Publications by authors named "Gianluca Damonte"

100Publications

The Remarkable Antioxidant and Anti-Inflammatory Potential of the Extracts of the Brown Alga var. .

Mar Drugs 2020 Dec 23;19(1). Epub 2020 Dec 23.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.

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December 2020

Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays.

Eur J Med Chem 2020 Dec 12;208:112833. Epub 2020 Sep 12.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132, Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 9, 16132, Genoa, Italy. Electronic address:

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December 2020

New acetylenic metabolites from the toxic mushroom .

Nat Prod Res 2020 Jun 15:1-8. Epub 2020 Jun 15.

Faculty of Science, Department of Medical Analysis, Tishk International University, Erbil, Iraq.

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June 2020

Protective effects of extracts from Ephedra foeminea Forssk fruits against oxidative injury in human endothelial cells.

J Ethnopharmacol 2020 Oct 16;260:112976. Epub 2020 May 16.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genova, Corso Europa 26, 16132, Genova, Italy. Electronic address:

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October 2020

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as potential potentiators of the chloride transport defect in cystic fibrosis.

Med Chem 2020 Mar 5. Epub 2020 Mar 5.

University of Genoa, Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research (CEBR), Viale Benedetto XV 1. Italy.

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March 2020

It's Only a Part of the Story: Analytical Investigation of the Inks and Dyes Used in the .

Molecules 2019 Jun 12;24(12). Epub 2019 Jun 12.

Dipartimento di Scienze e Innovazione Tecnologica, Università degli Studi del Piemonte Orientale, viale T. Michel, 11-15121 Alessandria, Italy.

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June 2019

Antisteatotic and antioxidant activities of Thymbra spicata L. extracts in hepatic and endothelial cells as in vitro models of non-alcoholic fatty liver disease.

J Ethnopharmacol 2019 Jul 25;239:111919. Epub 2019 Apr 25.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genova, Corso Europa 26, 16132, Genova, Italy. Electronic address:

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July 2019

Elicited ROS Scavenging Activity, Photoprotective, and Wound-Healing Properties of Collagen-Derived Peptides from the Marine Sponge .

Mar Drugs 2018 Nov 23;16(12). Epub 2018 Nov 23.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.

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November 2018

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

Eur J Med Chem 2018 Jan 8;144:179-200. Epub 2017 Dec 8.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 9, 16132 Genoa, Italy. Electronic address:

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January 2018

Di-acetyl creatine ethyl ester, a new creatine derivative for the possible treatment of creatine transporter deficiency.

Neurosci Lett 2018 02 8;665:217-223. Epub 2017 Dec 8.

Department of Neuroscience, Ophthalmology, Genetics, Maternal-Infantile Sciences (DINOGMI), University of Genova, Largo Paolo Daneo 3, 16132 Genova, Italy; Ospedale Policlinico San Martino, Genova, Italy. Electronic address:

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February 2018

A Novel Method to Synthesize Phosphocreatine and Phosphocreatine Prodrugs.

Med Chem 2018 ;14(4):387-393

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.

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August 2018

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

Bioorg Med Chem 2017 10 19;25(20):5849-5858. Epub 2017 Sep 19.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy. Electronic address:

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October 2017

Antiproliferative hydroxy-fatty acids from the fodder legume Stylosanthes guianensis.

J Pharm Biomed Anal 2017 Jul 17;141:157-164. Epub 2017 Apr 17.

Department of Earth, Environment and Life Sciences, University of Genova, Corso Europa 26, 16132 Genova, Italy.

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July 2017

The rare sugar -acetylated viosamine is a major component of Mimivirus fibers.

J Biol Chem 2017 05 17;292(18):7385-7394. Epub 2017 Mar 17.

From the Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genova, 16126 Genova, Italy,

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May 2017

Effects on Energy Metabolism of Two Guanidine Molecules, (Boc) -Creatine and Metformin.

J Cell Biochem 2017 09 13;118(9):2700-2711. Epub 2017 Feb 13.

Department of Neuroscience, Ophthalmology, Genetics, Maternal-Infantile Sciences, University of Genova, Largo Paolo Daneo 3, Genova 16132, Italy.

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September 2017

From DNA damage to functional changes of the trabecular meshwork in aging and glaucoma.

Ageing Res Rev 2016 08 27;29:26-41. Epub 2016 May 27.

Mutagenesis Unit, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Department of Health Sciences, University of Genoa, Via A. Pastore 1, Genoa I-16132, Italy.

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August 2016

The Outflow Pathway: A Tissue With Morphological and Functional Unity.

J Cell Physiol 2016 09 8;231(9):1876-93. Epub 2016 Feb 8.

Department of Health Sciences, Mutagenesis Unit, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, University of Genoa, Genoa, Italy.

