Gerhard Bringmann

Gerhard Bringmann

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Gerhard Bringmann

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Atroposelective Total Synthesis of the Fourfold ortho-Substituted Naphthyltetrahydroisoquinoline Biaryl O,N-Dimethylhamatine.

Chemistry 2019 Sep 5. Epub 2019 Sep 5.

Department of Chemistry & Biochemistry, University of California, Santa Barbara, 93106, USA.

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http://dx.doi.org/10.1002/chem.201903832DOI Listing
September 2019

Dimeric naphthylisoquinoline alkaloids: polyketide-derived axially chiral bioactive quateraryls.

Nat Prod Rep 2019 May 28. Epub 2019 May 28.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1039/c9np00024kDOI Listing
May 2019

Capillary zone electrophoresis for the determination of amodiaquine and three of its synthetic impurities in pharmaceutical formulations.

Electrophoresis 2018 10 13;39(20):2530-2539. Epub 2018 Jun 13.

Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/elps.201800170DOI Listing
October 2018

Quality of the antimalarial medicine artemether - lumefantrine in 8 cities of the Democratic Republic of the Congo.

Drug Test Anal 2018 Oct 18;10(10):1599-1606. Epub 2018 Jul 18.

Institute of Organic Chemistry, University of Würzburg, Germany.

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http://dx.doi.org/10.1002/dta.2420DOI Listing
October 2018

Ancistroyafungines A-D, 5,8'- and 5,1'-coupled naphthylisoquinoline alkaloids from a Congolese Ancistrocladus species, with antiausterity activities against human PANC-1 pancreatic cancer cells.

Fitoterapia 2018 Oct 27;130:6-16. Epub 2018 Jul 27.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany; Department of Chemistry, University of Pretoria, Pretoria 0001, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2018.07.017DOI Listing
October 2018

Ancistrolikokine I and further 5,8'-coupled naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus likoko and their cytotoxic activities against drug-sensitive and multidrug resistant human leukemia cells.

Fitoterapia 2018 Sep 22;129:114-125. Epub 2018 Jun 22.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2018.06.009DOI Listing
September 2018

Ancistrocyclinones A and B, unprecedented pentacyclic N,C-coupled naphthylisoquinoline alkaloids, from the Chinese liana Ancistrocladus tectorius.

Org Biomol Chem 2018 02;16(9):1581-1590

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1039/c7ob03092dDOI Listing
February 2018

Antiprotozoal Spirombandakamines A and A, Fused Naphthylisoquinoline Dimers from a Congolese Ancistrocladus Plant.

Org Lett 2017 12 30;19(24):6740-6743. Epub 2017 Nov 30.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.orglett.7b03473DOI Listing
December 2017

1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Alters Cell Cycle Progression in Human Neuroblastoma Cell Lines.

Neurotox Res 2017 Nov 18;32(4):649-660. Epub 2017 Jul 18.

Neuroinflammation Research Group, South Asian University, Chanakyapuri, New Delhi, India.

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http://dx.doi.org/10.1007/s12640-017-9782-1DOI Listing
November 2017

Antileukemic ancistrobenomine B and related 5,1'-coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius.

Fitoterapia 2017 Sep 6;121:76-85. Epub 2017 Jul 6.

Institute of Pharmacy and Biochemistry, Department of Pharmaceutical Biology, University of Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.

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http://dx.doi.org/10.1016/j.fitote.2017.07.001DOI Listing
September 2017

Metallocorroles as inherently chiral chromophores: resolution and electronic circular dichroism spectroscopy of a tungsten biscorrole.

Chem Commun (Camb) 2017 Jun;53(45):6121-6124

Institute of Organic Chemistry, University of Würzburg, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1039/c7cc02027aDOI Listing
June 2017

Gardenifolins A-H, Scalemic Neolignans from Gardenia ternifolia: Chiral Resolution, Configurational Assignment, and Cytotoxic Activities against the HeLa Cancer Cell Line.

J Nat Prod 2017 05 10;80(5):1604-1614. Epub 2017 May 10.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00180DOI Listing
May 2017

Cyclombandakamines A and A, Oxygen-Bridged Naphthylisoquinoline Dimers from a Congolese Ancistrocladus Liana.

Org Lett 2017 03 23;19(6):1342-1345. Epub 2017 Feb 23.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.orglett.7b00209DOI Listing
March 2017

The Plant-Derived Naphthoquinone Droserone Inhibits In Vitro Measles Virus Infection.

