Giancarlo Comi

Giancarlo Comi

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Giancarlo Comi

Giancarlo Comi

Publications by authors named "Giancarlo Comi"

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Pharmacokinetics and pharmacodynamics of natalizumab in pediatric patients with RRMS.

Neurol Neuroimmunol Neuroinflamm 2019 Sep 1;6(5):e591. Epub 2019 Jul 1.

Multiple Sclerosis Study Center (A.G.), ASST Valle Olona, Gallarate Hospital (VA); Department of Neurology (G.C., L.M.), Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Department of Neurology (L.M.G.), Fondazione Istituto G. Giglio, Cefalù; Department of Neurology (C.P.), "La Sapienza" University, Rome; Biogen Italia (S.F.), Milan; and Department of Neuroscience DNS, Multiple Sclerosis Centre (P.G.), Università degli Studi di Padova, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624146PMC
September 2019

Pharmacokinetics and pharmacodynamics of natalizumab in pediatric patients with RRMS.

Neurol Neuroimmunol Neuroinflamm 2019 Sep 1;6(5). Epub 2019 Jul 1.

From the Multiple Sclerosis Study Center (A.G.), ASST Valle Olona, Gallarate Hospital (VA); Department of Neurology (G.C., L.M.), Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Department of Neurology (L.M.G.), Fondazione Istituto G. Giglio, Cefalù; Department of Neurology (C.P.), "La Sapienza" University, Rome; Biogen Italia (S.F.), Milan; and Department of Neuroscience DNS, Multiple Sclerosis Centre (P.G.), Università degli Studi di Padova, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000591DOI Listing
September 2019

Concurrence of NMOSD and ALS in a patient with hexanucleotide repeat expansions of C9orf72.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Aug 22;20(5-6):449-452. Epub 2019 Apr 22.

a Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, IRCCS San Raffaele Scientific Institute , Vita-Salute San Raffaele University , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/21678421.2019.1
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http://dx.doi.org/10.1080/21678421.2019.1604761DOI Listing
August 2019

Caesarean section and infant formula feeding are associated with an earlier age of onset of multiple sclerosis.

Mult Scler Relat Disord 2019 Aug 21;33:75-77. Epub 2019 May 21.

Department of Neurology, San Raffaele Hospital, via Olgettina 48, 20132 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2019.05.010DOI Listing
August 2019

Reply to "Serum Neurofilaments as Candidate Biomarkers of Natalizumab Progressive Multifocal Leukoencephalopathy".

Ann Neurol 2019 Aug 26;86(2):324. Epub 2019 Jun 26.

Division of Neuroscience, Institute of Experimental Neurology, San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1002/ana.25526DOI Listing
August 2019

Long-term outcomes with teriflunomide in patients with clinically isolated syndrome: Results of the TOPIC extension study.

Mult Scler Relat Disord 2019 Aug 24;33:131-138. Epub 2019 May 24.

McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, United States.

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http://dx.doi.org/10.1016/j.msard.2019.05.014DOI Listing
August 2019

Subclinical neurodegeneration in multiple sclerosis and neuromyelitis optica spectrum disorder revealed by optical coherence tomography.

Mult Scler 2019 Aug 8:1352458519861603. Epub 2019 Aug 8.

Department of Neurorehabilitation and Department of Clinical Neurophysiology, Hospital San Raffaele, Milan, Italy/ INSPE, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy/ University Vita-Salute San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1177/1352458519861603DOI Listing
August 2019

Effects of Natalizumab and Fingolimod on Clinical, Cognitive, and Magnetic Resonance Imaging Measures in Multiple Sclerosis.

Neurotherapeutics 2019 Aug 26. Epub 2019 Aug 26.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Scientific Institute, Via Olgettina, 60, Milan, 20132, Italy.

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http://dx.doi.org/10.1007/s13311-019-00781-wDOI Listing
August 2019

Loss of Circulating CD8+ CD161 T Cells in Primary Progressive Multiple Sclerosis.

Front Immunol 2019 14;10:1922. Epub 2019 Aug 14.

Division of Neuroscience, Institute of Experimental Neurology, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.3389/fimmu.2019.01922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702304PMC
August 2019

Cross-modal plasticity among sensory networks in neuromyelitis optica spectrum disorders.

Mult Scler 2019 Jun 17;25(7):968-979. Epub 2018 May 17.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518778008DOI Listing
June 2019

Semi-invasive and non-invasive recording of visual evoked potentials in mice.

