Gerhard A Coetzee

Gerhard A Coetzee

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Gerhard A Coetzee

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MCF-7 as a model for functional analysis of breast cancer risk variants.

Cancer Epidemiol Biomarkers Prev 2019 Jul 10. Epub 2019 Jul 10.

Center for Neurodegenerative Science, Van Andel Research Institute

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http://dx.doi.org/10.1158/1055-9965.EPI-19-0066DOI Listing
July 2019

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

Authors:
Stephanie L Schmit Christopher K Edlund Fredrick R Schumacher Jian Gong Tabitha A Harrison Jeroen R Huyghe Chenxu Qu Marilena Melas David J Van Den Berg Hansong Wang Stephanie Tring Sarah J Plummer Demetrius Albanes M Henar Alonso Christopher I Amos Kristen Anton Aaron K Aragaki Volker Arndt Elizabeth L Barry Sonja I Berndt Stéphane Bezieau Stephanie Bien Amanda Bloomer Juergen Boehm Marie-Christine Boutron-Ruault Hermann Brenner Stefanie Brezina Daniel D Buchanan Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Jose E Castelao Andrew T Chan Jenny Chang-Claude Stephen J Chanock Iona Cheng Ya-Wen Cheng Lee Soo Chin James M Church Timothy Church Gerhard A Coetzee Michelle Cotterchio Marcia Cruz Correa Keith R Curtis David Duggan Douglas F Easton Dallas English Edith J M Feskens Rocky Fischer Liesel M FitzGerald Barbara K Fortini Lars G Fritsche Charles S Fuchs Manuela Gago-Dominguez Manish Gala Steven J Gallinger W James Gauderman Graham G Giles Edward L Giovannucci Stephanie M Gogarten Clicerio Gonzalez-Villalpando Elena M Gonzalez-Villalpando William M Grady Joel K Greenson Andrea Gsur Marc Gunter Christopher A Haiman Jochen Hampe Sophia Harlid John F Harju Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Shu-Chen Huang Jose Maria Huerta Thomas J Hudson David J Hunter Gregory E Idos Motoki Iwasaki Rebecca D Jackson Eric J Jacobs Sun Ha Jee Mark A Jenkins Wei-Hua Jia Shuo Jiao Amit D Joshi Laurence N Kolonel Suminori Kono Charles Kooperberg Vittorio Krogh Tilman Kuehn Sébastien Küry Andrea LaCroix Cecelia A Laurie Flavio Lejbkowicz Mathieu Lemire Heinz-Josef Lenz David Levine Christopher I Li Li Li Wolfgang Lieb Yi Lin Noralane M Lindor Yun-Ru Liu Fotios Loupakis Yingchang Lu Frank Luh Jing Ma Christoph Mancao Frank J Manion Sanford D Markowitz Vicente Martin Koichi Matsuda Keitaro Matsuo Kevin J McDonnell Caroline E McNeil Roger Milne Antonio J Molina Bhramar Mukherjee Neil Murphy Polly A Newcomb Kenneth Offit Hanane Omichessan Domenico Palli Jesus P Paredes Cotoré Julyann Pérez-Mayoral Paul D Pharoah John D Potter Conghui Qu Leon Raskin Gad Rennert Hedy S Rennert Bridget M Riggs Clemens Schafmayer Robert E Schoen Thomas A Sellers Daniela Seminara Gianluca Severi Wei Shi David Shibata Xiao-Ou Shu Erin M Siegel Martha L Slattery Melissa Southey Zsofia K Stadler Mariana C Stern Sebastian Stintzing Darin Taverna Stephen N Thibodeau Duncan C Thomas Antonia Trichopoulou Shoichiro Tsugane Cornelia M Ulrich Franzel J B van Duijnhoven Bethany van Guelpan Joseph Vijai Jarmo Virtamo Stephanie J Weinstein Emily White Aung Ko Win Alicja Wolk Michael Woods Anna H Wu Kana Wu Yong-Bing Xiang Yun Yen Brent W Zanke Yi-Xin Zeng Ben Zhang Niha Zubair Sun-Seog Kweon Jane C Figueiredo Wei Zheng Loic Le Marchand Annika Lindblom Victor Moreno Ulrike Peters Graham Casey Li Hsu David V Conti Stephen B Gruber

J Natl Cancer Inst 2019 Feb;111(2):146-157

Department of Preventive Medicine, USC Norris Comprehensive Cancer Center.

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http://dx.doi.org/10.1093/jnci/djy099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555904PMC
February 2019

Genetically engineered stem cell-derived neurons can be rendered resistant to alpha-synuclein aggregate pathology.

Eur J Neurosci 2019 Feb 20;49(3):316-319. Epub 2019 Jan 20.

Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan.

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http://doi.wiley.com/10.1111/ejn.14333
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http://dx.doi.org/10.1111/ejn.14333DOI Listing
February 2019

CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops.

Genome Biol 2018 10 8;19(1):160. Epub 2018 Oct 8.

Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1450 Biggy Street, NRT 6503, Los Angeles, CA, 90089-9601, USA.

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https://genomebiology.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13059-018-1531-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176514PMC
October 2018

Parkinson's disease genetic risk in a midbrain neuronal cell line.

Neurobiol Dis 2018 06 24;114:53-64. Epub 2018 Feb 24.

Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.02.007DOI Listing
June 2018

Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits.

Epigenetics Chromatin 2016 9;9:50. Epub 2016 Nov 9.

Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1450 Biggy Street, NRT G511B, Los Angeles, CA 90089-9601 USA.

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http://dx.doi.org/10.1186/s13072-016-0102-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103450PMC
January 2018

The Five Dimensions of Parkinson's Disease Genetic Risk.

J Parkinsons Dis 2018 ;8(1):13-15

Van Andel Research Institute, Grand Rapids, MI, USA.

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http://dx.doi.org/10.3233/JPD-171256DOI Listing
January 2018

Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes.

PLoS One 2017 13;12(4):e0175882. Epub 2017 Apr 13.

Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI, United States.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0175882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391096PMC
April 2017

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

Authors:
Christopher I Amos Joe Dennis Zhaoming Wang Jinyoung Byun Fredrick R Schumacher Simon A Gayther Graham Casey David J Hunter Thomas A Sellers Stephen B Gruber Alison M Dunning Kyriaki Michailidou Laura Fachal Kimberly Doheny Amanda B Spurdle Yafang Li Xiangjun Xiao Jane Romm Elizabeth Pugh Gerhard A Coetzee Dennis J Hazelett Stig E Bojesen Charlisse Caga-Anan Christopher A Haiman Ahsan Kamal Craig Luccarini Daniel Tessier Daniel Vincent François Bacot David J Van Den Berg Stefanie Nelson Stephen Demetriades David E Goldgar Fergus J Couch Judith L Forman Graham G Giles David V Conti Heike Bickeböller Angela Risch Melanie Waldenberger Irene Brüske-Hohlfeld Belynda D Hicks Hua Ling Lesley McGuffog Andrew Lee Karoline Kuchenbaecker Penny Soucy Judith Manz Julie M Cunningham Katja Butterbach Zsofia Kote-Jarai Peter Kraft Liesel FitzGerald Sara Lindström Marcia Adams James D McKay Catherine M Phelan Sara Benlloch Linda E Kelemen Paul Brennan Marjorie Riggan Tracy A O'Mara Hongbing Shen Yongyong Shi Deborah J Thompson Marc T Goodman Sune F Nielsen Andrew Berchuck Sylvie Laboissiere Stephanie L Schmit Tameka Shelford Christopher K Edlund Jack A Taylor John K Field Sue K Park Kenneth Offit Mads Thomassen Rita Schmutzler Laura Ottini Rayjean J Hung Jonathan Marchini Ali Amin Al Olama Ulrike Peters Rosalind A Eeles Michael F Seldin Elizabeth Gillanders Daniela Seminara Antonis C Antoniou Paul D P Pharoah Georgia Chenevix-Trench Stephen J Chanock Jacques Simard Douglas F Easton

Cancer Epidemiol Biomarkers Prev 2017 01 3;26(1):126-135. Epub 2016 Oct 3.

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224974PMC
January 2017

Reducing GWAS Complexity.

Cell Cycle 2016 ;15(1):22-4

b Departments of Preventive Medicine and Urology , USC/Norris Cancer Center , USA.

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http://dx.doi.org/10.1080/15384101.2015.1120928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825730PMC
October 2016

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.

J Natl Cancer Inst 2016 Jul 27;108(7). Epub 2016 Jan 27.

Affiliations of authors: Department of Preventive Medicine (YH, KAR, DJH, SAI, FRS, GC, LCP, XS, GAC, DOS, DVC, BEH, CAH) and Department of Urology (GAC), Keck School of Medicine, and Norris Comprehensive Cancer Center (SAI, FRS, GC, GAC, DOS, DVC, BEH, CAH), University of Southern California , Los Angeles, CA ; University of Arizona College of Medicine and University of Arizona Cancer Center , Tucson, AZ (RAK); Department of Epidemiology (SSS) and Department of Urology (CAP), University of Texas M. D. Anderson Cancer Center , Houston, TX ; Department of Public Health Sciences (BAR) and Department of Public Health Sciences (CND), Henry Ford Hospital , Detroit, MI ; Department of Preventive Medicine, Stony Brook University , Stony Brook, NY (BN, MCL, SYW, AJMH); James Buchanan Brady Urological Institute, Johns Hopkins Hospital and Medical Institution , Baltimore, MD (WBI); Division of Public Health Sciences (JLS, SK) and SWOG Statistical Center (PJG), Fred Hutchinson Cancer Research Center , Seattle, WA ; Department of Epidemiology, School of Public Health, University of Washington , Seattle, WA (JLS); Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine , Nashville, TN (WZ, WJB); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , Bethesda, MD (SIB, ZW, MBC, SJC); Cancer Genomics Research Laboratory, NCI-DCEG, SAIC-Frederick Inc. , Frederick, MD (ZW); Program for Personalized Cancer Care and Department of Surgery, NorthShore University HealthSystem , Evanston, IL (JX); Department of Genetics (NR, DR, AT, AA, DQ, SM) and Howard Hughes Medical Institute (DR, SM), Harvard Medical School, Harvard University , Boston, MA ; Broad Institute of MIT and Harvard , Cambridge, MA (NR, DR, AT, AA, DQ, SM); Department of Pathology and Laboratory Medicine and Department of Human Genetics, David Geffen School of Medicine, University of California , Los Angeles, Los Angeles, CA (BP); Howard Hughes Medical Institute, Department of Medicine, School of Medicine, University of California , San Diego, San Diego, CA (DN, MGR, RSJ); Epidemiology Research Program, American Cancer Society , Atlanta, GA (SMG, VLS); Korle Bu Teaching Hospital , Accra , Ghana (EDY, YT, RBB, AAA, ET); University of Ghana Medical School , Accra , Ghana (EDY, YT, RBB, AAA, ET); Westat , Rockville, MD (AT, SN); School of Public Health, University of California , Berkeley, Berkeley, CA (APC); Cancer Prevention Institute of California , Fremont, CA (EMJ, AWH, LC); Stanford University School of Medicine and Stanford Cancer Institute , Palo Alto, CA (EMJ, AWH, LC); Department of Urology, Northwestern University , Chicago, IL (ABM); Department of Epidemiology, Harvard School of Public Health , Boston, MA (LBS, WJB); The Translational Genomics Research Institute , Phoenix, AZ (JC); Chronic Disease Research Centre and Faculty of Medical Sciences, University of the West Indies , Bridgetown, Barbados (AJMH); Glickman Urological & Kidney Institute, Cleveland Clinic , Cleveland, OH (EAK); Center for Cancer Genomics, Wake Forest School of Medicine , Winston-Salem, NC (SLZ); Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California , San Francisco, San Francisco, CA (JSW); School of Public Health, Makerere University College of Health Sciences , Kampala, Uganda (AL, SW); Uro Care , Kampala , Uganda (SW).

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http://dx.doi.org/10.1093/jnci/djv431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948565PMC
July 2016

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology.

Sci Rep 2016 07 27;6:30509. Epub 2016 Jul 27.

Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, USA.

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http://dx.doi.org/10.1038/srep30509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962314PMC
July 2016

4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus.

Sci Rep 2016 Mar 3;6:22462. Epub 2016 Mar 3.

Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1038/srep22462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776156PMC
March 2016

motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites.

Bioinformatics 2015 Dec 12;31(23):3847-9. Epub 2015 Aug 12.

Bioinformatics and Computational Biology Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA and.

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http://dx.doi.org/10.1093/bioinformatics/btv470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653394PMC
December 2015

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.

PLoS One 2015 18;10(2):e0117758. Epub 2015 Feb 18.