Planta Med 2017 Feb 15;83(3-04):232-238. Epub 2016 Jul 15.

Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1055/s-0042-111825DOI Listing
February 2017

Krishnadimer A, an Axially Chiral Non-biaryl Natural Product: Discovery and Biomimetic Synthesis.

Org Lett 2017 01 19;19(1):182-185. Epub 2016 Dec 19.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, Würzburg D-97074, Germany.

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http://dx.doi.org/10.1021/acs.orglett.6b03479DOI Listing
January 2017

Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from the Chinese liana Ancistrocladus tectorius.

Fitoterapia 2016 Dec 19;115:1-8. Epub 2016 Sep 19.

Institute of Pharmacy and Biochemistry, Department of Pharmaceutical Biology, University of Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.

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http://dx.doi.org/10.1016/j.fitote.2016.09.009DOI Listing
December 2016

Directed Synthesis of All Four Pure Stereoisomers of the N,C-Coupled Naphthylisoquinoline Alkaloid Ancistrocladinium A.

Org Lett 2016 12 1;18(24):6508-6511. Epub 2016 Dec 1.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.orglett.6b03480DOI Listing
December 2016

Rotationally Hindered Biphenyls and Terphenyls: Synthesis, Molecular Dynamics, and Configurational Assignment.

J Org Chem 2016 11 25;81(22):10721-10732. Epub 2016 Oct 25.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.joc.6b01804DOI Listing
November 2016

Generation of Dicoordinate Boron(I) Units by Fragmentation of a Tetra-Boron(I) Molecular Square.

Angew Chem Int Ed Engl 2016 11 12;55(46):14464-14468. Epub 2016 Oct 12.

Institut für Anorganische Chemie, Julius-Maximilians Universität Würzburg, Am Hubland, 97074, Würzburg, Germany.

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http://dx.doi.org/10.1002/anie.201608429DOI Listing
November 2016

HIV-inhibitory michellamine-type dimeric naphthylisoquinoline alkaloids from the Central African liana Ancistrocladus congolensis.

Phytochemistry 2016 Aug 29;128:71-81. Epub 2016 Apr 29.

Institute of Virology and Immunology, University of Würzburg, Versbacher Straße 7, D-97078 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2016.04.005DOI Listing
August 2016

Trangmolins A-F with an Unprecedented Structural Plasticity of the Rings A and B: New Insight into Limonoid Biosynthesis.

Chemistry 2016 Aug 7;22(33):11719-27. Epub 2016 Jul 7.

Institute of Organic Chemistry, University Würzburg, Am Hubland, Würzburg, 97074, Germany.

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http://dx.doi.org/10.1002/chem.201602230DOI Listing
August 2016

Axially Chiral Dimeric Naphthalene and Naphthoquinone Metabolites, from Root Cultures of the West African Liana Triphyophyllum peltatum.

J Nat Prod 2016 08 20;79(8):2094-103. Epub 2016 Jul 20.

Institute of Pharmacy, Research Group Pharmaceutical Biology, University of Leipzig , Johannisallee 21-23, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.6b00439DOI Listing
August 2016

First Atroposelective Total Synthesis of Enantiomerically Pure Ancistrocladidine and Ancistrotectorine.

Chemistry 2016 Jul 6;22(28):9792-6. Epub 2016 Jun 6.

Institut für Organische Chemie, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany.

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http://dx.doi.org/10.1002/chem.201600701DOI Listing
July 2016

Rational quality assessment procedure for less-investigated herbal medicines: Case of a Congolese antimalarial drug with an analytical report.

Fitoterapia 2016 Apr 20;110:189-95. Epub 2016 Mar 20.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2016.03.012DOI Listing
April 2016

Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.

J Med Chem 2016 Mar 17;59(5):2067-82. Epub 2016 Feb 17.

Pharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Universität Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01674DOI Listing
March 2016

Axial, Helical, and Planar Chirality in Directly Linked Basket-Handle Porphyrin Arrays.

J Org Chem 2016 Feb 12;81(3):1075-88. Epub 2016 Jan 12.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.joc.5b02638DOI Listing
February 2016

Monomeric Chiral and Achiral Basket-Handle Porphyrins: Synthesis, Structural Features, and Arrested Tautomerism.

J Org Chem 2015 Dec 13;80(24):12359-78. Epub 2015 Nov 13.

Institute of Organic Chemistry and ‡Institute of Inorganic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/acs.joc.5b02259DOI Listing
December 2015

Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability.

Chemistry 2015 Oct 13;21(41):14507-18. Epub 2015 Aug 13.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg (Germany).

