Dr Giacomo Cavalli, PhD - Institute of Human Genetics - PhD

Dr Giacomo Cavalli

PhD

Institute of Human Genetics

PhD

Montpellier | France

Main Specialties: Biology

Additional Specialties: Epigenetics, chromosome biology

Dr Giacomo Cavalli, PhD - Institute of Human Genetics - PhD

Dr Giacomo Cavalli

PhD
Introduction

Giacomo Cavalli dis his PhD at the ETH in Zürich, working in chromatin and transcription in yeast. He then moved to the University of Heidelberg, where he discovered transgenerational inheritance of chromatin states in metazoans in 1998 by working on Polycomb and Trithorax group proteins in Drosophila with Renato Paro.

He then started his lab in 1999 at the Institute of Human Genetics in Montpellier. The Cavalli lab has shown that the 3D structure of chromosomes can be epigenetically heritable and that it contributes to genome regulation. Furthermore, they provided the first high-resolution description of the principles of genome folding in metazoans. Finally, the Cavalli lab showed that PcG proteins regulate cell proliferation and have tumour suppression activity in flies.

Giacomo Cavalli has received numerous distinctions and awards, including a nomination to EMBO member in 2008, the CNRS silver medal in 2011, the Allianz Foundation Award in 2012 and two advanced grants of the European Research Council (ERC).

Primary Affiliation: Institute of Human Genetics - Montpellier , France

Specialties:

Additional Specialties:

Research Interests:


View Dr Giacomo Cavalli’s Resume / CV
Metrics

92

Publications

402

Profile Views

313

Reads

3814

PubMed Central Citations

Education
Dec 1994
PhD
Natural Sciences
Top co-authors
Bernd Schuettengruber
Bernd Schuettengruber

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15
Tom Sexton
Tom Sexton

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10
Sergey Lavrov
Sergey Lavrov

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6
Jerome Dejardin
Jerome Dejardin

Inserm Avenir: 'Biology of repetitive sequences'-Institute of Human Genetics

6
Thierry Cheutin
Thierry Cheutin

Institut de Génétique Humaine

5
Amos Tanay
Amos Tanay

Weizmann Institute of Science

5
Benjamin Leblanc
Benjamin Leblanc

University of Copenhagen

5
Boyan Bonev
Boyan Bonev

Institute of Human Genetics

5

Publications

92Publications

313Reads

3814PubMed Central Citations

Technical Review: A Hitchhiker's Guide to Chromosome Conformation Capture.

Methods Mol Biol 2018 ;1675:233-246

Institute of Human Genetics, Centre National de la Recherche UMR9002, Montpellier, France.

View Article
June 2018
1 Read

TADs are 3D structural units of higher-order chromosome organization in .

Sci Adv 2018 Feb 28;4(2):eaar8082. Epub 2018 Feb 28.

Institute of Human Genetics, CNRS, Univ Montpellier, Montpellier, France.

View Article
February 2018
5 Reads
2 PubMed Central Citations(source)

Following the Motion of Polycomb Bodies in Living Drosophila Embryos.

Methods Mol Biol 2016 ;1480:283-8

Institut de Génétique Humaine, CNRS UPR 1142, 141, rue de la Cardonille, 34396, Montpellier Cedex 5, France.

View Article
January 2018
5 Reads

Chromosome Conformation Capture on Chip (4C): Data Processing.

Methods Mol Biol 2016 ;1480:243-61

Institut de Génétique Humaine, CNRS UPR 1142, 141, rue de la Cardonille, 34396, Montpellier, France.

View Article
January 2018
2 Reads

Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.

Nat Commun 2017 Nov 24;8(1):1753. Epub 2017 Nov 24.

Centre de Biochimie Structurale, CNRS UMR5048, INSERM U1054, Université de Montpellier, 29 rue de Navacelles, 34090, Montpellier, France.

View Article
November 2017
3 Reads
3 PubMed Central Citations(source)
10.74 Impact Factor

Multiscale 3D Genome Rewiring during Mouse Neural Development.

Cell 2017 Oct;171(3):557-572.e24

Institute of Human Genetics, UMR 9002 of the CNRS and the Université de Montpellier, 34396 Montpellier, France. Electronic address:

View Article
October 2017
4 Reads
17 PubMed Central Citations(source)
32.24 Impact Factor

Genome Regulation by Polycomb and Trithorax: 70 Years and Counting.