Institute for Genetic Medicine, University of Southern California, Los Angeles, United States of America; University of Southern California /Norris Comprehensive Cancer Center, Los Angeles, United States of America; Department of Cell & Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, United States of America; Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117758PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333349PMC
November 2015

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.

Authors:
Kate Lawrenson Edwin S Iversen Jonathan Tyrer Rachel Palmieri Weber Patrick Concannon Dennis J Hazelett Qiyuan Li Jeffrey R Marks Andrew Berchuck Janet M Lee Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Elisa V Bandera Yukie Bean Matthias W Beckmann Maria Bisogna Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Fiona Bruinsma Ralf Butzow Ian G Campbell Karen Carty Jenny Chang-Claude Georgia Chenevix-Trench Ann Chen Zhihua Chen Linda S Cook Daniel W Cramer Julie M Cunningham Cezary Cybulski Joanna Plisiecka-Halasa Joe Dennis Ed Dicks Jennifer A Doherty Thilo Dörk Andreas du Bois Diana Eccles Douglas T Easton Robert P Edwards Ursula Eilber Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Ellen L Goode Marc T Goodman Jacek Gronwald Philipp Harter Hanis Nazihah Hasmad Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Estrid Hogdall Claus Hogdall Satoyo Hosono Anna Jakubowska James Paul Allan Jensen Beth Y Karlan Susanne Kruger Kjaer Linda E Kelemen Melissa Kellar Joseph L Kelley Lambertus A Kiemeney Camilla Krakstad Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Rikki Cannioto Arto Leminen Jenny Lester Douglas A Levine Dong Liang Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Heli Nevanlinna Iain McNeish Usha Menon Francesmary Modugno Kirsten B Moysich Steven A Narod Lotte Nedergaard Roberta B Ness Mat Adenan Noor Azmi Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic Celeste L Pearce Tanja Pejovic Liisa M Pelttari Jennifer Permuth-Wey Catherine M Phelan Malcolm C Pike Elizabeth M Poole Susan J Ramus Harvey A Risch Barry Rosen Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Agnieszka Budzilowska Thomas A Sellers Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Lara Sucheston Ingvild L Tangen Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Agnieszka Timorek Shelley S Tworoger Els Van Nieuwenhuysen Ignace Vergote Robert A Vierkant Shan Wang-Gohrke Christine Walsh Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Yin-Ling Woo Xifeng Wu Anna H Wu Hannah Yang Wei Zheng Argyrios Ziogas Gerhard A Coetzee Matthew L Freedman Alvaro N A Monteiro Joanna Moes-Sosnowska Jolanta Kupryjanczyk Paul D Pharoah Simon A Gayther Joellen M Schildkraut

Carcinogenesis 2015 Nov 29;36(11):1341-53. Epub 2015 Sep 29.

Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA, Cancer Control and Population Sciences, Duke Cancer Institute, Durham, NC 27710, USA,

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http://dx.doi.org/10.1093/carcin/bgv138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635670PMC
November 2015

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.

Hum Mol Genet 2015 Oct 29;24(19):5589-602. Epub 2015 May 29.

Division of Genetics and Epidemiology, The Institute of Cancer Research & Royal Marsden NHS Foundation Trust, London, UK,

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http://hmg.oxfordjournals.org/content/24/19/5589.full.pdf
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572072PMC
October 2015

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.

Hum Mol Genet 2015 Oct 10;24(19):5603-18. Epub 2015 Jul 10.

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center,

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http://dx.doi.org/10.1093/hmg/ddv269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572069PMC
October 2015

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Authors:
Fredrick R Schumacher Stephanie L Schmit Shuo Jiao Christopher K Edlund Hansong Wang Ben Zhang Li Hsu Shu-Chen Huang Christopher P Fischer John F Harju Gregory E Idos Flavio Lejbkowicz Frank J Manion Kevin McDonnell Caroline E McNeil Marilena Melas Hedy S Rennert Wei Shi Duncan C Thomas David J Van Den Berg Carolyn M Hutter Aaron K Aragaki Katja Butterbach Bette J Caan Christopher S Carlson Stephen J Chanock Keith R Curtis Charles S Fuchs Manish Gala Edward L Giovannucci Stephanie M Gogarten Richard B Hayes Brian Henderson David J Hunter Rebecca D Jackson Laurence N Kolonel Charles Kooperberg Sébastien Küry Andrea LaCroix Cathy C Laurie Cecelia A Laurie Mathieu Lemire David Levine Jing Ma Karen W Makar Conghui Qu Darin Taverna Cornelia M Ulrich Kana Wu Suminori Kono Dee W West Sonja I Berndt Stephane Bezieau Hermann Brenner Peter T Campbell Andrew T Chan Jenny Chang-Claude Gerhard A Coetzee David V Conti David Duggan Jane C Figueiredo Barbara K Fortini Steven J Gallinger W James Gauderman Graham Giles Roger Green Robert Haile Tabitha A Harrison Michael Hoffmeister John L Hopper Thomas J Hudson Eric Jacobs Motoki Iwasaki Sun Ha Jee Mark Jenkins Wei-Hua Jia Amit Joshi Li Li Noralene M Lindor Keitaro Matsuo Victor Moreno Bhramar Mukherjee Polly A Newcomb John D Potter Leon Raskin Gad Rennert Stephanie Rosse Gianluca Severi Robert E Schoen Daniela Seminara Xiao-Ou Shu Martha L Slattery Shoichiro Tsugane Emily White Yong-Bing Xiang Brent W Zanke Wei Zheng Loic Le Marchand Graham Casey Stephen B Gruber Ulrike Peters

Nat Commun 2015 Oct 26;6:8739. Epub 2015 Oct 26.

