Gethin P Thomas

Gethin P Thomas

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Gethin P Thomas

Gethin P Thomas

Publications by authors named "Gethin P Thomas"

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Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.

Arthritis Rheumatol 2018 02 29;70(2):255-265. Epub 2017 Dec 29.

Queensland University of Technology and Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://doi.wiley.com/10.1002/art.40369
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http://dx.doi.org/10.1002/art.40369DOI Listing
February 2018

Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis.

BMC Musculoskelet Disord 2017 05 30;18(1):228. Epub 2017 May 30.

Mater Research Institute-The University of Queensland, Faculty of Medicine, Translational Research Institute, 37 Kent St, Woolloongabba, QLD, 4102, Australia.

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http://bmcmusculoskeletdisord.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s12891-017-1600-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450150PMC
May 2017

Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis.

Ann Rheum Dis 2017 Jan 28;76(1):261-269. Epub 2016 Apr 28.

Queensland University of Technology, Institute for Health and Biomedical Innovation, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1136/annrheumdis-2015-208677DOI Listing
January 2017

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.

PLoS One 2015 10;10(4):e0122650. Epub 2015 Apr 10.

Academic Endocrine Unit, Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Oxford, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393098PMC
March 2016

Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes.

Arthritis Res Ther 2016 Jan 29;18:35. Epub 2016 Jan 29.

The University of Queensland Diamantina Institute, Translational Research Institute, 37 Kent Street, Woolloongabba, QLD, 4102, Australia.

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http://dx.doi.org/10.1186/s13075-015-0805-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734853PMC
January 2016

ERAP2 functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers.

Ann Rheum Dis 2015 Nov 18;74(11):2092-5. Epub 2015 Jun 18.

University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

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http://dx.doi.org/10.1136/annrheumdis-2015-207467DOI Listing
November 2015

Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progression.

BMC Musculoskelet Disord 2015 Nov 26;16:368. Epub 2015 Nov 26.

The University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

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http://dx.doi.org/10.1186/s12891-015-0823-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662039PMC
November 2015

Confluence-Induced Squamous Differentiation Is Not Accompanied by Changes in H3K27me3 Repressive Epigenetic Mark.

J Invest Dermatol 2015 Oct 4;135(10):2446-2454. Epub 2015 May 4.

The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.175DOI Listing
October 2015

Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing.

Nat Methods 2015 Apr 9;12(4):339-42. Epub 2015 Mar 9.

1] Garvan Institute of Medical Research, Sydney, Australia. [2] St Vincents Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1038/nmeth.3321DOI Listing
April 2015

Rorα deficiency and decreased adiposity are associated with induction of thermogenic gene expression in subcutaneous white adipose and brown adipose tissue.

Am J Physiol Endocrinol Metab 2015 01 25;308(2):E159-71. Epub 2014 Nov 25.

Obesity Research Centre, Institute for Molecular Bioscience, University of Queensland, St. Lucia, Queensland, Australia;

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http://dx.doi.org/10.1152/ajpendo.00056.2014DOI Listing
January 2015

Resveratrol does not benefit patients with nonalcoholic fatty liver disease.

Clin Gastroenterol Hepatol 2014 Dec 25;12(12):2092-103.e1-6. Epub 2014 Feb 25.

University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute, Brisbane, Australia; Department of Nutrition and Dietetics, Princess Alexandra Hospital, Brisbane, Australia; Mater Medical Research Institute, Brisbane, Australia.

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https://espace.library.uq.edu.au/view/UQ:327406/UQ327406_OA.
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http://linkinghub.elsevier.com/retrieve/pii/S154235651400309
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http://dx.doi.org/10.1016/j.cgh.2014.02.024DOI Listing
December 2014

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration.

World J Gastroenterol 2014 Dec;20(47):17851-62

Katharine M Irvine, Richard Skoien, Michelle Melino, Andrew D Clouston, Elizabeth E Powell, Centre for Liver Disease Research, School of Medicine, The University of Queensland, Translational Research Institute, Brisbane 4102, Australia.

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http://dx.doi.org/10.3748/wjg.v20.i47.17851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273135PMC
December 2014

Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.

J Bone Miner Res 2013 Dec;28(12):2436-48

Bone Cell Biology Group, Centre for Orthopaedic & Trauma Research, Discipline of Orthopaedics and Trauma, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.1002/jbmr.2003DOI Listing
December 2013

Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes.

BMC Musculoskelet Disord 2013 Dec 15;14:354. Epub 2013 Dec 15.

