Giampaolo Merlini

Giampaolo Merlini

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Giampaolo Merlini

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Light Chains With Heavy Effects.

Am J Kidney Dis 2019 Oct 16. Epub 2019 Oct 16.

Amyloidosis Research and Treatment Centre, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2019.08.009DOI Listing
October 2019

Predicting survival in light chain amyloidosis.

Haematologica 2019 Jul;104(7):1294-1296

Amyloidosis Research and Treatment Center, Foundation "Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo", and Department of Molecular Medicine, University of Pavia, Italy.

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http://dx.doi.org/10.3324/haematol.2019.218859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601088PMC
July 2019

High sensitivity M-protein detection in a case of light-chain cardiac amyloidosis without evidence of plasma cell dyscrasia.

Am J Hematol 2019 May 8;94(5):619-621. Epub 2019 Jan 8.

Division of Clinical Biochemistry & Immunology, Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25383DOI Listing
May 2019

Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration.

Am J Physiol Heart Circ Physiol 2019 May 15;316(5):H1158-H1166. Epub 2019 Mar 15.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.

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http://dx.doi.org/10.1152/ajpheart.00788.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580397PMC
May 2019

Treatment of cardiac transthyretin amyloidosis: an update.

Eur Heart J 2019 May 20. Epub 2019 May 20.

Amyloidosis Research and Treatment Centre, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100, Pavia, Italy.

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https://academic.oup.com/eurheartj/advance-article/doi/10.10
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http://dx.doi.org/10.1093/eurheartj/ehz298DOI Listing
May 2019

Differential serum levels of interleukin-37 in patients with tumour necrosis factor receptor-associated periodic syndrome (TRAPS).

Clin Exp Rheumatol 2019 May 30. Epub 2019 May 30.

Research Centre of Systemic Autoinflammatory Diseases, Behçet's Disease Clinic and Rheumatology-Ophthalmology Collaborative Uveitis Centre, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy.

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May 2019

New Insights Into a Multifaceted Disease.

Mayo Clin Proc 2019 03;94(3):388-390

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2019.01.029DOI Listing
March 2019

Improved outcomes for kidney transplantation in AL amyloidosis: impact on practice.

Kidney Int 2019 02;95(2):258-260

Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.11.003DOI Listing
February 2019

ATR-FTIR Spectroscopy Supported by Multivariate Analysis for the Characterization of Adipose Tissue Aspirates from Patients Affected by Systemic Amyloidosis.

Anal Chem 2019 Feb 4;91(4):2894-2900. Epub 2019 Feb 4.

Department of Biotechnology and Biosciences , University of Milano-Bicocca , Piazza della Scienza 2 , 20126 Milano , Italy.

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http://dx.doi.org/10.1021/acs.analchem.8b05008DOI Listing
February 2019

When should treatment of AL amyloidosis start at relapse? Early, to prevent organ progression.

Blood Adv 2019 01;3(2):212-215

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/bloodadvances.2018021253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341187PMC
January 2019

Management of the elderly patient with AL amyloidosis.

Eur J Intern Med 2018 12 23;58:48-56. Epub 2018 May 23.

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Department of Molecular Medicine, University of Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2018.05.004DOI Listing
December 2018

Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee.

Amyloid 2018 Dec 7;25(4):215-219. Epub 2019 Jan 7.

h Department of Immunology, Genetics and Pathology , Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.1080/13506129.2018.1549825DOI Listing
December 2018

Treatment of AL amyloidosis with bendamustine: a study of 122 patients.

Blood 2018 11 14;132(18):1988-1991. Epub 2018 Aug 14.

Department of Internal Medicine V, Hematology/Oncology/Rheumatology, Amyloidosis Center, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood-2018-04-845396DOI Listing
November 2018

Therapies for cardiac light chain amyloidosis: An update.

Int J Cardiol 2018 Nov;271:152-160

Amyloidosis Research and Treatment Centre, IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2018.05.018DOI Listing
November 2018

Seek and You Shall Find: Is Subclinical Amyloid More Common Than Expected?