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http://dx.doi.org/10.1038/ncomms9739DOI Listing
October 2015

Genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Authors:
Fredrick R Schumacher Stephanie L Schmit Shuo Jiao Christopher K Edlund Hansong Wang Ben Zhang Li Hsu Shu-Chen Huang Christopher P Fischer John F Harju Gregory E Idos Flavio Lejbkowicz Frank J Manion Kevin McDonnell Caroline E McNeil Marilena Melas Hedy S Rennert Wei Shi Duncan C Thomas David J Van Den Berg Carolyn M Hutter Aaron K Aragaki Katja Butterbach Bette J Caan Christopher S Carlson Stephen J Chanock Keith R Curtis Charles S Fuchs Manish Gala Edward L Giovannucci Stephanie M Gogarten Richard B Hayes Brian Henderson David J Hunter Rebecca D Jackson Laurence N Kolonel Charles Kooperberg Sébastien Küry Andrea LaCroix Cathy C Laurie Cecelia A Laurie Mathieu Lemire David Levine Jing Ma Karen W Makar Conghui Qu Darin Taverna Cornelia M Ulrich Kana Wu Suminori Kono Dee W West Sonja I Berndt Stéphane Bezieau Hermann Brenner Peter T Campbell Andrew T Chan Jenny Chang-Claude Gerhard A Coetzee David V Conti David Duggan Jane C Figueiredo Barbara K Fortini Steven J Gallinger W James Gauderman Graham Giles Roger Green Robert Haile Tabitha A Harrison Michael Hoffmeister John L Hopper Thomas J Hudson Eric Jacobs Motoki Iwasaki Sun Ha Jee Mark Jenkins Wei-Hua Jia Amit Joshi Li Li Noralene M Lindor Keitaro Matsuo Victor Moreno Bhramar Mukherjee Polly A Newcomb John D Potter Leon Raskin Gad Rennert Stephanie Rosse Gianluca Severi Robert E Schoen Daniela Seminara Xiao-Ou Shu Martha L Slattery Shoichiro Tsugane Emily White Yong-Bing Xiang Brent W Zanke Wei Zheng Loic Le Marchand Graham Casey Stephen B Gruber Ulrike Peters

Nat Commun 2015 Jul 7;6:7138. Epub 2015 Jul 7.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA.

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http://dx.doi.org/10.1038/ncomms8138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967357PMC
July 2015

Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension.

Invest Ophthalmol Vis Sci 2015 Apr;56(4):2737-48

USC Institute for Genetic Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, California, United States 2USC Eye Institute/Department of Ophthalmology, Keck School of Medicine of USC, University of Southern California.

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http://dx.doi.org/10.1167/iovs.14-14803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416661PMC
April 2015

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Sonja I Berndt David V Conti Fredrick Schumacher Ying Han Sara Benlloch Dennis J Hazelett Zhaoming Wang Ed Saunders Daniel Leongamornlert Sara Lindstrom Sara Jugurnauth-Little Tokhir Dadaev Malgorzata Tymrakiewicz Daniel O Stram Kristin Rand Peggy Wan Alex Stram Xin Sheng Loreall C Pooler Karen Park Lucy Xia Jonathan Tyrer Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Merideth Yeager Laurie Burdette Charles C Chung Amy Hutchinson Kai Yu Chee Goh Mahbubl Ahmed Koveela Govindasami Michelle Guy Teuvo L J Tammela Anssi Auvinen Tiina Wahlfors Johanna Schleutker Tapio Visakorpi Katri A Leinonen Jianfeng Xu Markus Aly Jenny Donovan Ruth C Travis Tim J Key Afshan Siddiq Federico Canzian Kay-Tee Khaw Atsushi Takahashi Michiaki Kubo Paul Pharoah Nora Pashayan Maren Weischer Borge G Nordestgaard Sune F Nielsen Peter Klarskov Martin Andreas Røder Peter Iversen Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Janet L Stanford Suzanne Kolb Sarah Holt Beatrice Knudsen Antonio Hurtado Coll Susan M Gapstur W Ryan Diver Victoria L Stevens Christiane Maier Manuel Luedeke Kathleen Herkommer Antje E Rinckleb Sara S Strom Curtis Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Lisa Cannon-Albright Cezary Cybulski Dominika Wokołorczyk Wojciech Kluźniak Jong Park Thomas Sellers Hui-Yi Lin William B Isaacs Alan W Partin Hermann Brenner Aida Karina Dieffenbach Christa Stegmaier Constance Chen Edward L Giovannucci Jing Ma Meir Stampfer Kathryn L Penney Lorelei Mucci Esther M John Sue A Ingles Rick A Kittles Adam B Murphy Hardev Pandha Agnieszka Michael Andrzej M Kierzek William Blot Lisa B Signorello Wei Zheng Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Barbara Nemesure John Carpten Cristina Leske Suh-Yuh Wu Anselm Hennis Adam S Kibel Benjamin A Rybicki Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein S Lilly Zheng Jyotsna Batra Judith Clements Amanda Spurdle Manuel R Teixeira Paula Paulo Sofia Maia Chavdar Slavov Radka Kaneva Vanio Mitev John S Witte Graham Casey Elizabeth M Gillanders Daniella Seminara Elio Riboli Freddie C Hamdy Gerhard A Coetzee Qiyuan Li Matthew L Freedman David J Hunter Kenneth Muir Henrik Gronberg David E Neal Melissa Southey Graham G Giles Gianluca Severi Michael B Cook Hidewaki Nakagawa Fredrik Wiklund Peter Kraft Stephen J Chanock Brian E Henderson Douglas F Easton Rosalind A Eeles Christopher A Haiman

Nat Genet 2014 Oct 14;46(10):1103-9. Epub 2014 Sep 14.

1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [2] Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. [3].

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http://dx.doi.org/10.1038/ng.3094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383163PMC
October 2014

Comprehensive functional annotation of seventy-one breast cancer risk Loci.

PLoS One 2013 22;8(5):e63925. Epub 2013 May 22.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063925PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661550PMC
April 2014

Comprehensive functional annotation of 77 prostate cancer risk loci.

PLoS Genet 2014 Jan 30;10(1):e1004102. Epub 2014 Jan 30.

Departments of Urology and Preventive Medicine, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907334PMC
January 2014

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

Int J Cancer 2013 Dec 6;133(12):2812-23. Epub 2013 Jul 6.

Cancer Biology Group, Freemasons Foundation Centre for Men's Health, Basil Hetzel Institute for Translational Health Research, Department of Medicine, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.1002/ijc.28310DOI Listing
December 2013

