Gert Jan Lammers

Gert Jan Lammers

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Gert Jan Lammers

Publications by authors named "Gert Jan Lammers"

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Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.

Nat Rev Neurol 2019 Sep 19;15(9):519-539. Epub 2019 Jul 19.

Sleep-Wake Disorders Center, Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, University of Montpellier, Montpellier, France.

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http://dx.doi.org/10.1038/s41582-019-0226-9DOI Listing
September 2019

Striking cessation of cataplexy by opioids.

J Sleep Res 2019 Aug 12;28(4):e12781. Epub 2018 Oct 12.

Neuropsychiatric Institute and Brain Research Institute, University of California, Los Angeles, Los Angeles.

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http://dx.doi.org/10.1111/jsr.12781DOI Listing
August 2019

Widespread white matter connectivity abnormalities in narcolepsy type 1: A diffusion tensor imaging study.

Neuroimage Clin 2019 Jul 29;24:101963. Epub 2019 Jul 29.

Department of Anatomy and Neurosciences, Amsterdam UMC (Location VUmc), Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.nicl.2019.101963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698319PMC
July 2019

Decreased body mass index during treatment with sodium oxybate in narcolepsy type 1.

J Sleep Res 2019 Jun 4;28(3):e12684. Epub 2018 Mar 4.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jsr.12684DOI Listing
June 2019

Publisher Correction: Enhanced food-related responses in the ventral medial prefrontal cortex in narcolepsy type 1.

Sci Rep 2019 Jun 14;9(1):8766. Epub 2019 Jun 14.

Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-44073-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572814PMC
June 2019

Coexisting narcolepsy (with and without cataplexy) and multiple sclerosis : Six new cases and a literature review.

J Neurol 2018 Sep 4;265(9):2071-2078. Epub 2018 Jul 4.

Leiden Medical University Center and University of Leiden, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00415-018-8949-xDOI Listing
September 2018

Drugs Used in Narcolepsy and Other Hypersomnias.

Authors:
Gert Jan Lammers

Sleep Med Clin 2018 Jun;13(2):183-189

Department of Neurology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 AA, The Netherlands; Sleep-Wake Centers of SEIN, Achterweg 5, 2103 SW Heemstede, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jsmc.2018.02.009DOI Listing
June 2018

Eating Decisions Based on Alertness Levels After a Single Night of Sleep Manipulation: A Randomized Clinical Trial.

Sleep 2017 Feb;40(2)

Department of Psychiatry and Behavioral Sciences, Stanford University. Stanford, CA.

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http://dx.doi.org/10.1093/sleep/zsw039DOI Listing
February 2017

Sleep in 2016: methodological issues and progress.

Authors:
Gert Jan Lammers

Lancet Neurol 2017 Jan;16(1):15-17

Leiden University Medical Centre, Leiden, Netherlands; Sleep Wake Centers SEIN, Heemstede, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)30337-4DOI Listing
January 2017

Aberrant Food Choices after Satiation in Human Orexin-Deficient Narcolepsy Type 1.

Sleep 2016 Nov 1;39(11):1951-1959. Epub 2016 Nov 1.

Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.

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http://dx.doi.org/10.5665/sleep.6222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070749PMC
November 2016

Improved vigilance after sodium oxybate treatment in narcolepsy: a comparison between in-field and in-laboratory measurements.

J Sleep Res 2016 08 23;25(4):486-96. Epub 2016 Feb 23.

Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jsr.12386DOI Listing
August 2016

Pandemic influenza vaccine & narcolepsy: simulations on the potential impact of bias.

Expert Rev Vaccines 2016 May 31;15(5):573-84. Epub 2016 Mar 31.

a Department of Medical Informatics Erasmus MC Rotterdam , The Netherlands.

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http://dx.doi.org/10.1586/14760584.2016.1164045DOI Listing
May 2016

Bringing posttraumatic sleep-wake disorders out of the dark.

Neurology 2016 05 27;86(21):1934-5. Epub 2016 Apr 27.

