Publications by authors named "Gerry Melino"

100Publications

Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?

Biol Direct 2020 Nov 27;15(1):28. Epub 2020 Nov 27.

CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China.

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http://dx.doi.org/10.1186/s13062-020-00282-3DOI Listing
November 2020

IGF2R-initiated proton rechanneling dictates an anti-inflammatory property in macrophages.

Sci Adv 2020 Nov 25;6(48). Epub 2020 Nov 25.

CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1126/sciadv.abb7389DOI Listing
November 2020

Commensal microbes and p53 in cancer progression.

Biol Direct 2020 Nov 19;15(1):25. Epub 2020 Nov 19.

Department of Experimental Medicine, TOR, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1186/s13062-020-00281-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678320PMC
November 2020

Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and autophagy.

Free Radic Biol Med 2020 Oct 24. Epub 2020 Oct 24.

The First Affiliated Hospital of Soochow University, State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Soochow University Medical College, Suzhou, Jiangsu, 215123, China. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2020.10.029DOI Listing
October 2020

Cancer predictive studies.

Biol Direct 2020 Oct 14;15(1):18. Epub 2020 Oct 14.

Torvergata Oncoscience Research Centre of Excellence, TOR, Department of Experimental Medicine, University of Rome Tor Vergata, via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1186/s13062-020-00274-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557058PMC
October 2020

Activating Effect of 3-Benzylidene Oxindoles on AMPK: From Computer Simulation to High-Content Screening.

ChemMedChem 2020 Aug 6. Epub 2020 Aug 6.

Laboratory of Molecular Pharmacology, Saint Petersburg State Institute of Technology (Technical University), Moskovskii pr. 26, 190013, Saint Petersburg, Russia.

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http://dx.doi.org/10.1002/cmdc.202000579DOI Listing
August 2020

Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.

Cell Death Differ 2020 Jul 21. Epub 2020 Jul 21.

Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1038/s41418-020-0590-4DOI Listing
July 2020

Regulation of Adult Neurogenesis in Mammalian Brain.

Int J Mol Sci 2020 Jul 9;21(14). Epub 2020 Jul 9.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms21144869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402357PMC
July 2020

Is hydroxychloroquine beneficial for COVID-19 patients?

Cell Death Dis 2020 07 8;11(7):512. Epub 2020 Jul 8.

Department of Rheumatology and Immunology, The Third Affiliated Hospital of Southern Medical University, No. 183, Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong, China.

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http://dx.doi.org/10.1038/s41419-020-2721-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341710PMC
July 2020

P73 C-terminus is dispensable for multiciliogenesis.

Cell Cycle 2020 Jul 25;19(14):1833-1845. Epub 2020 Jun 25.

Medical Research Council, Toxicology Unit, Department of Pathology, Cambridge University , Cambridge, UK.

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http://dx.doi.org/10.1080/15384101.2020.1783055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469635PMC
July 2020

The C terminus of p73 is essential for hippocampal development.

Proc Natl Acad Sci U S A 2020 07 22;117(27):15694-15701. Epub 2020 Jun 22.

Department of Experimental Medicine, TOR Center, University of Rome Tor Vergata, 00133 Rome, Italy;

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http://dx.doi.org/10.1073/pnas.2000917117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355003PMC
July 2020

The Impact of the Ubiquitin System in the Pathogenesis of Squamous Cell Carcinomas.

Cancers (Basel) 2020 Jun 16;12(6). Epub 2020 Jun 16.

National Research Council of Italy, Institute of Translational Pharmacology, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/cancers12061595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352818PMC
June 2020

Mesenchymal stromal cells pretreated with pro-inflammatory cytokines promote skin wound healing through VEGFC-mediated angiogenesis.

Stem Cells Transl Med 2020 Jun 13. Epub 2020 Jun 13.

The First Affiliated Hospital of Soochow University, State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Soochow University Medical College, Suzhou, People's Republic of China.

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http://dx.doi.org/10.1002/sctm.19-0241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519767PMC
June 2020

COVID-19 infection: the China and Italy perspectives.

Cell Death Dis 2020 06 8;11(6):438. Epub 2020 Jun 8.

Shanghai Public Health Clinical Center, Shanghai, 201508, China.