Cell 2017 Sep;171(1):34-57

Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, 141 Rue de la Cardonille, 34396 Montpellier Cedex 5, France. Electronic address:

View Article
September 2017
20 Reads
19 PubMed Central Citations(source)
32.24 Impact Factor

Chromosome topology guides the Dosage Compensation Complex for target gene activation.

EMBO Rep 2017 Aug 9. Epub 2017 Aug 9.

Molecular Biology Division, Biomedical Center and Center for Integrated Protein Science Ludwig-Maximilians-University, Munich, Germany

View Article
August 2017
2 Reads
1 PubMed Central Citation(source)
9.05 Impact Factor

MACVIA-LR (Fighting Chronic Diseases for Active and Healthy Ageing in Languedoc-Roussillon): A Success Story of the European Innovation Partnership on Active and Healthy Ageing.

Authors:
J Bousquet R Bourret T Camuzat P Augé J Bringer M Noguès O Jonquet J E de la Coussaye J Ankri M Cesari O Guérin B Vellas H Blain S Arnavielhe A Avignon B Combe G Canovas C Daien G Dray A Dupeyron C Jeandel I Laffont D Laune C Marion E Pastor J Y Pélissier B Galan J Reynes J C Reuzeau A Bedbrook S Granier P A Adnet M Amouyal B Alomène P L Bernard C Berr D Caimmi P G Claret D J Costa J P Cristol P Fesler D Hève J Millot-Keurinck D Morquin G Ninot M C Picot N Raffort F Roubille A Sultan J Touchon V Attalin C Azevedo M Badin K Bakhti B Bardy M P Battesti X Bobia C Boegner S Boichot H Y Bonnin S Bouly C Boubakri J L Bourrain G Bourrel V Bouix V Bruguière S Cade W Camu V Carre G Cavalli G Cayla R Chiron P Coignard F Coroian P Costa J Cottalorda B Coulet A L Coupet M C Courrouy-Michel P Courtet V Cros F Cuisinier M Danko P Dauenhauer M Dauzat M David J M Davy D Delignières P Demoly J Desplan P Dujols G Dupeyron O Engberink M Enjalbert C Fattal J Fernandes M Fouletier P Fraisse P Gabrion M Gellerat-Rogier A Gelis C Genis N Giraudeau A Y Goucham F Gouzi F Gressard J C Gris B Guillot D Guiraud V Handweiler M Hayot C Hérisson C Heroum D Hoa S Jacquemin S Jaber D Jakovenko C Jorgensen P Kouyoudjian R Lamoureux L Landreau M Lapierre D Larrey C Laurent M S Léglise J M Lemaitre A Le Quellec F Leclercq S Lehmann B Lognos Cj M Lussert A Makinson K Mandrick P Mares P Martin-Gousset A Matheron G Mathieu M Meissonnier G Mercier P Messner C Meunier M Mondain R Morales J Morel D Mottet P Nérin P Nicolas F Nouvel D Paccard G Pandraud M P Pasdelou J L Pasquié K Patte S Perrey Y M Pers F Portejoie J L E Pujol X Quantin I Quéré S Ramdani J Ribstein I Rédini-Martinez S Richard K Ritchie J P Riso F Rivier J M Robine C Rolland E Royère D Sablot J L Savy L Schifano P Senesse R Sicard Y Stephan D Strubel G Tallon M Tanfin H Tassery I Tavares K Torre V Tribout A Uziel P Van de Perre F Venail C Vergne-Richard G Vergotte L Vian F Vialla F Viart M Villain E Viollet M Ychou J Mercier

J Frailty Aging 2016 ;5(4):233-241

Professor Jean Bousquet, CHRU, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France, Tel +33 611 42 88 47,

View Article
June 2017
5 Reads
1 PubMed Central Citation(source)

Chromosome conformation capture technologies and their impact in understanding genome function.

Chromosoma 2017 02 30;126(1):33-44. Epub 2016 Apr 30.

Institute of Human Genetics, UPR1142 CNRS, 141 Rue de la Cardonille, 34396, Montpellier Cedex 5, France.

