Ghulam J Mufti

Ghulam J Mufti

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Ghulam J Mufti

Ghulam J Mufti

Publications by authors named "Ghulam J Mufti"

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The Case for Upfront HLA-Matched Unrelated Donor Hematopoietic Stem Cell Transplantation as a Curative Option for Adult Acquired Severe Aplastic Anemia.

Biol Blood Marrow Transplant 2019 Sep 24;25(9):e277-e284. Epub 2019 May 24.

Department of Haematological Medicine, King's College Hospital/King's College London, London, UK.

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http://dx.doi.org/10.1016/j.bbmt.2019.05.012DOI Listing
September 2019

Novel ADA2 mutation presenting with neutropenia, lymphopenia and bone marrow failure in patients with deficiency in adenosine deaminase 2 (DADA2).

Br J Haematol 2019 Aug 28;186(3):e60-e64. Epub 2019 Mar 28.

Department of Immunological Medicine, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, School of medicine, King's College London, King's Health Partners, King's College Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1111/bjh.15896DOI Listing
August 2019

Clinical efficacy of rituximab in the treatment of pemphigus vulgaris: A 10-year follow-up.

J Oral Pathol Med 2019 Aug 13. Epub 2019 Aug 13.

Department of Dermatology, King's College Hospital, London, UK.

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http://dx.doi.org/10.1111/jop.12948DOI Listing
August 2019

Reduced Relapse Incidence with FLAMSA-RIC Compared with Busulfan/Fludarabine for Acute Myelogenous Leukemia Patients in First or Second Complete Remission: A Study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

Biol Blood Marrow Transplant 2018 11 7;24(11):2224-2232. Epub 2018 Aug 7.

Hematology Division and Bone Marrow Transplantation, Chaim Sheba Medical Center, Tel-Hashomer and Tel Aviv University, Tel-Aviv, Israel; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation, Paris, France.

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http://dx.doi.org/10.1016/j.bbmt.2018.07.007DOI Listing
November 2018

Pre-symptomatic (Baseline) computed tomography predicts invasive pulmonary aspergillosis in high-risk adult haemato-oncology patients.

Br J Haematol 2018 09 24;182(5):723-727. Epub 2017 Jul 24.

Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1111/bjh.14858DOI Listing
September 2018

Clonal hematopoiesis in patients with multiple myeloma undergoing autologous stem cell transplantation.

Leukemia 2018 09 19;32(9):2020-2024. Epub 2018 Jul 19.

Department of Haematological Medicine, The Rayne Institute, King's College London, London, UK.

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http://dx.doi.org/10.1038/s41375-018-0208-8DOI Listing
September 2018

Diagnostic algorithm for lower-risk myelodysplastic syndromes.

Leukemia 2018 08 26;32(8):1679-1696. Epub 2018 Jun 26.

Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41375-018-0173-2DOI Listing
August 2018

Somatic Mutations in Aplastic Anemia.

Hematol Oncol Clin North Am 2018 08 5;32(4):595-607. Epub 2018 Jun 5.

Department of Haematological Medicine, King's College Hospital, King's College London, Denmark Hill, London SE59RS, UK. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2018.03.002DOI Listing
August 2018

miR-181c-BRK1 axis plays a key role in actin cytoskeleton-dependent T cell function.

J Leukoc Biol 2018 05 14;103(5):855-866. Epub 2018 Apr 14.

Department of Haemato-Oncology, Division of Cancer Studies, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/JLB.1A0817-325RRDOI Listing
May 2018

The Use of PARP Inhibitors in Cancer Therapy: Use as Adjuvant with Chemotherapy or Radiotherapy, Use as a Single Agent in Susceptible Patients, and Techniques Used to Identify Susceptible Patients.

Methods Mol Biol 2017 ;1608:343-370

Department of Haematological Medicine, Kings College London, The Rayne Institute, 123 Coldharbour Lane, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/978-1-4939-6993-7_23DOI Listing
April 2018

Women Administered Standard Dose Imatinib for Chronic Myeloid Leukemia Have Higher Dose-Adjusted Plasma Imatinib and Norimatinib Concentrations Than Men.