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http://dx.doi.org/10.1038/s41419-020-2603-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278221PMC
June 2020

HSD11B1 is upregulated synergistically by IFNγ and TNFα and mediates TSG-6 expression in human UC-MSCs.

Cell Death Discov 2020 20;6:24. Epub 2020 Apr 20.

1State Key Laboratory of Radiation Medicine and Protection, Institute for Translational Medicine, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Medical College of Soochow University, Suzhou, China.

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http://dx.doi.org/10.1038/s41420-020-0262-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168568PMC
April 2020

ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes.

Oncogene 2020 05 20;39(22):4331-4343. Epub 2020 Apr 20.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41388-020-1277-5DOI Listing
May 2020

Context is everything: extrinsic signalling and gain-of-function p53 mutants.

Cell Death Discov 2020 23;6:16. Epub 2020 Mar 23.

1Department of Experimental Medicine, TOR, University of Rome ''Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.1038/s41420-020-0251-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090043PMC
March 2020

COVID-19 infection: the perspectives on immune responses.

Cell Death Differ 2020 05 23;27(5):1451-1454. Epub 2020 Mar 23.

Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-020-0530-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091918PMC
May 2020

The role of noncoding RNAs in epithelial cancer.

Cell Death Discov 2020 12;6:13. Epub 2020 Mar 12.

1Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.1038/s41420-020-0247-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067833PMC
March 2020

Skeletal muscle stem cells confer maturing macrophages anti-inflammatory properties through insulin-like growth factor-2.

Stem Cells Transl Med 2020 07 16;9(7):773-785. Epub 2020 Mar 16.

The First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Medical College of Soochow University, Suzhou, People's Republic of China.

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http://dx.doi.org/10.1002/sctm.19-0447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308640PMC
July 2020

Transglutaminase 3 Reduces the Severity of Psoriasis in Imiquimod-Treated Mouse Skin.

Int J Mol Sci 2020 Feb 25;21(5). Epub 2020 Feb 25.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms21051566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084269PMC
February 2020

Scd1 controls de novo beige fat biogenesis through succinate-dependent regulation of mitochondrial complex II.

Proc Natl Acad Sci U S A 2020 02 17;117(5):2462-2472. Epub 2020 Jan 17.

CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

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http://dx.doi.org/10.1073/pnas.1914553117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007576PMC
February 2020

Do Mutations Turn p53 into an Oncogene?

Int J Mol Sci 2019 Dec 11;20(24). Epub 2019 Dec 11.

Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms20246241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940991PMC
December 2019

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms.

Cancers (Basel) 2019 Dec 9;11(12). Epub 2019 Dec 9.

Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133 Roma, Italy.

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http://dx.doi.org/10.3390/cancers11121983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966539PMC
December 2019

p63 Is a Promising Marker in the Diagnosis of Unusual Skin Cancer.

Int J Mol Sci 2019 Nov 17;20(22). Epub 2019 Nov 17.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms20225781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888618PMC
November 2019

Biomarkers for vascular ageing in aorta tissues and blood samples.

Exp Gerontol 2019 12 21;128:110741. Epub 2019 Oct 21.

Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Palermo, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2019.110741DOI Listing
December 2019

Transglutaminase 3 is expressed in basal cell carcinoma of the skin.

Eur J Dermatol 2019 Oct;29(5):477-483

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133 Rome, Italy, Istituto Dermopatico dell'Immacolata-IRCCS, 00163 Rome, Italy.

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http://dx.doi.org/10.1684/ejd.2019.3636DOI Listing
October 2019

Stearoyl CoA Desaturase Regulates Ferroptosis in Ovarian Cancer Offering New Therapeutic Perspectives.

Cancer Res 2019 Oct;79(20):5149-5150

Department of Experimental Medicine, TOR, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2453DOI Listing
October 2019

HECT-Type E3 Ubiquitin Ligases in Cancer.

Trends Biochem Sci 2019 12 11;44(12):1057-1075. Epub 2019 Oct 11.

Department of Experimental Medicine, TOR, University of Rome 'Tor Vergata', Rome 00133, Italy; Medical Research Council Toxicology Unit, Department of Pathology, Cambridge University, Cambridge CB2 1QP, UK.

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http://dx.doi.org/10.1016/j.tibs.2019.08.004DOI Listing
December 2019

ZNF281 is recruited on DNA breaks to facilitate DNA repair by non-homologous end joining.