View Article
February 2017
3 Reads
12 PubMed Central Citations(source)
4.60 Impact Factor

Three-Dimensional Genome Organization and Function in Drosophila.

Genetics 2017 01;205(1):5-24

Human Genetics, Centre National de la Recherche Scientifique, UPR1142 and University of Montpellier, 34396 Montpellier Cedex 5, France

View Article
January 2017
2 Reads
4 PubMed Central Citations(source)

Coordinate redeployment of PRC1 proteins suppresses tumor formation during Drosophila development.

Nat Genet 2016 11 19;48(11):1436-1442. Epub 2016 Sep 19.

Institute of Human Genetics, UPR1142 CNRS, 141 Rue de la Cardonille, 34396, Montpellier Cedex 5, France.

View Article
November 2016
2 Reads
10 PubMed Central Citations(source)
29.35 Impact Factor

Organization and function of the 3D genome.

Nat Rev Genet 2016 10;17(11):661-678

Institute of Human Genetics, UPR1142 National Centre for Scientific Research (CNRS); and University of Montpellier, 141 Rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
October 2016
2 Reads
52 PubMed Central Citations(source)
36.98 Impact Factor

Regulation of Genome Architecture and Function by Polycomb Proteins.

Trends Cell Biol 2016 07 16;26(7):511-525. Epub 2016 May 16.

Institute of Human Genetics, CNRS UPR1142 and University of Montpellier, 141 Rue de la Cardonille, 34396, Montpellier Cedex 5, France. Electronic address:

View Article
July 2016
3 Reads
14 PubMed Central Citations(source)
12.01 Impact Factor

EZH2 in normal hematopoiesis and hematological malignancies.

Oncotarget 2016 Jan;7(3):2284-96

Department of Biological Hematology, CHU Montpellier, Montpellier, France.

View Article
January 2016
2 Reads
11 PubMed Central Citations(source)
6.36 Impact Factor

PRC1 proteins orchestrate three-dimensional genome architecture.

Authors:
Giacomo Cavalli

Nat Genet 2015 Oct;47(10):1105-6

Institute of Human Genetics, UPR 1142, CNRS, Montpellier, France.

View Article
October 2015
2 Reads
29.35 Impact Factor

Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis.

Biol Open 2015 Aug 14;4(9):1109-21. Epub 2015 Aug 14.

Institute of Human Genetics (IGH), UPR 1142, CNRS, Montpellier 34396, France

View Article
August 2015
2 Reads

Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains.

BMC Genomics 2015 Aug 15;16:607. Epub 2015 Aug 15.

Institut de Génétique Moléculaire de Montpellier, UMR5535, CNRS, Université de Montpellier, 1919 Route de Mende, 34293, Montpellier, Cedex 5, France.

View Article
August 2015
6 Reads
2 PubMed Central Citations(source)
3.99 Impact Factor

Histone H3 Serine 28 Is Essential for Efficient Polycomb-Mediated Gene Repression in Drosophila.

Cell Rep 2015 Jun 21;11(9):1437-45. Epub 2015 May 21.

Institute of Human Genetics, UPR1142 CNRS, 141 Rue de la Cardonille, 34396 Montpellier Cedex 5, France. Electronic address:

View Article
June 2015
4 Reads
3 PubMed Central Citations(source)
7.21 Impact Factor

Topological organization of Drosophila Hox genes using DNA fluorescent in situ hybridization.

Methods Mol Biol 2014 ;1196:103-20

Institut de Génétique Humaine, CNRS UPR-1142, 141 rue de la Cardonille, 34396, Montpellier Cedex 5, France,

View Article
May 2015
1 Read
3 PubMed Central Citations(source)

The role of chromosome domains in shaping the functional genome.

Cell 2015 Mar;160(6):1049-59

Institute of Human Genetics (IGH), 141 rue de la Cardonille, 34396 Montpellier, France. Electronic address:

View Article
March 2015
2 Reads
76 PubMed Central Citations(source)
32.24 Impact Factor

In vivo formaldehyde cross-linking: it is time for black box analysis.

Brief Funct Genomics 2015 Mar 19;14(2):163-5. Epub 2014 Sep 19.

View Article
March 2015
2 Reads
13 PubMed Central Citations(source)
3.67 Impact Factor

Chromatin-driven behavior of topologically associating domains.

