Gilles J Guillemin

Gilles J Guillemin

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Gilles J Guillemin

Gilles J Guillemin

Publications by authors named "Gilles J Guillemin"

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Fungal-contaminated grass and well water and sporadic amyotrophic lateral sclerosis.

Neural Regen Res 2019 Sep;14(9):1490-1493

Neuroinflammation Group, Department of Biological Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.4103/1673-5374.255959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557101PMC
September 2019

Microbiota Alterations in Alzheimer's Disease: Involvement of the Kynurenine Pathway and Inflammation.

Neurotox Res 2019 Aug 14;36(2):424-436. Epub 2019 May 14.

Neuroinflammation Group, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s12640-019-00057-3DOI Listing
August 2019

Dendritic spines: Revisiting the physiological role.

Prog Neuropsychopharmacol Biol Psychiatry 2019 06 15;92:161-193. Epub 2019 Jan 15.

College of Pharmacy and Nutrition, University of Saskatchewan, 107, Wiggins Road, Saskatoon, SK S7N 5C9, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02785846183060
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http://dx.doi.org/10.1016/j.pnpbp.2019.01.005DOI Listing
June 2019

Memantine Is Protective against Cytotoxicity Caused by Lead and Quinolinic Acid in Cultured Rat Embryonic Hippocampal Cells.

Chem Res Toxicol 2019 Jun 15;32(6):1134-1143. Epub 2019 Apr 15.

Neuroinflammation Group, Faculty of Medicine and Health Sciences , Macquarie University , Macquarie Park , New South Wales 2109 , Australia.

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http://dx.doi.org/10.1021/acs.chemrestox.8b00421DOI Listing
June 2019

Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status.

Int J Tryptophan Res 2019 19;12:1178646919852996. Epub 2019 Jun 19.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1177/1178646919852996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585246PMC
June 2019

Fungal Neurotoxins and Sporadic Amyotrophic Lateral Sclerosis.

Neurotox Res 2019 May 5;35(4):969-980. Epub 2018 Dec 5.

Neuroinflammation Group, Department of Biological Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/s12640-018-9980-5DOI Listing
May 2019

Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos.

Commun Biol 2019 23;2:198. Epub 2019 May 23.

1Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, NSW Australia.

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http://dx.doi.org/10.1038/s42003-019-0444-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533270PMC
May 2019

Low Molecular Weight Sulfated Chitosan: Neuroprotective Effect on Rotenone-Induced In Vitro Parkinson's Disease.

Neurotox Res 2019 Apr 13;35(3):505-515. Epub 2018 Nov 13.

Neuropharmacology Group, MND and Neurodegenerative Diseases Research Centre, Australian School of Advanced Medicine, Macquarie University, Balaclava Road, North Ryde, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s12640-018-9978-zDOI Listing
April 2019

Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.

Neurotox Res 2019 Apr 21;35(3):530-541. Epub 2019 Jan 21.

Neuroinflammation Group, Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences (FMHS), Macquarie University, 2, Technology Place, North Ryde, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s12640-019-9997-4DOI Listing
April 2019

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau.

Neurobiol Aging 2019 Apr 1;80:11-20. Epub 2019 Apr 1.

Department of Biomedical Sciences, Neuroinflammation Group, Centre for Motor Neuron Disease Research, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.03.015DOI Listing
April 2019

Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons.

Neurotox Res 2019 Feb 28;35(2):281-290. Epub 2018 Sep 28.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/s12640-018-9945-8DOI Listing
February 2019

Time-dependent effect of oligomeric amyloid-β (1-42)-induced hippocampal neurodegeneration in rat model of Alzheimer's disease.

Neurol Res 2019 Feb 19;41(2):139-150. Epub 2018 Nov 19.

a Molecular Gerontology Laboratory, Department of Biochemistry , School of Life Sciences, Bharathidasan University , Tiruchirappalli , India.

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http://dx.doi.org/10.1080/01616412.2018.1544745DOI Listing
February 2019

Protective Effects of Myxobacterial Extracts on Hydrogen Peroxide-induced Toxicity on Human Primary Astrocytes.

Neuroscience 2019 02 26;399:1-11. Epub 2018 Nov 26.

NeuroinflammationGroup, Faculty of Medicine and Health Sciences, Macquarie University, NSW, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03064522183077
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http://dx.doi.org/10.1016/j.neuroscience.2018.11.033DOI Listing
February 2019

Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases.

