Gianfranco Alpini

Gianfranco Alpini

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Gianfranco Alpini

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Fructose Promotion of Intestinal and Liver Injury: A Sugar by Any Other Name That Isn't So Sweet.

Hepatology 2019 Jul 5. Epub 2019 Jul 5.

Indiana University School of Medicine, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Indianapolis, Indiana.

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http://dx.doi.org/10.1002/hep.30843DOI Listing
July 2019

Hepatitis C Virus Infection and Cholangiocarcinoma: An Insight into Epidemiologic Evidences and Hypothetical Mechanisms of Oncogenesis.

Am J Pathol 2019 Jun 4;189(6):1122-1132. Epub 2019 Apr 4.

Baylor Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, Texas; Division of Research, Central Texas Veterans Health Care System, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.01.018DOI Listing
June 2019

Preclinical insights into cholangiopathies: disease modeling and emerging therapeutic targets.

Expert Opin Ther Targets 2019 Jun 22;23(6):461-472. Epub 2019 Apr 22.

a Indiana Center for Liver Research, Division of Gastroenterology & Hepatology, Department of Medicine , Indiana University School of Medicine , Indianapolis , IN , USA.

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http://dx.doi.org/10.1080/14728222.2019.1608950DOI Listing
June 2019

FXR deficiency and alcoholic liver disease: Tissue is the issue.

Dig Liver Dis 2019 04 7;51(4):577-578. Epub 2019 Feb 7.

Division of Gastroenterology and Hepatology, University of South Dakota Sanford School of Medicine, Transplant Hepatologist, Avera McKennan University Health Center and Transplant Institute, Chief Clinical Research Affairs, Avera Transplant Institute and Human Genetics Research Institute, 1315 S Cliff Ave, Plaza 3 Suite 1200, Sioux Falls, SD 57105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.01.014DOI Listing
April 2019

Dual Role of Bile Acids on the Biliary Epithelium: Friend or Foe?

Int J Mol Sci 2019 Apr 16;20(8). Epub 2019 Apr 16.

Richard L. Roudebush VA Medical Center and Indiana University, Gastroenterology, Medicine 1481 W 10th street, Dedication Wing⁻Room C-7151, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.3390/ijms20081869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514722PMC
April 2019

Sphingosine lipid signaling in alcoholic liver injury.

Dig Liver Dis 2019 Apr 25. Epub 2019 Apr 25.

Indiana Center for Liver Research, Richard L. Roudebush VA Medical Center, Division of Gastroenterology & Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.04.002DOI Listing
April 2019

Hepatocyte-specific and extra-hepatocyte actions of perilipin-2 during fatty liver disease: benefits of being extra.

J Physiol 2019 Mar 29;597(6):1431-1432. Epub 2019 Jan 29.

Research, Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA.

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http://dx.doi.org/10.1113/JP277539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418740PMC
March 2019

Reply.

Hepatology 2019 Mar 26. Epub 2019 Mar 26.

Indiana Center for Liver Research Division of Gastroenterology & Hepatology Department of Medicine, Indiana University School of Medicine Richard L. Roudebush VA Medical Center, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1002/hep.30619DOI Listing
March 2019

Ductular Reaction in Liver Diseases: Pathological Mechanisms and Translational Significances.

Hepatology 2019 Jan 27;69(1):420-430. Epub 2018 Dec 27.

Research, Central Texas Veterans Health Care System, Temple, TX.

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http://dx.doi.org/10.1002/hep.30150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324973PMC
January 2019

A luminescent future for the study of bile acid transporters.

Am J Physiol Gastrointest Liver Physiol 2018 Oct 12;315(4):G511-G513. Epub 2018 Jul 12.

Department of Research, Central Texas Veterans Health Care System, Temple, Texas.

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http://dx.doi.org/10.1152/ajpgi.00234.2018DOI Listing
October 2018

The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence.

Am J Pathol 2018 Oct 21;188(10):2264-2280. Epub 2018 Jul 21.

Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza, Rome, Italy; Department of Medicine, Sapienza, Rome, Italy; Eleonora Lorillard Spencer Cenci Foundation, Rome, Italy.

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http://dx.doi.org/10.1016/j.ajpath.2018.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168967PMC
October 2018

Biliary epithelium: A neuroendocrine compartment in cholestatic liver disease.

Clin Res Hepatol Gastroenterol 2018 09 17;42(4):296-305. Epub 2018 Apr 17.

