Gianluigi Mancardi

Gianluigi Mancardi

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Gianluigi Mancardi

Gianluigi Mancardi

Publications by authors named "Gianluigi Mancardi"

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68Publications

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Cardiovascular autonomic individual profile of relapsing-remitting multiple sclerosis patients and risk of extending cardiac monitoring after first dose fingolimod.

J Neurol Sci 2019 Oct 8;405:116423. Epub 2019 Aug 8.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Maternal and Child Health, University of Genova, Genova, Italy; IRCCS Maugeri Scientific Clinical Institutes, Genova Nervi-Pavia, Italy.

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http://dx.doi.org/10.1016/j.jns.2019.116423DOI Listing
October 2019

Clinical, laboratory features, and prognostic factors in adult acute transverse myelitis: an Italian multicenter study.

Neurol Sci 2019 Jul 22;40(7):1383-1391. Epub 2019 Mar 22.

Department of Biomedical, Metabolic and Neurosciences, University of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.1007/s10072-019-03830-6DOI Listing
July 2019

CSF oligoclonal bands and normal appearing white matter periventricular damage in patients with clinically isolated syndrome suggestive of MS.

Mult Scler Relat Disord 2019 Jun 2;31:93-96. Epub 2019 Apr 2.

IRCCS Ospedale Policlinico, San Martino, Genova; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health and CEBR, University of Genoa, Genoa, Italy; Departments of Neurology, Radiology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.1016/j.msard.2019.03.027DOI Listing
June 2019

Management of acute ischemic stroke, thrombolysis rate, and predictors of clinical outcome.

Neurol Sci 2019 Feb 14;40(2):319-326. Epub 2018 Nov 14.

Policlinic San Martino Hospital, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, Genoa, Italy.

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http://link.springer.com/10.1007/s10072-018-3644-3
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http://dx.doi.org/10.1007/s10072-018-3644-3DOI Listing
February 2019

Ecological impact of isolated cognitive relapses in MS.

Mult Scler 2018 Nov 15:1352458518813722. Epub 2018 Nov 15.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Health, University of Genoa, Genoa, Italy/IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

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http://dx.doi.org/10.1177/1352458518813722DOI Listing
November 2018

National Institutes of Health Stroke Scale in patients with primary intracerebral hemorrhage.

Neurol Sci 2018 Oct 16;39(10):1751-1755. Epub 2018 Jul 16.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova and San Martino Teaching Hospital, Largo Daneo 3, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s10072-018-3495-yDOI Listing
October 2018

Overexpression of sphingosine-1-phosphate receptors on reactive astrocytes drives neuropathology of multiple sclerosis rebound after fingolimod discontinuation.

Mult Scler 2018 07 30;24(8):1133-1137. Epub 2018 Apr 30.

Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1177/1352458518763095DOI Listing
July 2018

Intense immunosuppression followed by autologous haematopoietic stem cell transplantation as a therapeutic strategy in aggressive forms of multiple sclerosis.

Mult Scler 2018 03 10;24(3):245-255. Epub 2017 Nov 10.

Cell Therapy and Transfusion Medicine Unit, Careggi University Hospital, Florence, Italy.

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http://dx.doi.org/10.1177/1352458517742532DOI Listing
March 2018

Teriflunomide treatment reduces B cells in patients with MS.

Neurol Neuroimmunol Neuroinflamm 2017 Nov 23;4(6):e403. Epub 2017 Oct 23.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Unit (I.G., A.L., F.B., G.M., N.K.d.R., A.U.), and Center of Excellence for Biomedical Research (CEBR) (F.I., A.L., G.M., A.U.), University of Genoa, Italy; Ospedale Policlinico San Martino-IRCCS (A.L., G.M., A.U.), Genoa, Italy; and Rehabilitation Unit (C.S.), Centro di Recupero e Rieducazione Funzionale, M.L. Novarese, Moncrivello, Italy.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656406PMC
November 2017

NEDA status in highly active MS can be more easily obtained with autologous hematopoietic stem cell transplantation than other drugs.

