Gilles Chiocchia

Gilles Chiocchia

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Gilles Chiocchia

Publications by authors named "Gilles Chiocchia"

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HLA-B27 alters BMP/TGFβ signalling in , revealing putative pathogenic mechanism for spondyloarthritis.

Ann Rheum Dis 2019 Sep 28. Epub 2019 Sep 28.

Chronic Inflammation & Immune System, UMR 1173 Inserm-University of Versailles Saint-Quentin, Montigny-le-Bretonneux, France

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http://dx.doi.org/10.1136/annrheumdis-2019-215832DOI Listing
September 2019

Tolerogenic XCR1 dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis.

Arthritis Res Ther 2019 Feb 4;21(1):46. Epub 2019 Feb 4.

INSERM U1173, UFR Simone Veil, Versailles-Saint-Quentin University, 2 avenue de la source de la Bièvre, 78190, Montigny le Bretonneux, France.

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http://dx.doi.org/10.1186/s13075-019-1827-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360689PMC
February 2019

Exploring antibody-dependent adaptive immunity against aortic extracellular matrix components in experimental aortic aneurysms.

J Vasc Surg 2018 12 5;68(6S):60S-71S.e3. Epub 2018 Mar 5.

UMR 1148, Inserm Paris 7, Denis Diderot University, Xavier Bichat Hospital, Paris, France.

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http://dx.doi.org/10.1016/j.jvs.2017.11.090DOI Listing
December 2018

Faecal microbiota study reveals specific dysbiosis in spondyloarthritis.

Ann Rheum Dis 2017 Sep 12;76(9):1614-1622. Epub 2017 Jun 12.

Micalis Institute, INRA, AgroParisTech, Université ParisSaclay, Jouy-en-Josas, France.

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http://dx.doi.org/10.1136/annrheumdis-2016-211064DOI Listing
September 2017

A family-based genome-wide association study reveals an association of spondyloarthritis with MAPK14.

Ann Rheum Dis 2017 Jan 26;76(1):310-314. Epub 2016 Jul 26.

Faculty of Health Sciences Simone Veil, University of Versailles Saint-Quentin-en-Yvelines, Montigny-le-Bretonneux, France.

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http://dx.doi.org/10.1136/annrheumdis-2016-209449DOI Listing
January 2017

Whole-genome single nucleotide polymorphism-based linkage analysis in spondyloarthritis multiplex families reveals a new susceptibility locus in 13q13.

Ann Rheum Dis 2016 07 14;75(7):1380-5. Epub 2015 Aug 14.

INSERM U1173, UFR Simone Veil, Versailles-Saint Quentin University, Saint-Quentin en Yvelines, France Université Paris Diderot, Sorbonne Paris Cité, Laboratoire d'Excellence, Paris, France Genetics Division, Ambroise Paré Hospital (AP-HP), Boulogne-Billancourt, France.

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http://dx.doi.org/10.1136/annrheumdis-2015-207720DOI Listing
July 2016

OX40L blockade protects against inflammation-driven fibrosis.

Proc Natl Acad Sci U S A 2016 07 13;113(27):E3901-10. Epub 2016 Jun 13.

INSERM, U1016 UMR8104, Cochin Institute, Paris Descartes University, Sorbonne Paris Cite, 75014 Paris, France; Rheumatology A Department, Cochin Hospital, Paris Descartes University, 75014 Paris, France;

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http://dx.doi.org/10.1073/pnas.1523512113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941508PMC
July 2016

Synergy of chemotherapy and immunotherapy revealed by a genome-scale analysis of murine tuberculosis.

J Antimicrob Chemother 2015 16;70(6):1774-83. Epub 2015 Feb 16.

The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil.

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http://dx.doi.org/10.1093/jac/dkv023DOI Listing
February 2016

What can immunophenotyping of T and dendritic cells teach us about the pathophysiology of ankylosing spondylitis?

Rheumatology (Oxford) 2016 Jan 28;55(1):4-5. Epub 2015 Aug 28.

Faculty of Health Sciences Simone Veil, INSERM U1173, University of Versailles Saint-Quentin-en-Yvelines Montigny-le-Bretonneux, University Paris Diderot, Sorbonne Paris Cité, Laboratoire d'Excellence Inflamex, Paris and Service de Rhumatologie, Ambroise Paré Hospital, Boulogne-Billancourt, France.