Research, Central Texas Veterans Health Care System, College of Medicine, Temple, TX 76504, United States; Baylor Scott & White Digestive Disease Research Center, Baylor Scott & White, Baylor Scott & White Health, Temple, TX 76504, United States; Department of Medical Physiology, Texas A&M University, College of Medicine, Temple, TX 76504, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22107401183004
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http://dx.doi.org/10.1016/j.clinre.2018.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129425PMC
September 2018

Therapeutic Role of Sphingosine-1-Phosphate Receptor 2 in the Progression of Esophageal Adenocarcinoma.

Am J Pathol 2018 Sep 17;188(9):1949-1952. Epub 2018 Jul 17.

Research Service, Central Texas Veterans Health Care System, Temple, Texas; Department of Medical Physiology, Texas A&M Health Science Center, College of Medicine, Temple, Texas; Baylor Scott & White Health Digestive Disease Research Center, Baylor Scott & White Health, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.07.001DOI Listing
September 2018

Dual ablation of β- and γ-catenin: Critical regulators of junctions and their functions.

Hepatology 2018 06 19;67(6):2079-2081. Epub 2018 Apr 19.

Research, Central Texas Veterans Healthcare System, Temple, TX.

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http://dx.doi.org/10.1002/hep.29761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992007PMC
June 2018

Role of lactoferrin and its receptors on biliary epithelium.

Biometals 2018 06 17;31(3):369-379. Epub 2018 Mar 17.

Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1007/s10534-018-0094-6DOI Listing
June 2018

Mechanisms of cholangiocyte responses to injury.

Biochim Biophys Acta Mol Basis Dis 2018 04 23;1864(4 Pt B):1262-1269. Epub 2017 Jun 23.

Research, Central Texas Veterans Health Care System, Temple, TX, United States; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, United States; Department of Medicine, Texas A&M Health Science Center, College of Medicine, Temple, TX, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439173021
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http://dx.doi.org/10.1016/j.bbadis.2017.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742086PMC
April 2018

Updates on Dietary Models of Nonalcoholic Fatty Liver Disease: Current Studies and Insights.

Gene Expr 2018 03 2;18(1):5-17. Epub 2017 Nov 2.

Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.

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http://dx.doi.org/10.3727/105221617X15093707969658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860971PMC
March 2018

Knockout of l-Histidine Decarboxylase Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling.

Am J Pathol 2018 03 15;188(3):600-615. Epub 2017 Dec 15.

Department of Research, Central Texas Veterans Health Care System, Bryan, Texas; Department of Medical Physiology, Texas A&M Health Science Center, College of Medicine, Bryan, Texas; Department of Research, Baylor Scott & White Health Digestive Disease Research Center, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840487PMC
March 2018

Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury.

Am J Pathol 2017 Dec 8;187(12):2788-2798. Epub 2017 Nov 8.

Division of Research, Central Texas Veterans Healthcare System, Temple, Texas; Baylor Scott & White Health Digestive Disease Research Center, Baylor Scott & White Healthcare, Temple, Texas; Department of Internal Medicine, Texas A&M University Health Science Center College of Medicine, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.08.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718103PMC
December 2017

Impact of prevailing thiamin levels on thiamin pyrophosphate uptake in pancreatic acinar cells: do the shuttle!

Am J Physiol Gastrointest Liver Physiol 2017 11 24;313(5):G373-G375. Epub 2017 Aug 24.

Research, Central Texas Veterans Healthcare System, Temple, Texas;

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http://dx.doi.org/10.1152/ajpgi.00256.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146300PMC
November 2017

Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2 mice.

J Surg Res 2017 09 11;217:160-169. Epub 2017 May 11.

Department of Medicine, Baylor Scott & White Health and Texas A&M University Health Science Center, Temple, Texas; Baylor Scott & White Digestive Disease Research Center, Baylor Scott & White, Temple, Texas; Research, Central Texas Veterans Health Care System, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2017.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760243PMC
September 2017

Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.

Am J Pathol 2017 Jul 12;187(7):1551-1565. Epub 2017 May 12.

Department of Internal Medicine, Texas A&M Health Science Center, College of Medicine, Temple, Texas; Department of Research, Central Texas Veterans Health Care System, Temple, Texas; Baylor Scott & White Health Digestive Disease Research Center, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500827PMC
July 2017

Diagnostic and therapeutic potentials of microRNAs in cholangiopathies.