Mayo Clin Proc 2018 11;93(11):1546-1548

Amyloidosis Research and Treatment Centre, Fondazione IRCCS Policlinico San Matteo, Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2018.09.008DOI Listing
November 2018

Monoclonal gammopathy of clinical significance: a novel concept with therapeutic implications.

Blood 2018 10 16;132(14):1478-1485. Epub 2018 Jul 16.

Amyloidosis Research and Treatment Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; and.

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http://dx.doi.org/10.1182/blood-2018-04-839480DOI Listing
October 2018

Systemic immunoglobulin light chain amyloidosis.

Nat Rev Dis Primers 2018 10 25;4(1):38. Epub 2018 Oct 25.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://www.nature.com/articles/s41572-018-0034-3
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http://dx.doi.org/10.1038/s41572-018-0034-3DOI Listing
October 2018

Outrageous prices of orphan drugs: a call for collaboration.

Lancet 2018 09 20;392(10149):791-794. Epub 2018 Jul 20.

IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy; Unit of Nephrology and Dialysis, Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy; Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183106
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http://dx.doi.org/10.1016/S0140-6736(18)31069-9DOI Listing
September 2018

Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.

N Engl J Med 2018 Sep 27;379(11):1007-1016. Epub 2018 Aug 27.

From the Columbia University Vagelos College of Physicians and Surgeons (M.S.M.) and Pfizer (J.H.S., A.I.B., P.H., J.S., M.B.S.), New York; Syneos Health, Raleigh, NC (B.G.); University College London and St. Bartholomew's Hospital, London (P.M.E.); the Amyloidosis Center, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, and the University of Pavia, Pavia (G.M.), and the Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna (C.R.) - both in Italy; the Amyloidosis Center (CEPARM), Federal University of Rio de Janeiro, Rio de Janeiro (M.W-C.); the Amyloidosis Center, Medical University of Heidelberg, Heidelberg, Germany (A.V.K.); the Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (M.G.); Stanford University School of Medicine, Stanford, CA (R.W.); the French Referral Center for Cardiac Amyloidosis, Amyloidosis Mondor Network, GRC Amyloid Research Institute and Department of Cardiology, Assistance Publique-Hôpitaux de Paris, CHU Henri Mondor, and INSERM Unité 955, Clinical Investigation Center 006, and DHU ATVB, Creteil, France (T.D.); Penn Presbyterian Medical Center, University of Pennsylvania Health System, Philadelphia (B.M.D.); the Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago (S.J.S.); Cleveland Clinic, Cleveland (M.H.); the Medical University of South Carolina, Charleston (D.P.J.); and Pfizer, Groton, CT (T.A.P., S.R., M.S.).

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http://www.nejm.org/doi/10.1056/NEJMoa1805689
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http://dx.doi.org/10.1056/NEJMoa1805689DOI Listing
September 2018

Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis.

N Engl J Med 2018 Jul;379(1):22-31

From the Indiana University School of Medicine, Indianapolis (M.D.B.); Centro de Estudos em Paramiloidose Antônio Rodrigues de Mello, National Amyloidosis Referral Center, University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro (M.W.-C.); Amyloidosis Center, Boston University School of Medicine (J.L.B.) and Brigham and Women's Hospital, Harvard Medical School (A.M.S., S.D.S.), Boston; Johns Hopkins University, Baltimore (M.P.); Mayo Clinic, Rochester, MN (P.J.D., W.J.L., M.A.G.); University of California, Irvine, Irvine (A.K.W.); Amyloid Network-Hospital Henri Mondor-Assistance Publique-Hôpitaux de Paris (AP-HP)-Université Paris Est, Créteil, France (V.P.-B.); Institute for Neurologic Research Raúl Carrea, FLENI, Buenos Aires (F.A.B.); Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia (G.M., L.O.), and Unit of Neurology, University Hospital, Messina (G.V.) - both in Italy; Hospital AACD (Associação de Assistência à Criança Deficiente), São Paulo (M.S.); Columbia University Medical Center (T.H.B.) and Mount Sinai Medical Center (P.D.G.), New York; University College London-National Amyloidosis Centre, London (C.W.); Penn Presbyterian Medical Center, University of Pennsylvania Health System, Philadelphia (B.M.D.); Centre Hospitaliere Universitaire Bicêtre, AP-HP, Unité 1195, INSERM, Université Paris-Sud, Paris (D.A.); Oregon Health and Science University, Portland (S.B.H.); Centro Hospitalar Lisboa Norte-Hospital de Santa Maria, Lisbon (I.C.), and Centro Hospitalar do Porto, Porto (T.C.) - both in Portugal; Universitätsklinikum Münster, Münster, Germany (H.H.S.); Hospital Clínic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (J.M.C.), and Hospital Universitari Vall d'Hebron (J.G.), Barcelona; Auckland City Hospital, Auckland, New Zealand (E.G.); and Ionis Pharmaceuticals, Carlsbad, CA (B.P.M., S.G.H., T.J.K., B.W.M., S.W.J., B.F.B., E.J.A.).