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http://dx.doi.org/10.1002/chem.201501657DOI Listing
October 2015

Stereoisomeric Composition of Natural Myrtucommulone A.

J Nat Prod 2015 Oct 12;78(10):2381-9. Epub 2015 Oct 12.

Nees-Institute for Biodiversity of Plants, University of Bonn , Meckenheimer Allee 170, 53115 Bonn, Germany.

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http://pubs.acs.org/doi/10.1021/acs.jnatprod.5b00358
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http://dx.doi.org/10.1021/acs.jnatprod.5b00358DOI Listing
October 2015

Antiviral Limonoids Including Khayanolides from the Trang Mangrove Plant Xylocarpus moluccensis.

J Nat Prod 2015 Jul 26;78(7):1570-8. Epub 2015 Jun 26.

⊥Institute of Organic Chemistry, University of Würzburg, Am Hubland, Würzburg 97074, Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.5b00151DOI Listing
July 2015

Chemical attenuation of Plasmodium in the liver modulates severe malaria disease progression.

J Immunol 2015 May 10;194(10):4860-70. Epub 2015 Apr 10.

Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, D 69120 Heidelberg, Germany; German Centre for Infection Research, D 69120 Heidelberg, Germany;

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http://www.jimmunol.org/content/early/2015/04/10/jimmunol.14
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1400863
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http://dx.doi.org/10.4049/jimmunol.1400863DOI Listing
May 2015

Anti-trypanosomal activities and structural chemical properties of selected compound classes.

Parasitol Res 2015 Feb 23;114(2):501-12. Epub 2014 Nov 23.

Laboratory of Molecular Physiology, Institute of Experimental Medicine, School of Medicine Luis Razetti, Faculty of Medicine, Universidad Central de Venezuela, Caracas, Venezuela,

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http://dx.doi.org/10.1007/s00436-014-4210-4DOI Listing
February 2015

Modelling antibiotic and cytotoxic isoquinoline effects in Staphylococcus aureus, Staphylococcus epidermidis and mammalian cells.

Int J Med Microbiol 2015 Jan 27;305(1):96-109. Epub 2014 Nov 27.

Department of Bioinformatics, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany; EMBL Heidelberg, BioComputing Unit, Meyerhofstraße 1, 69117 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2014.11.006DOI Listing
January 2015

Chiral and achiral basket-handle porphyrins: short synthesis and stereostructures of these versatile building blocks.

Org Lett 2015 Jan 5;17(2):210-3. Epub 2015 Jan 5.

Institute of Organic Chemistry, University of Würzburg , Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/ol503286sDOI Listing
January 2015

Axially chiral BODIPY DYEmers: an apparent exception to the exciton chirality rule.

Angew Chem Int Ed Engl 2014 Dec 29;53(52):14592-5. Epub 2014 Oct 29.

Institut für Organische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg (Germany).

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http://dx.doi.org/10.1002/anie.201408398DOI Listing
December 2014

C,C- and N,C-coupled dimers of 2-aminotetraphenylporphyrins: regiocontrolled synthesis, spectroscopic properties, and quantum-chemical calculations.

Chemistry 2014 Apr 26;20(14):3998-4006. Epub 2014 Feb 26.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg (Germany), Fax: (+49) 931-31-84755.

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http://dx.doi.org/10.1002/chem.201304169DOI Listing
April 2014

Decandrinin, an unprecedented C9-spiro-fused 7,8-seco-ent-abietane from the Godavari mangrove Ceriops decandra.

Beilstein J Org Chem 2014 27;10:276-81. Epub 2014 Jan 27.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, Würzburg 97074, Germany.

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http://dx.doi.org/10.3762/bjoc.10.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943825PMC
March 2014

Nature's lab for derivatization: new and revised structures of a variety of streptophenazines produced by a sponge-derived Streptomyces strain.

Mar Drugs 2014 Mar 25;12(4):1699-714. Epub 2014 Mar 25.

Kiel Center for Marine Natural Products at the Helmholtz Center for Ocean Research (GEOMAR), Am Kiel-Kanal 44, Kiel 24106, Germany.

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http://dx.doi.org/10.3390/md12041699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012441PMC
March 2014

A primaquine-chloroquine hybrid with dual activity against Plasmodium liver and blood stages.

Int J Med Microbiol 2013 Dec 5;303(8):539-47. Epub 2013 Aug 5.

