Publications by authors named "Gesine Bug"

92 Publications

Efficacy of UVC-treated, pathogen-reduced platelets versus untreated platelets: a randomized controlled non-inferiority trial.

Authors:
Veronika Brixner Gesine Bug Petra Pohler Doris Krämer Bernd Metzner Andreas Voß Jochen Casper Ulrich Ritter Stefan Klein Nael Alakel Rudolf Peceny Hans G Derigs Frank Stegelmann Martin Wolf Hubert Schrezenmeier Thomas Thiele Erhard Seifried Hans-Hermann Kapels Andrea Döscher Eduard K Petershofen Thomas H Müller Axel Seltsam

Haematologica 2021 Feb 4. Epub 2021 Feb 4.

German Red Cross Blood Service NSTOB, Springe, Germany; Bavarian Red Cross Blood Service, Nuremberg.

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February 2021

Defining the Role of Donor Lymphocyte Infusion in High-Risk Hematologic Malignancies.

Authors:
Christoph Schmid Jürgen Kuball Gesine Bug

J Clin Oncol 2021 Feb 12;39(5):397-418. Epub 2021 Jan 12.

Department of Medicine 2, Goethe University, Frankfurt am Main, Germany.

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February 2021

Second- and third-generation tyrosine kinase inhibitors for Philadelphia-positive adult acute lymphoblastic leukemia relapsing post allogeneic stem cell transplantation-a registry study on behalf of the EBMT Acute Leukemia Working Party.

Authors:
Klaus Hirschbühl Myriam Labopin Mohamed Houhou Ludovic Gabellier Hélène Labussière-Wallet Bruno Lioure Dietrich Beelen Jan Cornelissen Gerald Wulf Pavel Jindra Hervé Tilly Jakob Passweg Riita Niittyvuopio Gesine Bug Christoph Schmid Arnon Nagler Sebastian Giebel Mohamad Mohty

Bone Marrow Transplant 2020 Dec 9. Epub 2020 Dec 9.

Service d'Hématologie et de Thérapie cellulaire, Hôpital Saint Antoine, ALWP Office (EBMT), Paris, France.

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December 2020

Treatment of myeloid malignancies relapsing after allogeneic hematopoietic stem cell transplantation with venetoclax and hypomethylating agents-a retrospective multicenter analysis on behalf of the German Cooperative Transplant Study Group.

Authors:
Esther Schuler Eva-Maria Wagner-Drouet Salem Ajib Gesine Bug Martina Crysandt Sabine Dressler Andreas Hausmann Daniela Heidenreich Klaus Hirschbühl Matthias Hoepting Edgar Jost Jennifer Kaivers Stefan Klein Michael Koldehoff Lambros Kordelas Oliver Kriege Lutz P Müller Christina Rautenberg Judith Schaffrath Christoph Schmid Daniel Wolff Rainer Haas Martin Bornhäuser Thomas Schroeder Guido Kobbe

Ann Hematol 2020 Nov 16. Epub 2020 Nov 16.

Department of Hematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Medical Faculty, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.

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November 2020

A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia.

Authors:
Fabian Lang Lydia Wunderle Susanne Badura Eberhard Schleyer Monika Brüggemann Hubert Serve Susanne Schnittger Nicola Gökbuget Heike Pfeifer Sebastian Wagner Kevin Ashelford Gesine Bug Oliver G Ottmann

BMC Pharmacol Toxicol 2020 09 29;21(1):70. Epub 2020 Sep 29.

School of Medicine, Cardiff University, Cardiff, Wales, UK.

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September 2020

Evaluation of Trends and Prognosis Over Time in Patients with AML Relapsing After Allogeneic Hematopoietic Cell Transplant Reveals Improved Survival for Young Patients in Recent Years.