Doc Ophthalmol 2019 06 6;138(3):169-179. Epub 2019 Mar 6.

University Vita-Salute San Raffaele, Via Olgettina 60, 20132, Milan, Italy.

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http://link.springer.com/10.1007/s10633-019-09680-z
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http://dx.doi.org/10.1007/s10633-019-09680-zDOI Listing
June 2019

Characterizing lymphocyte counts and infection rates with long-term teriflunomide treatment: Pooled analysis of clinical trials.

Mult Scler 2019 Jun 7:1352458519851981. Epub 2019 Jun 7.

University of Ottawa and the Ottawa Hospital Research Institute, Ottawa, ON, Canada.

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http://dx.doi.org/10.1177/1352458519851981DOI Listing
June 2019

A pharmacogenetic study implicates in the response to Interferon-β in multiple sclerosis.

Mult Scler 2019 Jun 21:1352458519851428. Epub 2019 Jun 21.

Laboratory of Human Genetics of Neurological Disorders, Institute of Experimental Neurology (INSPE), IRCCS San Raffaele Scientific Institute, Milan, Italy/Department of Biomedical Sciences for Health, University of Milan, Milan, Italy/Department of Neurology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

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http://dx.doi.org/10.1177/1352458519851428DOI Listing
June 2019

Hippocampal-related memory network in multiple sclerosis: A structural connectivity analysis.

Mult Scler 2019 May 23;25(6):801-810. Epub 2018 Apr 23.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518771838DOI Listing
May 2019

Assessing seasonal dynamics of Guillain-Barré syndrome with search engine query data.

Neurol Sci 2019 May 14;40(5):1015-1018. Epub 2019 Feb 14.

Department of Neurology, San Raffaele Scientific Institute and University Hospital, Via Olgettina 48, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s10072-019-03757-yDOI Listing
May 2019

Multispectral MRI with Dual Fluorinated Probes to Track Mononuclear Cell Activity in Mice.

Radiology 2019 May 19;291(2):351-357. Epub 2019 Mar 19.

From the Institute of Experimental Neurology (INSPE) and Experimental Imaging Center (CIS), INSPE-DiBiT2, IRCCS Ospedale San Raffaele, via Olgettina 60, Milan 20132, Italy (C.C., D.D.B., G.C., L.C.); and SupraBioNano Laboratory, Department of Chemistry, Materials, and Chemical Engineering "Giulio Natta" Politecnico di Milano, Milan, Italy (I.T., P.M., F.B.B.).

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http://dx.doi.org/10.1148/radiol.2019181073DOI Listing
May 2019

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials.

Mult Scler 2019 04 9;25(4):565-573. Epub 2018 Mar 9.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, München, Germany/German Competence Network Multiple Sclerosis (KKNMS), München, Germany/Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1177/1352458518763089DOI Listing
April 2019

The Multiple Sclerosis Care Unit.

Mult Scler 2019 Apr 23;25(5):627-636. Epub 2018 Oct 23.

Department of Neurology and Institute of Experimental Neurology, Vita-Salute San Raffaele University, San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518807082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439947PMC
April 2019

Added value of multimodal MRI to the clinical diagnosis of primary progressive aphasia variants.

Cortex 2019 Apr 8;113:58-66. Epub 2018 Dec 8.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2018.11.025DOI Listing
April 2019

Safety of cladribine tablets in the treatment of patients with multiple sclerosis: An integrated analysis.

Mult Scler Relat Disord 2019 Apr 20;29:157-167. Epub 2018 Nov 20.

Merck KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany.

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http://dx.doi.org/10.1016/j.msard.2018.11.021DOI Listing
April 2019

Cognitive reserve, cognition, and regional brain damage in MS: A 2 -year longitudinal study.

Mult Scler 2019 03 5;25(3):372-381. Epub 2018 Jan 5.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458517750767DOI Listing
March 2019

Brain and cord imaging features in neuromyelitis optica spectrum disorders.

Ann Neurol 2019 Mar 28;85(3):371-384. Epub 2019 Jan 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://doi.wiley.com/10.1002/ana.25411
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http://dx.doi.org/10.1002/ana.25411DOI Listing
March 2019

Imaging patterns of gray and white matter abnormalities associated with PASAT and SDMT performance in relapsing-remitting multiple sclerosis.

Mult Scler 2019 02 27;25(2):204-216. Epub 2017 Nov 27.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458517743091DOI Listing
February 2019

Severe disease activity in a patient with multiple sclerosis after daclizumab discontinuation.