Institute of Organic Chemistry, University of Wuerzburg, Am Hubland, D-97074 Wuerzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2013.07.005DOI Listing
December 2013

New bhimamycins from Streptomyces sp. AK 671.

J Antibiot (Tokyo) 2013 Dec 18;66(12):719-26. Epub 2013 Sep 18.

Institut für Organische Chemie, Universität Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1038/ja.2013.82DOI Listing
December 2013

Pestalotiopens A and B: stereochemically challenging flexible sesquiterpene-cyclopaldic acid hybrids from Pestalotiopsis sp.

Chemistry 2013 Nov 2;19(46):15556-64. Epub 2013 Oct 2.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg (Germany), Fax: (+49)931-3184755.

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http://dx.doi.org/10.1002/chem.201302204DOI Listing
November 2013

Regiodivergent N-C and N-N aryl coupling reactions of indoloterpenes and cycloether formation mediated by a single bacterial flavoenzyme.

Angew Chem Int Ed Engl 2013 Aug 10;52(34):9040-3. Epub 2013 Jul 10.

Dept. of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstr. 11a, 07745 Jena, Germany.

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http://dx.doi.org/10.1002/anie.201303733DOI Listing
August 2013

Highly selective antiplasmodial naphthylisoquinoline alkaloids from Ancistrocladus tectorius.

Phytochemistry 2013 Jul 27;91:220-8. Epub 2012 Mar 27.

Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2012.02.017DOI Listing
July 2013

Thaixylomolins A-C: limonoids featuring two new motifs from the Thai Xylocarpus moluccensis.

Org Lett 2013 Jul 2;15(14):3682-5. Epub 2013 Jul 2.

Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, PR China.

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http://dx.doi.org/10.1021/ol401556mDOI Listing
July 2013

Mbandakamines A and B, unsymmetrically coupled dimeric naphthylisoquinoline alkaloids, from a Congolese Ancistrocladus species.

Org Lett 2013 Jun 13;15(11):2590-3. Epub 2013 May 13.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/ol4005883DOI Listing
June 2013

Siamese-twin porphyrin: a pyrazole-based expanded porphyrin of persistent helical conformation.

Chemistry 2013 May 9;19(19):5868-80. Epub 2013 Apr 9.

Institute of Inorganic Chemistry, University of Göttingen, Tammannstr. 4, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1002/chem.201204296DOI Listing
May 2013

SpecDis: quantifying the comparison of calculated and experimental electronic circular dichroism spectra.

Chirality 2013 Apr;25(4):243-9

Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/chir.22138DOI Listing
April 2013

Helicusin E, isochromophilone X and isochromophilone XI: new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.

Mar Drugs 2013 Mar 12;11(3):800-16. Epub 2013 Mar 12.

Kiel Centre for Marine Natural Products at the Helmholtz Centre for Ocean Research (GEOMAR), Kiel 24106, Germany.

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http://dx.doi.org/10.3390/md11030800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705371PMC
March 2013

New tetromycin derivatives with anti-trypanosomal and protease inhibitory activities.

Mar Drugs 2011 26;9(10):1682-97. Epub 2011 Sep 26.

Julius-von-Sachs Institute for Biological Sciences, University of Würzburg, Julius-von-Sachs-Platz 3, Würzburg 97082, Germany.

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http://dx.doi.org/10.3390/md9101682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210601PMC
February 2013

Jozimine A2: the first dimeric Dioncophyllaceae-type naphthylisoquinoline alkaloid, with three chiral axes and high antiplasmodial activity.

Chemistry 2013 Jan 5;19(3):916-23. Epub 2012 Dec 5.

Institut für Organische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://doi.wiley.com/10.1002/chem.201202755
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http://dx.doi.org/10.1002/chem.201202755DOI Listing
January 2013

Nudicaulins, yellow flower pigments of Papaver nudicaule: revised constitution and assignment of absolute configuration.

Org Lett 2013 Jan 18;15(1):156-9. Epub 2012 Dec 18.

Max Planck Institute for Chemical Ecology, Hans-Knöll-Strasse 8, Beutenberg Campus, 07745 Jena, Germany.

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http://dx.doi.org/10.1021/ol303211wDOI Listing
January 2013

Synthesis, optical resolution, absolute configuration, and osteogenic activity of cis-pterocarpans.

Org Biomol Chem 2012 Dec 6;10(48):9583-92. Epub 2012 Sep 6.

Division of Medicinal and Process Chemistry, CSIR - Central Drug Research Institute, Lucknow 226001, India.

