Gibran Hemani

Gibran Hemani

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Gibran Hemani

Publications by authors named "Gibran Hemani"

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Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies.

Behav Genet 2019 May 2;49(3):327-339. Epub 2019 Jan 2.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1007/s10519-018-9944-9DOI Listing
May 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis.

Ann Neurol 2019 Apr 13;85(4):470-481. Epub 2019 Mar 13.

Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1002/ana.25431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450729PMC
April 2019

Prenatal alcohol exposure and facial morphology in a UK cohort.

Drug Alcohol Depend 2019 04 5;197:42-47. Epub 2019 Feb 5.

MRC Integrative Epidemiology Unit, Population Health Sciences, Oakfield House, Oakfield Grove, University of Bristol, BS8 2BN, UK; Bristol Dental School, University of Bristol, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2018.11.031DOI Listing
April 2019

Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

Hum Genet 2019 Apr 27. Epub 2019 Apr 27.

MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1007/s00439-019-02014-8DOI Listing
April 2019

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome.

Elife 2019 Mar 5;8. Epub 2019 Mar 5.

MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.7554/eLife.43657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400585PMC
March 2019

Schizophrenia risk and reproductive success: a Mendelian randomization study.

R Soc Open Sci 2019 Mar 6;6(3):181049. Epub 2019 Mar 6.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1098/rsos.181049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458425PMC
March 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Nat Commun 2019 01 3;10(1):29. Epub 2019 Jan 3.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC, 27516-8050, USA.

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http://www.nature.com/articles/s41467-018-07867-7
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http://dx.doi.org/10.1038/s41467-018-07867-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318312PMC
January 2019

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis.

Nat Commun 2019 01 18;10(1):333. Epub 2019 Jan 18.

Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1038/s41467-018-08219-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338768PMC
January 2019

Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.

Am J Hum Genet 2018 10 13;103(4):461-473. Epub 2018 Sep 13.

Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02139, USA; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183027
Publisher Site
http://dx.doi.org/10.1016/j.ajhg.2018.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174360PMC
October 2018

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease.

Hum Mol Genet 2018 09;27(18):3293-3304

MRC Integrative Epidemiology Unit (IEU), Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK.

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http://dx.doi.org/10.1093/hmg/ddy210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121186PMC
September 2018

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes.

J Autoimmun 2018 09 29;93:66-75. Epub 2018 Jun 29.

MRC Integrative Epidemiology Unit, Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183020
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http://dx.doi.org/10.1016/j.jaut.2018.06.005DOI Listing
September 2018

Evaluating the potential role of pleiotropy in Mendelian randomization studies.

Hum Mol Genet 2018 08;27(R2):R195-R208

MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol.

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https://academic.oup.com/hmg/article/27/R2/R195/4996734
Publisher Site
http://dx.doi.org/10.1093/hmg/ddy163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061876PMC
August 2018

Telomere Length and Risk of Cancer and Non-neoplastic Diseases: Is Survivin the Ariadne's Thread?-Reply.

JAMA Oncol 2017 12;3(12):1741-1742

Center of Human Development and Aging, Department of Pediatrics, New Jersey Medical School, Rutgers, State University of New Jersey, Newark

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http://dx.doi.org/10.1001/jamaoncol.2017.2316DOI Listing
December 2017

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study.

Diabetologia 2017 11 9;60(11):2210-2220. Epub 2017 Sep 9.

MRC Integrative Epidemiology Unit, University of Bristol, Rm OS11, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1007/s00125-017-4396-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342872PMC
November 2017

Orienting the causal relationship between imprecisely measured traits using GWAS summary data.

PLoS Genet 2017 Nov 17;13(11):e1007081. Epub 2017 Nov 17.

MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, School of Social and Community Medicine, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1007081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711033PMC
November 2017

Recent Developments in Mendelian Randomization Studies.

Curr Epidemiol Rep 2017 22;4(4):330-345. Epub 2017 Nov 22.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Bristol, UK.

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http://dx.doi.org/10.1007/s40471-017-0128-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711966PMC
November 2017

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

Am J Hum Genet 2017 Oct;101(4):590-602

MRC Integrative Epidemiology Unit, Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1016/j.ajhg.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630190PMC
October 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique.

Int J Epidemiol 2016 12;45(6):1717-1726

Medical Research Council Integrative Epidemiology Unit at the University of Bristol.

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http://dx.doi.org/10.1093/ije/dyx028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722032PMC
December 2016

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants.

Hum Mol Genet 2016 10 24;25(19):4339-4349. Epub 2016 Aug 24.

MRC Integrative Epidemiology Unit (IEU), School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK

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http://dx.doi.org/10.1093/hmg/ddw283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291201PMC
October 2016

Genome-wide associations for birth weight and correlations with adult disease.