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http://dx.doi.org/10.1093/rheumatology/kev299DOI Listing
January 2016

Modulatory role of the anti-apoptotic protein kinase CK2 in the sub-cellular localization of Fas associated death domain protein (FADD).

Biochim Biophys Acta 2015 Nov 5;1853(11 Pt A):2885-96. Epub 2015 Aug 5.

Inserm U1173, Université Versailles-Saint-Quentin, Saint-Quentin-En-Yvelines, France; UFR des Sciences de la Santé, Simone Veil, 78180 Montigny-Le-Bretonneux, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.08.001DOI Listing
November 2015

Eosinophilia predicts poor clinical outcomes in recent-onset arthritis: results from the ESPOIR cohort.

RMD Open 2015 15;1(1):e000070. Epub 2015 Jul 15.

Department of Rheumatology , CHU de la Cavale Blanche, Boulevard Tanguy Prigent , Brest , France ; EA 2216, INSERM ESPRI, ERI29 Université Bretagne Occidentale , Brest , France.

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http://dx.doi.org/10.1136/rmdopen-2015-000070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613150PMC
October 2015

The alternative CD20 transcript variant is not a surrogate marker for resistance to rituximab in patients with rheumatoid arthritis.

Rheumatology (Oxford) 2015 Sep 27;54(9):1744-5. Epub 2015 Jun 27.

Université de Franche Comté, UPRES EA 4266 Agents Pathogènes et Inflammation, Besançon, INSERM, CIC 1431, Centre investigation Clinique Biothérapie, Fédération Hospitalo-Universitaire INCREASE, CHRU, CHRU Besançon, Rhumatologie and Université de Franche Comté, Département Universitaire de Thérapeutique, Besançon, France

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http://dx.doi.org/10.1093/rheumatology/kev210DOI Listing
September 2015

Cytokines and disease.

Mediators Inflamm 2014 14;2014:209041. Epub 2014 Sep 14.

Simone Veil Department of Health Sciences, University Versailles-Saint-Quentin, 78180 Montigny-Le-Bretonneux, France.

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http://www.hindawi.com/journals/mi/2014/209041/
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http://dx.doi.org/10.1155/2014/209041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180395PMC
June 2015

ERAP1 Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis.

Arthritis Rheumatol 2015 Jun;67(6):1525-34

INSERM U1173, Université de Versailles St. Quentin-en-Yvelines, and Laboratoire d'Excellence INFLAMEX, Paris, France and Hôpital Ambroise Paré, AP-HP, Boulogne-Billancourt, France.

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http://dx.doi.org/10.1002/art.39072DOI Listing
June 2015

Revisiting MHC genes in spondyloarthritis.

Curr Rheumatol Rep 2015 Jun;17(6):516

Rheumatology Division, Ambroise Paré Hospital, AP-HP, 9 ave Charles de Gaulle, 92100, Boulogne-Billancourt, France,

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http://link.springer.com/10.1007/s11926-015-0516-1
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http://dx.doi.org/10.1007/s11926-015-0516-1DOI Listing
June 2015

Prevalence of spondyloarthritis in reference to HLA-B27 in the French population: results of the GAZEL cohort.

Ann Rheum Dis 2015 Apr 18;74(4):689-93. Epub 2013 Dec 18.

Institut Cochin, Université Paris Descartes, Paris, France INSERM U1016, Paris, France Rheumatology Division, Ambroise Paré Hospital (AP-HP), Boulogne-Billancourt, France UFR des Sciences de la Santé, Simone Veil, Versailles Saint Quentin en Yvelines University, Montigny-Le-Bretonneux, France.

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http://dx.doi.org/10.1136/annrheumdis-2013-204436DOI Listing
April 2015

Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models.

J Inflamm (Lond) 2015 8;12. Epub 2015 Feb 8.

Rheumatology A department, Cochin Hospital, Paris Descartes University, Sorbonne Paris Cité, 27 rue du Faubourg Saint Jacques, 75014 Paris, France ; Cochin Institut, INSERM U1016, UMR 8104, Team ATIP/AVENIR, Paris Descartes University, Paris, France.

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http://dx.doi.org/10.1186/s12950-015-0056-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327789PMC
February 2015

Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo.