J Mol Biol 2015 Feb 2;427(3):608-25. Epub 2014 Oct 2.

Institute of Human Genetics (IGH), UPR 1142, CNRS, 34396 Montpellier, France. Electronic address:

View Article
February 2015
13 Reads
30 PubMed Central Citations(source)
4.33 Impact Factor

Cooperativity, specificity, and evolutionary stability of Polycomb targeting in Drosophila.

Cell Rep 2014 Oct 2;9(1):219-233. Epub 2014 Oct 2.

Institute of Human Genetics, UPR 1142, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France. Electronic address:

View Article
October 2014
3 Reads
22 PubMed Central Citations(source)
7.21 Impact Factor

Modeling epigenome folding: formation and dynamics of topologically associated chromatin domains.

Nucleic Acids Res 2014 Sep 4;42(15):9553-61. Epub 2014 Aug 4.

Laboratoire de Physique, Ecole Normale Supérieure de Lyon, CNRS UMR 5672, Lyon 69007, France

View Article
September 2014
3 Reads
45 PubMed Central Citations(source)
9.11 Impact Factor

Identification of regulators of the three-dimensional polycomb organization by a microscopy-based genome-wide RNAi screen.

Mol Cell 2014 May 3;54(3):485-99. Epub 2014 Apr 3.

Institute of Human Genetics, UPR1142 CNRS, 141 Rue de la Cardonille, 34396 Montpellier Cedex 5, France. Electronic address:

View Article
May 2014
4 Reads
10 PubMed Central Citations(source)
14.02 Impact Factor

Polycomb silencing: from linear chromatin domains to 3D chromosome folding.

Curr Opin Genet Dev 2014 Apr 14;25:30-7. Epub 2014 Jan 14.

Institute of Human Genetics, CNRS UPR 1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France. Electronic address:

View Article
April 2014
9 Reads
26 PubMed Central Citations(source)
7.57 Impact Factor

Chromosomes: now in 3D!

Authors:
Giacomo Cavalli

Nat Rev Mol Cell Biol 2014 Jan 27;15(1). Epub 2013 Nov 27.

Institute of Human Genetics, 141 rue de la Cardonille, 34396 Montpellier, France.

View Article
January 2014
1 Read
2 PubMed Central Citations(source)
36.46 Impact Factor

A RING to rule them all: RING1 as silencer and activator.

Authors:
Giacomo Cavalli

Dev Cell 2014 Jan;28(1):1-2

Institute of Human Genetics, UPR 1142 CNRS, 141 rue de la Cardonille, Montpellier, France. Electronic address:

View Article
January 2014
2 Reads
9.71 Impact Factor

Polycomb domain formation depends on short and long distance regulatory cues.

PLoS One 2013 20;8(2):e56531. Epub 2013 Feb 20.

Institut de Génétique Humaine, Centre National de la Recherche Scientifique, Montpellier, France.

View Article
September 2013
2 Reads
12 PubMed Central Citations(source)
3.23 Impact Factor

PRC2 controls Drosophila oocyte cell fate by repressing cell cycle genes.

Dev Cell 2013 Aug 8;26(4):431-9. Epub 2013 Aug 8.

Institut de Génétique Humaine, CNRS, 141 rue de la Cardonille, Montpellier 34396, France.

View Article
August 2013
2 Reads
16 PubMed Central Citations(source)
9.71 Impact Factor

The 3D genome shapes up for pluripotency.

Cell Stem Cell 2013 Jul;13(1):3-4

Institute of Human Genetics, UPR 1142, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
July 2013
2 Reads
1 PubMed Central Citation(source)

Polycomb controls gliogenesis by regulating the transient expression of the Gcm/Glide fate determinant.

PLoS Genet 2012 27;8(12):e1003159. Epub 2012 Dec 27.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/UDS, Illkirch, France.

View Article
May 2013
4 Reads
3 PubMed Central Citations(source)

Chromosomal domains: epigenetic contexts and functional implications of genomic compartmentalization.

Curr Opin Genet Dev 2013 Apr 14;23(2):197-203. Epub 2013 Feb 14.

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.

View Article
April 2013
2 Reads
26 PubMed Central Citations(source)
7.57 Impact Factor

Functional implications of genome topology.