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http://dx.doi.org/10.1056/NEJMoa1716793DOI Listing
July 2018

Novel Therapies in Light Chain Amyloidosis.

Kidney Int Rep 2018 May 28;3(3):530-541. Epub 2017 Nov 28.

Amyloidosis Research and Treatment Center, Foundation "Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo," and Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1016/j.ekir.2017.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976806PMC
May 2018

Proteomics with Mass Spectrometry Imaging: Beyond Amyloid Typing.

Proteomics 2018 04 8;18(7):e1700353. Epub 2018 Mar 8.

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1002/pmic.201700353DOI Listing
April 2018

The elusive pathogenesis of Schnitzler syndrome.

Blood 2018 03;131(9):944-946

Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo; University of Pavia.

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http://dx.doi.org/10.1182/blood-2018-01-824862DOI Listing
March 2018

Light Chain Amyloidosis.

Mediterr J Hematol Infect Dis 2018 1;10(1):e2018022. Epub 2018 Mar 1.

Amyloidosis Research and Treatment Center, Foundation "Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo" and Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.4084/MJHID.2018.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841939PMC
March 2018

Presentation and outcome with second-line treatment in AL amyloidosis previously sensitive to nontransplant therapies.

Blood 2018 02 3;131(5):525-532. Epub 2017 Nov 3.

Amyloidosis Research and Treatment Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, and.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2017-04
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http://dx.doi.org/10.1182/blood-2017-04-780544DOI Listing
February 2018

New concepts in the treatment and diagnosis of amyloidosis.

Expert Rev Hematol 2018 02 10;11(2):117-127. Epub 2018 Jan 10.

a Amyloidosis Research and Treatment Center, Foundation 'Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo', and Department of Molecular Medicine , University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/17474086.2018.1424534DOI Listing
February 2018

Attitudes about when and how to treat patients with AL amyloidosis: an international survey.

Amyloid 2017 Dec 31;24(4):213-216. Epub 2017 Aug 31.

a Division of Hematology , Mayo Clinic , Rochester , MN , USA.

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http://dx.doi.org/10.1080/13506129.2017.1370421DOI Listing
December 2017

Lenalidomide and dexamethasone in patients with POEMS syndrome: results of a prospective, open-label trial.

Br J Haematol 2017 12 19;179(5):748-755. Epub 2017 Oct 19.

Neuromuscular and Neuroimmunology Service, Department of Medical Biotechnology and Translational Medicine, Milan University, Humanitas Clinical and Research Hospital IRCCS, Milan, Italy.

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http://dx.doi.org/10.1111/bjh.14966DOI Listing
December 2017

Emerging therapeutic targets currently under investigation for the treatment of systemic amyloidosis.

Expert Opin Ther Targets 2017 12;21(12):1095-1110

a Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Department of Molecular Medicine , University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/14728222.2017.1398235DOI Listing
December 2017

AL amyloidosis: from molecular mechanisms to targeted therapies.

Hematology Am Soc Hematol Educ Program 2017 12;2017(1):1-12

Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/asheducation-2017.1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142527PMC
December 2017

Cardiac Light Chain Amyloidosis: The Role of Metal Ions in Oxidative Stress and Mitochondrial Damage.