Authors:
Ali Bazarbachi Christoph Schmid Myriam Labopin Dietrich Beelen Igor Wolfgang Blau Victoria Potter Riitta Niittyvuopio Gerard Socié Didier Blaise Jaime Sanz Fabio Ciceri Iman Abou Dalle Alexandros Spyridonidis Gesine Bug Jordi Esteve Bipin N Savani Arnon Nagler Mohamad Mohty

Clin Cancer Res 2020 Dec 28;26(24):6475-6482. Epub 2020 Sep 28.

Department of Clinical Hematology and Cellular Therapy, Saint-Antoine Hospital, INSERM UMR 938 and Sorbonne University, Paris, France.

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December 2020

Impact of Clostridioides difficile infection on the outcome of patients receiving a hematopoietic stem cell transplantation.

Authors:
Sarah Weber Sebastian Scheich Aaron Magh Sebastian Wolf Julius C Enßle Uta Brunnberg Claudia Reinheimer Thomas A Wichelhaus Volkhard A J Kempf Johanna Kessel Maria J G T Vehreschild Hubert Serve Gesine Bug Björn Steffen Michael Hogardt

Int J Infect Dis 2020 Oct 12;99:428-436. Epub 2020 Aug 12.

University Center for Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main, Germany; Institute of Medical Microbiology and Infection Control, University Hospital Frankfurt, Frankfurt am Main, Germany; University Center of Competence for Infection Control, State of Hesse, Germany.

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October 2020

Measurable residual disease (MRD) testing for acute leukemia in EBMT transplant centers: a survey on behalf of the ALWP of the EBMT.

Authors:
Arnon Nagler Frédéric Baron Myriam Labopin Emmanuel Polge Jordi Esteve Ali Bazarbachi Eolia Brissot Gesine Bug Fabio Ciceri Sebastian Giebel Maria H Gilleece Norbert-Claude Gorin Francesco Lanza Zinaida Peric Annalisa Ruggeri Jaime Sanz Bipin N Savani Christoph Schmid Roni Shouval Alexandros Spyridonidis Jurjen Versluis Mohamad Mohty

Bone Marrow Transplant 2021 Jan 28;56(1):218-224. Epub 2020 Jul 28.

EBMT Paris Study Office/CEREST-TC, Paris, France.

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January 2021

Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With -Internal Tandem Duplication Mutation (SORMAIN).

Authors:
Andreas Burchert Gesine Bug Lea V Fritz Jürgen Finke Matthias Stelljes Christoph Röllig Ellen Wollmer Ralph Wäsch Martin Bornhäuser Tobias Berg Fabian Lang Gerhard Ehninger Hubert Serve Robert Zeiser Eva-Maria Wagner Nicolaus Kröger Christine Wolschke Michael Schleuning Katharina S Götze Christoph Schmid Martina Crysandt Eva Eßeling Dominik Wolf Ying Wang Alexandra Böhm Christian Thiede Torsten Haferlach Christian Michel Wolfgang Bethge Thomas Wündisch Christian Brandts Susanne Harnisch Michael Wittenberg Heinz-Gert Hoeffkes Susanne Rospleszcz Alexander Burchardt Andreas Neubauer Markus Brugger Konstantin Strauch Carmen Schade-Brittinger Stephan K Metzelder

J Clin Oncol 2020 09 16;38(26):2993-3002. Epub 2020 Jul 16.

Department of Internal Medicine, Hematology, Oncology and Immunology, Philipps University Marburg and University Hospital Gießen and Marburg, Campus Marburg, Marburg, Germany.

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September 2020

Management of patients with acute leukemia during the COVID-19 outbreak: practical guidelines from the acute leukemia working party of the European Society for Blood and Marrow Transplantation.

Authors:
Eolia Brissot Myriam Labopin Frédéric Baron Ali Bazarbachi Gesine Bug Fabio Ciceri Jordi Esteve Sebastian Giebel Maria H Gilleece Norbert-Claude Gorin Francesco Lanza Zinaida Peric Annalisa Ruggeri Jaime Sanz Bipin N Savani Christoph Schmid Roni Shouval Alexandros Spyridonidis Jurjen Versluis Arnon Nagler Mohamad Mohty

Bone Marrow Transplant 2020 Jun 11. Epub 2020 Jun 11.