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

Authors:
Jennifer Permuth-Wey Kate Lawrenson Howard C Shen Aneliya Velkova Jonathan P Tyrer Zhihua Chen Hui-Yi Lin Y Ann Chen Ya-Yu Tsai Xiaotao Qu Susan J Ramus Rod Karevan Janet Lee Nathan Lee Melissa C Larson Katja K Aben Hoda Anton-Culver Natalia Antonenkova Antonis C Antoniou Sebastian M Armasu François Bacot Laura Baglietto Elisa V Bandera Jill Barnholtz-Sloan Matthias W Beckmann Michael J Birrer Greg Bloom Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Robert Brown Ralf Butzow Qiuyin Cai Ian Campbell Jenny Chang-Claude Stephen Chanock Georgia Chenevix-Trench Jin Q Cheng Mine S Cicek Gerhard A Coetzee Linda S Cook Fergus J Couch Daniel W Cramer Julie M Cunningham Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Douglas F Easton Diana Eccles Robert Edwards Arif B Ekici Peter A Fasching David A Fenstermacher James M Flanagan Montserrat Garcia-Closas Aleksandra Gentry-Maharaj Graham G Giles Rosalind M Glasspool Jesus Gonzalez-Bosquet Marc T Goodman Martin Gore Bohdan Górski Jacek Gronwald Per Hall Mari K Halle Philipp Harter Florian Heitz Peter Hillemanns Maureen Hoatlin Claus K Høgdall Estrid Høgdall Satoyo Hosono Anna Jakubowska Allan Jensen Heather Jim Kimberly R Kalli Beth Y Karlan Stanley B Kaye Linda E Kelemen Lambertus A Kiemeney Fumitaka Kikkawa Gottfried E Konecny Camilla Krakstad Susanne Krüger Kjaer Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Johnathan M Lancaster Nhu D Le Arto Leminen Douglas A Levine Dong Liang Boon Kiong Lim Jie Lin Jolanta Lissowska Karen H Lu Jan Lubiński Galina Lurie Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Usha Menon Francesmary Modugno Kirsten B Moysich Toru Nakanishi Steven A Narod Lotte Nedergaard Roberta B Ness Heli Nevanlinna Stefan Nickels Houtan Noushmehr Kunle Odunsi Sara H Olson Irene Orlow James Paul Celeste L Pearce Tanja Pejovic Liisa M Pelttari Malcolm C Pike Elizabeth M Poole Paola Raska Stefan P Renner Harvey A Risch Lorna Rodriguez-Rodriguez Mary Anne Rossing Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Gianluca Severi Viji Shridhar Xiao-Ou Shu Yurii B Shvetsov Weiva Sieh Honglin Song Melissa C Southey Beata Spiewankiewicz Daniel Stram Rebecca Sutphen Soo-Hwang Teo Kathryn L Terry Daniel C Tessier Pamela J Thompson Shelley S Tworoger Anne M van Altena Ignace Vergote Robert A Vierkant Daniel Vincent Allison F Vitonis Shan Wang-Gohrke Rachel Palmieri Weber Nicolas Wentzensen Alice S Whittemore Elisabeth Wik Lynne R Wilkens Boris Winterhoff Yin Ling Woo Anna H Wu Yong-Bing Xiang Hannah P Yang Wei Zheng Argyrios Ziogas Famida Zulkifli Catherine M Phelan Edwin Iversen Joellen M Schildkraut Andrew Berchuck Brooke L Fridley Ellen L Goode Paul D P Pharoah Alvaro N A Monteiro Thomas A Sellers Simon A Gayther

Nat Commun 2013 ;4:1627

Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709460PMC
October 2013

Biological implications and regulatory mechanisms of long-range chromosomal interactions.

J Biol Chem 2013 Aug 18;288(31):22369-77. Epub 2013 Jun 18.

Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829327PMC
August 2013

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

Authors:
Keri L Monda Gary K Chen Kira C Taylor Cameron Palmer Todd L Edwards Leslie A Lange Maggie C Y Ng Adebowale A Adeyemo Matthew A Allison Lawrence F Bielak Guanjie Chen Mariaelisa Graff Marguerite R Irvin Suhn K Rhie Guo Li Yongmei Liu Youfang Liu Yingchang Lu Michael A Nalls Yan V Sun Mary K Wojczynski Lisa R Yanek Melinda C Aldrich Adeyinka Ademola Christopher I Amos Elisa V Bandera Cathryn H Bock Angela Britton Ulrich Broeckel Quiyin Cai Neil E Caporaso Chris S Carlson John Carpten Graham Casey Wei-Min Chen Fang Chen Yii-Der I Chen Charleston W K Chiang Gerhard A Coetzee Ellen Demerath Sandra L Deming-Halverson Ryan W Driver Patricia Dubbert Mary F Feitosa Ye Feng Barry I Freedman Elizabeth M Gillanders Omri Gottesman Xiuqing Guo Talin Haritunians Tamara Harris Curtis C Harris Anselm J M Hennis Dena G Hernandez Lorna H McNeill Timothy D Howard Barbara V Howard Virginia J Howard Karen C Johnson Sun J Kang Brendan J Keating Suzanne Kolb Lewis H Kuller Abdullah Kutlar Carl D Langefeld Guillaume Lettre Kurt Lohman Vaneet Lotay Helen Lyon Joann E Manson William Maixner Yan A Meng Kristine R Monroe Imran Morhason-Bello Adam B Murphy Josyf C Mychaleckyj Rajiv Nadukuru Katherine L Nathanson Uma Nayak Amidou N'diaye Barbara Nemesure Suh-Yuh Wu M Cristina Leske Christine Neslund-Dudas Marian Neuhouser Sarah Nyante Heather Ochs-Balcom Adesola Ogunniyi Temidayo O Ogundiran Oladosu Ojengbede Olufunmilayo I Olopade Julie R Palmer Edward A Ruiz-Narvaez Nicholette D Palmer Michael F Press Evandine Rampersaud Laura J Rasmussen-Torvik Jorge L Rodriguez-Gil Babatunde Salako Eric E Schadt Ann G Schwartz Daniel A Shriner David Siscovick Shad B Smith Sylvia Wassertheil-Smoller Elizabeth K Speliotes Margaret R Spitz Lara Sucheston Herman Taylor Bamidele O Tayo Margaret A Tucker David J Van Den Berg Digna R Velez Edwards Zhaoming Wang John K Wiencke Thomas W Winkler John S Witte Margaret Wrensch Xifeng Wu James J Yang Albert M Levin Taylor R Young Neil A Zakai Mary Cushman Krista A Zanetti Jing Hua Zhao Wei Zhao Yonglan Zheng Jie Zhou Regina G Ziegler Joseph M Zmuda Jyotika K Fernandes Gary S Gilkeson Diane L Kamen Kelly J Hunt Ida J Spruill Christine B Ambrosone Stefan Ambs Donna K Arnett Larry Atwood Diane M Becker Sonja I Berndt Leslie Bernstein William J Blot Ingrid B Borecki Erwin P Bottinger Donald W Bowden Gregory Burke Stephen J Chanock Richard S Cooper Jingzhong Ding David Duggan Michele K Evans Caroline Fox W Timothy Garvey Jonathan P Bradfield Hakon Hakonarson Struan F A Grant Ann Hsing Lisa Chu Jennifer J Hu Dezheng Huo Sue A Ingles Esther M John Joanne M Jordan Edmond K Kabagambe Sharon L R Kardia Rick A Kittles Phyllis J Goodman Eric A Klein Laurence N Kolonel Loic Le Marchand Simin Liu Barbara McKnight Robert C Millikan Thomas H Mosley Badri Padhukasahasram L Keoki Williams Sanjay R Patel Ulrike Peters Curtis A Pettaway Patricia A Peyser Bruce M Psaty Susan Redline Charles N Rotimi Benjamin A Rybicki Michèle M Sale Pamela J Schreiner Lisa B Signorello Andrew B Singleton Janet L Stanford Sara S Strom Michael J Thun Mara Vitolins Wei Zheng Jason H Moore Scott M Williams Shamika Ketkar Xiaofeng Zhu Alan B Zonderman Charles Kooperberg George J Papanicolaou Brian E Henderson Alex P Reiner Joel N Hirschhorn Ruth J F Loos Kari E North Christopher A Haiman