Liver Res 2017 Jun 26;1(1):34-41. Epub 2017 Apr 26.

Research, Central Texas Veterans Health Care System.

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http://dx.doi.org/10.1016/j.livres.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659325PMC
June 2017

Nicotine Promotes Cholangiocarcinoma Growth in Xenograft Mice.

Am J Pathol 2017 May 14;187(5):1093-1105. Epub 2017 Mar 14.

Department of Internal Medicine, Texas A&M Health Science Center, College of Medicine, Temple, Texas; Central Texas Veterans Health Care System, Temple, Texas; Digestive Disease Research Center, Baylor Scott & White Health, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.01.011DOI Listing
May 2017

miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation.

Am J Pathol 2017 Mar 11;187(3):570-580. Epub 2017 Jan 11.

Department of Medicine, Baylor Scott & White and Texas A&M University Health Science Center, Temple, Texas; Research Section, Central Texas Veterans Health Care System, Baylor Scott & White and Texas A&M University Health Science Center, Temple, Texas; Baylor Scott & White Digestive Disease Research Center, Baylor Scott & White and Texas A&M University Health Science Center, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389363PMC
March 2017

Inhibition of the apelin/apelin receptor axis decreases cholangiocarcinoma growth.

Cancer Lett 2017 02 26;386:179-188. Epub 2016 Nov 26.

Research, Central Texas Veterans Health Care System, Temple, TX 76504, USA; Baylor Scott & White Digestive Disease Research Center, Scott & White, Temple, TX 76504, USA; Scott & White Medical Center, Department of Medicine, Temple, TX 76508, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510601PMC
February 2017

Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages.

J Hepatol 2017 01 1;66(1):102-115. Epub 2016 Sep 1.

Center for Autoimmune Liver Diseases, Humanitas Clinical and Research Center, Rozzano, Italy; Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery, University of Milan-Bicocca, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522599PMC
January 2017

Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease.

Lab Invest 2016 11 29;96(11):1147-1155. Epub 2016 Aug 29.

Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, "Sapienza" University of Rome, Rome, Italy.

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http://dx.doi.org/10.1038/labinvest.2016.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480400PMC
November 2016

Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization.

Am J Physiol Gastrointest Liver Physiol 2016 09 26;311(3):G396-411. Epub 2016 May 26.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland;

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http://dx.doi.org/10.1152/ajpgi.00027.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076009PMC
September 2016

Pathogenesis of Kupffer Cells in Cholestatic Liver Injury.

Am J Pathol 2016 09 22;186(9):2238-47. Epub 2016 Jul 22.

Research, Central Texas Veterans Health Care System, Temple, Texas; Department of Medicine, Texas A&M Health Science Center, College of Medicine, Temple, Texas; Scott & White Digestive Disease Research Center, Scott & White, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012503PMC
September 2016

Corrigendum to "Exosomes in liver pathology".

J Hepatol 2016 Sep 18;65(3):655. Epub 2016 Jul 18.

Research, Central Texas Veterans Health Care System, USA; Department of Medicine, Texas A&M Health Science Center, College of Medicine, USA; Scott & White Digestive Disease Research Center, Scott & White, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.06.016DOI Listing
September 2016

Exosomes in liver pathology.

J Hepatol 2016 07 14;65(1):213-221. Epub 2016 Mar 14.

Research, Central Texas Veterans Health Care System, USA; Department of Medicine, Texas A&M Health Science Center, College of Medicine, USA; Scott & White Digestive Disease Research Center, Scott & White, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912847PMC
July 2016

Heat shock factor-1 knockout enhances cholesterol 7α-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis.

Cardiovasc Res 2016 07 30;111(1):74-83. Epub 2016 Apr 30.

Division of Cardiovascular Medicine, Department of Internal Medicine, Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA

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http://dx.doi.org/10.1093/cvr/cvw094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909164PMC
July 2016

miR-34a-dependent overexpression of Per1 decreases cholangiocarcinoma growth.

J Hepatol 2016 06 24;64(6):1295-304. Epub 2016 Feb 24.

Research, Central Texas Veterans Health Care System, United States; Baylor Scott & White Digestive Disease Research Center, United States; Department of Medicine, Texas A&M Health Science Center, United States; Department of Medical Physiology, Texas A&M Health Science Center, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874896PMC
June 2016

Lin28 and let-7: roles and regulation in liver diseases.

Am J Physiol Gastrointest Liver Physiol 2016 05 24;310(10):G757-65. Epub 2016 Mar 24.