Ther Drug Monit 2017 10;39(5):499-504

*Toxicology Unit, Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust; †Department of Haematology, King's College London NHS Foundation Trust; and ‡Statistician, Department of Primary Care and Public Health Sciences, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1097/FTD.0000000000000440DOI Listing
October 2017

FLT3 and JAK2 Mutations in Acute Myeloid Leukemia Promote Interchromosomal Homologous Recombination and the Potential for Copy Neutral Loss of Heterozygosity.

Cancer Res 2017 04 20;77(7):1697-1708. Epub 2017 Jan 20.

Department of Haematological Medicine, King's College London, Leukaemia Sciences Laboratories, The Rayne Institute, London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1678DOI Listing
April 2017

Myelodysplastic syndrome can propagate from the multipotent progenitor compartment.

Haematologica 2017 01 6;102(1):e7-e10. Epub 2016 Oct 6.

Haematopoietic Stem Cell Laboratory, The Francis Crick Institute, Department of Haematological Medicine, London, UK

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http://dx.doi.org/10.3324/haematol.2016.152520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210239PMC
January 2017

Spontaneous myonecrosis in chronic myeloid leukaemia.

Br J Haematol 2016 10 12;175(2):190. Epub 2016 Aug 12.

Department of Haematological Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1111/bjh.14278DOI Listing
October 2016

Baseline cytokine profiling identifies novel risk factors for invasive fungal disease among haematology patients undergoing intensive chemotherapy or haematopoietic stem cell transplantation.

J Infect 2016 09 22;73(3):280-8. Epub 2016 Jun 22.

Department of Haematological Medicine, King's College Hospital NHS Foundation Trust and King's College London, London, SE5 9RS, United Kingdom.

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http://dx.doi.org/10.1016/j.jinf.2016.04.040DOI Listing
September 2016

Randomized Phase III Study of Lenalidomide Versus Placebo in RBC Transfusion-Dependent Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents.

J Clin Oncol 2016 09 27;34(25):2988-96. Epub 2016 Jun 27.

Valeria Santini, University of Florence, Florence, Italy; Antonio Almeida, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal; Aristoteles Giagounidis and Stefanie Gröpper, Marien Hospital Düsseldorf; Norbert Gattermann, Heinrich-Heine-Universität, Düsseldorf; Uwe Platzbecker, Technical University Dresden, Dresden, Germany; Anna Jonasova, Charles University General Hospital, Prague, Czech Republic; Norbert Vey, Centre Régional de Lutte Contre le Cancer, Marseille; Pierre Fenaux, Université Paris, Paris, France; Francis Séguy and Albert Hoenekopp, Celgene International, Boudry, Switzerland; Ghulam J. Mufti, King's College Hospital, London, United Kingdom; Rena Buckstein, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Moshe Mittelman and Ron Ram, Tel Aviv University; Ofer Shpilberg, Assuta Medical Center, Tel Aviv, Israel; Consuelo del Cañizo, Hospital Universitario de Salamanca, Salamanca; Alberto Risueño, Celgene Institute for Translational Research Europe, Seville, Spain; Keiya Ozawa, The University of Tokyo, Tokyo, Japan; Kyle J. MacBeth, Celgene Corporation, San Francisco, CA; and Jianhua Zhong and C.L. Beach, Celgene Corporation, Summit, NJ.

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http://dx.doi.org/10.1200/JCO.2015.66.0118DOI Listing
September 2016

Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis.

PLoS One 2015 22;10(10):e0140483. Epub 2015 Oct 22.

Cancer Sciences Unit (MP824), Somers Cancer Sciences Building, University of Southampton, Southampton, United Kingdom; Department of Life Sciences, University of Bedfordshire, Park Square, Luton, United Kingdom; Department of Haematological Medicine, King's College London School of Medicine, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140483PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619595PMC
June 2016

Autoimmune diseases and myelodysplastic syndromes.

Am J Hematol 2016 May 4;91(5):E280-3. Epub 2016 Apr 4.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1002/ajh.24333DOI Listing
May 2016

SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment.