Nat Struct Mol Biol 2013 Mar;20(3):290-9

Institut de Génétique Humaine, UPR 1142, Centre National de la Recherche Scientifique, Montpellier, France.

View Article
March 2013
3 Reads
123 PubMed Central Citations(source)

Molecular biology. EZH2 goes solo.

Authors:
Giacomo Cavalli

Science 2012 Dec;338(6113):1430-1

Institut de Génétique Humaine, CNRS, 141 rue de la Cardonille, 34396 Montpellier, France.

View Article
December 2012
4 Reads
8 PubMed Central Citations(source)
31.48 Impact Factor

Polycomb: a paradigm for genome organization from one to three dimensions.

Curr Opin Cell Biol 2012 Jun 13;24(3):405-14. Epub 2012 Feb 13.

Institute of Human Genetics, CNRS UPR 1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
June 2012
1 Read
19 PubMed Central Citations(source)
8.47 Impact Factor

Three-dimensional folding and functional organization principles of the Drosophila genome.

Cell 2012 Feb 19;148(3):458-72. Epub 2012 Jan 19.

Institut de Génétique Humaine, UPR 1142, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
February 2012
4 Reads
467 PubMed Central Citations(source)
32.24 Impact Factor

Progressive polycomb assembly on H3K27me3 compartments generates polycomb bodies with developmentally regulated motion.

PLoS Genet 2012 Jan 19;8(1):e1002465. Epub 2012 Jan 19.

Institut de Génétique Humaine, Montpellier, France.

View Article
January 2012
5 Reads
26 PubMed Central Citations(source)

Trithorax group proteins: switching genes on and keeping them active.

Nat Rev Mol Cell Biol 2011 Nov 23;12(12):799-814. Epub 2011 Nov 23.

Institut de Génétique Humaine, CNRS, 141, Rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
November 2011
3 Reads
140 PubMed Central Citations(source)
36.46 Impact Factor

Polycomb group proteins: repression in 3D.

Trends Genet 2011 Nov 25;27(11):454-64. Epub 2011 Jul 25.

Institut de Génétique Humaine, Centre National de la Recherche Scientifique (CNRS) Unité Propre de Recherche 1142, 141, rue de la Cardonille, 34396 Montpellier CEDEX 5, France.

View Article
November 2011
2 Reads
48 PubMed Central Citations(source)
9.92 Impact Factor

Integrated gene regulatory circuits: celebrating the 50(th) anniversary of the operon model.

Mol Cell 2011 Aug;43(4):505-14

Stem Cells and Development, Department of Developmental Biology, Institut Pasteur, CNRS URA 2578, 25 rue du Dr. Roux, 75015 Paris, France.

View Article
August 2011
2 Reads
14.02 Impact Factor

Eukaryotic cells.

Curr Opin Cell Biol 2011 Jun 16;23(3):255-7. Epub 2011 May 16.

View Article
June 2011
3 Reads
8.47 Impact Factor

Rolling ES cells down the Waddington landscape with Oct4 and Sox2.

Cell 2011 Jun;145(6):815-7

Institut de Génétique Humaine, CNRS, 141 rue de la Cardonille, 34396 Montpellier, France.

View Article
June 2011
3 Reads
8 PubMed Central Citations(source)
32.24 Impact Factor

From linear genes to epigenetic inheritance of three-dimensional epigenomes.

Authors:
Giacomo Cavalli

J Mol Biol 2011 May 15;409(1):54-61. Epub 2011 Mar 15.

Institut de Génétique Humaine, CNRS. 141, rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
May 2011
2 Reads
1 PubMed Central Citation(source)
4.33 Impact Factor

A chromatin insulator driving three-dimensional Polycomb response element (PRE) contacts and Polycomb association with the chromatin fiber.

Proc Natl Acad Sci U S A 2011 Feb 24;108(6):2294-9. Epub 2011 Jan 24.

Institut de Génétique Humaine, Centre National de la Recherche Scientifique Unité Propre de Recherche 1142, 34396 Montpellier Cedex 5, France.

View Article
February 2011
3 Reads
47 PubMed Central Citations(source)
9.81 Impact Factor

Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila.

Cell 2011 Jan;144(2):214-26

Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France.

View Article
January 2011
10 Reads
124 PubMed Central Citations(source)
32.24 Impact Factor

The DUBle life of polycomb complexes.