Oxid Med Cell Longev 2017;2017:5048432. Epub 2017 Apr 26.

Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, Tamil Nadu, India.

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http://dx.doi.org/10.1155/2017/5048432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424479PMC
January 2019

Antioxidant therapies in attention deficit hyperactivity disorder.

Front Biosci (Landmark Ed) 2019 01 1;24:313-333. Epub 2019 Jan 1.

Department of Biology, College of Sciences, Shiraz Branch, Islamic Azad University, Shiraz, Iran.

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January 2019

Human Tick-Borne Diseases in Australia.

Front Cell Infect Microbiol 2019 28;9. Epub 2019 Jan 28.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fcimb.2019.00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360175PMC
January 2019

Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.

Biochem Pharmacol 2018 12 25;158:60-72. Epub 2018 Aug 25.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952183036
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http://dx.doi.org/10.1016/j.bcp.2018.08.038DOI Listing
December 2018

Microorganisms' Footprint in Neurodegenerative Diseases.

Front Cell Neurosci 2018 4;12:466. Epub 2018 Dec 4.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fncel.2018.00466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288487PMC
December 2018

Telmisartan Ameliorates Astroglial and Dopaminergic Functions in a Mouse Model of Chronic Parkinsonism.

Neurotox Res 2018 Oct 13;34(3):597-612. Epub 2018 Jul 13.

Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Sri Shivarathreeshwara Nagar, Mysuru, Karnataka, 570015, India.

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http://dx.doi.org/10.1007/s12640-018-9921-3DOI Listing
October 2018

HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau.

J Neuroimmunol 2018 Jun 18;319:13-18. Epub 2018 Mar 18.

Department of Medicine, University of California at San Diego, La Jolla, CA, United States; Department of Psychiatry, University of California at San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918423PMC
June 2018

Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis.

Inflamm Bowel Dis 2018 06;24(7):1471-1480

Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago Medicine, Chicago, IL, United States.

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http://dx.doi.org/10.1093/ibd/izy103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196764PMC
June 2018

Myxobacterial natural products: An under-valued source of products for drug discovery for neurological disorders.

Neurotoxicology 2018 05 2;66:195-203. Epub 2018 Mar 2.

Neuropharmacology Group, Faculty of Medicine and Health Sciences, Macquarie University, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2018.02.017DOI Listing
May 2018

Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease.

J Alzheimers Dis 2017 ;60(s1):S209-S220

Neuroinflammation group, Faculty of Medicine and Health Sciences, Deb Bailey MND Research Laboratory, Macquarie University, NSW, Australia.

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http://dx.doi.org/10.3233/JAD-161103DOI Listing
April 2018

Detection of the suspected neurotoxin β-methylamino-l-alanine (BMAA) in cyanobacterial blooms from multiple water bodies in Eastern Australia.

Harmful Algae 2018 04 27;74:10-18. Epub 2018 Mar 27.

School of Life Sciences, University of Technology Sydney, NSW, 2007, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hal.2018.03.004DOI Listing
April 2018

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes.

Free Radic Biol Med 2018 02 2;115:371-382. Epub 2017 Dec 2.

Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica, Universidade Federal de Santa Catarina, Campus Universitário, Córrego Grande, Florianópolis, SC 88040-900, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.11.022DOI Listing
February 2018

BMAA and Neurodegenerative Illness.

Neurotox Res 2018 Jan 24;33(1):178-183. Epub 2017 May 24.

Macquarie University, MND Research Centre, FMHS, 2 Technology Place, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s12640-017-9753-6DOI Listing
January 2018

Neurotoxicity of the Cyanotoxin BMAA Through Axonal Degeneration and Intercellular Spreading.

Neurotox Res 2018 Jan 25;33(1):62-75. Epub 2017 Aug 25.

Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Neuroscience Paris Seine, Adaptation Biologique et vieillissement, F-75005, Paris, France.

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http://dx.doi.org/10.1007/s12640-017-9790-1DOI Listing
January 2018

Detection of the Cyanotoxins L-BMAA Uptake and Accumulation in Primary Neurons and Astrocytes.

Neurotox Res 2018 Jan 30;33(1):55-61. Epub 2017 Aug 30.

Macquarie University Centre for MND Research, Department of Biological Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s12640-017-9787-9DOI Listing
January 2018

Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease.