Oncogene 2020 01 30;39(4):754-766. Epub 2019 Sep 30.

Medical Research Council, Toxicology Unit, University of Cambridge, Leicester, LE1 9HN, UK.

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http://dx.doi.org/10.1038/s41388-019-1028-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976523PMC
January 2020

Lipid metabolism offers anticancer treatment by regulating ferroptosis.

Cell Death Differ 2019 12 23;26(12):2516-2519. Epub 2019 Sep 23.

Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-019-0418-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224363PMC
December 2019

Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation.

Mol Oncol 2019 10 5;13(10):2033-2048. Epub 2019 Sep 5.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Italy.

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http://dx.doi.org/10.1002/1878-0261.12567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763782PMC
October 2019

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.

Cell Death Differ 2020 04 21;27(4):1155-1168. Epub 2019 Aug 21.

Department of Biology, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-019-0404-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206129PMC
April 2020

Developmental programming of adult haematopoiesis system.

Ageing Res Rev 2019 09 19;54:100918. Epub 2019 Jun 19.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Rome, Italy; MRC-Toxicology Unit, University of Cambridge, UK.

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http://dx.doi.org/10.1016/j.arr.2019.100918DOI Listing
September 2019

p63 at the Crossroads between Stemness and Metastasis in Breast Cancer.

Int J Mol Sci 2019 May 31;20(11). Epub 2019 May 31.

National Research Council of Italy, Institute of Translational Pharmacology, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms20112683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600246PMC
May 2019

Smyd2 conformational changes in response to p53 binding: role of the C-terminal domain.

Mol Oncol 2019 06 21;13(6):1450-1461. Epub 2019 May 21.

Department for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), University of Tuscia, Viterbo, Italy.

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http://dx.doi.org/10.1002/1878-0261.12502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547616PMC
June 2019

Single cell transcriptomic analysis of human mesenchymal stem cells reveals limited heterogeneity.

Cell Death Dis 2019 05 8;10(5):368. Epub 2019 May 8.

CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.

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http://www.nature.com/articles/s41419-019-1583-4
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http://dx.doi.org/10.1038/s41419-019-1583-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506509PMC
May 2019

Cell death pathologies: targeting death pathways and the immune system for cancer therapy.

Genes Immun 2019 09 19;20(7):539-554. Epub 2018 Dec 19.

Medical Research Council, Toxicology Unit, University of Cambridge, Hodgkin Building, Lancaster Road, P.O. Box 138, Leicester, LE1 9HN, UK.

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http://www.nature.com/articles/s41435-018-0052-x
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http://dx.doi.org/10.1038/s41435-018-0052-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451632PMC
September 2019

TAp73 regulates ATP7A: possible implications for ageing-related diseases.

Aging (Albany NY) 2018 12;10(12):3745-3760

MRC Toxicology Unit, University of Cambridge, Leicester LE1 7HB, United Kingdom.

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http://dx.doi.org/10.18632/aging.101669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326685PMC
December 2018

Myoblasts rely on TAp63 to control basal mitochondria respiration.

Aging (Albany NY) 2018 11;10(11):3558-3573

Department of Experimental Medicine and TOR, University of Rome "Tor Vergata", Rome, Italy.

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http://www.aging-us.com/article/101668/text
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http://dx.doi.org/10.18632/aging.101668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286837PMC
November 2018

Orphan receptor NR4A3 is a novel target of p53 that contributes to apoptosis.

Oncogene 2019 03 19;38(12):2108-2122. Epub 2018 Nov 19.

Gene Expression Program, Institute of Cytology, Saint-Petersburg, Russia, 194064.

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http://www.nature.com/articles/s41388-018-0566-8
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http://dx.doi.org/10.1038/s41388-018-0566-8DOI Listing
March 2019

Cell death in cancer in the era of precision medicine.

Genes Immun 2019 09 19;20(7):529-538. Epub 2018 Oct 19.

Department of Experimental Medicine TOR, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.

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http://www.nature.com/articles/s41435-018-0048-6
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http://dx.doi.org/10.1038/s41435-018-0048-6DOI Listing
September 2019

ΔNp63 regulates the expression of hyaluronic acid-related genes in breast cancer cells.