Dev Cell 2010 Jun;18(6):878-80

Institut de Génétique Humaine, CNRS, 141, rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
June 2010
3 Reads
2 PubMed Central Citations(source)
9.71 Impact Factor

Uncovering a tumor-suppressor function for Drosophila polycomb group genes.

Cell Cycle 2010 Jan 4;9(2):215-6. Epub 2010 Jan 4.

View Article
January 2010
4 Reads
2 PubMed Central Citations(source)

Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice.

Development 2009 Nov;136(21):3531-42

Institut de Génétique Humaine, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
November 2009
3 Reads
141 PubMed Central Citations(source)
6.46 Impact Factor

Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling.

Nat Genet 2009 Oct 13;41(10):1076-82. Epub 2009 Sep 13.

Institut de Génétique Humaine, Centre Nationale de la Recherche Scientifique, Montpellier, France.

View Article
October 2009
2 Reads
40 PubMed Central Citations(source)
29.35 Impact Factor

Genomic interactions: chromatin loops and gene meeting points in transcriptional regulation.

Semin Cell Dev Biol 2009 Sep 24;20(7):849-55. Epub 2009 Jun 24.

Institute of Human Genetics CNRS - UPR 1142, 141 Rue de la Cardonille, 34396 Montpellier, France.

View Article
September 2009
3 Reads
43 PubMed Central Citations(source)
6.26 Impact Factor

Epigenetics and the control of multicellularity. Workshop on chromatin at the nexus of cell division and differentiation.

EMBO Rep 2009 Jan 28;10(1):25-9. Epub 2008 Nov 28.

Institute of Biology, Developmental Genetics, Martin Luther University Halle, Halle, Germany.

View Article
January 2009
4 Reads
9.05 Impact Factor

Polycomb group proteins and long-range gene regulation.

Adv Genet 2008 ;61:45-66

Chromatin and Cell Biology Lab, Institute of Human Genetics, CNRS, 141, rue de la Cardonille, 34396 Montpellier, France.

View Article
November 2008
2 Reads
13 PubMed Central Citations(source)
6.76 Impact Factor

Chromosome kissing.

Authors:
Giacomo Cavalli

Curr Opin Genet Dev 2007 Oct 22;17(5):443-50. Epub 2007 Oct 22.

Institute of Human Genetics, CNRS, 141, rue de la Cardonille, 34396 Montpellier, France.

View Article
October 2007
9 Reads
31 PubMed Central Citations(source)
7.57 Impact Factor

Combinatorial epigenetics, "junk DNA", and the evolution of complex organisms.

Gene 2007 Apr 9;390(1-2):232-42. Epub 2006 Dec 9.

Department of Biological Sciences, Stanford University, Stanford, California 94305, USA.

View Article
April 2007
8 Reads
14 PubMed Central Citations(source)
2.14 Impact Factor

Genome regulation by polycomb and trithorax proteins.

Cell 2007 Feb;128(4):735-45

Institute of Human Genetics, CNRS, 141, rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
February 2007
4 Reads
520 PubMed Central Citations(source)
32.24 Impact Factor

Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions.

Nat Rev Genet 2007 Feb;8(2):104-15

Department Biologie II, Ludwig-Maximilians Universität, Grosshadernerstr. 2, Planegg-Martinsried, Germany.

View Article
February 2007
2 Reads
250 PubMed Central Citations(source)
36.98 Impact Factor

[Polycomb controls the cell fate].

Med Sci (Paris) 2006 Dec;22(12):1033-5

View Article
December 2006
4 Reads
0.52 Impact Factor

Mapping the distribution of chromatin proteins by ChIP on chip.

Methods Enzymol 2006 ;410:316-41

Chromatin and Cell Biology Lab, Institute of Human Genetics- CNRS, Montpellier, Cedex 05, France.

View Article
December 2006
5 Reads
19 PubMed Central Citations(source)
2.09 Impact Factor

From genetics to epigenetics: the tale of Polycomb group and trithorax group genes.

Chromosome Res 2006 ;14(4):363-75

Institute of Human Genetics, CNRS, 141, rue de la Cardonille, 34396, Montpellier Cedex 5, France.

View Article
August 2006
3 Reads
66 PubMed Central Citations(source)
2.48 Impact Factor

PRE-mediated bypass of two Su(Hw) insulators targets PcG proteins to a downstream promoter.