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http://xlink.rsc.org/?DOI=c2ob25722j
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http://dx.doi.org/10.1039/c2ob25722jDOI Listing
December 2012

Andhraxylocarpins A-E: structurally intriguing limonoids from the true mangroves Xylocarpus granatum and Xylocarpus moluccensis.

Chemistry 2012 Nov 24;18(45):14342-51. Epub 2012 Sep 24.

Key Laboratory of Marine Bioresources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, 510301 Guangzhou, PR China.

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http://dx.doi.org/10.1002/chem.201202356DOI Listing
November 2012

Atroposelective Heck macrocyclization: enantioselective synthesis of bis(bibenzylic) natural products.

Org Lett 2012 Sep 23;14(17):4548-51. Epub 2012 Aug 23.

Department of Organic Chemistry, Saarland University, Campus, 66123 Saarbrücken, Germany.

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http://pubs.acs.org/doi/10.1021/ol302132s
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http://dx.doi.org/10.1021/ol302132sDOI Listing
September 2012

Marilines A-C: novel phthalimidines from the sponge-derived fungus Stachylidium sp.

Chemistry 2012 Jul 18;18(28):8827-34. Epub 2012 Jun 18.

Institute for Pharmaceutical Biology, University of Bonn, Nussallee 6, 53115 Bonn, Germany.

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http://dx.doi.org/10.1002/chem.201103278DOI Listing
July 2012

Ultrafast exciton dynamics after Soret- or Q-band excitation of a directly β,β'-linked bisporphyrin.

Phys Chem Chem Phys 2012 Jun 1;14(22):8038-50. Epub 2012 May 1.

Institut für Physikalische und Theoretische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1039/c2cp23608gDOI Listing
June 2012

Anti-tumoral activities of dioncoquinones B and C and related naphthoquinones gained from total synthesis or isolation from plants.

Eur J Med Chem 2011 Dec 16;46(12):5778-89. Epub 2011 Sep 16.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ejmech.2011.09.012DOI Listing
December 2011

Quantitative detection of C-deuterated drugs by CARS microscopy and Raman microspectroscopy.

Analyst 2011 Sep 25;136(18):3686-93. Epub 2011 Jul 25.

Institute of Photonic Technologies, Albert-Einstein-Straße 9, 07745 Jena, Germany.

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http://dx.doi.org/10.1039/c0an00956cDOI Listing
September 2011

Ethics, chemistry, and education for sustainability.

Angew Chem Int Ed Engl 2011 Sep 27;50(37):8482-90. Epub 2011 Jul 27.

Universität Bayreuth, Hudo-Rüdel-Strasse 8, 95445 Bayreuth, Germany.

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http://dx.doi.org/10.1002/anie.201007599DOI Listing
September 2011

Fenton's oxidation: a tool for the investigation of potential drug metabolites.

J Pharm Biomed Anal 2011 Apr 21;54(5):1047-58. Epub 2010 Dec 21.

Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.jpba.2010.12.016DOI Listing
April 2011

Phenalinolactones A-D, terpenoglycoside antibiotics from Streptomyces sp. Tü 6071.

J Antibiot (Tokyo) 2011 Mar 22;64(3):229-32. Epub 2010 Dec 22.

Mikrobiologisches Institut, Universität Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/ja.2010.165DOI Listing
March 2011

Atroposelective total synthesis of axially chiral biaryl natural products.

Chem Rev 2011 Feb 12;111(2):563-639. Epub 2010 Oct 12.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, Germany.

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http://dx.doi.org/10.1021/cr100155eDOI Listing
February 2011

Chloropupukeanolides C-E: cytotoxic pupukeanane chlorides with a spiroketal skeleton from Pestalotiopsis fici.

Chemistry 2011 Feb 8;17(9):2604-13. Epub 2011 Feb 8.

Key Laboratory of Systematic Mycology & Lichenology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P R China.

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http://doi.wiley.com/10.1002/chem.201003129
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February 2011

Aspergiolides C and D: spirocyclic aromatic polyketides with potent protein kinase c-Met inhibitory effects.

Chemistry 2011 Jan 3;17(4):1319-26. Epub 2010 Dec 3.

Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, P.R. China.

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http://doi.wiley.com/10.1002/chem.201001547
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January 2011

Very-long-chain aldehydes promote in vitro prepenetration processes of Blumeria graminis in a dose- and chain length-dependent manner.

New Phytol 2010 Dec 20;188(4):1039-54. Epub 2010 Aug 20.