Nat Commun 2015 Dec 8;6:10004. Epub 2015 Dec 8.

Department of Haematological Medicine, King's College London School of Medicine, London SE5 9NU, UK.

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http://dx.doi.org/10.1038/ncomms10004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686651PMC
December 2015

JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells.

Br J Haematol 2015 Oct 15;171(1):60-73. Epub 2015 Jun 15.

Department of Haematological Medicine, Kings College London, London, UK.

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http://dx.doi.org/10.1111/bjh.13519DOI Listing
October 2015

Chronic relapsing remitting Sweet syndrome--a harbinger of myelodysplastic syndrome.

Br J Haematol 2015 Sep 12;170(5):649-56. Epub 2015 May 12.

Department of Dermatology, King's College Hospital, London, UK.

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http://dx.doi.org/10.1111/bjh.13485DOI Listing
September 2015

A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells.

Genes Chromosomes Cancer 2015 May 23;54(5):288-302. Epub 2015 Feb 23.

Department of Haematological Medicine, Guy's, King's and St. Thomas' School of Medicine, King's College London, The Rayne Institute, London, UK.

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http://dx.doi.org/10.1002/gcc.22242DOI Listing
May 2015

CSNK1A1 mutations and isolated del(5q) abnormality in myelodysplastic syndrome: a retrospective mutational analysis.

Lancet Haematol 2015 May 6;2(5):e212-21. Epub 2015 May 6.

Department of Haematological Medicine, King's College London School of Medicine, Rayne Institute, King's College London, London, UK; Department of Haematology, King's College Hospital, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(15)00050-2DOI Listing
May 2015

Autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation: analysis of 533 adult patients who underwent transplantation at King's College Hospital.

Biol Blood Marrow Transplant 2015 Jan 28;21(1):60-6. Epub 2014 Sep 28.

Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, and King's College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.bbmt.2014.09.009DOI Listing
January 2015

Nonmyeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia.

Biol Blood Marrow Transplant 2014 Nov 10;20(11):1711-6. Epub 2014 Jul 10.

Department of Hematological Medicine, King's College Hospital, London, United Kingdom; Department of Haematological Medicine, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.06.028DOI Listing
November 2014

Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes.

Br J Haematol 2014 Nov 14;167(3):337-45. Epub 2014 Jul 14.

Leukemia Program, Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH, USA.

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http://dx.doi.org/10.1111/bjh.13037DOI Listing
November 2014

Allogeneic haematopoietic stem cell transplantation in myelodysplastic syndromes.

Curr Opin Oncol 2014 Nov;26(6):642-9

Department of Haematology, King's College Hospital, Denmark Hill, London, UK.

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http://dx.doi.org/10.1097/CCO.0000000000000137DOI Listing
November 2014

Successful treatment of aplastic anaemia associated with HIV infection with eltrombopag: implications for a possible immunomodulatory role.

AIDS 2014 Nov;28(18):2786-8

aDepartment of Haematological Medicine, King's College Hospital bKing's College London, London cHIV Medicine Brighton & Sussex University Hospitals NHS Trust, Brighton, UK.

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http://dx.doi.org/10.1097/QAD.0000000000000504DOI Listing
November 2014

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome.

Blood 2014 Oct 18;124(17):2698-704. Epub 2014 Aug 18.

Department of Haematological Medicine, King's College London School of Medicine, London, United Kingdom; and Department of Haematology, King's College Hospital, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2014-05-574889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383793PMC
October 2014

Applying synthetic lethality for the selective targeting of cancer.

N Engl J Med 2014 Oct;371(18):1725-35

From King's College Hospital NHS Foundation Trust, London (D.P.M., G.J.M.); and Moffitt Cancer Center, Tampa, FL (A.L.).

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http://dx.doi.org/10.1056/NEJMra1407390DOI Listing
October 2014

Eltrombopag: a stem cell cookie?

Blood 2014 Mar;123(12):1774-5

KING'S COLLEGE LONDON.