From the Department of Neurology (B.L.E.), Massachusetts General Hospital, Boston; Athinoula A. Martinos Center for Biomedical Imaging (B.L.E.), Massachusetts General Hospital, Charlestown, MA; Department of Neurology and Clinical Neurophysiology (G.J.L.), Leiden University Medical Center; and SleepWake Center SEIN (G.J.L.), Heemstede, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000002710DOI Listing
May 2016

Pearls & Oy-sters: Diagnostic challenges in nocturnal frontal lobe epilepsy.

Neurology 2016 Apr;86(14):e151-e153

From Stichting Epilepsie Instellingen Nederland (SEIN) (F.M.E.C., G.J.L., R.D.T., G.H.V.), Heemstede; and Leiden University Medical Center (G.J.L., R.D.T.), the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000002539DOI Listing
April 2016

Time- and state-dependent analysis of autonomic control in narcolepsy: higher heart rate with normal heart rate variability independent of sleep fragmentation.

J Sleep Res 2015 Apr 9;24(2):206-14. Epub 2014 Nov 9.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands; Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/jsr.12253DOI Listing
April 2015

[Putting sleep disorders in context].

Ned Tijdschr Geneeskd 2015 ;159:A8799

* Namens de Nederlandse Vereniging voor Slaap Waak Onderzoek (NSWO), de werkgroep Slaap- en Waakstoornissen van de Nederlandse Vereniging voor Neurologie en de Federatie van algemene Slaap Centra (FSC).

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April 2015

The MSLT: More objections than benefits as a diagnostic gold standard?

Sleep 2014 Jun 1;37(6):1027-8. Epub 2014 Jun 1.

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Center, Leiden, The Netherlands ; Sleep Wake Center SEIN, Heemstede, The Netherlands.

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http://dx.doi.org/10.5665/sleep.3748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015373PMC
June 2014

Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study.

Sleep 2014 Apr 1;37(4):795-801. Epub 2014 Apr 1.

Department of Neurology Leiden University Medical Centre, Leiden, The Netherlands ; Sleep Wake Center SEIN, Heemstede, The Netherlands.

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http://dx.doi.org/10.5665/sleep.3592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044740PMC
April 2014

Impaired sustained attention in adult patients with type 1 diabetes is related to diabetes per se.

Diabetes Metab Res Rev 2014 Feb;30(2):132-9

Departments of Endocrinology and Metabolic Diseases (MvD, ED, EPMC, JAR), Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/dmrr.2467DOI Listing
February 2014

Delusional confusion of dreaming and reality in narcolepsy.

Sleep 2014 Feb 1;37(2):419-22. Epub 2014 Feb 1.

Department of Psychiatry, Harvard Medical School, Boston, MA ; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.5665/sleep.3428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900627PMC
February 2014

Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial.

Lancet Neurol 2013 Nov 7;12(11):1068-75. Epub 2013 Oct 7.

Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, University of Montpellier 1, Montpellier, France.

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http://dx.doi.org/10.1016/S1474-4422(13)70225-4DOI Listing
November 2013

Association between hypocretin-1 and amyloid-β42 cerebrospinal fluid levels in Alzheimer's disease and healthy controls.

Curr Alzheimer Res 2012 Dec;9(10):1119-25

Department of Geriatric Medicine, Radboud University Nijmegen Medical Centre, 925, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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December 2012

Restless legs syndrome.

BMJ 2012 Nov 20;345:e7592. Epub 2012 Nov 20.

Stichting Restless Legs, Beysterveld 27, 1083 KA Amsterdam, Netherlands.

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http://dx.doi.org/10.1136/bmj.e7592DOI Listing
November 2012

Hypocretin (orexin) loss in Alzheimer's disease.

Neurobiol Aging 2012 Aug 5;33(8):1642-50. Epub 2011 May 5.

Netherlands Institute for Neurosciences, an Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2011.03.014DOI Listing
August 2012

Sustained attention to response task (SART) shows impaired vigilance in a spectrum of disorders of excessive daytime sleepiness.

J Sleep Res 2012 Aug 19;21(4):390-5. Epub 2011 Nov 19.

Leiden University Medical Centre, Department of Neurology and Clinical Neurophysiology, Leiden, The Netherlands.

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http://doi.wiley.com/10.1111/j.1365-2869.2011.00979.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2869.2011.00979.xDOI Listing
August 2012

Severe fatigue in narcolepsy with cataplexy.