Front Biosci (Schol Ed) 2018 01 1;10:262-275. Epub 2018 Jan 1.

Neuroinflammation group, Faculty of Medicine and Health Sciences, Macquarie University, NSW, Australia.

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January 2018

Major Developments in the Design of Inhibitors along the Kynurenine Pathway.

Curr Med Chem 2017 ;24(23):2471-2495

Department of Biomedical Research, Faculty of Medicine and Health Science, Macquarie University, 2 Technology Place, Sydney. Australia.

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http://dx.doi.org/10.2174/0929867324666170502123114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748880PMC
September 2017

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

Hum Mol Genet 2017 09;26(17):3452

Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Macquarie University, NSW 2109, Australia.

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http://dx.doi.org/10.1093/hmg/ddx268DOI Listing
September 2017

Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease.

Prog Neurobiol 2017 Aug 9;155:76-95. Epub 2016 Apr 9.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia; Applied Neurosciences Program, Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2015.12.009DOI Listing
August 2017

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

N Engl J Med 2017 08;377(6):544-552

From the Divisions of Developmental and Stem Cell Biology (H.S., A.E., M.R., E.M.M.A.M., R.W., J.M., J.O.S., E.I., K.S., J.H., K.K., G.C., D.B.S., S.L.D.), Vascular Biology (G.J.M., R.S.), and Molecular, Structural, and Computational Biology (D.T.H., J.W.K.H., E.G.), Victor Chang Cardiac Research Institute, the Faculties of Medicine and Science, University of New South Wales (H.S., A.E., J.O.S., E.I., D.T.H., G.J.M., J.W.K.H., K.K., R.S., E.G., G.C., D.B.S., S.L.D.), Liverpool Hospital, Department of Clinical Genetics (A.E., A.C.), the Department of Clinical Genetics (A.E., J.S., F.C., D.O.S.) and the Heart Centre for Children (D.S.W.), Children's Hospital at Westmead, the Discipline of Genetic Medicine (A.E., J.S., F.C., D.O.S.) and the Medical School (D.S.W.), University of Sydney, and the Faculty of Medicine and Health Sciences, Macquarie University (C.K.L., G.J.G.) - all in Sydney, the School of Biological Sciences, University of Adelaide, Adelaide, SA (J.N.H., P.Q.T.), and the Institute of Health and Biomedical Innovation, Queensland University of Technology (A.M.M.-L., P.J.L., M.A.B., E.L.D.), the Translational Research Institute (A.M.M.-L., P.J.L., M.A.B., E.L.D.), the Department of Endocrinology, Royal Brisbane and Women's Hospital (E.L.D.), and the University of Queensland School of Medicine (E.L.D.), Brisbane - all in Australia; and Spectrum Health Medical Group, Medical Genetics, Grand Rapids, MI (P.R.M.).

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http://dx.doi.org/10.1056/NEJMoa1616361DOI Listing
August 2017

Chronic mild stress augments MPTP induced neurotoxicity in a murine model of Parkinson's disease.

Physiol Behav 2017 05 6;173:132-143. Epub 2017 Feb 6.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia; Neuropharmacology Group, ASAM, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.physbeh.2017.01.046DOI Listing
May 2017

Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington's Disease.

Oxid Med Cell Longev 2017 12;2017:3279061. Epub 2017 Jan 12.

Laboratory of Stem Cells and Neuroregeneration, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India; UGC-Faculty Recharge Program (UGC-FRP), University Grant Commission, New Delhi, India.

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http://dx.doi.org/10.1155/2017/3279061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266860PMC
March 2017

Bcl11b-A Critical Neurodevelopmental Transcription Factor-Roles in Health and Disease.

Front Cell Neurosci 2017 29;11:89. Epub 2017 Mar 29.

Applied Neurosciences Program, Peter Duncan Neurosciences Research Unit, St. Vincent's Centre for Applied Medical ResearchSydney, NSW, Australia.

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http://dx.doi.org/10.3389/fncel.2017.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372781PMC
March 2017

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression.

Sci Rep 2017 02 3;7:41473. Epub 2017 Feb 3.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, NSW 2109, Australia.

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http://dx.doi.org/10.1038/srep41473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290739PMC
February 2017

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases.

Neuropharmacology 2017 Jan 16;112(Pt B):373-388. Epub 2016 Mar 16.

Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, 405 Liverpool Street, Darlinghurst, Sydney, NSW, 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, Australia; Department of Neurology, St Vincent's Hospital, Level 4 Xavier Building, Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2016.03.024DOI Listing
January 2017

Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis.

Neuropharmacology 2017 Jan 3;112(Pt B):346-364. Epub 2016 Jun 3.

Macquarie University, Faculty of Medicine and Health Sciences, Department of Biomedical Sciences, Sydney, Australia; Peter Duncan, Neurosciences Unit, St Vincent's Centre for Applied Medical Research, Sydney, Australia.

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http://dx.doi.org/10.1016/j.neuropharm.2016.05.011DOI Listing
January 2017

Consumption of fig fruits grown in Oman can improve memory, anxiety, and learning skills in a transgenic mice model of Alzheimer's disease.

Nutr Neurosci 2016 Dec 2;19(10):475-483. Epub 2016 Mar 2.

e Neuropharmacology Group, MND and Neurodegenerative diseases Research Centre, Macquarie University , NSW , Australia.

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http://dx.doi.org/10.1179/1476830514Y.0000000131DOI Listing
December 2016

Characterization of the Kynurenine Pathway in CD8 Human Primary Monocyte-Derived Dendritic Cells.

Neurotox Res 2016 11 10;30(4):620-632. Epub 2016 Aug 10.

Neuropharmacology Group, MND and Neurodegenerative Diseases Research Centre, Macquarie University, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s12640-016-9657-xDOI Listing
November 2016

Interference of α-Synuclein Uptake by Monomeric β-Amyloid1-40 and Potential Core Acting Site of the Interference.

Neurotox Res 2016 10 30;30(3):479-85. Epub 2016 Jun 30.

Department of Surgery and Centre for Neuroscience, School of Medicine, Flinders University, Bedford Park, SA, 5042, Australia.

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http://dx.doi.org/10.1007/s12640-016-9644-2DOI Listing
October 2016

Vanillin Attenuated Behavioural Impairments, Neurochemical Deficts, Oxidative Stress and Apoptosis Against Rotenone Induced Rat Model of Parkinson's Disease.

Neurochem Res 2016 Aug 2;41(8):1899-910. Epub 2016 Apr 2.

Neuropharmacology Group, MND and Neurodegenerative Diseases Research Centre, Australian School of Advanced Medicine, Macquarie University, Balaclava Road, North Ryde, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s11064-016-1901-5DOI Listing
August 2016

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis.

Front Immunol 2016 4;7:246. Epub 2016 Aug 4.

Applied Neurosciences Program, Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Sydney, NSW, Australia; Faculty of Medicine, St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia; Department of Neurology, St Vincent's Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2016.00246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972824PMC
August 2016

Keratin 14 Expression in Epithelial Progenitor Cells of the Developing Human Cornea.

Stem Cells Dev 2016 05 12;25(9):699-711. Epub 2016 Apr 12.

1 Ocular Diseases Research Group, School of Medical Sciences, University of New South Wales , Sydney, Australia .

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http://dx.doi.org/10.1089/scd.2016.0039DOI Listing
May 2016

Lycopene Pretreatment Ameliorates Acute Ethanol Induced NAD(+) Depletion in Human Astroglial Cells.

Oxid Med Cell Longev 2015 14;2015:741612. Epub 2015 May 14.

Australasian Research Institute, Sydney Adventist Hospital, Sydney, NSW 2076, Australia ; Department of Pharmacology, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia ; Sydney Adventist Hospital Clinical School, University of Sydney, Sydney, NSW 2076, Australia.

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http://dx.doi.org/10.1155/2015/741612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446500PMC
April 2016

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease.

PLoS One 2015 26;10(6):e0131389. Epub 2015 Jun 26.

Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW, Sydney, Australia; Department of Neurology, St Vincent's Hospital, Sydney, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131389PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482723PMC
April 2016

Editorial: Glial Cells: Managers of Neuro-Immunity.

Front Cell Neurosci 2016 23;10:60. Epub 2016 Mar 23.

U.S. Centers for Disease Control and Prevention Atlanta, GA, USA.

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http://dx.doi.org/10.3389/fncel.2016.00060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803723PMC
April 2016

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

Nat Commun 2016 Apr 15;7:11253. Epub 2016 Apr 15.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales 2109, Australia.