Nat Genet 2013 Jun 14;45(6):690-6. Epub 2013 Apr 14.

The Center for Observational Research, Amgen, Inc. Thousand Oaks, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694490PMC
June 2013

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.

Gastroenterology 2013 Apr 22;144(4):799-807.e24. Epub 2012 Dec 22.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636812PMC
April 2013

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

Authors:
Montserrat Garcia-Closas Fergus J Couch Sara Lindstrom Kyriaki Michailidou Marjanka K Schmidt Mark N Brook Nick Orr Suhn Kyong Rhie Elio Riboli Heather S Feigelson Loic Le Marchand Julie E Buring Diana Eccles Penelope Miron Peter A Fasching Hiltrud Brauch Jenny Chang-Claude Jane Carpenter Andrew K Godwin Heli Nevanlinna Graham G Giles Angela Cox John L Hopper Manjeet K Bolla Qin Wang Joe Dennis Ed Dicks Will J Howat Nils Schoof Stig E Bojesen Diether Lambrechts Annegien Broeks Irene L Andrulis Pascal Guénel Barbara Burwinkel Elinor J Sawyer Antoinette Hollestelle Olivia Fletcher Robert Winqvist Hermann Brenner Arto Mannermaa Ute Hamann Alfons Meindl Annika Lindblom Wei Zheng Peter Devillee Mark S Goldberg Jan Lubinski Vessela Kristensen Anthony Swerdlow Hoda Anton-Culver Thilo Dörk Kenneth Muir Keitaro Matsuo Anna H Wu Paolo Radice Soo Hwang Teo Xiao-Ou Shu William Blot Daehee Kang Mikael Hartman Suleeporn Sangrajrang Chen-Yang Shen Melissa C Southey Daniel J Park Fleur Hammet Jennifer Stone Laura J Van't Veer Emiel J Rutgers Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Julian Peto Michael G Schrauder Arif B Ekici Matthias W Beckmann Isabel Dos Santos Silva Nichola Johnson Helen Warren Ian Tomlinson Michael J Kerin Nicola Miller Federick Marme Andreas Schneeweiss Christof Sohn Therese Truong Pierre Laurent-Puig Pierre Kerbrat Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne Jose Ignacio Arias Perez Primitiva Menéndez Heiko Müller Volker Arndt Christa Stegmaier Peter Lichtner Magdalena Lochmann Christina Justenhoven Yon-Dschun Ko Taru A Muranen Kristiina Aittomäki Carl Blomqvist Dario Greco Tuomas Heikkinen Hidemi Ito Hiroji Iwata Yasushi Yatabe Natalia N Antonenkova Sara Margolin Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Rosemary Balleine Chiu-Chen Tseng David Van Den Berg Daniel O Stram Patrick Neven Anne-Sophie Dieudonné Karin Leunen Anja Rudolph Stefan Nickels Dieter Flesch-Janys Paolo Peterlongo Bernard Peissel Loris Bernard Janet E Olson Xianshu Wang Kristen Stevens Gianluca Severi Laura Baglietto Catriona McLean Gerhard A Coetzee Ye Feng Brian E Henderson Fredrick Schumacher Natalia V Bogdanova France Labrèche Martine Dumont Cheng Har Yip Nur Aishah Mohd Taib Ching-Yu Cheng Martha Shrubsole Jirong Long Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Julia A Knight Gord Glendon Anna Marie Mulligan Robertus A E M Tollenaar Caroline M Seynaeve Mieke Kriege Maartje J Hooning Ans M W van den Ouweland Carolien H M van Deurzen Wei Lu Yu-Tang Gao Hui Cai Sabapathy P Balasubramanian Simon S Cross Malcolm W R Reed Lisa Signorello Qiuyin Cai Mitul Shah Hui Miao Ching Wan Chan Kee Seng Chia Anna Jakubowska Katarzyna Jaworska Katarzyna Durda Chia-Ni Hsiung Pei-Ei Wu Jyh-Cherng Yu Alan Ashworth Michael Jones Daniel C Tessier Anna González-Neira Guillermo Pita M Rosario Alonso Daniel Vincent Francois Bacot Christine B Ambrosone Elisa V Bandera Esther M John Gary K Chen Jennifer J Hu Jorge L Rodriguez-Gil Leslie Bernstein Michael F Press Regina G Ziegler Robert M Millikan Sandra L Deming-Halverson Sarah Nyante Sue A Ingles Quinten Waisfisz Helen Tsimiklis Enes Makalic Daniel Schmidt Minh Bui Lorna Gibson Bertram Müller-Myhsok Rita K Schmutzler Rebecca Hein Norbert Dahmen Lars Beckmann Kirsimari Aaltonen Kamila Czene Astrid Irwanto Jianjun Liu Clare Turnbull Nazneen Rahman Hanne Meijers-Heijboer Andre G Uitterlinden Fernando Rivadeneira Curtis Olswold Susan Slager Robert Pilarski Foluso Ademuyiwa Irene Konstantopoulou Nicholas G Martin Grant W Montgomery Dennis J Slamon Claudia Rauh Michael P Lux Sebastian M Jud Thomas Bruning Joellen Weaver Priyanka Sharma Harsh Pathak Will Tapper Sue Gerty Lorraine Durcan Dimitrios Trichopoulos Rosario Tumino Petra H Peeters Rudolf Kaaks Daniele Campa Federico Canzian Elisabete Weiderpass Mattias Johansson Kay-Tee Khaw Ruth Travis Françoise Clavel-Chapelon Laurence N Kolonel Constance Chen Andy Beck Susan E Hankinson Christine D Berg Robert N Hoover Jolanta Lissowska Jonine D Figueroa Daniel I Chasman Mia M Gaudet W Ryan Diver Walter C Willett David J Hunter Jacques Simard Javier Benitez Alison M Dunning Mark E Sherman Georgia Chenevix-Trench Stephen J Chanock Per Hall Paul D P Pharoah Celine Vachon Douglas F Easton Christopher A Haiman Peter Kraft

Nat Genet 2013 Apr;45(4):392-8, 398e1-2

1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK. [2] Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK. [3].

