Publications by authors named "Giles W Robinson"

52Publications

The RACE to Develop New Targeted Therapies for Children With CNS Tumors.

Clin Pharmacol Ther 2020 Jul 7. Epub 2020 Jul 7.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/cpt.1937DOI Listing
July 2020

Genomics Paves the Way for Better Infant Medulloblastoma Therapy.

J Clin Oncol 2020 Jun 30;38(18):2010-2013. Epub 2020 Apr 30.

Department of Oncology, St Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1200/JCO.20.00593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302953PMC
June 2020

Food Is Love: Partnering With Families to Provide Nourishment at the End of Life.

J Clin Oncol 2020 Jun 2;38(16):1864-1867. Epub 2020 Apr 2.

St Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1200/JCO.20.00176DOI Listing
June 2020

Characterizing Posterior Fossa Syndrome: A Survey of Experts.

Pediatr Neurol 2020 03 29;104:19-22. Epub 2019 Nov 29.

Department of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2019.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010537PMC
March 2020

Medulloblastomics revisited: biological and clinical insights from thousands of patients.

Nat Rev Cancer 2020 01 9;20(1):42-56. Epub 2019 Dec 9.

Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41568-019-0223-8DOI Listing
January 2020

Medulloblastoma.

Nat Rev Dis Primers 2019 02 14;5(1):11. Epub 2019 Feb 14.

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41572-019-0063-6DOI Listing
February 2019

Advances in the classification of pediatric brain tumors through DNA methylation profiling: From research tool to frontline diagnostic.

Cancer 2018 11 26;124(21):4168-4180. Epub 2018 Sep 26.

Division of Neuro-Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://doi.wiley.com/10.1002/cncr.31583
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http://dx.doi.org/10.1002/cncr.31583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263826PMC
November 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

FDG-PET CT in the evaluation of primary and secondary pancreatic malignancies.

Pediatr Blood Cancer 2018 10 11;65(10):e27115. Epub 2018 May 11.

Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.27115DOI Listing
October 2018

Reoperation for Medulloblastoma Prior to Adjuvant Therapy.

Neurosurgery 2019 05;84(5):1050-1058

Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee.

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http://dx.doi.org/10.1093/neuros/nyy095DOI Listing
May 2019

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Marked functional recovery and imaging response of refractory optic pathway glioma to BRAFV600E inhibitor therapy: a report of two cases.

Childs Nerv Syst 2018 04 1;34(4):605-610. Epub 2018 Feb 1.

Department of Oncology, MS 260, Division of Neuro-Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00381-018-3739-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857244PMC
April 2018

Ovulation induction and oocyte retrieval for fertility preservation in young adolescents newly diagnosed with medulloblastoma: a case series.

J Obstet Gynaecol 2018 Aug 2;38(6):878-879. Epub 2018 Feb 2.

g Department of Oncology , St. Jude Children's Research Hospital , Memphis , TN , USA.

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http://dx.doi.org/10.1080/01443615.2017.1398222DOI Listing
August 2018

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Dev Cell 2017 12 2;43(6):673-688.e5. Epub 2017 Nov 2.

Department of Developmental Neurobiology, Neurobiology and Brain Tumor Program, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736446PMC
December 2017

Development of Molecularly Targeted Therapies to Treat Pediatric Malignancies.

Clin Pharmacol Ther 2017 Nov 24;102(5):752-753. Epub 2017 Aug 24.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/cpt.785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656826PMC
November 2017

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

Non-Malignant Cerebrospinal Fluid Ascites in a Patient with Atypical Teratoid Rhabdoid Tumor.

Oncol Res Treat 2017 21;40(4):216-219. Epub 2017 Mar 21.

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http://dx.doi.org/10.1159/000458441DOI Listing
November 2017

Exploiting Laboratory Insights to Improve Outcomes of Pediatric Central Nervous System Tumors.

Am Soc Clin Oncol Educ Book 2016 ;35:e540-6

From the Division of Neuro-Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN; Division of Pediatric Neurooncology, German Cancer Research Center, Heidelberg, Germany; Center for Data Driven Discovery in Biomedicine, Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/EDBK_159149DOI Listing
January 2017

Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant.

Drug Metab Dispos 2016 07 6;44(7):1116-22. Epub 2016 Apr 6.

Department of Pharmaceutical Sciences (J.K.R., A.V.B., V.M.D., J.C.P., C.F.S.), Department of Biostatistics (T.L.), and Department of Oncology (A.B., G.W.R., A.J.G.), St. Jude Children's Research Hospital, Memphis, Tennessee

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.115.068676
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http://dx.doi.org/10.1124/dmd.115.068676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931885PMC
July 2016

Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors.

J Neurooncol 2016 Jan 30;126(2):225-34. Epub 2015 Oct 30.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s11060-015-1965-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718940PMC
January 2016

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

J Clin Oncol 2015 Aug 13;33(24):2646-54. Epub 2015 Jul 13.

Giles W. Robinson, Brent A. Orr, Gang Wu, Tong Lin, Ibrahim Qaddoumi, Sue C. Kaste, Michael Rusch, Sariah J. Allen, Arzu Onar-Thomas, Clinton F. Stewart, James M. Boyett, Richard J. Gilbertson, David W. Ellison, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Sridharan Gururangan and Annick Desjardins, Duke University Medical Center, Durham, NC; Roger J. Packer, Children's National Medical Center, Washington, DC; Stewart Goldman, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Michael D. Prados, University of California San Francisco, San Francisco, CA; Murali Chintagumpala, Texas Children's Cancer Center, Houston, TX; Naoko Takebe, National Cancer Institute, Bethesda, MD; Maryam Fouladi, Cincinnati Children's Hospital, Cincinnati, OH; and Tom Curran, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2014.60.1591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534527PMC
August 2015

Medulloblastoma-translating discoveries from the bench to the bedside.

Nat Rev Clin Oncol 2014 Dec 28;11(12):714-22. Epub 2014 Oct 28.

Department of Oncology, Division of Neuro-Oncology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1038/nrclinonc.2014.181DOI Listing
December 2014

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.

Nature 2014 Jul 22;511(7510):428-34. Epub 2014 Jun 22.

1] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany [2] Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg 69120, Germany.

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http://www.abta.org/resources/enhancers-hijacking-activates.
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http://www.nature.com/doifinder/10.1038/nature13379
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http://dx.doi.org/10.1038/nature13379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201514PMC
July 2014

Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy.

BMC Cancer 2014 Apr 12;14:258. Epub 2014 Apr 12.

Division of Neuro-Oncology, Department of Oncology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1186/1471-2407-14-258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996187PMC
April 2014

Role of MYC in Medulloblastoma.

Cold Spring Harb Perspect Med 2013 Nov 1;3(11). Epub 2013 Nov 1.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.

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http://dx.doi.org/10.1101/cshperspect.a014308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808772PMC
November 2013

Impact of tumor location on medulloblastoma subtyping and treatment.

Authors:
Giles W Robinson

Pediatr Blood Cancer 2013 Sep 20;60(9):1393-4. Epub 2013 Apr 20.

St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1002/pbc.24549DOI Listing
September 2013

Medulloblastomics: the end of the beginning.

Nat Rev Cancer 2012 Dec;12(12):818-34

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nrc3410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889646PMC
December 2012