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http://dx.doi.org/10.1038/ncomms11253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835537PMC
April 2016

Central kynurenine pathway shift with age in women.

J Neurochem 2016 Mar 20;136(5):995-1003. Epub 2016 Jan 20.

Australasian Research Institute, Sydney Adventist Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/jnc.13496DOI Listing
March 2016

Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.

J Cell Sci 2016 Mar 29;129(6):1198-209. Epub 2016 Jan 29.

Inflammation and Infection Research Centre, School of Medical Sciences, Department of Pathology, UNSW, Sydney, New South Wales 2052, Australia

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http://dx.doi.org/10.1242/jcs.182006DOI Listing
March 2016

Bcl11b: A New Piece to the Complex Puzzle of Amyotrophic Lateral Sclerosis Neuropathogenesis?

Neurotox Res 2016 Feb 12;29(2):201-7. Epub 2015 Nov 12.

Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Sydney, Australia.

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http://dx.doi.org/10.1007/s12640-015-9573-5DOI Listing
February 2016

Kynurenine-3-monooxygenase: a review of structure, mechanism, and inhibitors.

Drug Discov Today 2016 Feb 14;21(2):315-24. Epub 2015 Nov 14.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1016/j.drudis.2015.11.001DOI Listing
February 2016

Understanding the role of the kynurenine pathway in human breast cancer immunobiology.

Oncotarget 2016 Feb;7(6):6506-20

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.18632/oncotarget.6467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872729PMC
February 2016

Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: Possible role in cerebral malaria.

Cytokine 2016 Feb 11;78:79-86. Epub 2015 Dec 11.

Molecular Immunopathology Unit, Discipline of Pathology, School of Medical Sciences and Bosch Institute, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.11.024DOI Listing
February 2016

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes.

Oncotarget 2016 Feb;7(7):7426-40

MND and Neurodegenerative Diseases Research Group, Australian School of Advanced Medicine (ASAM), Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.18632/oncotarget.6863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884929PMC
February 2016

Genetic basis of hindlimb loss in a naturally occurring vertebrate model.

Biol Open 2016 Feb 18;5(3):359-66. Epub 2016 Feb 18.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales 2109, Australia Department of Anatomy & Histology, School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia

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http://dx.doi.org/10.1242/bio.016295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810746PMC
February 2016

Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers.

PLoS One 2015 16;10(4):e0122046. Epub 2015 Apr 16.

Macquarie University, Faculty of Medicine, Neuroinflammation group, Sydney, New South Wales, Australia; Applied Neurosciences Program, Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Darlinghurst, New South Wales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122046PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400104PMC
January 2016

Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation.

Front Cell Neurosci 2015 12;9:437. Epub 2015 Nov 12.

Menzies Health Institute Queensland, Griffith University Gold Coast, QLD, Australia.

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http://dx.doi.org/10.3389/fncel.2015.00437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700780PMC
January 2016

An effective, low-cost method for achieving and maintaining hypoxia during cell culture studies.

Biotechniques 2015 Oct 1;59(4):223-4, 226, 228-9. Epub 2015 Oct 1.

Molecular Immunopathology Unit, Discipline of Pathology, School of Medical Sciences and Bosch Institute, Sydney Medical School, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.2144/000114341DOI Listing
October 2015

Involvement of the kynurenine pathway in human glioma pathophysiology.

PLoS One 2014 21;9(11):e112945. Epub 2014 Nov 21.

MND and Neurodegenerative Diseases Research Centre, Australian School of Advanced Medicine, Macquarie University, Sydney, NSW, Australia; St Vincent's Centre for Applied Medical Research, Sydney, NSW, Australia; Department of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112945PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240539PMC
July 2015

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

Hum Mol Genet 2015 Jul 9;24(13):3830-46. Epub 2015 Apr 9.

Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Macquarie University, NSW 2109, Australia and Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Victoria 3086, Australia

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http://dx.doi.org/10.1093/hmg/ddv126DOI Listing
July 2015

Food and your mood: nutritional psychiatry.

Lancet Psychiatry 2015 Jul 30;2(7):e19. Epub 2015 Jun 30.

Neuropharmacology group, Motor Neurone Disease and Neurodegenerative Diseases Research Centre, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/S2215-0366(15)00241-2DOI Listing
July 2015

Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes.

