Gina E Sosinsky

Gina E Sosinsky

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Gina E Sosinsky

Gina E Sosinsky

Publications by authors named "Gina E Sosinsky"

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34Publications

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Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1.

PLoS One 2016 9;11(6):e0157073. Epub 2016 Jun 9.

Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157073PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900556PMC
July 2017

Pannexin2 oligomers localize in the membranes of endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane.

Front Cell Neurosci 2014 2;8:468. Epub 2015 Feb 2.

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California San Diego, La Jolla, CA, USA ; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fncel.2014.00468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313697PMC
February 2015

Atomic force microscopy shows connexin26 hemichannel clustering in purified membrane fragments.

Biochemistry 2014 Dec 17;53(47):7407-14. Epub 2014 Nov 17.

Department of Bioengineering, ‡National Center for Microscopy and Imaging Research, §Department of Aerospace and Mechanical Engineering, ∥Department of Neurosciences, and ⊥Materials Science Program, University of California San Diego , 9500 Gillman Drive, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/bi501265pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255643PMC
December 2014

Analysis of trafficking, stability and function of human connexin 26 gap junction channels with deafness-causing mutations in the fourth transmembrane helix.

PLoS One 2013 15;8(8):e70916. Epub 2013 Aug 15.

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California San Diego, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070916PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744544PMC
September 2014

A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations.

Front Pharmacol 2013 6;4. Epub 2013 Feb 6.

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fphar.2013.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565217PMC
February 2013

Picking faces out of a crowd: genetic labels for identification of proteins in correlated light and electron microscopy imaging.

Methods Cell Biol 2012 ;111:139-55

National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093-0608, USA.

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https://linkinghub.elsevier.com/retrieve/pii/B97801241602620
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http://dx.doi.org/10.1016/B978-0-12-416026-2.00008-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532940PMC
December 2012

Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.

Am J Physiol Heart Circ Physiol 2012 Nov 14;303(10):H1208-18. Epub 2012 Sep 14.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1152/ajpheart.00251.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517637PMC
November 2012

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy.

Nat Biotechnol 2012 Nov 21;30(11):1143-8. Epub 2012 Oct 21.

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699407PMC
http://dx.doi.org/10.1038/nbt.2375DOI Listing
November 2012

Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly.

Nature 2012 May 2;486(7401):113-7. Epub 2012 May 2.

Institute of Neurobiology, State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.

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http://dx.doi.org/10.1038/nature10958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599787PMC
May 2012

Pannexin channels are not gap junction hemichannels.

Channels (Austin) 2011 May-Jun;5(3):193-7. Epub 2011 May 1.

National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704572PMC
http://dx.doi.org/10.4161/chan.5.3.15765DOI Listing
October 2011

Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.

J Mol Biol 2011 Jan 20;405(3):724-35. Epub 2010 Nov 20.

Department of Biophysics, Faculty of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan.

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http://dx.doi.org/10.1016/j.jmb.2010.10.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026138PMC
January 2011

Trafficking and recycling of the connexin43 gap junction protein during mitosis.

Traffic 2010 Nov 10;11(11):1471-86. Epub 2010 Sep 10.

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1111/j.1600-0854.2010.01109.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272544PMC
November 2010

Dimensionality Reduction on Multi-Dimensional Transfer Functions for Multi-Channel Volume Data Sets.

Inf Vis 2010 Sep;9(3):167-180

Department of Computer Science and Engineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, USA.

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http://dx.doi.org/10.1057/ivs.2010.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153355PMC
September 2010

Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other.

J Biol Chem 2010 Aug 1;285(32):24420-31. Epub 2010 Jun 1.

National Center for Microscopy and Imaging Research, University of California San Diego, La Jolla, California 92093-0608, USA.

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http://dx.doi.org/10.1074/jbc.M110.115444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915678PMC
August 2010

Analysis of four connexin26 mutant gap junctions and hemichannels reveals variations in hexamer stability.

Biophys J 2010 May;98(9):1809-19

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1016/j.bpj.2010.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862186PMC
May 2010

Multi-Channel Transfer Function with Dimensionality Reduction.

Proc SPIE Int Soc Opt Eng 2010 Jan;7530:75300A

Department of Computer Science and Engineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, USA.