Mult Scler 2017 Feb 11;23(2):201-204. Epub 2016 Jul 11.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova and IRCCS AOU San Martino-IST, Genova, Italy.

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http://dx.doi.org/10.1177/1352458516645670DOI Listing
February 2017

In vitro VLA-4 blockade results in an impaired NK cell-mediated immune surveillance against melanoma.

Immunol Lett 2017 01 2;181:109-115. Epub 2016 Dec 2.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Unit, University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Universitaria San Martino - IST, Genoa, Italy.

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http://dx.doi.org/10.1016/j.imlet.2016.11.015DOI Listing
January 2017

Autologous hematopoietic stem cell transplantation in multiple sclerosis: 20 years of experience.

Neurol Sci 2016 Jun 12;37(6):857-65. Epub 2016 Apr 12.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova and IRCCS AOU San Martino IST, Largo Paolo Daneo 3, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s10072-016-2564-3DOI Listing
June 2016

Alternative Splicing in the Human PMP22 Gene: Implications in CMT1A Neuropathy.

Hum Mutat 2016 Jan 5;37(1):98-109. Epub 2015 Nov 5.

Department of Neurosciences, Rehabilitation Ophthalmology, Genetics and Maternal-Infantile Sciences (DINOGMI) and CEBR, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1002/humu.22921DOI Listing
January 2016

Human mesenchymal stem cells target adhesion molecules and receptors involved in T cell extravasation.

Stem Cell Res Ther 2015 Dec 10;6:245. Epub 2015 Dec 10.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132, Genova, Italy.

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http://dx.doi.org/10.1186/s13287-015-0222-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676115PMC
December 2015

Low intensity lympho-ablative regimen followed by autologous hematopoietic stem cell transplantation in severe forms of multiple sclerosis: A MRI-based clinical study.

Mult Scler 2015 Oct 12;21(11):1423-30. Epub 2015 Jan 12.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health; University of Genova; Italy/Department of Health Sciences, University of Genova, Italy

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http://dx.doi.org/10.1177/1352458514564484DOI Listing
October 2015

Cingulum bundle alterations underlie subjective fatigue in multiple sclerosis.

Mult Scler 2015 Apr 21;21(4):442-7. Epub 2014 Aug 21.

Magnetic Resonance Research Centre on Nervous System Diseases, University of Genoa/San Martino University Hospital/ University of Genoa, Genoa, Italy

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http://dx.doi.org/10.1177/1352458514546791DOI Listing
April 2015

Isolated cognitive relapses in multiple sclerosis.

J Neurol Neurosurg Psychiatry 2014 Sep 31;85(9):1035-7. Epub 2014 Mar 31.

Magnetic Resonance Research Centre on Nervous System Diseases, University of Genoa, Genoa, Italy Department of Diagnostic and Interventional Neuroradiology, San Martino University Hospital, Genoa, Italy Department of Health Sciences, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1136/jnnp-2013-307275DOI Listing
September 2014

Genetic burden of common variants in progressive and bout-onset multiple sclerosis.

Mult Scler 2014 06 25;20(7):802-11. Epub 2013 Nov 25.

Laboratory of Genetics of Neurological Complex Disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Italy Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Italy

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http://dx.doi.org/10.1177/1352458513512707DOI Listing
June 2014

The FIG4 gene does not play a major role in causing ALS in Italian patients.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Apr 22;14(3):228-9. Epub 2013 Jan 22.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genova, Genova, Italy.

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http://dx.doi.org/10.3109/21678421.2012.760605DOI Listing
April 2013

Reward responsiveness and fatigue in multiple sclerosis.

Mult Scler 2013 Feb 21;19(2):233-40. Epub 2012 Jun 21.

University of Genoa, Italy.

