Gernot Kleinberger

Gernot Kleinberger

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Gernot Kleinberger

Gernot Kleinberger

Publications by authors named "Gernot Kleinberger"

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Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease.

Alzheimers Dement 2016 12 14;12(12):1259-1272. Epub 2016 Jul 14.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.06.005DOI Listing
December 2016

The ε4 genotype modulates CSF YKL-40 levels and their structural brain correlates in the continuum of Alzheimer's disease but not those of sTREM2.

Alzheimers Dement (Amst) 2017 22;6:50-59. Epub 2016 Dec 22.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.dadm.2016.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266482PMC
December 2016

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.

EMBO Mol Med 2016 09 1;8(9):992-1004. Epub 2016 Sep 1.

Biomedical Center (BMC), Biochemistry, Ludwig-Maximilians-University Munich, Munich, Germany Munich Cluster for Systems Neurology (SyNergy), Munich, Germany German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany

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http://embomolmed.embopress.org/lookup/doi/10.15252/emmm.201
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http://dx.doi.org/10.15252/emmm.201606370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009806PMC
September 2016

Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study.

J Nucl Med 2016 06 18;57(6):954-60. Epub 2016 Feb 18.

Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany SyNergy, Ludwig-Maximilians-University of Munich, Munich, Germany; and

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http://dx.doi.org/10.2967/jnumed.115.167858DOI Listing
June 2016

Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin.

Neurobiol Aging 2016 Mar 29;39:220.e17-26. Epub 2015 Dec 29.

Biochemistry, Biomedical Center (BMC), Ludwig-Maximilians University, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases, DZNE, Munich, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.014DOI Listing
March 2016

Functional complementation in Drosophila to predict the pathogenicity of TARDBP variants: evidence for a loss-of-function mechanism.

Neurobiol Aging 2015 Feb 28;36(2):1121-9. Epub 2014 Sep 28.

Inserm U744, Institut Pasteur de Lille, Université de Lille Nord de France, Lille, France; Center for Medical Genetics, Ghent University Hospital, Gent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.001DOI Listing
February 2015

Mechanisms of granulin deficiency: lessons from cellular and animal models.

Mol Neurobiol 2013 Feb 13;47(1):337-60. Epub 2012 Dec 13.

Neurodegenerative Brain Diseases Group, VIB Department of Molecular Genetics, University of Antwerp-CDE, Universiteitsplein 1, Antwerp, 2610, Belgium.

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http://link.springer.com/10.1007/s12035-012-8380-8
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http://dx.doi.org/10.1007/s12035-012-8380-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538123PMC
February 2013

Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice.

J Pathol 2012 Sep 25;228(1):67-76. Epub 2012 Jun 25.

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.

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http://dx.doi.org/10.1002/path.4043DOI Listing
September 2012

The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

Biochem Soc Trans 2011 Aug;39(4):954-9

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, University of Antwerp-CDE, Antwerpen, Belgium.

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http://dx.doi.org/10.1042/BST0390954DOI Listing
August 2011

Increased caspase activation and decreased TDP-43 solubility in progranulin knockout cortical cultures.

J Neurochem 2010 Nov 24;115(3):735-47. Epub 2010 Sep 24.

Department of Molecular Genetics, VIB, Universiteitsplein 1, Antwerpen, Belgium.

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http://dx.doi.org/10.1111/j.1471-4159.2010.06961.xDOI Listing
November 2010