J Autoimmun 2015 Jan 30;56:23-33. Epub 2014 Sep 30.

Institut National de la Santé et de la Recherche Médicale (Inserm), U1148, "Laboratory of Vascular Translational Science", F-75018 Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Faculté de Médecine, Site Xavier Bichat, F-75018 Paris, France; Département Hospitalo-Universitaire DHU "FIRE", F-75018 Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411140013
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http://dx.doi.org/10.1016/j.jaut.2014.09.002DOI Listing
January 2015

Increased production of interleukin-17 over interleukin-10 by treg cells implicates inducible costimulator molecule in experimental spondyloarthritis.

Arthritis Rheumatol 2014 Sep;66(9):2412-22

INSERM U987 and Université de Versailles St.-Quentin-en-Yvelines, Montigny-le-Bretonneux, France, and Université Paris Diderot, Sorbonne Paris Cité, and Laboratoire d'Excellence Inflamex, Paris, France.

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http://dx.doi.org/10.1002/art.38737DOI Listing
September 2014

Animal models of spondyloarthritis: do they faithfully mirror human disease?

Arthritis Rheumatol 2014 Jul;66(7):1689-92

University of Versailles St.-Quentin-en-Yvelines, INSERM U987, Montigny-le-Bretonneux, France, University Paris Diderot, Sorbonne Paris Cité, Paris, France, and Ambroise Paré Hospital, AP-HP, Boulogne-Billancourt, France.

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http://dx.doi.org/10.1002/art.38636DOI Listing
July 2014

Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis.

Arthritis Rheumatol 2014 Apr;66(4):841-51

Université Paris-Descartes, Sorbonne Paris Cité, Laboratoire d'Excellence Inflamex, Institut Cochin, and INSERM U1016, CNRS (UMR 8104), Paris, France.

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http://dx.doi.org/10.1002/art.38318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226235PMC
April 2014

Brief report: the IL23R nonsynonymous polymorphism rs11209026 is associated with radiographic sacroiliitis in spondyloarthritis.

Arthritis Rheum 2013 Oct;65(10):2655-60

Institut Cochin, Université Paris Descartes, CNRS, UMR 8104, and INSERM U1016, Paris, France.

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http://dx.doi.org/10.1002/art.38060DOI Listing
October 2013

Performance of skin ultrasound to measure skin involvement in different animal models of systemic sclerosis.

Ultrasound Med Biol 2013 May 7;39(5):845-52. Epub 2013 Mar 7.

Paris Descartes University, INSERM U1016, Institut Cochin, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2012.12.002DOI Listing
May 2013

Investigating the genetic association between ERAP1 and spondyloarthritis.

Ann Rheum Dis 2013 Apr 15;72(4):608-13. Epub 2012 Aug 15.

Rheumatology Division, Hôpital Ambroise Paré, 9 Avenue Charles de Gaulle, Boulogne 92100, France.

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http://dx.doi.org/10.1136/annrheumdis-2012-201783DOI Listing
April 2013

Human inflammatory dendritic cells induce Th17 cell differentiation.

Immunity 2013 Feb 24;38(2):336-48. Epub 2013 Jan 24.

INSERM U932, 26 rue d'Ulm, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.immuni.2012.10.018DOI Listing
February 2013

Fas-associated death domain protein and adenosine partnership: fad in RA.

Rheumatology (Oxford) 2012 Jun 16;51(6):964-75. Epub 2012 Jan 16.

Département d’Immunologie-Hématologie, Institut Cochin, Inserm U1016, France.

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http://dx.doi.org/10.1093/rheumatology/ker402DOI Listing
June 2012

Association between the IL-1 family gene cluster and spondyloarthritis.

Ann Rheum Dis 2012 Jun 6;71(6):885-90. Epub 2012 Feb 6.

Department of Ophthalmology,Institut Cochin (INSERM U1016, CNRS UMR8104 and Université Paris Descartes, Paris, France.

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http://ard.bmj.com/content/71/6/885.full.pdf
Web Search
http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2011-20043
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http://dx.doi.org/10.1136/annrheumdis-2011-200439DOI Listing
June 2012

Angiogenic biomarkers predict the occurrence of digital ulcers in systemic sclerosis.