Mult Scler Relat Disord 2019 Feb 1;28:57-59. Epub 2018 Dec 1.

Department of Neurology, San Raffaele Hospital, via Olgettina 48, 20132 Milan, Italy.

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http://dx.doi.org/10.1016/j.msard.2018.11.034DOI Listing
February 2019

Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial.

Lancet Neurol 2019 Feb 13;18(2):155-164. Epub 2018 Dec 13.

Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183040
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http://dx.doi.org/10.1016/S1474-4422(18)30406-XDOI Listing
February 2019

Prognostic value of serum neurofilaments in patients with clinically isolated syndromes.

Neurology 2019 Feb 11;92(7):e733-e741. Epub 2019 Jan 11.

From the Department of Neurology (G.D.C., V.M., F.S., L.M., B.C., M.R., G.C.), Experimental Neurophysiology Research Unit (L.L.), and Neuroimmunology Research Unit (R.F.), San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000006902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382362PMC
February 2019

Structural connectivity in multiple sclerosis and modeling of disconnection.

Mult Scler 2019 Jan 9:1352458518820759. Epub 2019 Jan 9.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518820759DOI Listing
January 2019

Imaging correlates of hand motor performance in multiple sclerosis: A multiparametric structural and functional MRI study.

Mult Scler 2019 Jan 18:1352458518822145. Epub 2019 Jan 18.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/ Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518822145DOI Listing
January 2019

Letter to the Editor Regarding: A Comprehensive Review on Copemyl.

Neurol Ther 2018 Dec 10;7(2):385-390. Epub 2018 Nov 10.

Neurology and Neurorehabilitation Units, IRCCS Neuromed, Pozzilli, IS, Italy.

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http://link.springer.com/10.1007/s40120-018-0115-y
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http://dx.doi.org/10.1007/s40120-018-0115-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283790PMC
December 2018

NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.

Mult Scler 2018 10 9;24(11):1507-1510. Epub 2017 Nov 9.

Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat) and Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/1352458517739137DOI Listing
October 2018

Visual Evoked Potentials as a Biomarker in Multiple Sclerosis and Associated Optic Neuritis.

J Neuroophthalmol 2018 Sep;38(3):350-357

Department of Neurology, Institute of Experimental Neurology-INSPE, San Raffaele University Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/WNO.0000000000000704DOI Listing
September 2018

Abnormal functional connectivity of thalamic sub-regions contributes to fatigue in multiple sclerosis.

Mult Scler 2018 08 28;24(9):1183-1195. Epub 2017 Jun 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://journals.sagepub.com/doi/10.1177/1352458517717807
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http://dx.doi.org/10.1177/1352458517717807DOI Listing
August 2018

Functional and structural plasticity following action observation training in multiple sclerosis.

Mult Scler 2018 Aug 7:1352458518792771. Epub 2018 Aug 7.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518792771DOI Listing
August 2018

Cervical Cord T1-weighted Hypointense Lesions at MR Imaging in Multiple Sclerosis: Relationship to Cord Atrophy and Disability.

Radiology 2018 Jul 17;288(1):234-244. Epub 2018 Apr 17.

From the Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience (P.V., M.A., P.P., R.M., M.F., M.A.R.), Department of Neurology (P.P., R.M., G.C., M.F., M.A.R.), and Department of Neuroradiology (A.F.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, Italy.

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http://dx.doi.org/10.1148/radiol.2018172311DOI Listing
July 2018

Can pharmacological manipulation of LTP favor the effects of motor rehabilitation in multiple sclerosis?

Mult Scler 2018 06 24;24(7):902-907. Epub 2017 Jul 24.

Neurology and Neurorehabilitation Units, IRCCS Neuromed, Pozzilli (IS), Italy/Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1177/1352458517721358DOI Listing
June 2018

Visual evoked potentials can be reliably recorded using noninvasive epidermal electrodes in the anesthetized rat.

Doc Ophthalmol 2018 Jun 5;136(3):165-175. Epub 2018 Apr 5.

Department of Neurology and Institute of Experimental Neurology (INSPE) - IRCCS-San Raffaele Hospital, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s10633-018-9630-5DOI Listing
June 2018

Pediatric sporadic hemiplegic migraine (ATP1A2 gene): a case report and brief literature review.

