Publications by authors named "Gianpietro Dotti"

166Publications

Extending the Promise of Chimeric Antigen Receptor T-Cell Therapy Beyond Targeting CD19 Tumors.

J Clin Oncol 2021 Jan 12:JCO2001738. Epub 2021 Jan 12.

Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

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January 2021

Combining Oncolytic Viruses with CAR T Cell Therapy.

Hum Gene Ther 2020 Dec 21. Epub 2020 Dec 21.

University of North Carolina at Chapel Hill School of Medicine, 6797, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States.

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December 2020

Cryo-shocked cancer cells for targeted drug delivery and vaccination.

Sci Adv 2020 Dec 9;6(50). Epub 2020 Dec 9.

Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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December 2020

Activation and degranulation of CAR-T cells using engineered antigen-presenting cell surfaces.

PLoS One 2020 25;15(9):e0238819. Epub 2020 Sep 25.

FIT BEST Laboratory, Department of Chemical, Biological, and Bioengineering, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, United States of America.

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November 2020

Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma.

Nat Commun 2020 09 23;11(1):4810. Epub 2020 Sep 23.

Department of Pathology, Immunology and Laboratory Medicine, Rutgers University-New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA.

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September 2020

The Role of Immunological Synapse in Predicting the Efficacy of Chimeric Antigen Receptor (CAR) Immunotherapy.

Cell Commun Signal 2020 08 25;18(1):134. Epub 2020 Aug 25.

Department of Pathology, Immunology and Laboratory Medicine, Rutgers University- New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA.

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August 2020

Scaffold-Mediated Static Transduction of T Cells for CAR-T Cell Therapy.

Adv Healthc Mater 2020 07 11;9(14):e2000275. Epub 2020 Jun 11.

Joint Department of Biomedical Engineering, University of North Carolina - Chapel Hill and North Carolina State University - Raleigh, 1840 Enterpreneur Way, Raleigh, NC, 27695, USA.

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July 2020

Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy.

Proc Natl Acad Sci U S A 2020 02 6;117(7):3687-3692. Epub 2020 Feb 6.

Department of Bioengineering, University of California, Los Angeles, CA 90095;

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February 2020

Enhancing Chimeric Antigen Receptor T-Cell Efficacy in Solid Tumors.

Clin Cancer Res 2020 06 3;26(11):2444-2451. Epub 2020 Feb 3.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.

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June 2020

THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells.

Cancer Cell 2020 02 30;37(2):216-225.e6. Epub 2020 Jan 30.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

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February 2020

A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor.

Cancer Immunol Res 2020 01 12;8(1):57-69. Epub 2019 Nov 12.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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January 2020

Red blood cell-derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy.

Sci Adv 2019 10 23;5(10):eaaw6870. Epub 2019 Oct 23.

Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.

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October 2019

Computationally Guided Design of Single-Chain Variable Fragment Improves Specificity of Chimeric Antigen Receptors.

Mol Ther Oncolytics 2019 Dec 31;15:30-37. Epub 2019 Aug 31.

Departments of Pharmacology and Biochemistry & Molecular Biology, Penn State College of Medicine, Hershey, PA 17033, USA.

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December 2019