Ann Rheum Dis 2012 Mar 15;71(3):394-9. Epub 2011 Nov 15.

Rheumatology A department, Paris Descartes University, Cochin Hospital, APHP, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1136/annrheumdis-2011-200143DOI Listing
March 2012

Proinflammatory Th17 cells are expanded and induced by dendritic cells in spondylarthritis-prone HLA-B27-transgenic rats.

Arthritis Rheum 2012 Jan;64(1):110-20

Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), and INSERM U1016, Paris, France.

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http://dx.doi.org/10.1002/art.33321DOI Listing
January 2012

Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor-derived endothelial cells.

Arthritis Rheum 2011 Nov;63(11):3552-62

Université Paris Descartes and Hôpital Cochin, AP-HP, and INSERM U1016, Cochin Institut, Paris, France.

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http://dx.doi.org/10.1002/art.30536DOI Listing
November 2011

Gene expression profile in the salivary glands of primary Sjögren's syndrome patients before and after treatment with rituximab.

Arthritis Rheum 2010 Aug;62(8):2262-71

Hôpital de la Cavale Blanche, Centre Hospitalier Universitaire Brest, and Hôpital Morvan, Brest, France.

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http://dx.doi.org/10.1002/art.27509DOI Listing
August 2010

No evidence for XMRV association in pediatric idiopathic diseases in France.

Retrovirology 2010 Aug 2;7:63. Epub 2010 Aug 2.

Institut de Génétique Moléculaire de Montpellier UMR 5535 CNRS, 1919 route de Mende, 34293 Montpellier cedex 5, France.

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http://dx.doi.org/10.1186/1742-4690-7-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920251PMC
August 2010

FADD: a regulator of life and death.

Trends Immunol 2010 Jul 25;31(7):260-9. Epub 2010 Jun 25.

Inserm, U1016, Institut Cochin, Département d'Immunologie-Hématologie, Paris, France.

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http://dx.doi.org/10.1016/j.it.2010.05.005DOI Listing
July 2010

Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia.

Arthritis Res Ther 2009 29;11(3):R99. Epub 2009 Jun 29.

Department of Rheumatology, Rouen University Hospital and Inserm 905 & Institut Fédératif de Recherche Multidisciplinaire sur les Peptides 23, Institute for Biomedical Research, University of Rouen, 76031 Rouen Cedex, France.

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http://dx.doi.org/10.1186/ar2744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714155PMC
March 2010

Identification of clusterin domain involved in NF-kappaB pathway regulation.

J Biol Chem 2010 Feb 22;285(7):4273-7. Epub 2009 Dec 22.

Inserm, U567, Institut Cochin, 75014 Paris, France.

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http://dx.doi.org/10.1074/jbc.C109.057133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836031PMC
February 2010

Treatment of collagen-induced arthritis by Natura-alpha via regulation of Th-1/Th-17 responses.

Eur J Immunol 2010 Feb;40(2):460-9

Institut Cochin, Université Paris Descartes CNRS (UMR 8104), Paris, France.

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http://dx.doi.org/10.1002/eji.200939566DOI Listing
February 2010

Chapter 8: Clusterin: A multifacet protein at the crossroad of inflammation and autoimmunity.

Adv Cancer Res 2009 ;104:139-70

EA 4222, University of Paris 13, Bobigny, France.

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http://dx.doi.org/10.1016/S0065-230X(09)04008-1DOI Listing
January 2010

Dramatic efficacy improvement of a DC-based vaccine against AML by CD25 T cell depletion allowing the induction of a long-lasting T cell response.

Cancer Immunol Immunother 2009 Oct 19;58(10):1669-77. Epub 2009 Feb 19.

Département d'Immunologie, Institut Cochin, Institut National de la Santé Et de la Recherche Médicale (INSERM) U 567, Centre National de Recherche Scientifique (CNRS) UMR 8104, Université René Descartes, Paris V, France.

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http://dx.doi.org/10.1007/s00262-009-0678-7DOI Listing
October 2009

Adenosine receptors control a new pathway of Fas-associated death domain protein expression regulation by secretion.

J Biol Chem 2008 Jun 29;283(26):17929-38. Epub 2008 Apr 29.

Inserm, U567, Institut Cochin, Paris, France.

