Giorgia Federico

Giorgia Federico

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Giorgia Federico

Giorgia Federico

Publications by authors named "Giorgia Federico"

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Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology.

J Med Chem 2020 May 28;63(9):4506-4516. Epub 2020 Apr 28.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II", 80131 Napoli, Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.9b01336DOI Listing
May 2020

RET Gene Fusions in Malignancies of the Thyroid and Other Tissues.

Genes (Basel) 2020 Apr 15;11(4). Epub 2020 Apr 15.

Department of Molecular Medicine and Medical Biotechnology, University of Naples "Federico II", 80131 Naples, Italy.

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http://dx.doi.org/10.3390/genes11040424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230609PMC
April 2020

Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.

Mol Cell Endocrinol 2018 01 23;460:24-35. Epub 2017 Jun 23.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita' Federico II c/o Istituto di Endocrinologia e Oncologia Sperimentale, CNR, Via S Pansini 5, 80131 Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2017.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741508PMC
January 2018

Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase.

PLoS One 2015 5;10(6):e0128364. Epub 2015 Jun 5.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II", Naples, Italy; Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, Naples, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128364PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457528PMC
March 2016

NCOA4 Deficiency Impairs Systemic Iron Homeostasis.

Cell Rep 2016 Jan 14;14(3):411-421. Epub 2016 Jan 14.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, and Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche, 80131 Napoli, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.065DOI Listing
January 2016

Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology.

Angew Chem Int Ed Engl 2015 Jul 30;54(30):8717-21. Epub 2015 Jun 30.

Medicinal Chemistry Division, Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, 1703 E. Mabel, Tucson, AZ 85721 (USA).

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http://doi.wiley.com/10.1002/anie.201501104
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http://dx.doi.org/10.1002/anie.201501104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535927PMC
July 2015