The University of Queensland Diamantina Institute, Translational Research Institute, 37 Kent St, Woolloongabba, QLD 4102, Australia.

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http://dx.doi.org/10.1186/1471-2474-14-354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878669PMC
December 2013

Transgenic muscle-specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism, and endurance.

Mol Endocrinol 2013 Nov 24;27(11):1897-917. Epub 2013 Sep 24.

The University of Queensland, Institute for Molecular Bioscience, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1210/me.2013-1205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427836PMC
November 2013

Ski overexpression in skeletal muscle modulates genetic programs that control susceptibility to diet-induced obesity and insulin signaling.

Obesity (Silver Spring) 2012 Nov 19;20(11):2157-67. Epub 2012 Apr 19.

The University of Queensland, Obesity Research Centre, Institute for Molecular Bioscience, Queensland, Australia.

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http://dx.doi.org/10.1038/oby.2012.101DOI Listing
November 2012

Macrophage secretory products induce an inflammatory phenotype in hepatocytes.

World J Gastroenterol 2012 Apr;18(15):1732-44

Centre for Liver Disease Research, School of Medicine, The University of Queensland, Princess Alexandra Hospital, Brisbane 4102, Queensland, Australia.

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http://dx.doi.org/10.3748/wjg.v18.i15.1732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332286PMC
April 2012

Potential of genome-wide association study data to contribute to better treatments: examples from ankylosing spondylitis.

Authors:
Gethin P Thomas

Per Med 2011 Nov;8(6):599-601

University of Queensland Diamantina Institute, Princess Alexandra Hospital, Woolloongabba, QLD 4102, Australia.

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http://dx.doi.org/10.2217/pme.11.63DOI Listing
November 2011

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.

Nat Genet 2011 Jul 10;43(8):761-7. Epub 2011 Jul 10.

Medical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/ng.873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640413PMC
July 2011

Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia.

PLoS Genet 2011 Mar 24;7(3):e1002027. Epub 2011 Mar 24.

University of Queensland Diamantina Institute, Princess Alexandra Hospital, Woolloongabba, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1002027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063761PMC
March 2011

Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese.

Ann Rheum Dis 2011 Feb 10;70(2):289-92. Epub 2010 Nov 10.

The University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2010.133322
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http://dx.doi.org/10.1136/ard.2010.133322DOI Listing
February 2011

Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor.

Lab Invest 2010 Nov 26;90(11):1594-603. Epub 2010 Jul 26.

Epithelial Pathobiology Group, Diamantina Institute, Princess Alexandra Hospital, University of Queensland, Woolloongabba, Queensland, Australia.

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http://dx.doi.org/10.1038/labinvest.2010.131DOI Listing
November 2010

Genomics of ankylosing spondylitis.

Discov Med 2010 Sep;10(52):263-71

University of Queensland Diamantina Institute, Woolloongabba, Queensland, 4102, Australia.

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September 2010

Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.

Mol Cancer Ther 2010 Aug 3;9(8):2430-9. Epub 2010 Aug 3.

Diamantina Institute, The University of Queensland, Princess Alexandra Hospital, Ipswich Road, Brisbane, Queensland, Australia.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-10-0258DOI Listing
August 2010

Genetics and genomics of ankylosing spondylitis.

Immunol Rev 2010 Jan;233(1):162-80

Diamantina Institute of Cancer, Immunology and Metabolic Medicine, Princess Alexandra Hospital, Qld, Australia.

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http://dx.doi.org/10.1111/j.0105-2896.2009.00852.xDOI Listing
January 2010

Vitamin D action and regulation of bone remodeling: suppression of osteoclastogenesis by the mature osteoblast.

J Bone Miner Res 2006 Oct;21(10):1618-26

Bone Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, New South Wales, Australia.

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http://doi.wiley.com/10.1359/jbmr.060714
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http://dx.doi.org/10.1359/jbmr.060714DOI Listing
October 2006

Characterization of osteocrin expression in human bone.

J Histochem Cytochem 2005 Oct 27;53(10):1181-7. Epub 2005 May 27.

Cambridge University School of Clinical Medicine, Addenbrooke's Hospital, UK.

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http://journals.sagepub.com/doi/10.1369/jhc.4C6561.2005
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http://dx.doi.org/10.1369/jhc.4C6561.2005DOI Listing
October 2005

Hypothalamic Y2 receptors regulate bone formation.

J Clin Invest 2002 Apr;109(7):915-21

Bone and Mineral Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, Australia.

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http://dx.doi.org/10.1172/JCI14588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150931PMC
April 2002