dx.doi.org/10.1111/j.1528-1167.2012.03420.xDOI Listing
May 2012

Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition.

Neurobiol Dis 2012 Apr 28;46(1):225-33. Epub 2012 Jan 28.

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS Hospital at the European Center for Brain Research, Rome, Italy.

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http://dx.doi.org/10.1016/j.nbd.2012.01.011DOI Listing
April 2012

The distributions of "new" and "old" Alu sequences in the human genome: the solution of a "mystery".

Mol Biol Evol 2012 Jan 5;29(1):421-7. Epub 2011 Nov 5.

Laboratory of Cellular and Developmental Biology, Stazione Zoologica Anton Dohrn, Naples, Italy.

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http://dx.doi.org/10.1093/molbev/msr242DOI Listing
January 2012

Subclinical autonomic dysfunction in spinobulbar muscular atrophy (Kennedy disease).

Muscle Nerve 2011 Nov;44(5):737-40

Department of Neuroscience, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1002/mus.22159DOI Listing
November 2011

Isochores and the regulation of gene expression in the human genome.

Genome Biol Evol 2011 ;3:1080-9

Bioinformatics and Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.

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http://dx.doi.org/10.1093/gbe/evr017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227402PMC
January 2012

Genetic variants of the NMDA receptor influence cortical excitability and plasticity in humans.

J Neurophysiol 2011 Oct 13;106(4):1637-43. Epub 2011 Jul 13.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1152/jn.00318.2011DOI Listing
October 2011

L-DOPA: a scapegoat for accelerated neurodegeneration in Parkinson's disease?

Prog Neurobiol 2011 Sep 24;94(4):389-407. Epub 2011 Jun 24.

Department of Physiology and Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd., Auckland 1142, New Zealand.

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http://dx.doi.org/10.1016/j.pneurobio.2011.06.005DOI Listing
September 2011

CSF tau levels influence cortical plasticity in Alzheimer's disease patients.

J Alzheimers Dis 2011 ;26(1):181-6

Dipartimento di Neuroscienze, Policlinico Tor Vergata, Universitá di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.3233/JAD-2011-110116DOI Listing
January 2012

Increased expression of the beta3 subunit of voltage-gated Na+ channels in the spinal cord of the SOD1G93A mouse.

Mol Cell Neurosci 2011 Jun 31;47(2):108-18. Epub 2011 Mar 31.

Molecular Neurobiology Unit, Experimental Neurology, Fondazione Santa Lucia, via del Fosso di Fiorano 64, 00179 Rome, Italy.

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http://dx.doi.org/10.1016/j.mcn.2011.03.005DOI Listing
June 2011

Difficulty diagnosing chronic cryptococcal meningitis in idiopathic CD4+ lymphocytopenia.

Neurol Sci 2011 Jun 8;32(3):519-24. Epub 2011 Mar 8.

Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1007/s10072-011-0496-5DOI Listing
June 2011

Transcranial magnetic stimulation primes the effects of exercise therapy in multiple sclerosis.

J Neurol 2011 Jul 1;258(7):1281-7. Epub 2011 Feb 1.

Dipartimento di Neuroscienze, Clinica Neurologica, Università Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1007/s00415-011-5924-1DOI Listing
July 2011

Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease.

Brain Res Bull 2012 Feb 25;87(2-3):350-8. Epub 2011 Jan 25.

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS Hospital, Rome, Italy.

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http://dx.doi.org/10.1016/j.brainresbull.2011.01.009DOI Listing
February 2012

Altered dopamine modulation of LTD-like plasticity in Alzheimer's disease patients.

Clin Neurophysiol 2011 Apr 13;122(4):703-7. Epub 2010 Nov 13.

Stroke Unit, Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.clinph.2010.10.033DOI Listing
April 2011

Impaired inter-hemispheric facilitatory connectivity in schizophrenia.

Clin Neurophysiol 2011 Mar 22;122(3):512-517. Epub 2010 Sep 22.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy; Centro Europeo per la Ricerca sul Cervello (CERC)/Fondazione Santa Lucia IRCCS, Rome, Italy.

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http://dx.doi.org/10.1016/j.clinph.2010.08.013DOI Listing
March 2011

GC3 of genes can be used as a proxy for isochore base composition: a reply to Elhaik et al.

Mol Biol Evol 2011 Jan 3;28(1):21-3. Epub 2010 Sep 3.

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http://dx.doi.org/10.1093/molbev/msq222DOI Listing
January 2011

Late-onset CMT2 associated with a novel missense mutation in the cytoplasmic domain of the MPZ gene.

Clin Neurol Neurosurg 2010 Nov 25;112(9):798-800. Epub 2010 Aug 25.

Department of Neurology, Hyogo Brain and Heart Centre, Saisho-Ko 520, Himeji City 670-0981, Hyogo Prefecture, Japan.