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http://dx.doi.org/10.1177/1352458512451509DOI Listing
February 2013

Mesenchymal stem cells shape microglia effector functions through the release of CX3CL1.

Stem Cells 2012 Sep;30(9):2044-53

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1002/stem.1174DOI Listing
September 2012

Fast course ALS presenting with vocal cord paralysis: clinical features, bioinformatic and modelling analysis of the novel SOD1 Gly147Ser mutation.

Amyotroph Lateral Scler 2012 Jan 19;13(1):144-8. Epub 2011 Sep 19.

Department of Biology and Genetics, University of Genoa and U.O.C. Medical Genetics of Azienda Ospedaliera Universitaria S. Martino di Genova, Genoa, Italy.

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http://dx.doi.org/10.3109/17482968.2011.614254DOI Listing
January 2012

A novel hypothesis about mechanisms affecting conduction velocity of central myelinated fibers.

Neurochem Res 2011 Oct 8;36(10):1732-9. Epub 2011 May 8.

Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Via De Toni 5, 16132 Genova, Italy.

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http://dx.doi.org/10.1007/s11064-011-0488-0DOI Listing
October 2011

Mesenchymal stem cells for multiple sclerosis: does neural differentiation really matter?

Curr Stem Cell Res Ther 2011 Mar;6(1):69-72

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy.

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http://dx.doi.org/10.2174/157488811794480744DOI Listing
March 2011

Stem cell transplantation in multiple sclerosis.

Curr Opin Neurol 2010 Jun;23(3):218-25

Department of Neurosciences, Ophthalmology and Genetics, Italy.

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http://dx.doi.org/10.1097/WCO.0b013e328338b7edDOI Listing
June 2010

Autologous haematopoietic stem-cell transplantation in multiple sclerosis: benefits and risks.

Neurol Sci 2009 Oct;30 Suppl 2:S175-7

Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Genoa, Italy.

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http://dx.doi.org/10.1007/s10072-009-0144-5DOI Listing
October 2009

Evidence for aerobic ATP synthesis in isolated myelin vesicles.

Int J Biochem Cell Biol 2009 Jul 22;41(7):1581-91. Epub 2009 Jan 22.

Biology Department, University of Genova, Faculty of Sciences MFN, Viale Benedetto XV, Genoa, Italy.

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http://dx.doi.org/10.1016/j.biocel.2009.01.009DOI Listing
July 2009

Magnetic resonance imaging in patients implanted with Ex-PRESS stainless steel glaucoma drainage microdevice.

Am J Ophthalmol 2009 May 20;147(5):907-11, 911.e1. Epub 2009 Feb 20.

Centro di Ricerca Clinica e Laboratorio per il Glaucoma e la Cornea, Clinica Oculistica, Di.N.O.G., University of Genova, Genova, Italy.

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http://dx.doi.org/10.1016/j.ajo.2008.12.011DOI Listing
May 2009

Impaired expression of ciliary neurotrophic factor in Charcot-Marie-Tooth type 1A neuropathy.

J Neuropathol Exp Neurol 2009 May;68(5):441-55

Department of Neurosciences, Ophthalmology and Genetics, Center of Excellence for Biomedical Research, University of Genoa, Italy.

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http://dx.doi.org/10.1097/NEN.0b013e31819fa6baDOI Listing
May 2009

Further data on autologous haemopoietic stem cell transplantation in multiple sclerosis.

Lancet Neurol 2009 Mar 29;8(3):219-21. Epub 2009 Jan 29.

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http://dx.doi.org/10.1016/S1474-4422(09)70018-3DOI Listing
March 2009

Detection of motor cortex thinning and corticospinal tract involvement by quantitative MRI in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2009 Feb;10(1):47-52

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy.

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http://www.tandfonline.com/doi/full/10.1080/1748296080226753
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http://dx.doi.org/10.1080/17482960802267530DOI Listing
February 2009

Is there a role for mesenchymal stem cells in autoimmune diseases?

