Publications by authors named "Gerjon J Ikink"

5Publications

Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance.

Authors:
Gerjon J Ikink Mandy Boer Elvira R M Bakker Annabel Vendel-Zwaagstra Chris Klijn Jelle Ten Hoeve Jos Jonkers Lodewyk F Wessels John Hilkens

Oncogene 2018 03 12;37(12):1594-1609. Epub 2018 Jan 12.

Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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March 2018

Insulin receptor substrate 4 (IRS4) is a constitutive active oncogenic driver collaborating with HER2 and causing therapeutic resistance.

Authors:
Gerjon J Ikink John Hilkens

Mol Cell Oncol 2017 17;4(2):e1279722. Epub 2017 Jan 17.

Division of Molecular Genetics, The Netherlands Cancer Institute , Amsterdam, the Netherlands.

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January 2017

IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation.

Authors:
Gerjon J Ikink Mandy Boer Elvira R M Bakker John Hilkens

Nat Commun 2016 11 23;7:13567. Epub 2016 Nov 23.

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, CX 1066 Amsterdam, The Netherlands.

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November 2016

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.

Authors:
John Hilkens Nikki C Timmer Mandy Boer Gerjon J Ikink Matthias Schewe Andrea Sacchetti Martijn A J Koppens Ji-Ying Song Elvira R M Bakker

Gut 2017 06 10;66(6):1095-1105. Epub 2016 Aug 10.

Department of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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June 2017

Calorie restriction in the filamentous fungus Podospora anserina.

Authors:
Anne D van Diepeningen S Marijke Slakhorst A Bertha Koopmanschap Gerjon J Ikink Alfons J M Debets Rolf F Hoekstra

Exp Gerontol 2010 Aug 11;45(7-8):516-24. Epub 2010 Jan 11.

Laboratory of Genetics, Plant Sciences, Wageningen University, Wageningen, The Netherlands.

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August 2010