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September 2016

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

Eur J Med Chem 2015 Jun 28;99:14-35. Epub 2015 May 28.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy. Electronic address:

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June 2015

Pichia pastoris production of a prolyl 4-hydroxylase derived from Chondrosia reniformis sponge: A new biotechnological tool for the recombinant production of marine collagen.

J Biotechnol 2015 Aug 27;208:28-36. Epub 2015 May 27.

Department of Earth, Environment and Life Sciences, University of Genova, Via Pastore 3, 16132, Genova, Italy; Centre of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 5, 16132, Genova, Italy.

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August 2015

Susceptibility of Vibrio aestuarianus 01/032 to the antibacterial activity of Mytilus haemolymph: identification of a serum opsonin involved in mannose-sensitive interactions.

Environ Microbiol 2015 Nov 27;17(11):4271-9. Epub 2015 Feb 27.

Department of Hearth, Environmental and Life Sciences (DISTAV), University of Genova, Corso Europa 26, 16132, Genova, Italy.

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November 2015

Synthesis, structural characterization and effect on human granulocyte intracellular cAMP levels of abscisic acid analogs.

Bioorg Med Chem 2015 Jan 27;23(1):22-32. Epub 2014 Nov 27.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy. Electronic address:

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January 2015

Giant virus Megavirus chilensis encodes the biosynthetic pathway for uncommon acetamido sugars.

J Biol Chem 2014 Aug 17;289(35):24428-39. Epub 2014 Jul 17.

From the Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV,1 16132 Genova, Italy,

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August 2014

3,5-diiodo-L-thyronine modifies the lipid droplet composition in a model of hepatosteatosis.

Cell Physiol Biochem 2014 5;33(2):344-56. Epub 2014 Feb 5.

Dipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università degli Studi di Genova, Genova, Italy.

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October 2014

A PNA-mediated clamping PCR for routine detection of KRAS mutations in colorectal carcinoma.

Int J Biol Markers 2014 Mar 24;29(1):e55-61. Epub 2014 Mar 24.

Laboratory Cancer Genetics and Translational Oncology, S. Croce General Hospital, Cuneo - Italy.

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March 2014

Effects of amide creatine derivatives in brain hippocampal slices, and their possible usefulness for curing creatine transporter deficiency.

Neurochem Res 2014 Jan 12;39(1):37-45. Epub 2013 Nov 12.

Department of Neuroscience, Ophthalmology, Genetics, Maternal-Infantile Sciences, University of Genova, Largo Paolo Daneo 3, 16132, Genoa, Italy.

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January 2014

A new method to synthesize creatine derivatives.

Amino Acids 2013 Oct 7;45(4):821-33. Epub 2013 Jun 7.

Department of Neuroscience, Ophthalmology, Genetics, Maternal-Infantile Sciences, University of Genova, Largo Paolo Daneo 3, 16132, Genoa, Italy.

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October 2013

Complement C3f serum levels may predict breast cancer risk in women with gross cystic disease of the breast.

J Proteomics 2013 Jun 30;85:44-52. Epub 2013 Apr 30.

Biopolymers and Proteomics Unit, IRCCS AOU San Martino-IST, San Martino University Hospital and National Cancer Research Institute, Genoa, Italy.

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June 2013

Giant DNA virus mimivirus encodes pathway for biosynthesis of unusual sugar 4-amino-4,6-dideoxy-D-glucose (Viosamine).

J Biol Chem 2012 Jan 8;287(5):3009-18. Epub 2011 Dec 8.

Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV/1, 16132 Genova, Italy.

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January 2012

A hemolytic peptide from the mycophilic fungus Sepedonium chrysospermum (Bull.) Fr.

Appl Microbiol Biotechnol 2012 May 13;94(4):987-94. Epub 2011 Nov 13.

Mycology Laboratory, Department for the Study of Territory and its Resources (DIP.TE.RIS), Polo Botanico Hanbury, University of Genoa, Corso Dogali 1M Genoa, Genoa, Italy.

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May 2012

Autocrine abscisic acid plays a key role in quartz-induced macrophage activation.

FASEB J 2012 Mar 31;26(3):1261-71. Epub 2011 Oct 31.

DIMES, Section of Biochemistry, University of Genova, Viale Benedetto XV, 1 16132 Genova, Italy.

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March 2012

Phytotoxic clerodane diterpenes from Salvia miniata Fernald (Lamiaceae).

Phytochemistry 2011 Feb 2;72(2-3):265-75. Epub 2010 Dec 2.

Dipartimento di Chimica e Tecnologie Farmaceutiche e Alimentari, Università di Genova, Genova, Italy.

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February 2011

Achievements and perspectives of top-down proteomics.

Proteomics 2010 Oct;10(20):3566-76

Advanced Biotechnology Center, Largo Rosanna Benzi, Genova, Italy.

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October 2010

Phytotoxic activity of Salvia x jamensis.