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April 2013

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

Authors:
Afshan Siddiq Fergus J Couch Gary K Chen Sara Lindström Diana Eccles Robert C Millikan Kyriaki Michailidou Daniel O Stram Lars Beckmann Suhn Kyong Rhie Christine B Ambrosone Kristiina Aittomäki Pilar Amiano Carmel Apicella Laura Baglietto Elisa V Bandera Matthias W Beckmann Christine D Berg Leslie Bernstein Carl Blomqvist Hiltrud Brauch Louise Brinton Quang M Bui Julie E Buring Saundra S Buys Daniele Campa Jane E Carpenter Daniel I Chasman Jenny Chang-Claude Constance Chen Françoise Clavel-Chapelon Angela Cox Simon S Cross Kamila Czene Sandra L Deming Robert B Diasio W Ryan Diver Alison M Dunning Lorraine Durcan Arif B Ekici Peter A Fasching Heather Spencer Feigelson Laura Fejerman Jonine D Figueroa Olivia Fletcher Dieter Flesch-Janys Mia M Gaudet Susan M Gerty Jorge L Rodriguez-Gil Graham G Giles Carla H van Gils Andrew K Godwin Nikki Graham Dario Greco Per Hall Susan E Hankinson Arndt Hartmann Rebecca Hein Judith Heinz Robert N Hoover John L Hopper Jennifer J Hu Scott Huntsman Sue A Ingles Astrid Irwanto Claudine Isaacs Kevin B Jacobs Esther M John Christina Justenhoven Rudolf Kaaks Laurence N Kolonel Gerhard A Coetzee Mark Lathrop Loic Le Marchand Adam M Lee I-Min Lee Timothy Lesnick Peter Lichtner Jianjun Liu Eiliv Lund Enes Makalic Nicholas G Martin Catriona A McLean Hanne Meijers-Heijboer Alfons Meindl Penelope Miron Kristine R Monroe Grant W Montgomery Bertram Müller-Myhsok Stefan Nickels Sarah J Nyante Curtis Olswold Kim Overvad Domenico Palli Daniel J Park Julie R Palmer Harsh Pathak Julian Peto Paul Pharoah Nazneen Rahman Fernando Rivadeneira Daniel F Schmidt Rita K Schmutzler Susan Slager Melissa C Southey Kristen N Stevens Hans-Peter Sinn Michael F Press Eric Ross Elio Riboli Paul M Ridker Fredrick R Schumacher Gianluca Severi Isabel Dos Santos Silva Jennifer Stone Malin Sund William J Tapper Michael J Thun Ruth C Travis Clare Turnbull Andre G Uitterlinden Quinten Waisfisz Xianshu Wang Zhaoming Wang Joellen Weaver Rüdiger Schulz-Wendtland Lynne R Wilkens David Van Den Berg Wei Zheng Regina G Ziegler Elad Ziv Heli Nevanlinna Douglas F Easton David J Hunter Brian E Henderson Stephen J Chanock Montserrat Garcia-Closas Peter Kraft Christopher A Haiman Celine M Vachon

Hum Mol Genet 2012 Dec 13;21(24):5373-84. Epub 2012 Sep 13.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.

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December 2012

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs.

Nucleic Acids Res 2012 Oct 8;40(18):e139. Epub 2012 Jun 8.

Norris Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467035PMC
October 2012

Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client.

J Mol Endocrinol 2012 Oct 25;49(2):57-68. Epub 2012 Jul 25.

Cancer Biology Group, Level 1 Basil Hetzel Institute for Translational Health Research, Freemasons Foundation Centre for Men's Health, Queen Elizabeth Hospital, University of Adelaide, 28 Woodville Road, Woodville South, Adelaide, South Australia 5011, Australia.

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October 2012

An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.

Dis Model Mech 2012 May 25;5(3):366-74. Epub 2012 Jan 25.

Department of Biochemistry and Molecular Biology, Norris Cancer Center, USC Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA.

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May 2012

Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.

Nucleic Acids Res 2012 Apr 19;40(8):3538-47. Epub 2011 Dec 19.

Department of Biochemistry and Molecular Biology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333873PMC
April 2012

A noncoding RNA antisense to moesin at 5p14.1 in autism.

Sci Transl Med 2012 Apr;4(128):128ra40

Program in Biomedical and Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.

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April 2012

Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.

J Clin Endocrinol Metab 2012 Mar 21;97(3):E393-9. Epub 2011 Dec 21.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Children's Hospital Los Angeles, 1441 Eastlake Avenue, MC-9175, Los Angeles, California 90033, USA.

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March 2012

The usefulness of prostate cancer genome-wide association studies.

J Urol 2012 Jan 16;187(1):9-10. Epub 2011 Nov 16.

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January 2012

Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells.

Mol Cell Biol 2011 Dec 3;31(23):4648-62. Epub 2011 Oct 3.

Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232925PMC
December 2011

Identification and functional annotation of GWAS risk SNPs.

Cell Cycle 2011 Dec 1;10(23):3995-6. Epub 2011 Dec 1.

Keck School of Medicince, University of Southern California, Los Angeles, CA, USA.

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December 2011

TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.

PLoS One 2011 Jan 18;6(1):e16205. Epub 2011 Jan 18.

Department of Molecular Microbiology and Immunology, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022761PMC
January 2011

Hypertension, diuretics and antihypertensives in relation to bladder cancer.

Carcinogenesis 2010 Nov 23;31(11):1964-71. Epub 2010 Aug 23.

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1093/carcin/bgq173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966553PMC
November 2010

Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.

Mol Cancer 2010 Sep 23;9:258. Epub 2010 Sep 23.

Department of Biochemistry & Molecular Biology, University of Southern California, Los Angeles, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955618PMC
September 2010

Regulation of adult bone turnover by sex steroids.

J Cell Physiol 2010 Aug;224(2):305-10

Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770230PMC
August 2010

A systematic approach to understand the functional consequences of non-protein coding risk regions.

