Gerd Heusch

Gerd Heusch

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Gerd Heusch

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Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro-RNA signature in CABG patients.

Acta Anaesthesiol Scand 2019 Apr 11;63(4):483-492. Epub 2018 Dec 11.

Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1111/aas.13296DOI Listing
April 2019

Cardio-oncology - strategies for management of cancer-therapy related cardiovascular disease.

Int J Cardiol 2019 04 11;280:163-175. Epub 2019 Jan 11.

Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, Medical Faculty, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.01.038DOI Listing
April 2019

Attenuation of ST-segment elevation after ischemic conditioning maneuvers reflects cardioprotection online.

Basic Res Cardiol 2019 04 1;114(3):22. Epub 2019 Apr 1.

Institut für Pathophysiologie, Westdeutsches Herz- und Gefäßzentrum, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Germany.

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http://dx.doi.org/10.1007/s00395-019-0732-3DOI Listing
April 2019

Translating Cardioprotection for Patient Benefit: The EU-CARDIOPROTECTION COST Action.

J Am Coll Cardiol 2019 Apr;73(15):2001-2003

Institute for Pathophysiology, West German Heart and Vascular Centre, University of Essen Medical School, Essen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097193395
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http://dx.doi.org/10.1016/j.jacc.2019.03.020DOI Listing
April 2019

Myocardial ischemia - lack of coronary blood flow, myocardial oxygen supply-demand imbalance or what ?

Authors:
Gerd Heusch

Am J Physiol Heart Circ Physiol 2019 Apr 19. Epub 2019 Apr 19.

Institut fur Pathophysiologie, Universitatsklinikum Essen, Germany.

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https://www.physiology.org/doi/10.1152/ajpheart.00139.2019
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http://dx.doi.org/10.1152/ajpheart.00139.2019DOI Listing
April 2019

Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice.

Bone 2019 Apr 24;125:1-7. Epub 2019 Apr 24.

Institute for Pathophysiology, University Hospital Essen, University of Duisburg-Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.04.015DOI Listing
April 2019

Cardioprotection Beyond Infarct Size Reduction.

Circ Res 2019 Mar;124(5):679-680

Department of Cardiology and Vascular Medicine (T.R.), West German Heart and Vascular Center, University of Essen Medical School, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.314679DOI Listing
March 2019

Shahbudin H. Rahimtoola: the scientific legacy.

Authors:
Gerd Heusch

Eur Heart J 2019 Mar;40(11):866

Direktor des Institutes für Pathophysiologie, Universitätsklinikum Essen, Hufelandstr. 55, Essen, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehz076DOI Listing
March 2019

Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection.

Cardiovasc Res 2019 Feb 23. Epub 2019 Feb 23.

Department of Cardiology, Vascular Biology and Metabolism Area, Vall d'Hebron University Hospital and Research Institute (VHIR), Universitat Autónoma de Barcelona, Spain; Instituto CIBER de Enfermedades Cardiovasculares (CIBERCV): Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1093/cvr/cvz053DOI Listing
February 2019

Potent anti-inflammatory properties of HDL in vascular smooth muscle cells mediated by HDL-S1P and their impairment in coronary artery disease due to lower HDL-S1P: a new aspect of HDL dysfunction and its therapy.

FASEB J 2019 Jan 21;33(1):1482-1495. Epub 2018 Aug 21.

Institute for Pathophysiology, West German Heart and Vascular Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1096/fj.201801245RDOI Listing
January 2019

The Spleen in Myocardial Infarction.

Authors:
Gerd Heusch

Circ Res 2019 Jan;124(1):26-28

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314331DOI Listing
January 2019

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week.

J Am Coll Cardiol 2019 Jan;73(1):89-99

IIS-Fundación Jiménez Díaz University Hospital, Madrid, Spain; Department of Cardiology, Vascular Biology and Metabolism Area, Vall d'Hebron University Hospital and Research Institute (VHIR), Barcelona, Spain; Universitat Autónoma de Barcelona, Barcelona, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183906
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http://dx.doi.org/10.1016/j.jacc.2018.09.086DOI Listing
January 2019

The coronary circulation in acute myocardial ischaemia/reperfusion injury - a target for cardioprotection.

Cardiovasc Res 2018 Nov 14. Epub 2018 Nov 14.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1093/cvr/cvy286DOI Listing
November 2018

Vago-Splenic Axis in Signal Transduction of Remote Ischemic Preconditioning in Pigs and Rats.

Circ Res 2018 Oct;123(10):1152-1163

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Germany (H.R.L., P.K., A.S., H.H., G.H.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31385
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http://dx.doi.org/10.1161/CIRCRESAHA.118.313859DOI Listing
October 2018

Cardioprotection research must leave its comfort zone.

Authors:
Gerd Heusch

Eur Heart J 2018 Sep;39(36):3393-3395

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Hufelandstr. 55, Essen, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehy253DOI Listing
September 2018

Translation, Translation, Translation.

Circ Res 2018 Sep;123(8):931-933

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313947DOI Listing
September 2018

Comparison of Lipoprotein(a)-Levels in Patients ≥70 Years of Age With Versus Without Aortic Valve Stenosis.

Am J Cardiol 2018 Aug 11;122(4):645-649. Epub 2018 May 11.