Saint-Antoine Hospital, Sorbonne University, AP-HP, INSERM UMRs 938, Paris, France.

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June 2020

Reducing the red blood cell transfusion threshold from 8·0 g/dl to 7·0 g/dl in acute myeloid leukaemia patients undergoing induction chemotherapy reduces transfusion rates without adversely affecting patient outcome.

Authors:
Olivier Ballo Philine Fleckenstein Fagr Eladly Eva-Maria Kreisel Jan Stratmann Erhard Seifried Markus Müller Hubert Serve Gesine Bug Halvard Bonig Christian H Brandts Fabian Finkelmeier

Vox Sang 2020 Oct 28;115(7):570-578. Epub 2020 Apr 28.

Department of Medicine, Gastroenterology, Hepatology and Endocrinology, University Hospital, Goethe University, Frankfurt/Main, Germany.

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October 2020

Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

Authors:
Ali Bazarbachi Gesine Bug Frederic Baron Eolia Brissot Fabio Ciceri Iman Abou Dalle Hartmut Döhner Jordi Esteve Yngvar Floisand Sebastian Giebel Maria Gilleece Norbert-Claude Gorin Elias Jabbour Mahmoud Aljurf Hagop Kantarjian Mohamed Kharfan-Dabaja Myriam Labopin Francesco Lanza Florent Malard Zinaida Peric Thomas Prebet Farhad Ravandi Annalisa Ruggeri Jaime Sanz Christoph Schmid Roni Shouval Alexandros Spyridonidis Jurjen Versluis Norbert Vey Bipin N Savani Arnon Nagler Mohamad Mohty

Haematologica 2020 Jun 2;105(6):1507-1516. Epub 2020 Apr 2.

Sorbonne Universités, UPMC University of Paris 06, INSERM, Centre de Recherche Saint-Antoine (CRSA), Hematology Department, AP-HP, Saint Antoine Hospital, Paris, France.

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June 2020

Correction: Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients.

Authors:
Alexandros Spyridonidis Myriam Labopin Bipin N Savani Riitta Niittyvuopio Didier Blaise Charles Craddock Gerard Socié Uwe Platzbecker Dietrich Beelen Noel Milpied Jan J Cornelissen Arnold Ganser Anne Huynh Laimonas Griskevicius Sebastian Giebel Mahmoud Aljurf Eolia Brissot Florent Malard Jordi Esteve Zinaida Peric Frédéric Baron Annalisa Ruggeri Christoph Schmid Maria Gilleece Norbert-Claude Gorin Francesco Lanza Roni Shouval Jurjen Versluis Gesine Bug Yngvar Fløisand Fabio Ciceri Jamie Sanz Ali Bazarbachi Arnon Nagler Mohamad Mohty

Bone Marrow Transplant 2020 Jun;55(6):1213

Service d' Hématologie Clinique et Thérapie Cellulaire, Hospital Saint-Antoine, Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA), Paris, France.

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June 2020

Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients.

Authors:
Alexandros Spyridonidis Myriam Labopin Bipin N Savani Riitta Niittyvuopio Didier Blaise Charles Craddock Gerard Socié Uwe Platzbecker Dietrich Beelen Noel Milpied Jan J Cornelissen Arnold Ganser Anne Huynh Laimonas Griskevicius Sebastian Giebel Mahmoud Aljurf Eolia Brissot Florent Malard Jordi Esteve Zinaida Peric Frédéric Baron Annalisa Ruggeri Christoph Schmid Maria Gilleece Norbert-Claude Gorin Francesco Lanza Roni Shouval Jurjen Versluis Gesine Bug Yngvar Fløisand Fabio Ciceri Jamie Sanz Ali Bazarbachi Arnon Nagler Mohamad Mohty

Bone Marrow Transplant 2020 06 29;55(6):1114-1125. Epub 2020 Jan 29.

