Gianni Soraru

Gianni Soraru

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Gianni Soraru

Gianni Soraru

Publications by authors named "Gianni Soraru"

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Transforming growth factor beta 1 signaling is altered in the spinal cord and muscle of amyotrophic lateral sclerosis mice and patients.

Neurobiol Aging 2019 Oct 10;82:48-59. Epub 2019 Jul 10.

Dipartimento di Scienze Farmacologiche e Biomolecolari (DiSFeB), Centro di Eccellenza sulle Malattie Neurodegenerative, Università degli Studi di Milano, Milano, Italy; Centro InterUniversitario sulle Malattie Neurodegenerative, Università degli Studi di Firenze, Roma Tor Vergata and Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.07.001DOI Listing
October 2019

Safety and efficacy of edaravone compared to historical controls in patients with amyotrophic lateral sclerosis from North-Eastern Italy.

J Neurol Sci 2019 Sep 6;404:47-51. Epub 2019 Jun 6.

Neuromuscular Center, Department of Neurosciences, University of Padova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.06.006DOI Listing
September 2019

Preliminary design and validation of the "6-K-scale" for bulbar symptoms evaluation in SBMA.

Neurol Sci 2019 Jul 26;40(7):1393-1401. Epub 2019 Mar 26.

Neuromuscular Center, Department of Neurosciences, University of Padova, Padua, Italy.

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http://dx.doi.org/10.1007/s10072-019-03850-2DOI Listing
July 2019

Brain MRI shows white matter sparing in Kennedy's disease and slow-progressing lower motor neuron disease.

Hum Brain Mapp 2019 07 28;40(10):3102-3112. Epub 2019 Mar 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1002/hbm.24583DOI Listing
July 2019

Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy.

Neurology 2019 Mar 20;92(11):e1205-e1211. Epub 2019 Feb 20.

From the Institute of Neurology (V.L., O.J.Z., L.Z., C.H., M.F., C.-H.L., B.M., H.Z., A.H., L.G., M.H., P.F.), University College London Institute of Neurology, Queen Square, London; Blizard Institute (V.L., A.M.), Queen Mary, University of London, UK; Department of Neurosciences (G.Q., I.M., C.B., G.S.), University of Padova, Italy; Department of Neurology (C.-H.L.), China Medical University Hospital, Taiwan; Basildon Hospital (K.A.), UK; Department of Physiology, Anatomy and Genetics (C.R.), University of Oxford; UK Dementia Research Institute at UCL (H.Z., A.H.), London, UK; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital; and the Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511101PMC
March 2019

Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial.

Lancet Neurol 2019 Feb 13;18(2):155-164. Epub 2018 Dec 13.

Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183040
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http://dx.doi.org/10.1016/S1474-4422(18)30406-XDOI Listing
February 2019

The clinical spectrum of -related myopathy.

Neurology 2018 10 26;91(17):e1629-e1641. Epub 2018 Sep 26.

From the Neuromuscular Center (C.S., C.B., L.B., B.P., F.G., S.V., B.F.G., G.S., E.P.), Department of Neurosciences, and Departments of Cardiac, Thoracic and Vascular Sciences (M.P., C.C.), Biomedical Sciences (G.M., S.C.E.T.), and Medicine (R.S.), Section of Radiology, University of Padova, Italy; Dubowitz Neuromuscular Centre (Developmental Neuroscience Programme) (F.C.), UCL Great Ormond Street Institute of Child Health, University College London, UK; Neuromuscular and Rare Disease Unit (I.C., M.M.), Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan; Department of Biomedical and Neuromotor Sciences (G.C., V.P.), University of Bologna; and CNR Institute of Neuroscience (S.C.E.T.), Padova, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000006387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205688PMC
October 2018

Beyond motor neurons: expanding the clinical spectrum in Kennedy's disease.

J Neurol Neurosurg Psychiatry 2018 08 20;89(8):808-812. Epub 2018 Jan 20.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2017-316961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204939PMC
August 2018

Multimodal structural MRI in the diagnosis of motor neuron diseases.

Neuroimage Clin 2017 2;16:240-247. Epub 2017 Aug 2.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/j.nicl.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545829PMC
April 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Validation of the Italian version of the SBMA Functional Rating Scale as outcome measure.

Neurol Sci 2016 Nov 21;37(11):1815-1821. Epub 2016 Jul 21.

Department of Neurosciences, Neuromuscular Center, University of Padova, Via Giustiniani 5, 35128, Padua, Italy.

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http://dx.doi.org/10.1007/s10072-016-2666-yDOI Listing
November 2016

Mitochondrial implications in bulbospinal muscular atrophy (Kennedy disease).