Research, Central Texas Veterans Health Care System, Temple, Texas; Baylor Scott & White Digestive Disease Research Center, Scott & White Memorial Hospital, Temple, Texas; Department of Medicine, Baylor Scott & White and Texas A & M Health Science Center, Temple, Texas;

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http://dx.doi.org/10.1152/ajpgi.00080.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888551PMC
May 2016

Role of stem cells during diabetic liver injury.

J Cell Mol Med 2016 Feb 9;20(2):195-203. Epub 2015 Dec 9.

Research, Central Texas Veterans Health Care System, Temple, TX, USA.

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http://dx.doi.org/10.1111/jcmm.12723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727564PMC
February 2016

Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling.

Am J Pathol 2016 Jan 18;186(1):123-33. Epub 2015 Nov 18.

Scott & White Digestive Disease Research Center, Temple, Texas; Department of Research, Central Texas Veterans Health Care System, Temple, Texas; Department of Medicine, Scott & White Healthcare, Temple, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440150057
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http://dx.doi.org/10.1016/j.ajpath.2015.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707204PMC
January 2016

Role of Janus Kinase 3 in Predisposition to Obesity-associated Metabolic Syndrome.

J Biol Chem 2015 Dec 8;290(49):29301-12. Epub 2015 Oct 8.

From the Department of Pharmaceutical Sciences, ILR College of Pharmacy, Texas A &M University System Health Science Center, Kingsville, Texas 78363 and

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http://dx.doi.org/10.1074/jbc.M115.670331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705936PMC
December 2015

Peri-scoping the biliary tree reveals stem cell activation in peribiliary glands in primary sclerosing cholangitis.

J Hepatol 2015 Nov 26;63(5):1062-3. Epub 2015 Jul 26.

Department of Medicine and Scott & White Digestive Disease Research Center, Texas A&M HSC College of Medicine and Baylor Scott & White Healthcare, Temple, TX, United States; Research, Central Texas Veterans Health Care System, Temple, TX, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278150047
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http://dx.doi.org/10.1016/j.jhep.2015.07.015DOI Listing
November 2015

Development and functional characterization of extrahepatic cholangiocyte lines from normal rats.

Dig Liver Dis 2015 Nov 26;47(11):964-72. Epub 2015 Jul 26.

Research, Central Texas Veterans Health Care System, United States; Scott & White Digestive Disease Research Center, Academic Operations, Scott & White, United States; Department Medicine, Division Gastroenterology, S&W and Texas A&M HSC, Temple, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2015.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624466PMC
November 2015

Yes-associated protein in the liver: Regulation of hepatic development, repair, cell fate determination and tumorigenesis.

Dig Liver Dis 2015 Oct 22;47(10):826-35. Epub 2015 May 22.

Research, Central Texas Veterans Health Care System, Temple, TX, United States; Digestive Diseases Research Center, BaylorScott&White Healthcare, Temple, TX, United States; Department of Internal Medicine and Medical Physiology, Texas A&M Health Science Center, Temple, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2015.05.011DOI Listing
October 2015

Functional and structural features of cholangiocytes in health and disease.

Cell Mol Gastroenterol Hepatol 2015 Jul;1(4):368-380

Research, Central Texas Veterans Health Care System, Texas A&M University Health Science Center, Temple, TX 76504 ; Scott & White Digestive Disease Research Center, Scott & White, Texas A&M University Health Science Center, Temple, TX 76504 ; Department of Medicine, Division Gastroenterology, Texas A&M University Health Science Center, Temple, TX 76504.

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http://dx.doi.org/10.1016/j.jcmgh.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530547PMC
July 2015

Profiles of cancer stem cell subpopulations in cholangiocarcinomas.

Am J Pathol 2015 Jun 17;185(6):1724-39. Epub 2015 Apr 17.

Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy; Eleonora Lorillard Spencer-Cenci Foundation, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450332PMC
June 2015

Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms.

Am J Pathol 2015 Apr;185(4):1061-72

Department of Medicine, Texas A&M Health Science Center College of Medicine, Temple, Texas; Scott & White Digestive Disease Research Center, Texas A&M Health Science Center College of Medicine, Temple, Texas; Department of Research, Central Texas Veterans Health Care System, Texas A&M Health Science Center College of Medicine, Temple, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440150001
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http://dx.doi.org/10.1016/j.ajpath.2014.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380841PMC
April 2015

Functional role of cellular senescence in biliary injury.