Oncogenesis 2018 Aug 24;7(8):65. Epub 2018 Aug 24.

National Research Council of Italy, (CNR), Institute of Translational Pharmacology (IFT), Via Fosso del Cavaliere 100, Rome, 00133, Italy.

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http://dx.doi.org/10.1038/s41389-018-0073-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107578PMC
August 2018

Similar Domains for Different Regulations of p53 Family.

Structure 2018 08;26(8):1047-1049

MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK; Department of Experimental Medicine & Surgery, University of Rome Tor Vergata, Rome 00133, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.07.003DOI Listing
August 2018

ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma.

Proc Natl Acad Sci U S A 2018 07 25;115(28):7356-7361. Epub 2018 Jun 25.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", 00133 Rome, Italy;

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http://dx.doi.org/10.1073/pnas.1801435115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048510PMC
July 2018

TAp73 contributes to the oxidative stress response by regulating protein synthesis.

Proc Natl Acad Sci U S A 2018 06 29;115(24):6219-6224. Epub 2018 May 29.

Medical Research Council, Toxicology Unit, University of Cambridge, Leicester LE1 9HN, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1718531115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004440PMC
June 2018

p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms.

J Mol Biol 2018 06 4;430(13):1829-1838. Epub 2018 May 4.

MRC Toxicology Unit, University of Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995411PMC
June 2018

Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation.

Cell Death Dis 2018 05 1;9(5):504. Epub 2018 May 1.

University of Manchester, Faculty of Medical and Human Sciences, Division of Cancer Sciences, Manchester Cancer Research Centre, Wilmslow Road, Manchester, M20 4QL, UK.

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http://dx.doi.org/10.1038/s41419-018-0521-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938710PMC
May 2018

Order must spring from chaos in Italian research.

Authors:
Gerry Melino

Nature 2018 04;556(7702):436

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http://dx.doi.org/10.1038/d41586-018-04896-6DOI Listing
April 2018

Kruppel-like factor 4 regulates keratinocyte senescence.

Biochem Biophys Res Commun 2018 05 26;499(2):389-395. Epub 2018 Mar 26.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", via Montpellier, 1, 00133, Rome, Italy; Istituto Dermopatico dell'Immacolata, IRCCS, via Monti di Creta 104, 00163, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.03.172DOI Listing
May 2018

Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2.

Cell Death Dis 2018 02 15;9(3):257. Epub 2018 Feb 15.

National Institute for Infectious Diseases, IRCCS "Lazzaro Spallanzani", Rome, Italy.

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http://dx.doi.org/10.1038/s41419-018-0292-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833377PMC
February 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

The hypoxic tumour microenvironment.

Oncogenesis 2018 Jan 24;7(1):10. Epub 2018 Jan 24.

Medical Research Council, Toxicology Unit, Leicester University, Hodgkin Building, Lancaster Road, P.O. Box 138, Leicester, LE1 9HN, UK.

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http://dx.doi.org/10.1038/s41389-017-0011-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833859PMC
January 2018

Integrin-β4 is a novel transcriptional target of TAp73.

Cell Cycle 2018 8;17(5):589-594. Epub 2018 Feb 8.

a MRC Toxicology Unit , Hodgkin Building , Lancaster Road, Leicester LE1 9HN , United Kingdom.

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http://dx.doi.org/10.1080/15384101.2017.1403684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969564PMC
September 2019

Tissue regeneration: The crosstalk between mesenchymal stem cells and immune response.

Cell Immunol 2018 04 2;326:86-93. Epub 2017 Dec 2.

University of Rome 'Tor Vergata', Department of Experimental Medicine and Surgery, Building D, Room D26, II Floor, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.cellimm.2017.11.010DOI Listing
April 2018

ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis.

Proc Natl Acad Sci U S A 2017 12 21;114(50):13254-13259. Epub 2017 Nov 21.

Institute of Cell Biology and Neurobiology, National Research Council of Italy (CNR), 00015 Monterotondo (Rome), Italy;

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http://dx.doi.org/10.1073/pnas.1711777114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740608PMC
December 2017

Zinc-finger proteins in health and disease.

Cell Death Discov 2017 13;3:17071. Epub 2017 Nov 13.

ENEA Research Center Casaccia, Laboratory of Biosafety and Risk Assessment, Via Anguillarese, Rome, Italy.