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http://dx.doi.org/10.1016/j.clineuro.2010.07.020DOI Listing
November 2010

Differential patterns of interhemispheric functional disconnection in mild and advanced multiple sclerosis.

Mult Scler 2010 Nov 11;16(11):1308-16. Epub 2010 Aug 11.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy.

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http://journals.sagepub.com/doi/10.1177/1352458510376957
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http://dx.doi.org/10.1177/1352458510376957DOI Listing
November 2010

Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis.

Brain Behav Immun 2010 Nov 18;24(8):1379-85. Epub 2010 Jul 18.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.bbi.2010.07.241DOI Listing
November 2010

Inverse correlation between VEGF and soluble VEGF receptor 2 in POEMS with AIDP responsive to intravenous immunoglobulin.

Muscle Nerve 2010 Sep;42(3):445-8

Department of Neurosciences, Tor Vergata University of Rome and IRCCS Fondazione Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.1002/mus.21718DOI Listing
September 2010

Stem cells and neurological diseases.

Discov Med 2010 Jun;9(49):546-53

Laboratorio di Neurogenetica, Centro Europeo di Ricerca sul Cervello, Istituto di Ricovero e Cura a Carattere Scientifico, Via del Fosso di Fiorano 64, Santa Lucia, Rome, Italy.

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June 2010

Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA.

Neuropsychopharmacology 2010 Jun 10;35(7):1500-9. Epub 2010 Mar 10.

Dipartimento di Scienze Biomediche, Università degli Studi di Teramo, Teramo, Italy.

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http://dx.doi.org/10.1038/npp.2010.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055456PMC
June 2010

The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis.

Exp Neurol 2010 Jul 29;224(1):92-102. Epub 2010 Mar 29.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.expneurol.2010.03.030DOI Listing
July 2010

Firing properties and functional connectivity of substantia nigra pars compacta neurones recorded with a multi-electrode array in vitro.

J Physiol 2010 May 29;588(Pt 10):1719-35. Epub 2010 Mar 29.

Fondazione Santa Lucia IRCCS - Via del Fosso di Fiorano 64, 00143 Rome, Italy.

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http://dx.doi.org/10.1113/jphysiol.2010.189415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887990PMC
May 2010

A case of PANDAS treated with tetrabenazine and tonsillectomy.

J Child Neurol 2010 May 5;25(5):614-5. Epub 2010 Mar 5.

Santa Lucia Foundation IRCCS Hospital, Department F and Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS at the European Center for Brain Research, Rome, Italy.

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http://jcn.sagepub.com/content/25/5/614.full.pdf
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http://jcn.sagepub.com/cgi/doi/10.1177/0883073809355824
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http://dx.doi.org/10.1177/0883073809355824DOI Listing
May 2010

SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis.

Brain 2010 Feb 28;133(Pt 2):591-8. Epub 2010 Jan 28.

Centro Europeo di Ricerca sul Cervello -Istituto di Ricovero e Cura a Carattere Scientifico Santa Lucia, 64 Via del Fosso di Fiorano, Rome 00143, Italy.

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http://dx.doi.org/10.1093/brain/awp325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822627PMC
February 2010

Effects of caffeine on striatal neurotransmission: focus on cannabinoid CB1 receptors.

Mol Nutr Food Res 2010 Apr;54(4):525-31

Clinica Neurologica, Dipartimento di Neuroscienze, Universitá Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1002/mnfr.200900237DOI Listing
April 2010

The isochore patterns of invertebrate genomes.

BMC Genomics 2009 Nov 18;10:538. Epub 2009 Nov 18.

Stazione Zoologica Anton Dohrn, Naples, Italy.

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http://dx.doi.org/10.1186/1471-2164-10-538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783168PMC
November 2009

Late-onset MNGIE without peripheral neuropathy due to incomplete loss of thymidine phosphorylase activity.

Neuromuscul Disord 2009 Dec 22;19(12):837-40. Epub 2009 Oct 22.

Department of Neurosciences, University of Rome-Tor Vergata and IRCCS-Fondazione S. Lucia, Via Montpellier 1, I-00135 Rome, Italy.

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http://dx.doi.org/10.1016/j.nmd.2009.08.013DOI Listing
December 2009

Distribution of DNA methylation, CpGs, and CpG islands in human isochores.

Genomics 2010 Jan 1;95(1):25-8. Epub 2009 Oct 1.

Laboratory of Molecular Evolution, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy.

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http://dx.doi.org/10.1016/j.ygeno.2009.09.006DOI Listing
January 2010

Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis.

Neurol Sci 2009 Dec 19;30(6):531-4. Epub 2009 Sep 19.

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1007/s10072-009-0136-5DOI Listing
December 2009

The use of repetitive transcranial magnetic stimulation (rTMS) for the treatment of spasticity.

Prog Brain Res 2009 ;175:429-39

Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S007961230917528
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http://dx.doi.org/10.1016/S0079-6123(09)17528-3DOI Listing
October 2009