Dev Cell 2006 Jul;11(1):117-24

Institute of Human Genetics, Centre National de la Recherche Scientifique, 141 rue de la Cardonille, F-34396 Montpellier Cedex 5, France.

View Article
July 2006
3 Reads
32 PubMed Central Citations(source)
9.71 Impact Factor

Chromosomal distribution of PcG proteins during Drosophila development.

PLoS Biol 2006 Jun 20;4(6):e170. Epub 2006 Apr 20.

Institute of Human Genetics, Centre national de la recherche scientifique (CNRS), Montpellier Cedex, France.

View Article
June 2006
3 Reads
94 PubMed Central Citations(source)

Cellular memory and dynamic regulation of polycomb group proteins.

Curr Opin Cell Biol 2006 Jun 2;18(3):275-83. Epub 2006 May 2.

Institute of Human Genetics, CNRS, 141, rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
June 2006
2 Reads
43 PubMed Central Citations(source)
8.47 Impact Factor

Chromatin and epigenetics in development: blending cellular memory with cell fate plasticity.

Authors:
Giacomo Cavalli

Development 2006 Jun 3;133(11):2089-94. Epub 2006 May 3.

Institute of Human Genetics, CNRS, Montpellier, France.

View Article
June 2006
2 Reads
18 PubMed Central Citations(source)
6.46 Impact Factor

The role of polycomb group proteins in cell cycle regulation during development.

Cell Cycle 2006 Jun 1;5(11):1189-97. Epub 2006 Jun 1.

Institute of Human Genetics, CNRS, Montpellier, France.

View Article
June 2006
1 Read
33 PubMed Central Citations(source)

RNAi components are required for nuclear clustering of Polycomb group response elements.

Cell 2006 Mar;124(5):957-71

Institute of Human Genetics, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

View Article
March 2006
4 Reads
97 PubMed Central Citations(source)
32.24 Impact Factor

Polycomb group-dependent Cyclin A repression in Drosophila.

Genes Dev 2006 Feb;20(4):501-13

Institute of Human Genetics, Centre National de la Recherche Scientifique, 34396 Montpellier Cedex 5, France.

View Article
February 2006
2 Reads
22 PubMed Central Citations(source)
10.80 Impact Factor

[Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1].

Med Sci (Paris) 2005 Aug-Sep;21(8-9):689-91

Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

View Article
December 2005
2 Reads
0.52 Impact Factor

Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila.

Prog Mol Subcell Biol 2005 ;38:31-63

Institute of Human Genetics, CNRS, 34396 Montpellier Cedex 5, France.

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August 2005
3 Reads
5 PubMed Central Citations(source)

The epigenome network of excellence.

PLoS Biol 2005 May 17;3(5):e177. Epub 2005 May 17.

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May 2005
3 Reads
2 PubMed Central Citations(source)

Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1.

Nature 2005 Mar;434(7032):533-8

Institute of Human Genetics, CNRS, 141 rue de la Cardonille, F-34396 Montpellier Cedex 5, France.

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March 2005
3 Reads
51 PubMed Central Citations(source)
42.35 Impact Factor

Interaction between the GAGA factor and Mod(mdg4) proteins promotes insulator bypass in Drosophila.

Proc Natl Acad Sci U S A 2004 Oct 1;101(41):14806-11. Epub 2004 Oct 1.

Department of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, Moscow 117334, Russia.

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October 2004
2 Reads
28 PubMed Central Citations(source)
9.81 Impact Factor

Engrailed and polyhomeotic maintain posterior cell identity through cubitus-interruptus regulation.

Dev Biol 2004 Aug;272(2):522-35

Institut de Génétique Humaine, UPR1142, Montpellier, Herault, France.

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August 2004
2 Reads
17 PubMed Central Citations(source)
3.55 Impact Factor

Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line.

Mol Cell Biol 2004 Aug;24(15):6742-50

Institute of Molecular Genetics of RAS, Kurchatov sq., 2, Moscow 123182, Russia.

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August 2004
2 Reads
71 PubMed Central Citations(source)
4.78 Impact Factor

Combined immunostaining and FISH analysis of polytene chromosomes.

