Giel Hendriks

Giel Hendriks

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Giel Hendriks

Giel Hendriks

Publications by authors named "Giel Hendriks"

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31Publications

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The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system.

Toxicol In Vitro 2019 Jul 4;61:104594. Epub 2019 Jul 4.

Heriot Watt University, School of Engineering and Physical Sciences, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2019.104594DOI Listing
July 2019

The functional impact of variants of uncertain significance in BRCA2.

Genet Med 2019 02 10;21(2):293-302. Epub 2018 Jul 10.

Department of Human Genetics, Leiden University Medical Center, PO Box 9600, Leiden, 2300RC, The Netherlands.

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http://dx.doi.org/10.1038/s41436-018-0052-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752316PMC
February 2019

Mechanistic insight into reactivity and (geno)toxicity of well-characterized nanoparticles of cobalt metal and oxides.

Nanotoxicology 2018 08 23;12(6):602-620. Epub 2018 May 23.

a Institute of Environmental Medicine , Karolinska Institutet , Stockholm , Sweden.

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http://dx.doi.org/10.1080/17435390.2018.1470694DOI Listing
August 2018

Good cell culture practices &in vitro toxicology.

Toxicol In Vitro 2017 Dec 25;45(Pt 3):272-277. Epub 2017 Apr 25.

CAAT-Europe, Konstanz University, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2017.04.022DOI Listing
December 2017

Emerging metrology for high-throughput nanomaterial genotoxicology.

Mutagenesis 2017 01 26;32(1):215-232. Epub 2016 Aug 26.

Swansea University Medical School, Institute of Life Science, Centre for NanoHealth, Swansea University Medical School, Wales SA2 8PP, UK.

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http://dx.doi.org/10.1093/mutage/gew037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500194PMC
January 2017

The Vitotox and ToxTracker assays: A two-test combination for quick and reliable assessment of genotoxic hazards.

Mutat Res 2016 Nov 12;810:13-21. Epub 2016 Sep 12.

Department of Food, Medicines and Consumer Safety, Unit of Toxicology, Scientific Institute of Public Health (WIV-ISP), Juliette Wytsmanstraat 14, B-1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrgentox.2016.09.005DOI Listing
November 2016

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.

Arch Toxicol 2016 May 31;90(5):1163-79. Epub 2015 May 31.

Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00204-015-1536-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830895PMC
May 2016

A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.

Arch Toxicol 2015 Dec 2;89(12):2413-27. Epub 2014 Oct 2.

Center for Health Protection, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA, Bilthoven, The Netherlands.

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http://dx.doi.org/10.1007/s00204-014-1368-6DOI Listing
December 2015

Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines.

Part Fibre Toxicol 2014 Sep 2;11:41. Epub 2014 Sep 2.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://particleandfibretoxicology.biomedcentral.com/articles
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http://dx.doi.org/10.1186/s12989-014-0041-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237954PMC
September 2014

Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.

Chem Res Toxicol 2014 Mar 5;27(3):338-55. Epub 2014 Feb 5.

Division of Toxicology, Leiden Academic Centre for Drug Research (LACDR), Leiden University , The Netherlands.

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http://pubs.acs.org/doi/10.1021/tx4004038
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http://dx.doi.org/10.1021/tx4004038DOI Listing
March 2014

Cellular-signaling pathways unveil the carcinogenic potential of chemicals.

J Appl Toxicol 2013 Jun 22;33(6):399-409. Epub 2013 Jan 22.

Department of Toxicogenetics, Leiden University Medical Center, PO Box 9600, 2300, RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/jat.2845DOI Listing
June 2013

Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment.

Mutat Res 2011 May 4;709-710:49-59. Epub 2011 Mar 4.

Department of Toxicogenetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.mrfmmm.2011.02.013DOI Listing
May 2011

Transcription and replication: far relatives make uneasy bedfellows.

Cell Cycle 2010 Jun 15;9(12):2300-4. Epub 2010 Jun 15.

Department of Cancer Biology and Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.4161/cc.9.12.11987DOI Listing
June 2010

Mammalian polymerase zeta is essential for post-replication repair of UV-induced DNA lesions.

DNA Repair (Amst) 2009 Dec 27;8(12):1444-51. Epub 2009 Sep 27.

Department of Toxicogenetics, Leiden University Medical Center, Einthovenweg 20, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.dnarep.2009.09.006DOI Listing
December 2009

LIP5 interacts with aquaporin 2 and facilitates its lysosomal degradation.

J Am Soc Nephrol 2009 May 8;20(5):990-1001. Epub 2009 Apr 8.

Department of Physiology, Nijmegen Center of Molecular Sciences, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1681/ASN.2008060648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678037PMC
May 2009

Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells.

DNA Repair (Amst) 2008 Aug 9;7(8):1330-9. Epub 2008 Jun 9.

Department of Toxicogenetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.dnarep.2008.04.015DOI Listing
August 2008

Missorting of the Aquaporin-2 mutant E258K to multivesicular bodies/lysosomes in dominant NDI is associated with its monoubiquitination and increased phosphorylation by PKC but is due to the loss of E258.

Pflugers Arch 2008 Mar 27;455(6):1041-54. Epub 2007 Oct 27.

Department of Physiology, Radboud University Nijmegen Medical Center, Research Tower, 7th floor; UMC St Radboud, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/s00424-007-0364-6
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http://dx.doi.org/10.1007/s00424-007-0364-6DOI Listing
March 2008

Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel.

Proc Natl Acad Sci U S A 2006 Nov 13;103(48):18344-9. Epub 2006 Nov 13.

Department of Physiology, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0604073103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838753PMC
November 2006

Polarisation, key to good localisation.

Biochim Biophys Acta 2006 Aug 31;1758(8):1126-33. Epub 2006 Mar 31.

Department of Physiology, Nijmegen Center for Molecular Life Science, Radboud University Nijmegen Medical Centre, Rm 7.83, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.bbamem.2006.03.007DOI Listing
August 2006