Antioxid Redox Signal 2017 Sep 3;27(9):567-582. Epub 2017 Mar 3.

1 Department of Molecular Biochemistry and Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri ," Milan, Italy .

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http://dx.doi.org/10.1089/ars.2016.6848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567464PMC
September 2017

The lung in amyloidosis.

Eur Respir Rev 2017 Sep 6;26(145). Epub 2017 Sep 6.

Amyloidosis Research and Treatment Centre, Foundation IRCCS Policlinico San Matteo and Dept of Molecular Medicine, University of Pavia, Pavia, Italy

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http://dx.doi.org/10.1183/16000617.0046-2017DOI Listing
September 2017

The utility of MASS-FIX to detect and monitor monoclonal proteins in the clinic.

Am J Hematol 2017 Aug 1;92(8):772-779. Epub 2017 Jun 1.

Division of Hematology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24772DOI Listing
August 2017

Patients with light-chain amyloidosis and low free light-chain burden have distinct clinical features and outcome.

Blood 2017 08 25;130(5):625-631. Epub 2017 May 25.

Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; and.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2017-02
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http://dx.doi.org/10.1182/blood-2017-02-767467DOI Listing
August 2017

How do we improve treatments for patients with amyloidosis using proteomics?

Expert Rev Proteomics 2017 07 23;14(7):561-563. Epub 2017 May 23.

a Amyloidosis Research and Treatment Center , Fondazione IRCCS Policlinico San Matteo and University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/14789450.2017.1331737DOI Listing
July 2017

Immunoglobulin Light Chain Systemic Amyloidosis.

Cancer Treat Res 2016;169:273-318

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://link.springer.com/10.1007/978-3-319-40320-5_15
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http://dx.doi.org/10.1007/978-3-319-40320-5_15DOI Listing
June 2017

Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system.

J Neuroinflammation 2017 06 6;14(1):115. Epub 2017 Jun 6.

i3S - Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.

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http://dx.doi.org/10.1186/s12974-017-0891-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460450PMC
June 2017

Design and Rationale of the Phase 3 ATTR-ACT Clinical Trial (Tafamidis in Transthyretin Cardiomyopathy Clinical Trial).

Circ Heart Fail 2017 Jun;10(6)

From the Center for Advanced Cardiac Care, Columbia University College of Physicians and Surgeons, NY (M.S.M); Cardiovascular Medicine, University College London, United Kingdom (P.E.); IRCCS Policlinico San Matteo, University of Pavia, Italy (G.M.); Division of Cardiology, Northwestern University, Chicago, IL (S.J.S.); National Amyloidosis Referral Center, Centro de Estudos em Paramiloidose Antônio Rodrigues de Mello, Federal University of Rio de Janeiro, Brazil (M.W.C.); Pfizer, Inc, Collegeville, PA (A.F., C.H.); inVentiv Health, Burlington, MA (B.G.); Pfizer, Inc, Groton, CT (S.R., J.S.); Pfizer, Inc, NY (M.B.S.); and Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy (C.R.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003815DOI Listing
June 2017

Systemic amyloidosis: novel therapies and role of biomarkers.

Nephrol Dial Transplant 2017 May;32(5):770-780

Amyloidosis Research and Treatment Center, Foundation Scientific Institute Policlinico San Matteo, Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://ndt.oxfordjournals.org/content/early/2016/08/18/ndt.g
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http://dx.doi.org/10.1093/ndt/gfw305DOI Listing
May 2017

Diagnostic challenges in hereditary transthyretin amyloidosis with polyneuropathy: avoiding misdiagnosis of a treatable hereditary neuropathy.

J Neurol Neurosurg Psychiatry 2017 05 10;88(5):457-458. Epub 2017 Feb 10.

Amyloidosis Research and Treatment Center, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1136/jnnp-2016-315262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529976PMC
May 2017

A phase 2 trial of pomalidomide and dexamethasone rescue treatment in patients with AL amyloidosis.

Blood 2017 04 27;129(15):2120-2123. Epub 2017 Jan 27.

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2016-12-756528DOI Listing
April 2017

Serum-free light-chain analysis in diagnosis and management of multiple myeloma and related conditions.