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http://dx.doi.org/10.1182/blood-2014-02-553404DOI Listing
March 2014

Bilateral retinal vasculopathy associated with autosomal dominant dyskeratosis congenita.

Eur J Ophthalmol 2013 Sep-Oct;23(5):772-5. Epub 2013 May 3.

Medical Retina Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.5301/ejo.5000297DOI Listing
February 2014

Haematopoietic stem cell transplantation for acquired aplastic anaemia.

Curr Opin Hematol 2013 Nov;20(6):515-20

aHaematology Department, Kings College Hospital bKings College London, London, UK.

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http://dx.doi.org/10.1097/MOH.0b013e328365af83DOI Listing
November 2013

Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes.

Br J Haematol 2013 Sep 19;162(5):587-605. Epub 2013 Jul 19.

Department of Haematological Medicine, King's College London School of Medicine, London, UK.

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http://dx.doi.org/10.1111/bjh.12435DOI Listing
September 2013

Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome.

Blood 2013 Jul 12;122(4):567-70. Epub 2013 Jun 12.

Department of Haematological Medicine, King's College London, Rayne Institute, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2012-12-471847DOI Listing
July 2013

Myelodysplastic syndromes: who and when in the course of disease to transplant.

Hematology Am Soc Hematol Educ Program 2012 ;2012:49-55

Department of Haematological Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1182/asheducation-2012.1.49DOI Listing
June 2013

SnapShot: Acute myeloid leukemia.

Cancer Cell 2012 Nov;22(5):698-698.e1

Department of Haematological Medicine, King's College London, London SE5 9NU, UK.

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http://dx.doi.org/10.1016/j.ccr.2012.10.017DOI Listing
November 2012

The non-transplant treatment of myelodysplastic syndromes-what's on the horizon?

Semin Hematol 2012 Oct;49(4):350-60

Department of Haematological Medicine, King's College London School of Medicine, London, UK.

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http://dx.doi.org/10.1053/j.seminhematol.2012.07.005DOI Listing
October 2012

Phase II study on combination therapy with CHOP-Zenapax for HTLV-I associated adult T-cell leukaemia/lymphoma (ATLL).

Leuk Res 2012 Jul 29;36(7):857-61. Epub 2011 Dec 29.

Department of Haematological Medicine, King's College Hospital NHS Foundation Trust and King's College London, London, UK.

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http://dx.doi.org/10.1016/j.leukres.2011.12.004DOI Listing
July 2012

Fluorescence-based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells.

Br J Haematol 2012 Jun 20;157(5):564-79. Epub 2012 Mar 20.

Division of Cancer Studies, Department of Haematological Medicine, Kings College London, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2012.09103.xDOI Listing
June 2012

The use of PARP inhibitors in cancer therapy: use as adjuvant with chemotherapy or radiotherapy; use as a single agent in susceptible patients; techniques used to identify susceptible patients.

Methods Mol Biol 2011 ;780:239-66

Department of Haematological Medicine, The Rayne Institute, Kings College London, Denmark Hill Campus, London, UK.

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http://dx.doi.org/10.1007/978-1-61779-270-0_15DOI Listing
January 2012

Rituximab for the treatment of corticosteroid-refractory pemphigus vulgaris with oral and skin manifestations.

J Oral Pathol Med 2011 Sep 9;40(8):616-20. Epub 2011 Mar 9.

Department of Dermatology, King's College Hospital, London, UK.

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http://dx.doi.org/10.1111/j.1600-0714.2011.01017.xDOI Listing
September 2011

TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression.

J Clin Oncol 2011 May 25;29(15):1971-9. Epub 2011 Apr 25.

Center for Experimental Hematology M54, Karolinska Institutet, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1200/JCO.2010.31.8576DOI Listing
May 2011

The Myelodysplastic Syndromes (MDS) Foundation: a retrospective analysis of a nonprofit foundation.

Leuk Res 2011 Mar 23;35(3):283-5. Epub 2010 Oct 23.

Department of Pathology, University of Rochester Medical Center, Rochester, NY, USA. john

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http://dx.doi.org/10.1016/j.leukres.2010.09.023DOI Listing
March 2011