Service d' Hématologie Clinique et Thérapie Cellulaire, Hospital Saint-Antoine, Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA), Paris, France.

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June 2020

External validation of models for KIR2DS1/KIR3DL1-informed selection of hematopoietic cell donors fails.

Authors:
Johannes Schetelig Henning Baldauf Falk Heidenreich Carolin Massalski Sandra Frank Jürgen Sauter Matthias Stelljes Francis Ayuketang Ayuk Wolfgang A Bethge Gesine Bug Stefan Klein Sarah Wendler Vinzenz Lange Liesbeth C de Wreede Daniel Fürst Guido Kobbe Hellmut D Ottinger Dietrich W Beelen Joannis Mytilineos Katharina Fleischhauer Alexander H Schmidt Martin Bornhäuser

Blood 2020 04;135(16):1386-1395

Department of Internal Medicine I, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.

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April 2020

Children and Adults with Refractory Acute Graft-versus-Host Disease Respond to Treatment with the Mesenchymal Stromal Cell Preparation "MSC-FFM"-Outcome Report of 92 Patients.

Authors:
Halvard Bonig Zyrafete Kuçi Selim Kuçi Shahrzad Bakhtiar Oliver Basu Gesine Bug Mike Dennis Johann Greil Aniko Barta Krisztián M Kállay Peter Lang Giovanna Lucchini Raj Pol Ansgar Schulz Karl-Walter Sykora Irene Teichert von Luettichau Grit Herter-Sprie Mohammad Ashab Uddin Phil Jenkin Abdulrahman Alsultan Jochen Buechner Jerry Stein Agnes Kelemen Andrea Jarisch Jan Soerensen Emilia Salzmann-Manrique Martin Hutter Richard Schäfer Erhard Seifried Shankara Paneesha Igor Novitzky-Basso Aharon Gefen Neta Nevo Gernot Beutel Paul-Gerhardt Schlegel Thomas Klingebiel Peter Bader

Cells 2019 12 5;8(12). Epub 2019 Dec 5.

Department for Children and Adolescents, Division for Stem Cell Transplantation and Immunology, University Hospital Frankfurt, Frankfurt am Main, 60590 Frankfurt, Germany.

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December 2019

Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial.

Authors:
Michael Lübbert Olga Grishina Claudia Schmoor Richard F Schlenk Edgar Jost Martina Crysandt Michael Heuser Felicitas Thol Helmut R Salih Marcus M Schittenhelm Ulrich Germing Andrea Kuendgen Katharina S Götze Hans-Walter Lindemann Carsten Müller-Tidow Gerhard Heil Sebastian Scholl Gesine Bug Carsten Schwaenen Aristoteles Giagounidis Andreas Neubauer Jürgen Krauter Wolfram Brugger Maike De Wit Ralph Wäsch Heiko Becker Annette M May Justus Duyster Konstanze Döhner Arnold Ganser Björn Hackanson Hartmut Döhner

J Clin Oncol 2020 01 3;38(3):257-270. Epub 2019 Dec 3.

University Hospital of Ulm, Ulm, Germany.

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January 2020

HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1.

Authors:
Mandy Beyer Annette Romanski Al-Hassan M Mustafa Miriam Pons Iris Büchler Anja Vogel Andrea Pautz Andreas Sellmer Günter Schneider Gesine Bug Oliver H Krämer

Cancers (Basel) 2019 Sep 26;11(10). Epub 2019 Sep 26.

Department of Toxicology, University Medical Center, 55131 Mainz, Germany.

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September 2019

Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation.