Authors:
Momoko Horikoshi Robin N Beaumont Felix R Day Nicole M Warrington Marjolein N Kooijman Juan Fernandez-Tajes Bjarke Feenstra Natalie R van Zuydam Kyle J Gaulton Niels Grarup Jonathan P Bradfield David P Strachan Ruifang Li-Gao Tarunveer S Ahluwalia Eskil Kreiner Rico Rueedi Leo-Pekka Lyytikäinen Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Jouke-Jan Hottenga Natalia Vilor-Tejedor Peter K Joshi Eileen Tai Hui Boh Ioanna Ntalla Niina Pitkänen Anubha Mahajan Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Michael Nodzenski Louise A Diver Krina T Zondervan Mariona Bustamante Pedro Marques-Vidal Josep M Mercader Amanda J Bennett Nilufer Rahmioglu Dale R Nyholt Ronald Ching Wan Ma Claudia Ha Ting Tam Wing Hung Tam Santhi K Ganesh Frank Ja van Rooij Samuel E Jones Po-Ru Loh Katherine S Ruth Marcus A Tuke Jessica Tyrrell Andrew R Wood Hanieh Yaghootkar Denise M Scholtens Lavinia Paternoster Inga Prokopenko Peter Kovacs Mustafa Atalay Sara M Willems Kalliope Panoutsopoulou Xu Wang Lisbeth Carstensen Frank Geller Katharina E Schraut Mario Murcia Catharina Em van Beijsterveldt Gonneke Willemsen Emil V R Appel Cilius E Fonvig Caecilie Trier Carla Mt Tiesler Marie Standl Zoltán Kutalik Sílvia Bonas-Guarch David M Hougaard Friman Sánchez David Torrents Johannes Waage Mads V Hollegaard Hugoline G de Haan Frits R Rosendaal Carolina Medina-Gomez Susan M Ring Gibran Hemani George McMahon Neil R Robertson Christopher J Groves Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Frank D Mentch Scott M MacKenzie Rebecca M Reynolds William L Lowe Anke Tönjes Michael Stumvoll Virpi Lindi Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Thorkild Ia Sørensen Harri Niinikoski Katja Pahkala Olli T Raitakari Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Mads Melbye Harry Campbell James F Wilson Martine Vrijheid Eco Jcn de Geus Dorret I Boomsma Haja N Kadarmideen Jens-Christian Holm Torben Hansen Sylvain Sebert Andrew T Hattersley Lawrence J Beilin John P Newnham Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Mika Kähönen Jorma S Viikari Terho Lehtimäki Peter Vollenweider Klaus Bønnelykke Hans Bisgaard Dennis O Mook-Kanamori Albert Hofman Fernando Rivadeneira André G Uitterlinden Charlotta Pisinger Oluf Pedersen Christine Power Elina Hyppönen Nicholas J Wareham Hakon Hakonarson Eleanor Davies Brian R Walker Vincent Wv Jaddoe Marjo-Riitta Jarvelin Struan Fa Grant Allan A Vaag Debbie A Lawlor Timothy M Frayling George Davey Smith Andrew P Morris Ken K Ong Janine F Felix Nicholas J Timpson John Rb Perry David M Evans Mark I McCarthy Rachel M Freathy

Nature 2016 10 28;538(7624):248-252. Epub 2016 Sep 28.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/nature19806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164934PMC
October 2016

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

JAMA Psychiatry 2016 05;73(5):497-505

Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785705PMC
May 2016

Systematic identification of genetic influences on methylation across the human life course.

Genome Biol 2016 Mar 31;17:61. Epub 2016 Mar 31.

MRC Integrative Epidemiology Unit (IEU) & School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1186/s13059-016-0926-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818469PMC
March 2016

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.

Hum Mol Genet 2015 Dec 22;24(25):7445-9. Epub 2015 Oct 22.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia, The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane, QLD 4102, Australia.

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http://dx.doi.org/10.1093/hmg/ddv443DOI Listing
December 2015

The role of common genetic variation in educational attainment and income: evidence from the National Child Development Study.

Sci Rep 2015 Nov 12;5:16509. Epub 2015 Nov 12.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, United Kingdom.

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http://dx.doi.org/10.1038/srep16509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642349PMC
November 2015

Directional dominance on stature and cognition in diverse human populations.