Universität Würzburg, Julius-von-Sachs-Institut für Biowissenschaften, Lehrstuhl für Botanik II, Julius-von-Sachs-Platz 3, D-97082 Würzburg, Germany.

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http://doi.wiley.com/10.1111/j.1469-8137.2010.03419.x
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http://dx.doi.org/10.1111/j.1469-8137.2010.03419.xDOI Listing
December 2010

Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties.

J Nat Prod 2010 Dec 16;73(12):2035-41. Epub 2010 Nov 16.

Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-Universität, Freiburg, Germany.

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http://dx.doi.org/10.1021/np100523sDOI Listing
December 2010

QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids.

Eur J Med Chem 2010 Nov 17;45(11):5370-83. Epub 2010 Sep 17.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ejmech.2010.08.062DOI Listing
November 2010

Baculiferins A-O, O-sulfated pyrrole alkaloids with anti-HIV-1 activity, from the Chinese marine sponge Iotrochota baculifera.

Bioorg Med Chem 2010 Aug 23;18(15):5466-74. Epub 2010 Jun 23.

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, People's Republic of China.

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http://dx.doi.org/10.1016/j.bmc.2010.06.052DOI Listing
August 2010

Shuangancistrotectorines A-E, dimeric naphthylisoquinoline alkaloids with three chiral biaryl axes from the Chinese plant Ancistrocladus tectorius.

Chemistry 2010 Apr;16(14):4206-16

Institut für Organische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1002/chem.200903247DOI Listing
April 2010

[Search for new drugs from natural sources. Marine sponges: cornucopia of the marine].

Pharm Unserer Zeit 2010 ;39(1):62-6

Julius-von-Sachs-Institut für Biowissenschaften, Universität Würzburg, Julius-von-Sachs-Platz 3, 97082 Würzburg.

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http://dx.doi.org/10.1002/pauz.201000354DOI Listing
March 2010

Convergence in the biosynthesis of acetogenic natural products from plants, fungi, and bacteria.

Phytochemistry 2009 Oct-Nov;70(15-16):1776-86. Epub 2009 Sep 26.

Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2009.08.019DOI Listing
January 2010

Total synthesis of the N,C-coupled naphthylisoquinoline alkaloids ancistrocladinium A and B and related analogues.

J Am Chem Soc 2010 Jan;132(3):1151-8

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://pubs.acs.org/doi/abs/10.1021/ja9097687
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January 2010

Synthesis and stereochemistry of highly unsymmetric beta,meso-linked porphyrin arrays.

J Org Chem 2009 Nov;74(21):8005-20

Institute of Organic Chemistry and Rontgen Research Center for Complex Material Systems, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://pubs.acs.org/doi/abs/10.1021/jo901483q
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November 2009

Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinone chrysophanol.

Chem Commun (Camb) 2009 Nov 5(44):6810-2. Epub 2009 Oct 5.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1039/b910501hDOI Listing
November 2009

Identification of L-ferritin in neuromelanin granules of the human substantia nigra: a targeted proteomics approach.

Mol Cell Proteomics 2009 Aug 24;8(8):1832-8. Epub 2009 Mar 24.

Clinic and Polyclinic for Psychiatry and Psychotherapy, Julius-Maximilians-Universität Würzburg, Füchsleinstrasse 15, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1074/mcp.M900006-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722774PMC
August 2009

Synthesis and helicate formation of a new family of BINOL-based bis(bipyridine) ligands.

J Am Chem Soc 2009 Mar;131(10):3621-30

Kekule-Institute of Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Strasse 1, D-53121 Bonn, Germany.

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http://dx.doi.org/10.1021/ja807780jDOI Listing
March 2009

Cleavage of four carbon-carbon bonds during biosynthesis of the griseorhodin a spiroketal pharmacophore.

J Am Chem Soc 2009 Feb;131(6):2297-305

Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, 53121 Bonn, Germany.

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http://dx.doi.org/10.1021/ja807827kDOI Listing
February 2009

Axially chiral beta,beta'-bisporphyrins: synthesis and configurational stability tuned by the central metals.

J Am Chem Soc 2008 Dec;130(52):17812-5

Institute of Organic Chemistry and Röntgen Research Center for Complex Material Systems, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1021/ja8055886DOI Listing
December 2008

Knipholone and related 4-phenylanthraquinones: structurally, pharmacologically, and biosynthetically remarkable natural products.

Nat Prod Rep 2008 Aug 23;25(4):696-718. Epub 2008 Jun 23.

Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://xlink.rsc.org/?DOI=b803784c
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August 2008