Authors:
Christina A Ortmann Lena Dorsheimer Khalil Abou-El-Ardat Jennifer Hoffrichter Birgit Assmus Halvard Bonig Anica Scholz Heike Pfeifer Hans Martin Tobias Schmid Bernhard Brüne Sebastian Scheich Björn Steffen Julia Riemann Stella Hermann Alexandra Dukat Gesine Bug Christian H Brandts Sebastian Wagner Hubert Serve Michael A Rieger

Cell Rep 2019 05;27(7):2022-2028.e3

Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt am Main 60590, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. Electronic address:

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May 2019

Clearance of Hematologic Malignancies by Allogeneic Cytokine-Induced Killer Cell or Donor Lymphocyte Infusions.

Authors:
Michael Merker Emilia Salzmann-Manrique Verena Katzki Sabine Huenecke Melanie Bremm Shahrzad Bakhtiar Andre Willasch Andrea Jarisch Jan Soerensen Ansgar Schulz Roland Meisel Gesine Bug Halvard Bonig Thomas Klingebiel Peter Bader Eva Rettinger

Biol Blood Marrow Transplant 2019 07 13;25(7):1281-1292. Epub 2019 Mar 13.

Division of Stem Cell Transplantation and Immunology, Department of Children and Adolescents, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany. Electronic address:

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July 2019

Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.

Authors:
Jessica Barth Khalil Abou-El-Ardat Denis Dalic Nina Kurrle Anna-Maria Maier Sebastian Mohr Judith Schütte Lothar Vassen Gabriele Greve Johannes Schulz-Fincke Martin Schmitt Milica Tosic Eric Metzger Gesine Bug Cyrus Khandanpour Sebastian A Wagner Michael Lübbert Manfred Jung Hubert Serve Roland Schüle Tobias Berg

Leukemia 2019 Jun;33(6):1541

Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt/Main, Germany.

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June 2019

LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.

Authors:
Jessica Barth Khalil Abou-El-Ardat Denis Dalic Nina Kurrle Anna-Maria Maier Sebastian Mohr Judith Schütte Lothar Vassen Gabriele Greve Johannes Schulz-Fincke Martin Schmitt Milica Tosic Eric Metzger Gesine Bug Cyrus Khandanpour Sebastian A Wagner Michael Lübbert Manfred Jung Hubert Serve Roland Schüle Tobias Berg

Leukemia 2019 06 24;33(6):1411-1426. Epub 2019 Jan 24.

Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt/Main, Germany.

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June 2019

Biology-Driven Approaches to Prevent and Treat Relapse of Myeloid Neoplasia after Allogeneic Hematopoietic Stem Cell Transplantation.

Authors:
Robert Zeiser Dietrich W Beelen Wolfgang Bethge Martin Bornhäuser Gesine Bug Andreas Burchert Maximilian Christopeit Justus Duyster Jürgen Finke Armin Gerbitz Jan Henning Klusmann Guido Kobbe Michael Lübbert Carsten Müller-Tidow Uwe Platzbecker Wolf Rösler Martin Sauer Christoph Schmid Thomas Schroeder Mathias Stelljes Nicolaus Kröger Lutz P Müller

Biol Blood Marrow Transplant 2019 04 15;25(4):e128-e140. Epub 2019 Jan 15.

Department of Internal Medicine IV, Hematology and Oncology, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

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April 2019

Prophylactic donor lymphocyte infusion after allogeneic stem cell transplantation in acute leukaemia - a matched pair analysis by the Acute Leukaemia Working Party of EBMT.

Authors:
Christoph Schmid Myriam Labopin Nicolaas Schaap Hendrik Veelken Michael Schleuning Michael Stadler Juergen Finke Erin Hurst Frederic Baron Olle Ringden Gesine Bug Didier Blaise Johanna Tischer Adrian Bloor Jordi Esteve Sebastian Giebel Bipin Savani Norbert-Claude Gorin Fabio Ciceri Mohamad Mohty Arnon Nagler

Br J Haematol 2019 03 22;184(5):782-787. Epub 2018 Nov 22.

Chaim Sheba Medical Centre, Tel-Hashomer, Israel.