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http://dx.doi.org/10.1074/jbc.M802263200DOI Listing
June 2008

Dendritic cells and interferon-mediated autoimmunity.

Biochimie 2007 Jun-Jul;89(6-7):856-71. Epub 2007 May 5.

Département d'Immunologie, Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France.

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http://dx.doi.org/10.1016/j.biochi.2007.04.013DOI Listing
September 2007

DC-based vaccine loaded with acid-eluted peptides in acute myeloid leukemia: the importance of choosing the best elution method.

Cancer Immunol Immunother 2007 Jan 5;56(1):1-12. Epub 2006 May 5.

Département d'Immunologie, Institut Cochin, Institut National de la Santé Et de la Recherche Médicale (INSERM) U 567, Centre National de Recherche Scientifique (CNRS) UMR 8104, Université René Descartes, Paris V, Paris, France.

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http://link.springer.com/10.1007/s00262-006-0170-6
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http://dx.doi.org/10.1007/s00262-006-0170-6DOI Listing
January 2007

Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome.

Proc Natl Acad Sci U S A 2006 Feb 13;103(8):2770-5. Epub 2006 Feb 13.

Institut Pour la Santé et de la Recherche Médicale E 802 and Service de Rhumatologie, Hôpital de Bicêtre, Assistance Publique-Hôpitaux de Paris, 94275 Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1073/pnas.0510837103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413808PMC
February 2006

Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes.

Eur Cytokine Netw 2005 Dec;16(4):289-92

Institut Cochin, Département d'Immunologie, Hôpital Cochin, Pavillon Hardy A, 27 rue du Faubourg Saint-Jacques, 75674 Paris Cedex 14, France.

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December 2005

Synthesis of glycopeptides from type II collagen-incorporating galactosylated hydroxylysine mimetics and their use in studying the fine specificity of arthritogenic T cells.

Chembiochem 2005 Oct;6(10):1796-804

UPR 9021 CNRS-Immunologie et Chimie Thérapeutiques, Institut de Biologie Moléculaire et Cellulaire, 15 rue René Descartes, 67084 Strasbourg Cedex, France.

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http://doi.wiley.com/10.1002/cbic.200500075
Publisher Site
http://dx.doi.org/10.1002/cbic.200500075DOI Listing
October 2005

FADD adaptor in cancer.

Med Immunol 2005 Feb 17;4(1). Epub 2005 Feb 17.

Département d'Immunologie, Institut Cochin, INSERM U 567, CNRS UMR 8104, IFR 116, Université René Descartes, Paris V, Paris, France.

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http://dx.doi.org/10.1186/1476-9433-4-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC550674PMC
February 2005

Absence or low expression of fas-associated protein with death domain in acute myeloid leukemia cells predicts resistance to chemotherapy and poor outcome.

Cancer Res 2004 Nov;64(21):8101-8

Département d'Immunologie, Institut Cochin, Institut National de la Santé et de la Recherche Médicale U 567, Centre National de Recherche Scientifique UMR 8104, Institut Fédératif de Recherche 116, Université René Descartes, Paris V, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2361DOI Listing
November 2004

Ability of foot radiographs to predict rheumatoid arthritis in patients with early arthritis.

J Rheumatol 2004 Jan;31(1):66-70

Unit of Rheumatology and the Laboratory of Immunology, Hôpital de la Cavale Blanche, CHU Brest, Brest, France.

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January 2004

Loss of FADD protein expression results in a biased Fas-signaling pathway and correlates with the development of tumoral status in thyroid follicular cells.

Oncogene 2003 May;22(18):2795-804

Département d'Immunologie, Institut Cochin, INSERM U567, CNRS UMR 8104, IFR 116, Université René Descartes, 27 rue du fbg St-Jacques, 75014 Paris, France.

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http://dx.doi.org/10.1038/sj.onc.1206399DOI Listing
May 2003

IL-10 is necessary for FasL-induced protection from experimental autoimmune thyroiditis but not for FasL-induced immune deviation.

Eur J Immunol 2002 05;32(5):1292-9

Institut Cochin, Inserm U 567, CNRS UMR 8104, Laboratory member of IFR 116, Université René Descartes, Paris, France.

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http://dx.doi.org/10.1002/1521-4141(200205)32:5<1292::AID-IMMU1292>3.0.CO;2-YDOI Listing
May 2002