Nat Prod Commun 2009 Dec;4(12):1621-30

Dipartimento di Chimica e Tecnologie Farmaceutiche e Alimentari, University of Genoa, Genoa, Italy.

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December 2009

HPLC and MS analysis for the identification and characterisation of peptides presented in the context of the non-classical human leukocytes antigen (HLA) class I molecule HLA-E.

Curr Pharm Des 2009 ;15(28):3325-35

Department of Experimental Medicine, Biochemistry section c/o Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.

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January 2010

Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis.

J Biol Chem 2009 Jun 30;284(26):17808-18. Epub 2009 Mar 30.

Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genova, and Vascular and Endovascular Surgery Unit, San Martino Hospital, Viale Benedetto XV 1, 16132 Genova, Italy.

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June 2009

Top-down proteomics with a quadrupole time-of-flight mass spectrometer and collision-induced dissociation.

Rapid Commun Mass Spectrom 2009 Mar;23(5):661-6

Centro Biotecnologie Avanzate, Largo Rosanna Benzi 10, 16132 Genova, Italy.

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March 2009

Taxanes from Shells and Leaves of Corylus avellana.

J Nat Prod 2008 Jan 29;71(1):58-60. Epub 2007 Dec 29.

Department of Translational Oncology, National Institute for Cancer Research, IST, Genova, Italy.

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January 2008

Electrospray ionization ion trap multiple-stage mass spectrometric fragmentation pathways of leucine and isoleucine: an ab initio computational study.

Rapid Commun Mass Spectrom 2007 ;21(19):3180-4

Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 7 Genova, Italy.

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November 2007

Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger.

Proc Natl Acad Sci U S A 2007 Apr 26;104(14):5759-64. Epub 2007 Mar 26.

Department of Experimental Medicine, Section of Biochemistry, University of Genova, Viale Benedetto XV/1, 16132 Genoa, Italy.

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April 2007

In vitro cell cultures obtained from different explants of Corylus avellana produce Taxol and taxanes.

BMC Biotechnol 2006 Dec 6;6:45. Epub 2006 Dec 6.

Laboratory of Plant and Pharmaceutical Biotechnology, Advanced Biotechnology Center (ABC), Largo R. Benzi, 10, 16132 Genova, Italy.

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December 2006

How to discriminate between leucine and isoleucine by low energy ESI-TRAP MSn.

J Am Soc Mass Spectrom 2007 Jan 28;18(1):57-63. Epub 2006 Sep 28.

Department of Experimental Medicine-Biochemistry Section and Center of Excellence for Biomedical Research (DIMES), University of Genoa, Genoa, Italy.

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January 2007

Identification of a new truncated form and deamidation products of fibrinopeptide B released by thrombin from human fibrinogen.

Thromb Haemost 2006 Sep;96(3):302-8

S.S. Proteomica, Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, 10, I-16132 Genova, Italy.

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September 2006

High throughput HPLC-ESI-MS method for the quantitation of dexamethasone in blood plasma.

J Pharm Biomed Anal 2007 Jan 2;43(1):376-80. Epub 2006 Aug 2.

Dipartimeto di Medicina Sperimentale, Sezione di Biochimica e Centro di Eccellenza per la Ricerca Biomedica, Università di Genova, Viale Benedetto XV 5, 16132 Genova, Italy.

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January 2007

Matrix-assisted laser desorption/ionization mass spectrometry of taxanes.

Rapid Commun Mass Spectrom 2005 ;19(23):3531-8

Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV 7, 16132 Genova, Italy.

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January 2006

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells.

Proc Natl Acad Sci U S A 2005 Oct 19;102(41):14509-14. Epub 2005 Sep 19.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.

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October 2005

Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide.

Org Biomol Chem 2005 Jan 23;3(1):97-106. Epub 2004 Nov 23.

Department of Chemistry and Industrial Chemistry, via Dodecaneso 31, 16146, Genova, Italy.

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January 2005

Pituitary adenylate cyclase-activating polypeptide in the brain, spinal cord and sensory organs of the zebrafish, Danio rerio, during development.

Brain Res Dev Brain Res 2004 Jul;151(1-2):169-85

Department of Experimental Biology, Section of Development Biology, University of Genova, V.le Benedetto XV, 16132 Genova, Italy.

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July 2004

Paramecium bursaria Chlorella virus 1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose.

J Biol Chem 2003 Jun 4;278(24):21559-65. Epub 2003 Apr 4.

Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.

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June 2003

Pyroglutamate-modified amyloid beta-peptides--AbetaN3(pE)--strongly affect cultured neuron and astrocyte survival.

J Neurochem 2002 Sep;82(6):1480-9

Pharmacology and Neuroscience National Cancer Research Institute - IST c/o Advanced Biotechnology Center- and Section of Pharmacology, Department of Oncology Biology and Genetics, University of Genova, Italy.

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September 2002