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http://dx.doi.org/10.1038/cddiscovery.2017.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683310PMC
November 2017

Proapoptotic modification of substituted isoindolinones as MDM2-p53 inhibitors.

Bioorg Med Chem Lett 2017 12 20;27(23):5197-5202. Epub 2017 Oct 20.

St. Petersburg State Institute of Technology (Technical University), St. Petersburg 190013, Russia.

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http://dx.doi.org/10.1016/j.bmcl.2017.10.049DOI Listing
December 2017

Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism.

Cell Death Differ 2018 01 27;25(1):144-153. Epub 2017 Oct 27.

Department of Pathology, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1038/cdd.2017.178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729534PMC
January 2018

TAp73 is a marker of glutamine addiction in medulloblastoma.

Genes Dev 2017 09 26;31(17):1738-1753. Epub 2017 Sep 26.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom.

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http://dx.doi.org/10.1101/gad.302349.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666673PMC
September 2017

The p53 Family in Brain Disease.

Antioxid Redox Signal 2018 07 27;29(1):1-14. Epub 2017 Nov 27.

1 Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata," Rome, Italy .

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http://dx.doi.org/10.1089/ars.2017.7302DOI Listing
July 2018

Exploiting tumour addiction with a serine and glycine-free diet.

Cell Death Differ 2017 08 2;24(8):1311-1313. Epub 2017 Jun 2.

MRC Cancer Unit, Cambridge, UK.

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http://dx.doi.org/10.1038/cdd.2017.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520463PMC
August 2017

p73 Regulates Primary Cortical Neuron Metabolism: a Global Metabolic Profile.

Mol Neurobiol 2018 Apr 6;55(4):3237-3250. Epub 2017 May 6.

Department of Cancer Studies, University of Leicester, Leicester, LE2 7LX, UK.

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http://dx.doi.org/10.1007/s12035-017-0517-3DOI Listing
April 2018

p63 Adjusts Sugar Taste of Epidermal Layers.

J Invest Dermatol 2017 06 8;137(6):1204-1206. Epub 2017 Apr 8.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", 00133 Rome, Italy; Biochemistry Laboratory, Istituto Dermopatico Immacolata (IDI-IRCCS), 00100 Rome, Italy.

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http://dx.doi.org/10.1016/j.jid.2017.02.967DOI Listing
June 2017

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow.

Cell Death Differ 2017 05 7;24(5):844-854. Epub 2017 Apr 7.

Faculty of Dentistry, Division of Biomedical Sciences, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1038/cdd.2017.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423109PMC
May 2017

Tissue transglutaminase induction in the pressure-overloaded myocardium regulates matrix remodelling.

Cardiovasc Res 2017 Jul;113(8):892-905

Department of Medicine (Cardiology), Albert Einstein College of Medicine, The Wilf Family Cardiovascular Research Institute, Bronx, NY 10021, USA.

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http://dx.doi.org/10.1093/cvr/cvx053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852520PMC
July 2017

Transglutaminase 3 Protects against Photodamage.

J Invest Dermatol 2017 07 16;137(7):1590-1594. Epub 2017 Mar 16.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy; Istututo Dermopatico dell'Immacolata, IDI-IRCCS Biochemistry Laboratory, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.02.982DOI Listing
July 2017

TAp73 upregulates IL-1β in cancer cells: Potential biomarker in lung and breast cancer?

Biochem Biophys Res Commun 2017 01 3;482(3):498-505. Epub 2017 Feb 3.

MRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243147PMC
January 2017

Metabolic pathways regulated by p63.

Biochem Biophys Res Commun 2017 01 3;482(3):440-444. Epub 2017 Feb 3.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy; Medical Research Council, Toxicology Unit, Leicester LE1 9HN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.094DOI Listing
January 2017

Differential regulated microRNA by wild type and mutant p53 in induced pluripotent stem cells.

Cell Death Dis 2016 12 29;7(12):e2567. Epub 2016 Dec 29.

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/cddis.2016.419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260988PMC
December 2016

Characterization of TG2 and TG1-TG2 double knock-out mouse epidermis.

Amino Acids 2017 03 18;49(3):635-642. Epub 2016 Nov 18.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1007/s00726-016-2356-3DOI Listing
March 2017