Autoimmunity 2008 Dec;41(8):592-5

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1080/08916930802200166DOI Listing
December 2008

Symptomatic therapies in multiple sclerosis. Introduction.

Neurol Sci 2008 Dec;29 Suppl 4:S347

Department of Neurology, ASL 3 Genovese, Genova, Italy.

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http://dx.doi.org/10.1007/s10072-008-1040-0DOI Listing
December 2008

Autologous haematopoietic stem-cell transplantation in multiple sclerosis.

Lancet Neurol 2008 Jul;7(7):626-36

Department of Neuroscience, Ophthalmology, and Genetics, and Centre of Excellence for Biomedical Research, San Martino Hospital, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1016/S1474-4422(08)70138-8DOI Listing
July 2008

Human mesenchymal stem cells promote survival of T cells in a quiescent state.

Stem Cells 2007 Jul 29;25(7):1753-60. Epub 2007 Mar 29.

Neuroimmunology Unit, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132 Genoa, Italy.

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http://doi.wiley.com/10.1634/stemcells.2007-0068
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http://dx.doi.org/10.1634/stemcells.2007-0068DOI Listing
July 2007

Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis.

Ann Neurol 2007 Mar;61(3):219-27

Neuroimmunology Unit, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genova, Italy.

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http://dx.doi.org/10.1002/ana.21076DOI Listing
March 2007

Mechanisms of the adaptive immune response inside the central nervous system during inflammatory and autoimmune diseases.

Pharmacol Ther 2006 Sep 26;111(3):555-66. Epub 2006 Jan 26.

Neuroimmunology Unit, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy.

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http://dx.doi.org/10.1016/j.pharmthera.2005.11.007DOI Listing
September 2006

Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease.

Eur J Neurosci 2006 Mar;23(6):1445-52

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy, Via De Toni, 5, 16132, Genoa, Italy.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04666.xDOI Listing
March 2006

Stem cells in inflammatory demyelinating disorders: a dual role for immunosuppression and neuroprotection.

Expert Opin Biol Ther 2006 Jan;6(1):17-22

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132 Genoa, Italy.

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http://www.tandfonline.com/doi/full/10.1517/14712598.6.1.17
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http://dx.doi.org/10.1517/14712598.6.1.17DOI Listing
January 2006

Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy.

Blood 2005 Sep 19;106(5):1755-61. Epub 2005 May 19.

Department of Neurosciences Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132-Genoa, Italy.

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http://dx.doi.org/10.1182/blood-2005-04-1496DOI Listing
September 2005

Experimental Charcot-Marie-Tooth type 1A: a cDNA microarrays analysis.

Mol Cell Neurosci 2005 Apr;28(4):703-14

Department of Neurosciences, Ophthalmology and Genetics, University of Genova, Italy, via De Toni 5, 16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.mcn.2004.11.016DOI Listing
April 2005

Computer-aided retraining of memory and attention in people with multiple sclerosis: a randomized, double-blind controlled trial.

J Neurol Sci 2004 Jul;222(1-2):99-104

Laboratory of Epidemiology, National Neurological Institute C. Besta, via Celoria 11, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.jns.2004.04.027DOI Listing
July 2004

Maintenance of B lymphocyte-related clones in the cerebrospinal fluid of multiple sclerosis patients.

Eur J Immunol 2003 Dec;33(12):3433-8

U.O. Oncologia Medica C, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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http://dx.doi.org/10.1002/eji.200324144DOI Listing
December 2003

Safety of the long-time monthly triple dose of a Gd-based contrast agent.

Eur Radiol 2003 Dec;13 Suppl 4:L243-4

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December 2003

Safety of the long-time monthly triple dose of a Gd-based contrast agent.

Eur Radiol 2003 Dec 26;13 Suppl 6:L243-4. Epub 2003 Mar 26.

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http://dx.doi.org/10.1007/s00330-003-1830-yDOI Listing
December 2003