Methods Mol Biol 2004 ;247:289-303

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February 2004
2 Reads
26 PubMed Central Citations(source)

Chromatin inheritance upon Zeste-mediated Brahma recruitment at a minimal cellular memory module.

EMBO J 2004 Feb 12;23(4):857-68. Epub 2004 Feb 12.

Institute of Human Genetics, CNRS, Montpellier Cedex 5, France.

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February 2004
2 Reads
29 PubMed Central Citations(source)
10.43 Impact Factor

Inheritance of Polycomb-dependent chromosomal interactions in Drosophila.

Genes Dev 2003 Oct;17(19):2406-20

Institute of Human Genetics, Centre National de la Recherche Scientifique, 34396 Montpellier 5, France.

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October 2003
2 Reads
68 PubMed Central Citations(source)
10.80 Impact Factor

Identification and characterization of polyhomeotic PREs and TREs.

Dev Biol 2003 Sep;261(2):426-42

Institut de Génétique Humaine, C.N.R.S.-U.P.R. 1142, 141 rue de la Cardonille, 34396 5, Montpellier Cedex, France.

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September 2003
2 Reads
18 PubMed Central Citations(source)
3.55 Impact Factor

Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila.

Proc Natl Acad Sci U S A 2003 Aug 22;100(16):9428-33. Epub 2003 Jul 22.

Department of Genetics and Biostatistics Division, Yale University School of Medicine, New Haven, CT 06520, USA.

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August 2003
3 Reads
28 PubMed Central Citations(source)
9.81 Impact Factor

SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development.

Dev Biol 2003 Jan;253(2):291-308

Department of Biology, Syracuse University, Syracuse, NY 13244-1270, USA.

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January 2003
3 Reads
23 PubMed Central Citations(source)
3.55 Impact Factor

Chromatin as a eukaryotic template of genetic information.

Authors:
Giacomo Cavalli

Curr Opin Cell Biol 2002 Jun;14(3):269-78

Institut de Génétique Humaine-CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

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June 2002
5 Reads
6 PubMed Central Citations(source)
8.47 Impact Factor

The MYST domain acetyltransferase Chameau functions in epigenetic mechanisms of transcriptional repression.

Curr Biol 2002 Apr;12(9):762-6

Laboratoire de Génétique et Physiologie du Développement, Institut de Biologie du Développement de Marseille, CNRS/INSERM/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, 13288 Marseille Cedex 9, France.

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April 2002
11 Reads
30 PubMed Central Citations(source)
9.57 Impact Factor

Epigenetic inheritance of active chromatin after removal of the main transactivator.

Authors:
G Cavalli R Paro

Science 1999 Oct;286(5441):955-8

Zentrum für Molekulare Biologie (ZMBH), Universität of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.

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October 1999
2 Reads
67 PubMed Central Citations(source)
31.48 Impact Factor

Heritable chromatin states induced by the Polycomb and trithorax group genes.

Novartis Found Symp 1998 ;214:51-61; discussion 61-6, 104-13

Zentrum für Molekular Biologie der Universität Heidelberg, D-69120 Heidelberg, Germany.

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June 1998
1 Read
10 PubMed Central Citations(source)

The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis.

Authors:
G Cavalli R Paro

Cell 1998 May;93(4):505-18

ZMBH, Universität Heidelberg, Germany.

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May 1998
2 Reads
98 PubMed Central Citations(source)
32.24 Impact Factor

Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression.

EMBO J 1997 Jun;16(12):3621-32

ZMBH, University of Heidelberg, Germany.

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June 1997
3 Reads
78 PubMed Central Citations(source)
10.43 Impact Factor

Inactivation of topoisomerases affects transcription-dependent chromatin transitions in rDNA but not in a gene transcribed by RNA polymerase II.

EMBO J 1996 Feb;15(3):590-7

Institut für Zellbiologie, Zurich, Switzerland.

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February 1996
5 Reads
12 PubMed Central Citations(source)
10.43 Impact Factor

Chromatin transitions during activation and repression of galactose-regulated genes in yeast.

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G Cavalli F Thoma

EMBO J 1993 Dec;12(12):4603-13

Institut für Zellbiologie, ETH-Hönggerberg, Zürich, Switzerland.

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December 1993
2 Reads
43 PubMed Central Citations(source)
10.43 Impact Factor
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