Neurol Sci 2018 Jun;39(Suppl 1):69-71

Department of Neurology and Neurophysiology, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1007/s10072-018-3405-3DOI Listing
June 2018

Changes in functional and structural brain connectome along the Alzheimer's disease continuum.

Mol Psychiatry 2018 May 9. Epub 2018 May 9.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1038/s41380-018-0067-8DOI Listing
May 2018

Multimodal structural MRI in the diagnosis of motor neuron diseases.

Neuroimage Clin 2017 2;16:240-247. Epub 2017 Aug 2.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/j.nicl.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545829PMC
April 2018

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: II: Maternal risks.

Neurology 2018 03 7;90(10):e832-e839. Epub 2018 Feb 7.

From IRCCS Don Gnocchi Foundation (E.P.), Florence; Scientific Institute University Vita-Salute San Raffaele (L.M., V.M., G.C.), Milan; Multiple Sclerosis Study Center (P.A., A.G., M.Z.), ASST Valle Olona, Gallarate Hospital (VA); Department of Neurosciences, Reproductive and Odontostomatological Sciences (R.L., V.B.M.), Federico II University of Naples; Department of Neurosciences (F.R., P.G.), Multiple Sclerosis Centre-Veneto Region (CeSMuV), University Hospital of Padova; Department of Neurology (C.T., D.P., M.T.), University of Bari; Department of Neurology and Psychiatry (C.P., L.D.G.), "La Sapienza" University, Rome; Department of Neurology (P.C.), University of Torino; Department of Medical Sciences and Public Health (E.C., M.G.M.), University of Cagliari; Department of Neurology (C.S.), ASL3 Genovese; Department of Neurology (A.U., A.L.), University of Genova; and Department of NEUROFARBA (L.P., M.G., M.P.A.), University of Florence, Italy.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005068DOI Listing
March 2018

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: I: Fetal risks.

Neurology 2018 03 7;90(10):e823-e831. Epub 2018 Feb 7.

From IRCCS Don Gnocchi Foundation (E.P.), Florence; Multiple Sclerosis Study Center (P.A., A.G., M.Z.), ASST Valle Olona, Gallarate Hospital (VA); Scientific Institute University Vita-Salute San Raffaele (L.M., V.M., G.C.), Milan; Department of Neurosciences, Reproductive and Odontostomatological Sciences (R.L., V.B.M.), Federico II University of Naples; Department of Neurosciences (F.R., P.G.), Multiple Sclerosis Centre-Veneto Region (CeSMuV), University Hospital of Padova; Department of Neurology (C.T., D.P., M.T.), University of Bari; Department of Neurology and Psychiatry (C.P., L.D.G.), "La Sapienza" University, Rome; Department of Neurology (P.C.), University of Torino; Department of Medical Sciences and Public Health (E.C., M.G.M.), University of Cagliari; Department of Neurology (F.P.), University of Catania; Department of Neurology (C.S.), ASL3 Genovese; Multiple Sclerosis Center (P.B.), IRCCS Neuromed, Pozzilli; Department of Neurology (A.U., A.L.), University of Genova; and Department of NEUROFARBA (L.P., M.G., M.P.A.), University of Florence, Italy.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005067DOI Listing
March 2018

Bi-hemispheric repetitive transcranial magnetic stimulation for upper limb motor recovery in chronic stroke: A feasibility study.

Brain Stimul 2018 Jul - Aug;11(4):932-934. Epub 2018 Mar 15.

Neurological Department and Experimental Neurophysiology Unit Hospital San Raffaele, Institute of Experimental Neurology-INSPE, Italy; Vita-Salute University San Raffaele, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.03.013DOI Listing
March 2018

Disease-modifying treatments modulate myeloid cells in multiple sclerosis patients.

Neurol Sci 2018 Feb 28;39(2):373-376. Epub 2017 Nov 28.

Division of Neuroscience, Institute of Experimental Neurology, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1007/s10072-017-3176-2DOI Listing
February 2018

Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study.

Lancet Neurol 2018 02 21;17(2):133-142. Epub 2017 Dec 21.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/S1474-4422(17)30469-6DOI Listing
February 2018

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.

Mult Scler 2018 02 20;24(2):96-120. Epub 2018 Jan 20.

Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunology (FZI), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1177/1352458517751049DOI Listing
February 2018

Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis.

Cell Death Dis 2018 02 14;9(2):250. Epub 2018 Feb 14.

Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, 20132, Milan, Italy.