Authors:
Peter K Joshi Tonu Esko Hannele Mattsson Niina Eklund Ilaria Gandin Teresa Nutile Anne U Jackson Claudia Schurmann Albert V Smith Weihua Zhang Yukinori Okada Alena Stančáková Jessica D Faul Wei Zhao Traci M Bartz Maria Pina Concas Nora Franceschini Stefan Enroth Veronique Vitart Stella Trompet Xiuqing Guo Daniel I Chasman Jeffery R O'Connel Tanguy Corre Suraj S Nongmaithem Yuning Chen Massimo Mangino Daniela Ruggiero Michela Traglia Aliki-Eleni Farmaki Tim Kacprowski Andrew Bjonnes Ashley van der Spek Ying Wu Anil K Giri Lisa R Yanek Lihua Wang Edith Hofer Cornelius A Rietveld Olga McLeod Marilyn C Cornelis Cristian Pattaro Niek Verweij Clemens Baumbach Abdel Abdellaoui Helen R Warren Dragana Vuckovic Hao Mei Claude Bouchard John R B Perry Stefania Cappellani Saira S Mirza Miles C Benton Ulrich Broeckel Sarah E Medland Penelope A Lind Giovanni Malerba Alexander Drong Loic Yengo Lawrence F Bielak Degui Zhi Peter J van der Most Daniel Shriner Reedik Mägi Gibran Hemani Tugce Karaderi Zhaoming Wang Tian Liu Ilja Demuth Jing Hua Zhao Weihua Meng Lazaros Lataniotis Sander W van der Laan Jonathan P Bradfield Andrew R Wood Amelie Bonnefond Tarunveer S Ahluwalia Leanne M Hall Erika Salvi Seyhan Yazar Lisbeth Carstensen Hugoline G de Haan Mark Abney Uzma Afzal Matthew A Allison Najaf Amin Folkert W Asselbergs Stephan J L Bakker R Graham Barr Sebastian E Baumeister Daniel J Benjamin Sven Bergmann Eric Boerwinkle Erwin P Bottinger Archie Campbell Aravinda Chakravarti Yingleong Chan Stephen J Chanock Constance Chen Y-D Ida Chen Francis S Collins John Connell Adolfo Correa L Adrienne Cupples George Davey Smith Gail Davies Marcus Dörr Georg Ehret Stephen B Ellis Bjarke Feenstra Mary F Feitosa Ian Ford Caroline S Fox Timothy M Frayling Nele Friedrich Frank Geller Generation Scotland Irina Gillham-Nasenya Omri Gottesman Misa Graff Francine Grodstein Charles Gu Chris Haley Christopher J Hammond Sarah E Harris Tamara B Harris Nicholas D Hastie Nancy L Heard-Costa Kauko Heikkilä 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Nature 2015 Jul 1;523(7561):459-462. Epub 2015 Jul 1.

Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.

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July 2015

Dominance genetic variation contributes little to the missing heritability for human complex traits.

Am J Hum Genet 2015 Mar 12;96(3):377-85. Epub 2015 Feb 12.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia; The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane, QLD 4102, Australia. Electronic address:

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Nat Rev Genet 2014 Nov 9;15(11):722-33. Epub 2014 Sep 9.

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November 2014

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Nat Genet 2014 Nov 5;46(11):1173-86. Epub 2014 Oct 5.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.

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November 2014

Hemani et al. reply.

Nature 2014 Oct;514(7520):E5-6

1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia [2] University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland 4072, Australia.

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October 2014

Mendelian randomization: genetic anchors for causal inference in epidemiological studies.

Hum Mol Genet 2014 Sep 4;23(R1):R89-98. Epub 2014 Jul 4.

MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, School of Social and Community Medicine, Bristol, UK.

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September 2014

Detection and replication of epistasis influencing transcription in humans.

Nature 2014 Apr 26;508(7495):249-53. Epub 2014 Feb 26.

1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia [2] University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland 4072, Australia [3].

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April 2014

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.

PLoS Genet 2014 Apr 10;10(4):e1004269. Epub 2014 Apr 10.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia; The University of Queensland Diamantina Institute, The Translational Research Institute, Brisbane, Queensland, Australia.

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April 2014

Response to Lee et al.: SNP-based heritability analysis with dense data.

Am J Hum Genet 2013 Dec;93(6):1155-7

UCL Genetics Institute, University College London, London WC1E 6BT, UK. Electronic address:

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December 2013

Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data.

PLoS Genet 2013 May 16;9(5):e1003502. Epub 2013 May 16.

University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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May 2013

An evolutionary perspective on epistasis and the missing heritability.

PLoS Genet 2013 Feb 28;9(2):e1003295. Epub 2013 Feb 28.

The Roslin Institute and Royal (Dick) School of Veterinary Science, University of Edinburgh, Edinburgh, United Kingdom.

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February 2013

Improved heritability estimation from genome-wide SNPs.

Am J Hum Genet 2012 Dec;91(6):1011-21

University College London Genetics Institute, University College London, London WC1E 6BT, UK.

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December 2012

Genome-wide analysis of mitral valve disease in Cavalier King Charles Spaniels.

Vet J 2012 Jul 2;193(1):283-6. Epub 2011 Nov 2.

Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Roslin, Midlothian EH25 9RG, UK.

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July 2012

EpiGPU: exhaustive pairwise epistasis scans parallelized on consumer level graphics cards.

Bioinformatics 2011 Jun 6;27(11):1462-5. Epub 2011 Apr 6.

Division of Genetics and Genomics, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

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June 2011