Am J Pathol 2015 Mar 22;185(3):602-9. Epub 2015 Jan 22.

Department of Research, Central Texas Veterans Health Care System, Temple, Texas; Department of Medicine, Digestive Disease Research Center, Scott & White Healthcare, Texas A&M Health Science Center, College of Medicine, Baylor Scott & White Health, Temple, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.10.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348464PMC
March 2015

Bile acid signaling and biliary functions.

Acta Pharm Sin B 2015 Mar 19;5(2):123-8. Epub 2015 Feb 19.

Division Research, Central Texas Veterans Health Care System, Temple, TX 76504, USA ; Baylor Scott & White Digestive Disease Research Center, Temple, TX 76504, USA ; Department of Medicine, Texas A&M University, Temple, TX 76504, USA.

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http://dx.doi.org/10.1016/j.apsb.2015.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629225PMC
March 2015

Probiotic Bifidobacterium species: potential beneficial effects in diarrheal disorders. Focus on "Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells".

Am J Physiol Cell Physiol 2014 Dec 10;307(12):C1081-3. Epub 2014 Sep 10.

Research, Central Texas Veterans Health Care System, Temple, Texas; Scott & White Digestive Disease Research Center, Scott & White Healthcare, Temple, Texas; and Division of Gastroenterology, Department of Medicine, Texas A & M University Health Science Center, Temple, Texas

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http://dx.doi.org/10.1152/ajpcell.00300.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269664PMC
December 2014

Mouse models of liver fibrosis mimic human liver fibrosis of different etiologies.

Curr Pathobiol Rep 2014 Dec;2(4):143-153

Department of Internal Medicine, College of Medicine, Texas A&M University Health Science Center, Temple, Texas ; Scott & White Digestive Disease Research Center, Scott & White, Temple, Texas ; Research, Central Texas Veterans Health Care System, Temple, Texas.

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http://link.springer.com/10.1007/s40139-014-0050-2
Publisher Site
http://dx.doi.org/10.1007/s40139-014-0050-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226463PMC
December 2014

Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis.

Am J Physiol Gastrointest Liver Physiol 2014 Nov 11;307(9):G894-904. Epub 2014 Sep 11.

Research, Central Texas Veterans Health Care System, Temple, Texas; Baylor Scott & White Digestive Disease Research Center, Scott & White, Temple, Texas; Department of Medicine, Division Gastroenterology, Texas A&M University Health Science Center, Temple, Texas;

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http://dx.doi.org/10.1152/ajpgi.00288.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216989PMC
November 2014

Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injury.

J Biol Chem 2014 Oct 12;289(40):27526-39. Epub 2014 Aug 12.

From the Research, Central Texas Veterans Health Care System and the Department of Medicine and Scott & White Digestive Disease Research Center, Texas A&M Health Science Center College of Medicine and Scott & White Hospital, Temple, Texas 76504,

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http://dx.doi.org/10.1074/jbc.M114.602383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183793PMC
October 2014

Role of docosahexaenoic acid treatment in improving liver histology in pediatric nonalcoholic fatty liver disease.

PLoS One 2014 4;9(2):e88005. Epub 2014 Feb 4.

Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088005PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913708PMC
September 2014

Cholangiocarcinoma development: the resurgence of bile acids.

Hepatology 2014 Sep 17;60(3):795-7. Epub 2014 Jul 17.

Clinic of Gastroenterology and Hepatology, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1002/hep.27223DOI Listing
September 2014

Role of cholangiocytes in primary biliary cirrhosis.

Semin Liver Dis 2014 Aug 24;34(3):273-84. Epub 2014 Jul 24.

Clinic of Gastroenterology and Hepatology, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1055/s-0034-1383727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182310PMC
August 2014

Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline.

J Neuroinflammation 2014 Jul 10;11:121. Epub 2014 Jul 10.

Department of Internal Medicine, Texas A&M Health Science Center, College of Medicine, 1901 South 1st Street, Building 205, Temple, Texas, USA.

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http://dx.doi.org/10.1186/1742-2094-11-121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128607PMC
July 2014

Secretin stimulates biliary cell proliferation by regulating expression of microRNA 125b and microRNA let7a in mice.

Gastroenterology 2014 Jun 25;146(7):1795-808.e12. Epub 2014 Feb 25.