J Cell Biochem 2015 Jun;116(6):903-22

Department of Pharmacology, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1002/jcb.25019DOI Listing
June 2015

Global cellular responses to β-methyl-amino-L-alanine (BMAA) by olfactory ensheathing glial cells (OEC).

Toxicon 2015 Jun 19;99:136-45. Epub 2015 Mar 19.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2015.03.009DOI Listing
June 2015

Dietary Supplementation of Walnut Partially Reverses 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Neurodegeneration in a Mouse Model of Parkinson's Disease.

Neurochem Res 2015 Jun 6;40(6):1283-93. Epub 2015 May 6.

Department of Food Science and Nutrition, College of Agricultural and Marine Sciences (CAMS), Sultan Qaboos University, P.O. 34, Al-Khoud, Muscat, 123, Sultanate of Oman,

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http://dx.doi.org/10.1007/s11064-015-1593-2DOI Listing
June 2015

Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation.

Eur J Med Chem 2015 May 3;95:29-34. Epub 2015 Mar 3.

School of Chemistry, University of Sydney, NSW 2006, Australia; Faculty of Health Sciences, University of Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.03.003DOI Listing
May 2015

Differential expression of sirtuins in the aging rat brain.

Front Cell Neurosci 2015 8;9:167. Epub 2015 May 8.

Neuropharmacology Group, MND and Neurodegenerative Diseases Research Centre, Macquarie University North Ryde NSW, Australia.

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http://dx.doi.org/10.3389/fncel.2015.00167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846PMC
May 2015

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.

J Neuroinflammation 2015 May 30;12:110. Epub 2015 May 30.

Australian New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1186/s12974-015-0328-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457980PMC
May 2015

Long-term (15 mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease.

Nutrition 2015 Jan 25;31(1):223-9. Epub 2014 Jun 25.

Neuropharmacology Group, MND and Neurodegenerative diseases Research Centre, Macquarie University, NSW, Australia.

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http://dx.doi.org/10.1016/j.nut.2014.06.004DOI Listing
January 2015

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies.

J Neuroinflammation 2014 Dec 13;11:204. Epub 2014 Dec 13.

Applied Neurosciences Program, Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Sydney, Australia.

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http://dx.doi.org/10.1186/s12974-014-0204-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302518PMC
December 2014

Pomegranate from Oman Alleviates the Brain Oxidative Damage in Transgenic Mouse Model of Alzheimer's disease.

J Tradit Complement Med 2014 Oct;4(4):232-8

Neuropharmacology group, MND and Neurodegenerative diseases Research Centre, Macquarie University, NSW, Australia.

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http://dx.doi.org/10.4103/2225-4110.139107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220500PMC
October 2014

The potential for transition metal-mediated neurodegeneration in amyotrophic lateral sclerosis.

Front Aging Neurosci 2014 23;6:173. Epub 2014 Jul 23.

Australian School of Advanced Medicine, Macquarie University , Sydney, NSW , Australia.

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http://dx.doi.org/10.3389/fnagi.2014.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107949PMC
August 2014

Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton.

Neurol Neuroimmunol Neuroinflamm 2014 Jun 22;1(1):e12. Epub 2014 May 22.

Neuroimmunology Group (R.C.D., E.M.T., V.M., R.-Y.A.K., N.S., K. Pathmanandavel, S.R., F.B.), Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children's Hospital at Westmead, Sydney Medical School, University of Sydney, Westmead, Australia; Institute for Immunology and Allergy Research (D.R.B.), Westmead Millenium Institute for Medical Research, University of Sydney, Westmead, Australia; Clinical Immunology (L.A.W.), Royal Prince Alfred Hospital, Sydney Medical School Immunology & Infectious Diseases, University of Sydney, Camperdown, Australia; Department of Radiology (K. Prelog), the Children's Hospital at Westmead, Australia; Department of Paediatric Neurology (D.R.C.), Women's and Children's Hospital, North Adelaide, Australia; Neuroinflammation Group (G.J.G., C.K.L.), MND and Neurodegenerative Diseases Research Centre, Macquarie University, Australian School of Advanced Medicine, North Ryde, Australia; and Neuroinflammation Group (E.K.M.), Brain and Mind Research Institute, University of Sydney, Camperdown, Australia.

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http://dx.doi.org/10.1212/NXI.0000000000000012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202678PMC
June 2014