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http://www.nature.com/articles/s41419-018-0288-4
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http://dx.doi.org/10.1038/s41419-018-0288-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833860PMC
February 2018

Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury.

J Neuroinflammation 2018 Feb 23;15(1):58. Epub 2018 Feb 23.

Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.

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http://dx.doi.org/10.1186/s12974-018-1085-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824446PMC
February 2018

Necrotic-hemorrhagic myelitis: A rare malignant variant of parainfectious acute disseminated encephalomyelitis in childhood.

J Neurol Sci 2018 01 23;384:58-60. Epub 2017 Nov 23.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.11.032DOI Listing
January 2018

Structural connectivity-defined thalamic subregions have different functional connectivity abnormalities in multiple sclerosis patients: Implications for clinical correlations.

Hum Brain Mapp 2017 12 7;38(12):6005-6018. Epub 2017 Sep 7.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://doi.wiley.com/10.1002/hbm.23805
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http://dx.doi.org/10.1002/hbm.23805DOI Listing
December 2017

Weight gain after subthalamic nucleus deep brain stimulation in Parkinson's disease is influenced by dyskinesias' reduction and electrodes' position.

Neurol Sci 2017 Dec 14;38(12):2123-2129. Epub 2017 Sep 14.

Department of Neurology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20123, Milan, MI, Italy.

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http://dx.doi.org/10.1007/s10072-017-3102-7DOI Listing
December 2017

No evidence of disease activity is associated with reduced rate of axonal retinal atrophy in MS.

Neurology 2017 Dec 15;89(24):2469-2475. Epub 2017 Nov 15.

From the Neurological Department and Institute of Experimental Neurology (INSPE) (M.P., S.G., G.D.M., S.M., L.M., V.M., G.C., L.L.), Scientific Institute, Hospital San Raffaele; and University Vita-Salute San Raffaele (M.P., S.G., G.C., L.L.), Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004736DOI Listing
December 2017

Smart watch, smarter EDSS: Improving disability assessment in multiple sclerosis clinical practice.

J Neurol Sci 2017 Dec 27;383:166-168. Epub 2017 Oct 27.

Department of Neurology, San Raffaele Hospital, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.10.043DOI Listing
December 2017

Long-term disability progression in primary progressive multiple sclerosis: a 15-year study.

Brain 2017 Nov;140(11):2814-2819

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1093/brain/awx250DOI Listing
November 2017

Brain network connectivity differs in early-onset neurodegenerative dementia.

Neurology 2017 Oct 27;89(17):1764-1772. Epub 2017 Sep 27.

From the Neuroimaging Research Unit (M. Filippi, S.B., E.C., F.I., A.M., F.C., F.A.), Department of Neurology (M. Filippi, G.M., M. Falautano, G.C.), Institute of Experimental Neurology, Division of Neuroscience, and Department of Neuroradiology and CERMAC (A.F.), Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664301PMC
October 2017

Fluid biomarker and electrophysiological outcome measures for progressive MS trials.

Mult Scler 2017 Oct;23(12):1600-1613

Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital of Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1177/1352458517732844DOI Listing
October 2017

Structural and functional brain signatures of C9orf72 in motor neuron disease.

Neurobiol Aging 2017 09 6;57:206-219. Epub 2017 Jun 6.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.05.024DOI Listing
September 2017

MRI substrates of sustained attention system and cognitive impairment in pediatric MS patients.

Neurology 2017 Sep 18;89(12):1265-1273. Epub 2017 Aug 18.

From the Neuroimaging Research Unit (E.D.M., E.P., M.F., M.A.R.) and Department of Neurology (E.D.M., L.M., A. Fiorino, G.C., M.F., M.A.R.), Institute of Experimental Neurology, Division of Neuroscience, and Department of Neuroradiology (A. Falini), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Multiple Sclerosis Center (A.G., L.P.), Ospedale di Gallarate; Department of Child Neurology and Psychiatry (P.V., M.C.P.), C. Mondino National Neurological Institute, Brain and Behaviour Department, University of Pavia; Multiple Sclerosis Center (R.C.), Spedali Civili of Brescia; and Department NEUROFARBA (M.P.A.), Section Neurosciences, University of Florence, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004388DOI Listing
September 2017

The Role of T1-Weighted Derived Measures of Neurodegeneration for Assessing Disability Progression in Multiple Sclerosis.

Front Neurol 2017 4;8:433. Epub 2017 Sep 4.

Neuroimaging Research Unit, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.3389/fneur.2017.00433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591328PMC
September 2017