J Sleep Res 2012 Apr 16;21(2):163-9. Epub 2011 Aug 16.

Department of Psychiatry, Radboud University Nijmegen Medical Center, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2869.2011.00943.xDOI Listing
April 2012

Altered circadian rhythm of melatonin concentrations in hypocretin-deficient men.

Chronobiol Int 2012 Apr;29(3):356-62

Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.3109/07420528.2012.655869DOI Listing
April 2012

Month of birth is not a risk factor for narcolepsy with cataplexy in the Netherlands.

J Sleep Res 2011 Dec 16;20(4):522-5. Epub 2011 Jun 16.

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2869.2011.00933.xDOI Listing
December 2011

Intranasal hypocretin-1: making sense of scents?

Authors:
Gert Jan Lammers

Sleep Med 2011 Dec;12(10):939-40

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http://dx.doi.org/10.1016/j.sleep.2011.11.002DOI Listing
December 2011

Effect of sodium oxybate on growth hormone secretion in narcolepsy patients and healthy controls.

Am J Physiol Endocrinol Metab 2011 Jun 29;300(6):E1069-75. Epub 2011 Mar 29.

Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00623.2010DOI Listing
June 2011

Reward-seeking behavior in human narcolepsy.

J Clin Sleep Med 2011 Jun;7(3):293-300

Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.5664/JCSM.1076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113969PMC
June 2011

Sodium oxybate increases prolactin secretion in narcolepsy patients and healthy controls.

Eur J Endocrinol 2011 Mar 10;164(3):363-70. Epub 2010 Dec 10.

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Postal Zone J3-R 151, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1530/EJE-10-0913DOI Listing
March 2011

The clinical features of cataplexy: a questionnaire study in narcolepsy patients with and without hypocretin-1 deficiency.

Sleep Med 2011 Jan 8;12(1):12-8. Epub 2010 Dec 8.

Department of Neurology, Donders Institute for Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S138994571000301
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http://dx.doi.org/10.1016/j.sleep.2010.05.010DOI Listing
January 2011

Sleep and circadian rhythm alterations correlate with depression and cognitive impairment in Huntington's disease.

Parkinsonism Relat Disord 2010 Jun 16;16(5):345-50. Epub 2010 Mar 16.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.parkreldis.2010.02.009DOI Listing
June 2010

A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects.

J Clin Endocrinol Metab 2010 Jun 6;95(6):2963-8. Epub 2010 Apr 6.

Department of Endocrinology and Metabolic Diseases, C4-R, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
Publisher Site
http://dx.doi.org/10.1210/jc.2009-2430DOI Listing
June 2010

CSF hypocretin-1 levels are normal in patients with amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2009 Oct-Dec;10(5-6):487-9

Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Department of Neurology, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3109/17482960802315024DOI Listing
February 2010

[Sleep disorders and the ability to drive, revision of legislation].

Ned Tijdschr Geneeskd 2009 ;153:A690

Nederlands Kenniscentrum Arbeid en Longaandoeningen, Utrecht, The Netherlands.

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February 2010

Psychotic symptoms in narcolepsy: phenomenology and a comparison with schizophrenia.

Gen Hosp Psychiatry 2009 Mar-Apr;31(2):146-54. Epub 2009 Jan 24.

Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.genhosppsych.2008.12.002DOI Listing
August 2009

Hypocretin/orexin disturbances in neurological disorders.

Sleep Med Rev 2009 Feb 25;13(1):9-22. Epub 2008 Sep 25.

Netherlands Institute for Neuroscience, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.smrv.2008.05.002DOI Listing
February 2009

Hypocretin and melanin-concentrating hormone in patients with Huntington disease.

Brain Pathol 2008 Oct 22;18(4):474-83. Epub 2008 May 22.

Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/j.1750-3639.2008.00135.xDOI Listing
October 2008

Increased heart rate variability but normal resting metabolic rate in hypocretin/orexin-deficient human narcolepsy.

J Clin Sleep Med 2008 Jun;4(3):248-54

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://www.aasmnet.org/JCSM/Articles/040309.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546458PMC
June 2008

Narcolepsy: immunological aspects.

Sleep Med Rev 2008 Apr 4;12(2):95-107. Epub 2008 Mar 4.