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http://proceedings.spiedigitallibrary.org/proceeding.aspx?do
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http://dx.doi.org/10.1117/12.839526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891081PMC
January 2010

The combination of chemical fixation procedures with high pressure freezing and freeze substitution preserves highly labile tissue ultrastructure for electron tomography applications.

J Struct Biol 2008 Mar 14;161(3):359-71. Epub 2007 Sep 14.

National Center for Microscopy and Imaging Research, Department of Neurosciences, University of California, San Diego, 1070 Basic Science Building MC 0608, 9500 Gilman Drive, La Jolla, CA 92093-0608, USA.

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http://dx.doi.org/10.1016/j.jsb.2007.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2459253PMC
March 2008

Visualizing flock house virus infection in Drosophila cells with correlated fluorescence and electron microscopy.

J Struct Biol 2008 Mar 19;161(3):439-46. Epub 2007 Sep 19.

Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.jsb.2007.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408891PMC
March 2008

Electron tomographic analysis of cytoskeletal cross-bridges in the paranodal region of the node of Ranvier in peripheral nerves.

J Struct Biol 2008 Mar 22;161(3):469-80. Epub 2007 Oct 22.

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, 9500 Gilman Drive, La jolla, CA 92093-0608, USA.

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http://dx.doi.org/10.1016/j.jsb.2007.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346545PMC
March 2008

The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies.

Biochem J 2007 Dec;408(3):375-85

National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, La Jolla, CA 92093-0608, USA.

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http://dx.doi.org/10.1042/BJ20070550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267357PMC
December 2007

Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule.

Proc Natl Acad Sci U S A 2007 Jun 5;104(24):10034-9. Epub 2007 Jun 5.

Department of Biophysics, Faculty of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan.

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http://dx.doi.org/10.1073/pnas.0703704104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1886001PMC
June 2007

Markers for correlated light and electron microscopy.

Methods Cell Biol 2007 ;79:575-91

National Center for Microscopy and Imaging Research and Center for Research in Biological Systems, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1016/S0091-679X(06)79023-9DOI Listing
April 2007

Aminosulfonate modulated pH-induced conformational changes in connexin26 hemichannels.

J Biol Chem 2007 Mar 16;282(12):8895-904. Epub 2007 Jan 16.

BioTechnological Center, University of Technology Dresden, Tatzberg 47-51, 01307 Dresden, Germany.

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http://dx.doi.org/10.1074/jbc.M609317200DOI Listing
March 2007

Development of a model for microphysiological simulations: small nodes of ranvier from peripheral nerves of mice reconstructed by electron tomography.

Neuroinformatics 2005 ;3(2):133-62

National Center for Microscopy and Imaging Research, Department of Neurosciences and the Center for Research on Biological Systems, University of California, San Diego, CA, USA.

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https://papers.cnl.salk.edu/PDFs/Development%20of%20a%20Mode
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http://link.springer.com/10.1385/NI:3:2:133
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http://dx.doi.org/10.1385/NI:3:2:133DOI Listing
September 2005

Structural organization of gap junction channels.

Biochim Biophys Acta 2005 Jun 19;1711(2):99-125. Epub 2005 Apr 19.

National Center for Microscopy and Imaging Research, Department of Neurosciences, University of California San Diego, La Jolla, CA 92093-0608, USA.

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http://dx.doi.org/10.1016/j.bbamem.2005.04.001DOI Listing
June 2005

Tetracysteine genetic tags complexed with biarsenical ligands as a tool for investigating gap junction structure and dynamics.

Cell Commun Adhes 2003 Jul-Dec;10(4-6):181-6

National Center for Microscopy and Imaging Research, Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.

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November 2004

Conformational changes in surface structures of isolated connexin 26 gap junctions.

EMBO J 2002 Jul;21(14):3598-607

Max Planck Institute of Molecular Cell Biology and Genetics and BIOTEC, Technical University Dresden, Dresden, Germany.

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http://dx.doi.org/10.1093/emboj/cdf365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126111PMC
July 2002

Multicolor and electron microscopic imaging of connexin trafficking.

Science 2002 Apr;296(5567):503-7

National Center for Microscopy and Imaging Research, Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1126/science.1068793DOI Listing
April 2002

Isolation and characterization of gap junctions from tissue culture cells.

J Mol Biol 2002 Jan;315(4):587-600

National Center for Microscopy and Imaging Research, Department of Neurosciences, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1006/jmbi.2001.5262DOI Listing
January 2002