Scand J Clin Lab Invest Suppl 2016 28;245:S113-8. Epub 2016 Jul 28.

a Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine , University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/00365513.2016.1210337DOI Listing
March 2017

Prognostication of survival and progression to dialysis in AA amyloidosis.

Amyloid 2017 Mar;24(sup1):136-137

a Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo , Pavia , Italy.

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http://dx.doi.org/10.1080/13506129.2017.1289917DOI Listing
March 2017

Identification and quantification of urinary monoclonal proteins by capillary electrophoresis in AL amyloidosis.

Amyloid 2017 03;24(sup1):66-67

a Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS) Policlinico San Matteo, Department of Molecular Medicine, University of Pavia , Pavia , Italy and.

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http://dx.doi.org/10.1080/13506129.2017.1293643DOI Listing
March 2017

Urinary albumin to creatinine ratio in diagnosis and risk stratification of renal AL amyloidosis.

Amyloid 2017 03;24(sup1):68-69

a Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Policlinico San Matteo , Pavia , Italy and.

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http://dx.doi.org/10.1080/13506129.2017.1293644DOI Listing
March 2017

Patterns of relapse after upfront bortezomib therapy in AL amyloidosis.

Amyloid 2017 03;24(sup1):60-61

a Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia , Pavia , Italy.

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https://www.tandfonline.com/doi/full/10.1080/13506129.2017.1
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http://dx.doi.org/10.1080/13506129.2017.1292901DOI Listing
March 2017

Patients with AL amyloidosis and low free light-chain burden have distinct clinical features and outcome.

Amyloid 2017 03;24(sup1):64-65

a Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia , Pavia , Italy.

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https://www.tandfonline.com/doi/full/10.1080/13506129.2017.1
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http://dx.doi.org/10.1080/13506129.2017.1293517DOI Listing
March 2017

Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines.

Amyloid 2016 Dec 24;23(4):209-213. Epub 2016 Nov 24.

g Department of Immunology , Genetics and Pathology, Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.1080/13506129.2016.1257986DOI Listing
December 2016

Advances in proteomic study of cardiac amyloidosis: progress and potential.

Expert Rev Proteomics 2016 Nov 19;13(11):1017-1027. Epub 2016 Oct 19.

a Amyloidosis Research and Treatment Center , Fondazione IRCCS Policlinico San Matteo, and University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/14789450.2016.1242417DOI Listing
November 2016

Expanding the spectrum of systemic amyloid diseases: a new hint from the kidney.

Kidney Int 2016 09;90(3):479-81

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.05.029DOI Listing
September 2016

What is new in diagnosis and management of light chain amyloidosis?

Blood 2016 07 6;128(2):159-68. Epub 2016 Apr 6.

Amyloidosis Research and Treatment Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2016-01-629790DOI Listing
July 2016

Clinical Pregenetic Screening for Stroke Monogenic Diseases: Results From Lombardia GENS Registry.

Stroke 2016 07 31;47(7):1702-9. Epub 2016 May 31.

From the Department of Cerebrovascular Disease, IRCCS Foundation Carlo Besta Neurological Institute, Milan, Italy (A.B., G.B.B., E.A.P., N.T.); Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (H.S.M.); Department of Bio-Medical Informatics, University of Pavia, Pavia, Italy (S.Q.); Department of Inherited Cardiovascular Disease, Foundation IRCCS Policlinico San Matteo, Pavia, Italy (E.A., M.G.); Neurology Unit, Department of Neuroscience and Sensory Organs, Maggiore Policlinico Hospital Foundation IRCCS Ca' Granda, Milan, Italy (S.L., L.C.); Neurology and Stroke Unit, Department of Urgency (G.M., A.C.), Department of Genetics (C.C., G.G.), and Brain MRI 3T Research Center (P.V.), IRCCS Foundation Casimiro Mondino Neurological Institute, Pavia, Italy; Department of Genetics of Neurodegenerative and Metabolic Diseases, IRCCS Foundation C, Besta Neurological Institute, Milan, Italy (F.T., C.G., S.B.); Department of Medical Genetics, Niguarda Ca' Granda Hospital, Milan, Italy (S.P., L.M.); Department of Genomics for Human Disease Diagnosis and Laboratory of Clinical Molecular Biology, IRCCS San Raffaele hospital, Milan, Italy (P.C., M.F.); University Vita-Salute, Milano, Italy (M.F.); Dino Ferrari Centre, Neuroscience Section, Department of Pathophysiology and Transplantation (DEPT), University of Milan, Milan, Italy (S.C., D.R., G.P.C.); Neurology Unit, Department of Neuroscience and Sensory Organs, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico Milan, Milan, Italy (S.C., D.R., G.P.C.); Department of Molecular Biology, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Lecco, Italy (M.T.B.); Center for amyloidosis, Department of medical Thecnologies, IRCCS Foundation San Matteo Policlinico, Pavia, Italy (L.O., G.M.); Vascular Neurology - Spedali Civili, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy (A. Pezzini, A. Padovani); Stroke Unit, Departmen