Amyotroph Lateral Scler Frontotemporal Degener 2015 1;17(1-2):112-8. Epub 2015 Oct 1.

e Department of Neurosciences , University of Padova , Italy.

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http://dx.doi.org/10.3109/21678421.2015.1089910DOI Listing
October 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Onset Manifestations of Spinal and Bulbar Muscular Atrophy (Kennedy's Disease).

J Mol Neurosci 2016 Mar 19;58(3):321-9. Epub 2015 Oct 19.

Department of Neurosciences, University of Padova, Padova, Italy.

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http://dx.doi.org/10.1007/s12031-015-0663-xDOI Listing
March 2016

210th ENMC International Workshop: Research and clinical management of patients with spinal and bulbar muscular atrophy, 27-29 March, 2015, Naarden, The Netherlands.

Neuromuscul Disord 2015 Oct 19;25(10):802-12. Epub 2015 Jun 19.

Department of Neurosciences, University of Padova, Padova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2015.06.462DOI Listing
October 2015

Impact on children of a parent with ALS: a case-control study.

Front Psychol 2015 17;6:288. Epub 2015 Mar 17.

Department of Philosophy, Sociology, Pedagogy and Applied Psychology, University of Padova Padova, Italy.

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http://dx.doi.org/10.3389/fpsyg.2015.00288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362044PMC
April 2015

Skeletal muscle satellite cells in amyotrophic lateral sclerosis.

Ultrastruct Pathol 2014 Oct 31;38(5):295-302. Epub 2014 Jul 31.

Department of Biomedical and Neuromotor Sciences, University of Bologna , Bologna , Italy .

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http://dx.doi.org/10.3109/01913123.2014.937842DOI Listing
October 2014

Improving the knowledge of amyotrophic lateral sclerosis genetics: novel SOD1 and FUS variants.

Neurobiol Aging 2014 May 29;35(5):1212.e7-1212.e10. Epub 2013 Oct 29.

Laboratory of Human Genetics, Department of Biology, University of Padova, Padova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.10.093DOI Listing
May 2014

Specific numerical processing impairment in ALS patients.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Jan 6;14(1):6-12. Epub 2012 Sep 6.

Department of Philosophy, Sociology, Pedagogy and Applied Psychology, University of Padova, Padova, Italy.

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http://www.tandfonline.com/doi/full/10.3109/17482968.2012.71
Publisher Site
http://dx.doi.org/10.3109/17482968.2012.719235DOI Listing
January 2013

Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis.

Neurobiol Dis 2013 Jan 4;49:107-17. Epub 2012 Sep 4.

Division of Regenerative Medical Engineering, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo, 113-0033 Tokyo, Japan. Electronic address:

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http://aups.org.au/Proceedings/43/139P/139P.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S096999611200302
Publisher Site
http://dx.doi.org/10.1016/j.nbd.2012.08.015DOI Listing
January 2013

Efficacy of hypnosis-based treatment in amyotrophic lateral sclerosis: a pilot study.

Front Psychol 2012 5;3:465. Epub 2012 Nov 5.

Department of Philosophy, Sociology, Pedagogy and Applied Psychology, University of Padova Padova, Italy.

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http://dx.doi.org/10.3389/fpsyg.2012.00465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498876PMC
November 2012

Mutational analysis of VCP gene in familial amyotrophic lateral sclerosis.

Neurobiol Aging 2012 Mar 3;33(3):630.e1-2. Epub 2011 Dec 3.

Department of Neurology and Laboratory of Neuroscience, IRCCS, Istituto Auxologico Italiano, Milan, Italy.

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http://dx.doi.org/10.1016/j.neurobiolaging.2011.10.025DOI Listing
March 2012

Survival and quality of life after tracheostomy for acute respiratory failure in patients with amyotrophic lateral sclerosis.

J Crit Care 2011 Jun 23;26(3):329.e7-14. Epub 2010 Jul 23.

Respiratory Intensive Care Unit, City Hospital of Padova, Padova 35128, Italy.

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http://dx.doi.org/10.1016/j.jcrc.2010.06.003DOI Listing
June 2011

Survival and quality of life after tracheostomy for acute respiratory failure in patients with amyotrophic lateral sclerosis.

J Crit Care 2011 Jun 23;26(3):329.e7-14. Epub 2010 Jul 23.

Respiratory Intensive Care Unit, City Hospital of Padova, Padova 35128, Italy.

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http://dx.doi.org/10.1016/j.jcrc.2010.06.003DOI Listing
June 2011

A pilot trial with clenbuterol in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2006 Dec;7(4):246-8

Department of Neurosciences, Neurology Unit, Piove di Sacco Hospital, Padova, Italy.

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http://dx.doi.org/10.1080/14660820600600558DOI Listing
December 2006