Department of Neurology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.smrv.2007.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366136PMC
April 2008

Hypocretin (orexin) loss in Parkinson's disease.

Brain 2007 Jun 30;130(Pt 6):1577-85. Epub 2007 Apr 30.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/brain/awm090DOI Listing
June 2007

Altered skin-temperature regulation in narcolepsy relates to sleep propensity.

Sleep 2006 Nov;29(11):1444-9

Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/sleep/29.11.1444DOI Listing
November 2006

Possible confusion between primary hypersomnia and adult attention-deficit/hyperactivity disorder.

Psychiatry Res 2006 Aug 18;143(2-3):293-7. Epub 2006 Jul 18.

Department of Neurology, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.psychres.2006.02.009DOI Listing
August 2006

Cataplexy leading to the diagnosis of Niemann-Pick disease type C.

Pediatr Neurol 2006 Jul;35(1):82-4

Department of Pediatric Neurology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.pediatrneurol.2005.12.012DOI Listing
July 2006

Focusing on vigilance instead of sleepiness in the assessment of narcolepsy: high sensitivity of the Sustained Attention to Response Task (SART).

Sleep 2006 Feb;29(2):187-91

Leiden University Medical Centre, Department of Neurology and Clinical Neurophysiology, The Netherlands.

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February 2006

The number of hypothalamic hypocretin (orexin) neurons is not affected in Prader-Willi syndrome.

J Clin Endocrinol Metab 2005 Sep 28;90(9):5466-70. Epub 2005 Jun 28.

Netherlands Institute for Brain Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2005-0296DOI Listing
September 2005

Altered setting of the pituitary-thyroid ensemble in hypocretin-deficient narcoleptic men.

Am J Physiol Endocrinol Metab 2005 May 29;288(5):E892-9. Epub 2004 Dec 29.

Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00327.2004DOI Listing
May 2005

Hypernatremia from a hunger strike as a cause of osmotic myelinolysis.

Neurology 2005 Feb;64(3):574-5

Department of Intensive Care, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1212/01.WNL.0000150730.80325.11DOI Listing
February 2005

Corticospinal excitability during laughter: implications for cataplexy and the comparison with REM sleep atonia.

J Sleep Res 2004 Sep;13(3):257-64

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2869.2004.00411.xDOI Listing
September 2004

Is motor inhibition during laughter due to emotional or respiratory influences?

Psychophysiology 2004 Mar;41(2):254-8

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/j.1469-8986.2003.00145.xDOI Listing
March 2004

Assessment of sleep and sleepiness in Parkinson disease.

Sleep 2003 Dec;26(8):1049-54

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/sleep/26.8.1049DOI Listing
December 2003

Pharmacological management of narcolepsy.

Expert Opin Pharmacother 2003 Oct;4(10):1739-46

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1517/14656566.4.10.1739DOI Listing
October 2003

Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity.

Obes Res 2003 Sep;11(9):1147-54

Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/oby.2003.156DOI Listing
September 2003

Screening for anti-ganglioside antibodies in hypocretin-deficient human narcolepsy.

Neurosci Lett 2003 Apr;341(1):13-6

Department of Neurology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/s0304-3940(03)00085-5DOI Listing
April 2003

Somatotropic axis in hypocretin-deficient narcoleptic humans: altered circadian distribution of GH-secretory events.

Am J Physiol Endocrinol Metab 2003 Mar 26;284(3):E641-7. Epub 2002 Nov 26.

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00421.2002DOI Listing
March 2003

Voxel-based morphometry in hypocretin-deficient narcolepsy.

Sleep 2003 Feb;26(1):44-6

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Center, Leiden, The Netherlands.

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February 2003

Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy.

Curr Opin Neurol 2002 Dec;15(6):739-45

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/01.wco.0000044800.53746.5aDOI Listing
December 2002

Anti-Ri antibody positive opsoclonus-myoclonus in a male patient with breast carcinoma.

J Neurol 2002 Dec;249(12):1710-2

Department of Neurology, J3R-166, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00415-002-0913-zDOI Listing
December 2002

Cataplexy: 'tonic immobility' rather than 'REM-sleep atonia'?

Sleep Med 2002 Nov;3(6):471-7

Department of Neurology & Clinical Neurophysiology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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November 2002