Cell Cycle 2010 Jan 23;9(2):256-9. Epub 2010 Jan 23.

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.4161/cc.9.2.10419DOI Listing
January 2010

Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA.

Mol Endocrinol 2009 Aug 23;23(8):1203-14. Epub 2009 Apr 23.

Department Biochemistry and Molecular Biology, Institute of Genetic Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718746PMC
August 2009

Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer.

Cancer Res 2009 Aug 28;69(15):6131-40. Epub 2009 Jul 28.

Dame Roma Mitchell Cancer Research Laboratories, Discipline of Medicine, University of Adelaide, Hanson Institute, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0452DOI Listing
August 2009

Location, location, (ChIP-)location! Mapping chromatin landscapes one immunoprecipitation at a time.

J Cell Biochem 2009 May;107(1):1-5

USC Epigenome Center, University of Southern California, Los Angeles, California 90033, USA.

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http://doi.wiley.com/10.1002/jcb.22133
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748114PMC
May 2009

Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions.

Prostate 2009 Mar;69(4):392-400

Department of Biochemistry & Molecular Biology, USC Keck School of Medicine, Los Angeles, California 90033, USA.

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http://doi.wiley.com/10.1002/pros.20893
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March 2009

Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.

Endocrinology 2008 Dec 28;149(12):5984-95. Epub 2008 Aug 28.

Department of Urology, Preventive Medicine, Norris Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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December 2008

Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer.

Carcinogenesis 2008 Jul 9;29(7):1386-93. Epub 2008 Jun 9.

The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720058PMC
July 2008

Control of androgen receptor signaling in prostate cancer by the cochaperone small glutamine rich tetratricopeptide repeat containing protein alpha.

Cancer Res 2007 Oct;67(20):10087-96

Dame Roma Mitchell Cancer Research Laboratories, School of Medicine, The University of Adelaide/Hanson Institute, Adelaide, South Australia, Australia.

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October 2007

Androgen receptor-mediated repression of novel target genes.

Prostate 2007 Sep;67(13):1371-83

Department of Preventive Medicine, Norris Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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September 2007

Identification of novel androgen receptor target genes in prostate cancer.

Mol Cancer 2007 Jun 6;6:39. Epub 2007 Jun 6.

Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904239PMC
June 2007

Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma.

Cancer Epidemiol Biomarkers Prev 2006 Nov;15(11):2285-91

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90089-9175, USA.

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November 2006

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells.

Cancer Cell 2006 Jun;9(6):435-43

Department of Urology, Biochemistry, and Molecular Biology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1016/j.ccr.2006.04.020DOI Listing
June 2006

Molecular chaperones throughout the life cycle of the androgen receptor.

Cancer Lett 2006 Jan;231(1):12-9

Department of Urology and Preventive Medicine, Norris Cancer Center, USC Keck School of Medicine, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1016/j.canlet.2004.12.037DOI Listing
January 2006

Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?

Endocr Rev 2005 Dec 26;26(7):898-915. Epub 2005 Aug 26.

Department of Molecular and Medical Pharmacology, 650 Charles E. Young Drive, Center for Health Sciences 23-234, University of California Los Angeles School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1210/er.2003-0034DOI Listing
December 2005

The androgen receptor: unlocking the secrets of its unique transactivation domain.

Vitam Horm 2005 ;71:301-19

Department of Urology and Preventive Medicine, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1016/S0083-6729(05)71010-4DOI Listing
November 2005

Androgen receptor-dependent PSA expression in androgen-independent prostate cancer cells does not involve androgen receptor occupancy of the PSA locus.

Cancer Res 2005 Sep;65(17):8003-8

Department of Urology and Preventive Medicine, Norris Cancer Center, USC Keck School of Medicine, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-3679DOI Listing
September 2005

GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor.

Biol Chem 2005 Jan;386(1):69-74

Departments of Urology and Preventive Medicine, Norris Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1515/BC.2005.009DOI Listing
January 2005

Prostate specific antigen gene regulation by androgen receptor.

J Cell Biochem 2004 Oct;93(2):233-41

Department of Molecular Microbiology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1002/jcb.20228DOI Listing
October 2004

PC-3 cells with enhanced androgen receptor signaling: a model for clonal selection in prostate cancer.

Prostate 2004 Sep;60(4):352-66

Dame Roma Mitchell Cancer Research Laboratories, Department of Medicine, University of Adelaide/Hanson Institute, Adelaide, Southern Australia, Australia.

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http://doi.wiley.com/10.1002/pros.20079
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September 2004

Structural and functional consequences of glutamine tract variation in the androgen receptor.

Hum Mol Genet 2004 Aug 15;13(16):1677-92. Epub 2004 Jun 15.

Dame Roma Mitchell Cancer Research Laboratories, Adelaide University/Hanson Institute, SA, Australia.

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http://dx.doi.org/10.1093/hmg/ddh181DOI Listing
August 2004

Carotenoids/vitamin C and smoking-related bladder cancer.

Int J Cancer 2004 Jun;110(3):417-23

USC/Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089-9181, USA.

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http://dx.doi.org/10.1002/ijc.20104DOI Listing
June 2004

Androgen receptor signaling: mechanism of interleukin-6 inhibition.

Cancer Res 2004 Apr;64(7):2619-26

Department of Urology and Preventive Medicine, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA.

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April 2004

Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor.

Nucleic Acids Res 2003 Dec;31(23):6741-7

Department of Urology, Norris Cancer Center, USC Keck School of Medicine, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1093/nar/gkg909DOI Listing
December 2003

The androgen receptor CAG repeat and prostate cancer risk.

Methods Mol Med 2003 ;81:255-66

Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1385/1-59259-372-0:255DOI Listing
June 2003

Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms.

Mol Cancer Res 2003 Mar;1(5):385-92

Department of Urology, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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March 2003

Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2.

Carcinogenesis 2003 Mar;24(3):483-9

USC/Norris Comprehensive Cancer Center, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033-0800, USA.

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http://dx.doi.org/10.1093/carcin/24.3.483DOI Listing
March 2003

Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.

Hum Genet 2002 Sep 26;111(3):299-302. Epub 2002 Jul 26.

Department of Surgery, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1007/s00439-002-0779-2DOI Listing
September 2002

Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3beta.

J Biol Chem 2002 May 27;277(20):18191-7. Epub 2002 Feb 27.

Department of Orthopedic Surgery, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1074/jbc.M109708200DOI Listing
May 2002