Research, Central Texas Veterans Health Care System, Temple, Texas; Scott & White Digestive Disease Research Center, Scott & White, Temple, Texas; Department of Medicine, Division of Gastroenterology, Texas A&M Health Science Center College of Medicine, Temple, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085140024
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http://dx.doi.org/10.1053/j.gastro.2014.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035389PMC
June 2014

Prolonged administration of secretin to normal rats increases biliary proliferation and secretin-induced ductal secretory activity.

Hepatobiliary Surg Nutr 2014 Jun;3(3):118-25

1 Department of Medicine, Division Gastroenterology, Texas A&M Health Science Center, College of Medicine, Temple, TX, USA ; 2 University of Rome Sapienza, Rome, Italy ; 3 Research, Central Texas Veterans Health Care System, TX, USA ; 4 Scott & White Digestive Disease Research Center, Scott & White, TX, USA.

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http://www.thehbsn.org/article/view/3763/4895
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http://dx.doi.org/10.3978/j.issn.2304-3881.2014.04.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073314PMC
June 2014

Molecular mechanisms of stem cell therapy in alcoholic liver disease.

Dig Liver Dis 2014 May 15;46(5):391-7. Epub 2014 Jan 15.

Research, Central Texas Veterans Health Care System, Temple, TX, USA; Department of Medicine, Scott & White Digestive Disease Research Center, Texas A&M University Health Science Center and Scott & White Healthcare, Temple, TX, USA; Academic Operations, Scott & White Hospital, Temple, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2013.11.015DOI Listing
May 2014

The functional role of microRNAs in alcoholic liver injury.

J Cell Mol Med 2014 Feb 8;18(2):197-207. Epub 2014 Jan 8.

Research, Central Texas Veterans Health Care System, Temple, TX, USA; Department of Medicine, Scott & White Digestive Disease Research Center, Texas A&M University Health Science Center and Scott & White Healthcare, Temple, TX, USA; Academic Operations, Scott & White Hospital, Temple, TX, USA.

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http://dx.doi.org/10.1111/jcmm.12223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930407PMC
February 2014

Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes.

Hepatobiliary Surg Nutr 2014 Feb;3(1):4-10

1 Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza, Rome, Italy ; 2 Eleonora Lorillard Spencer Cenci Foundation, Rome, Italy ; 3 Research, Central Texas Veterans Health Care System, 4 Scott & White Digestive Disease Research Center, Scott & White, Academic Operations, Scott & White, 5 Department of Medicine, Division Gastroenterology, Texas A&M Health Science Center, College of Medicine, Temple, TX 76504, USA.

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http://www.thehbsn.org/article/view/3330
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http://dx.doi.org/10.3978/j.issn.2304-3881.2014.01.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954993PMC
February 2014

Melatonin regulation of biliary functions.

Hepatobiliary Surg Nutr 2014 Feb;3(1):35-43

1 Research, Central Texas Veterans Health Care System, 2 Scott & White Digestive Disease Research Center, Scott & White, 3 Division of Gastroenterology, Department of Medicine, 4 Division of Research and Education, Scott & White, Texas A&M Health Science Center, College of Medicine, Temple, TX 76504, USA.

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http://www.thehbsn.org/article/view/3375
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http://dx.doi.org/10.3978/j.issn.2304-3881.2013.10.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954997PMC
February 2014

The physiological roles of secretin and its receptor.

Ann Transl Med 2013 Oct;1(3):29

1 Department of Medicine, Division Gastroenterology, 2 Research, Central Texas Veterans Health Care System, 3 Scott & White Digestive Disease Research Center, Scott & White, and Texas A&M Health Science Center, College of Medicine, Temple, TX 76504, USA ; 4 Experimental Medicine, University of L'Aquila, L'Aquila, Italy ; 5 Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, University Sapienza, Rome, Italy.

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http://dx.doi.org/10.3978/j.issn.2305-5839.2012.12.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200670PMC
October 2013

Functional role of microvesicles in gastrointestinal malignancies.

Ann Transl Med 2013 Apr;1(1)

Scott & White Digestive Disease Research Center, Scott & White Healthcare, Temple, Texas 76S04, USA ; Research Division, Central Texas Veterans Health Care System, Temple, TX, USA ; Department of Medicine, Division of Gastroenterology, Texas A&M Health Science Center, College of Medicine, Temple, TX 76S04, USA.

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http://dx.doi.org/10.3978/j.issn.2305-5839.2012.10.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890379PMC
April 2013