Gert U Van Zyl

Gert U Van Zyl

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Gert U Van Zyl

Gert U Van Zyl

Publications by authors named "Gert U Van Zyl"

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Pharmacogenetics and pharmacokinetics of CNS penetration of efavirenz and its metabolites.

J Antimicrob Chemother 2019 03;74(3):699-709

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1093/jac/dky481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376850PMC
March 2019

Pooled PCR testing of dried blood spots for infant HIV diagnosis is cost efficient and accurate.

BMC Infect Dis 2019 Feb 11;19(1):136. Epub 2019 Feb 11.

The DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), Stellenbosch University, Stellenbosch, South Africa.

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3767-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371519PMC
February 2019

Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay.

Anal Biochem 2018 03 8;544:64-71. Epub 2017 Dec 8.

Department of Bioengineering, Rice University, 6100 Main St MS-142, Houston, TX 77005, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2017.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854266PMC
March 2018

Moderate levels of pre-therapy drug resistance (PDR) in a generalised epidemic: time for better first-line ART?

AIDS 2017 11 28;31(17):2387-2391. Epub 2017 Aug 28.

aSouth African Medical Research Council Collaborating Centre TygHIVLab, Division of Medical Virology, Stellenbosch University, South Africa bNational Health Laboratory Service, Tygerberg Business Unit, South Africa cANOVA Health Institute dDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000001629DOI Listing
November 2017

Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.

PLoS One 2013 26;8(6):e67188. Epub 2013 Jun 26.

National Health Laboratory Service, Tygerberg, Coastal Branch, South Africa ; Division of Medical Virology, Stellenbosch University, Faculty of Medicine and Health Sciences, Parow, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067188PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694021PMC
October 2017

Barriers to HIV remission research in low- and middle-income countries.

J Int AIDS Soc 2017 06;20(1):21521

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.7448/IAS.20.1.21521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515034PMC
June 2017

Is HIV-1C a risk factor for protease inhibitor failure?

Lancet HIV 2016 Apr 14;3(4):e149-51. Epub 2016 Mar 14.

Division of Clinical Pharmacology, Department Medicine, Stellenbosch University, Faculty of Medicine and Health Sciences, Parow, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S2352-3018(16)00040-0DOI Listing
April 2016

CD4 count-based failure criteria combined with viral load monitoring may trigger worse switch decisions than viral load monitoring alone.

Trop Med Int Health 2016 Feb 10;21(2):219-23. Epub 2015 Dec 10.

National Health Laboratory Service, Tygerberg, Cape Town, South Africa.

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http://dx.doi.org/10.1111/tmi.12639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717435PMC
February 2016

Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure.

J Clin Virol 2015 Jan 20;62:48-53. Epub 2014 Nov 20.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Francie van Zilj Drive, Parow 7500, South Africa; National Health Laboratory Service, Tygerberg, Francie van Zijl Drive, Parow 7500, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2014.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279108PMC
January 2015

Emerging antiretroviral drug resistance in sub-Saharan Africa: novel affordable technologies are needed to provide resistance testing for individual and public health benefits.

AIDS 2014 Nov;28(18):2643-8

aDivision of Medical Virology, Department of Pathology, Stellenbosch University and National Health Laboratory Service Tygerberg, Cape Town, South Africa bDepartments of Pediatrics, Laboratory Medicine and Global Health, University of Washington, and Seattle Children's Research Institute cDepartments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, Washington, USA dDepartment of Medicine and Center for Infectious Diseases, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa eDepartments of International Health and Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland fDivision of Infectious Diseases, Department of Medicine gDepartment of Epidemiology, Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784963PMC
November 2014

Irreproducible positive results on the Cobas AmpliPrep/Cobas TaqMan HIV-1 Qual test are different qualitatively from confirmed positive results.

J Med Virol 2014 Jan 17;86(1):82-7. Epub 2013 Oct 17.

Division of Medical Virology, Department of Pathology, Stellenbosch University Faculty of Medicine and Health Sciences and National Health Laboratory Service, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jmv.23811DOI Listing
January 2014

Establishing diagnostic cut-off criteria for the COBAS AmpliPrep/COBAS TaqMan HIV-1 Qualitative test through validation against the Amplicor DNA test v1.5 for infant diagnosis using dried blood spots.

J Clin Virol 2012 Feb 21;53(2):106-9. Epub 2011 Dec 21.

Division of Medical Virology, Department of Pathology, Faculty of Health Sciences, Stellenbosch University and National Health Laboratory Service Tygerberg, P.O. Box 19063, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1016/j.jcv.2011.12.002DOI Listing
February 2012

It is time to consider third-line options in antiretroviral-experienced paediatric patients?

J Int AIDS Soc 2011 Nov 15;14:55. Epub 2011 Nov 15.

Division of Medical Virology, Stellenbosch University, and National Health Laboratory Service Tygerberg, Parow, Cape Town, South Africa.

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http://dx.doi.org/10.1186/1758-2652-14-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228719PMC
November 2011

Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the Western Cape, South Africa.

J Med Virol 2011 Oct;83(10):1764-9

Division of Medical Virology, Stellenbosch University, Tygerberg, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jmv.22189DOI Listing
October 2011

HIV treatment adherence, drug resistance, virologic failure: evolving concepts.

Infect Disord Drug Targets 2011 Apr;11(2):167-74

Departments of International Health and Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072419PMC
http://dx.doi.org/10.2174/187152611795589663DOI Listing
April 2011

Young age a predictor of weak reactivity in a rapid antibody test in infants infected with HIV.

J Med Virol 2010 Aug;82(8):1314-7

Division of Medical Virology, Department of Pathology, National Health Laboratory Service, University of Stellenbosch, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jmv.21832DOI Listing
August 2010

Surveillance of transmitted resistance to antiretroviral drug classes among young children in the Western Cape Province of South Africa.

Pediatr Infect Dis J 2010 Apr;29(4):370-1

Division of Medical Virology, Stellenbosch University, Tygerberg, South Africa.

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http://dx.doi.org/10.1097/INF.0b013e3181c4dadaDOI Listing
April 2010

Protease inhibitor resistance in South African children with virologic failure.

Pediatr Infect Dis J 2009 Dec;28(12):1125-7

Centre for Infectious Diseases, Division of Medical Virology, Tygerberg and Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1097/INF.0b013e3181af829dDOI Listing
December 2009