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http://dx.doi.org/10.1161/STROKEAHA.115.012281DOI Listing
July 2016

In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study.

Sci Rep 2016 07 4;6:29096. Epub 2016 Jul 4.

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy.

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http://dx.doi.org/10.1038/srep29096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931462PMC
July 2016

European Collaborative Study Defining Clinical Profile Outcomes and Novel Prognostic Criteria in Monoclonal Immunoglobulin M-Related Light Chain Amyloidosis.

J Clin Oncol 2016 06 25;34(17):2037-45. Epub 2016 Apr 25.

Sajitha Sachchithanantham, Murielle Roussel, Shameem Mahmood, Julian Gillmore, Helen Lachmann, Philip N. Hawkins, and Ashutosh D. Wechalekar, University College London Medical School, London, United Kingdom; Murielle Roussel, Centre Hospitalier Universitaire (CHU) Purpan, Toulouse; Arnaud Jaccard, CHU Limoges, Limoges, France; Giovanni Palladini and Giampaolo Merlini, University of Pavia; Catherine Klersy, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; Christopher Paul Venner, University of Alberta, Edmonton, Alberta, Canada; and Simon Gibbs, Westmead Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.2015.63.3123DOI Listing
June 2016

Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.

Circulation 2016 Jun 22;133(24):2404-12. Epub 2016 Apr 22.

From National Amyloidosis Centre, Division of Medicine (J.D.G., A.D.W., C.C.Q., H.J.L., T.R., M.F., K.F., T.L., F.W.V., C.J.W., D.F.H., P.N.H.) and Barts Heart Centre, Institute of Cardiovascular Science (J.C.M.), University College London, UK; Clinical Cardiovascular Research Laboratory for the Elderly, Columbia University Medical Center, New York (M.S.M., S.B., A.C.); Department of Cardiology and Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (R.H.F., S.D.); Amyloidosis Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Italy (G.M., G.P., P.M.); Department of Cardiology, University Hospital Henri Mondor, Amyloidosis Mondor Network, Creteil, France (T.D.); Division of Hematology, Division of Cardiovascular Diseases, and Department of Radiology, Division of Nuclear Medicine, Department of Medicine, Mayo Clinic, Rochester, MN (A.D., M.G., G.B.J.); Amyloidosis Center, Boston University School of Medicine and Boston Medical Center, MA (J.L.B., F.L.R.); Departments of Nuclear Medicine and Molecular Imaging (A.W.J.M.G.) and Rheumatology and Clinical Immunology (B.P.H.), University of Groningen, University Medical Center Groningen, The Netherlands; Department of Nuclear Medicine, S. Orsola-Malpighi Hospital, and Cardiology Unit, Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater-University of Bologna, Italy (P.L.G., C.R.); and Yale University School of Medicine, Section of Cardiovascular Medicine, New Haven, CT (E.J.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.021612DOI Listing
June 2016

Monoclonal IgM-related AL amyloidosis.

Best Pract Res Clin Haematol 2016 06 23;29(2):241-248. Epub 2016 Aug 23.

Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216926163001
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http://dx.doi.org/10.1016/j.beha.2016.08.013DOI Listing
June 2016