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March 2019

A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia.

Authors:
Hartmut Döhner Carsten Müller-Tidow Michael Lübbert Walter Fiedler Alwin Krämer Jörg Westermann Gesine Bug Richard F Schlenk Utz Krug Rainer-Georg Goeldner James Hilbert Tillmann Taube Oliver G Ottmann

Br J Haematol 2019 05 19;185(3):583-587. Epub 2018 Nov 19.

Department of Medicine, Haematology/Oncology, Goethe University, Frankfurt/Main, Germany.

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May 2019

Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial.

Authors:
Uwe Platzbecker Jan Moritz Middeke Katja Sockel Regina Herbst Dominik Wolf Claudia D Baldus Uta Oelschlägel Anke Mütherig Lars Fransecky Richard Noppeney Gesine Bug Katharina S Götze Alwin Krämer Tilmann Bochtler Matthias Stelljes Christoph Groth Antje Schubert Marika Mende Friedrich Stölzel Christine Borkmann Anne Sophie Kubasch Malte von Bonin Hubert Serve Mathias Hänel Ulrich Dührsen Johannes Schetelig Christoph Röllig Michael Kramer Gerhard Ehninger Martin Bornhäuser Christian Thiede

Lancet Oncol 2018 12 12;19(12):1668-1679. Epub 2018 Nov 12.

Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.

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December 2018

CMR imaging biosignature of cardiac involvement due to cancer-related treatment by T1 and T2 mapping.

Authors:
Jasmin D Haslbauer Sarah Lindner Silvia Valbuena-Lopez Hafisyatul Zainal Hui Zhou Tommaso D'Angelo Faraz Pathan Christophe A Arendt Gesine Bug Hubert Serve Thomas J Vogl Andreas M Zeiher Gerry Carr-White Eike Nagel Valentina O Puntmann

Int J Cardiol 2019 Jan 11;275:179-186. Epub 2018 Oct 11.

Institute of Experimental and Translational Cardiac Imaging, DZHK Centre for Cardiovascular Imaging, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Cardiology, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Cardiology, Guys and St Thomas' NHS Trust, London, United Kingdom. Electronic address:

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January 2019

Timepoints of vancomycin-resistant Enterococcus colonization predict outcomes of acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation.

Authors:
Sebastian Scheich Sarah Weber Rosalie König Anne C Wilke Sarah Lindner Claudia Reinheimer Thomas A Wichelhaus Michael Hogardt Volkhard A J Kempf Johanna Kessel Hans Martin Gesine Bug Hubert Serve Björn Steffen

Eur J Haematol 2018 Jul 26. Epub 2018 Jul 26.

Department of Hematology and Oncology, University Hospital Frankfurt, Frankfurt am Main, Germany.

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July 2018

Stenotrophomonas maltophilia colonization during allogeneic hematopoietic stem cell transplantation is associated with impaired survival.

Authors:
Sebastian Scheich Rosalie Koenig Anne C Wilke Sarah Lindner Claudia Reinheimer Thomas A Wichelhaus Michael Hogardt Volkhard A J Kempf Johanna Kessel Sarah Weber Hans Martin Gesine Bug Hubert Serve Björn Steffen

PLoS One 2018 19;13(7):e0201169. Epub 2018 Jul 19.

Department of Hematology and Oncology, Johann Wolfgang Goethe University of Frankfurt, Frankfurt am Main, Germany.

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January 2019

Phase I dose-escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia.

Authors:
Oliver G Ottmann Carsten Müller-Tidow Alwin Krämer Richard F Schlenk Michael Lübbert Gesine Bug Utz Krug Tilmann Bochtler Florian Voss Tillmann Taube Dan Liu Pilar Garin-Chesa Hartmut Döhner

Br J Haematol 2019 03 8;184(6):1018-1021. Epub 2018 Jun 8.

Department of Internal Medicine III, University of Ulm, Ulm, Germany.

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March 2019