West German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1016/j.amjcard.2018.04.046DOI Listing
August 2018

Lessons Learned From the German Aortic Valve Registry.

J Am Coll Cardiol 2018 Aug;72(6):689-692

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.06.025DOI Listing
August 2018

Humoral transfer and intramyocardial signal transduction of protection by remote ischemic perconditioning in pigs, rats, and mice.

Am J Physiol Heart Circ Physiol 2018 Jul 23;315(1):H159-H172. Epub 2018 Mar 23.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School , Essen , Germany.

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http://dx.doi.org/10.1152/ajpheart.00152.2018DOI Listing
July 2018

Coronary microembolization and microvascular dysfunction.

Int J Cardiol 2018 05 3;258:17-23. Epub 2018 Feb 3.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.02.010DOI Listing
May 2018

Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss.

Nat Med 2018 05 16;24(5):667-678. Epub 2018 Apr 16.

Institute for Pathophysiology, West German Heart and Vascular Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1038/s41591-018-0005-yDOI Listing
May 2018

Reflection of Cardioprotection by Remote Ischemic Perconditioning in Attenuated ST-Segment Elevation During Ongoing Coronary Occlusion in Pigs: Evidence for Cardioprotection From Ischemic Injury.

Circ Res 2018 Apr 21;122(8):1102-1108. Epub 2018 Feb 21.

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.312784DOI Listing
April 2018

EURO-CRIPS: Another piece of evidence for systemic cardiovascular protection by remote ischemic conditioning.

Authors:
Gerd Heusch

Int J Cardiol 2018 04;257:30-31

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.12.043DOI Listing
April 2018

Fatal attraction - A brief pathophysiology of the interaction between atrial fibrillation and myocardial ischemia.

Int J Cardiol 2018 03 6;254:132-135. Epub 2017 Dec 6.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.11.119DOI Listing
March 2018

25 years of remote ischemic conditioning: from laboratory curiosity to clinical outcome.

Authors:
Gerd Heusch

Basic Res Cardiol 2018 03 7;113(3):15. Epub 2018 Mar 7.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1007/s00395-018-0673-2DOI Listing
March 2018

Guideline-adherence regarding critical time intervals in the German Chest Pain Unit registry.

Eur Heart J Acute Cardiovasc Care 2018 Mar 1:2048872618762639. Epub 2018 Mar 1.

1 Department of Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1177/2048872618762639DOI Listing
March 2018

Protection of the human coronary circulation by remote ischemic conditioning.

Authors:
Gerd Heusch

Int J Cardiol 2018 02;252:35-36

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Hufelandstr. 55, 45122 Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.11.044DOI Listing
February 2018

STAT3 as a common signal of ischemic conditioning: a lesson on "rigor and reproducibility" in preclinical studies on cardioprotection.

Basic Res Cardiol 2018 01 20;113(1). Epub 2017 Nov 20.

Institute for Pathophysiology, West German Heart and Vascular Center, Medical School, University of Essen, Hufelandstr. 55, 45122, Essen, Germany.

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http://dx.doi.org/10.1007/s00395-017-0660-zDOI Listing
January 2018

Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasis.

Blood 2017 12 6;130(25):2786-2798. Epub 2017 Nov 6.

Institute for Pathophysiology, West German Heart and Vascular Center and.

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http://dx.doi.org/10.1182/blood-2017-03-774356DOI Listing
December 2017

Cardioprotection Is Alive But Remains Enigmatic: The Nitric Oxide-Protein Kinases-Mitochondria Signaling Axis.

Authors:
Gerd Heusch

Circulation 2017 12;136(24):2356-2358

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.031978DOI Listing
December 2017

Impact of electrical defibrillation on infarct size and no-reflow in pigs subjected to myocardial ischemia-reperfusion without and with ischemic conditioning.

Am J Physiol Heart Circ Physiol 2017 Nov 4;313(5):H871-H878. Epub 2017 Aug 4.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany; and

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http://dx.doi.org/10.1152/ajpheart.00293.2017DOI Listing
November 2017

Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularization.

Sci Rep 2017 10 4;7(1):12660. Epub 2017 Oct 4.

Institute for Pathophysiology, West German Heart and Vascular Center Essen, Universitätsklinikum Essen, Universität Duisburg- Essen, Essen, Germany.

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http://dx.doi.org/10.1038/s41598-017-12833-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627278PMC
October 2017

Melatonin as a cardioprotective therapy following ST-segment elevation myocardial infarction: is it really promising? Reply.

Cardiovasc Res 2017 09;113(11):1418-1419

The Hatter Cardiovascular Institute, University College London, London, UK; The National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, Singapore; and National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore; Department of Cardiology, Vall d'Hebron University Hospital and Research Institute. Universitat Autònoma, Barcelona, Spain; Department of Cardiology, Aarhus University Hospital Skejby, DK-8200, Aarhus N, Denmark; The Hatter Cardiovascular Institute, University College London, London, UK; Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, USA; Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; Duke University, Durham, NC, USA; Department of Medicine, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Faculty of Health Sciences, University of Cape Town, Chris Barnard Building, Anzio Road, Observatory, 7925, Cape Town, Western Cape, South Africa; Tamman Cardiovascular Research Institute, Sheba Medical Center, Tel Hashomer, Israel; Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Tel Hashomer, Israel; Sheba Center for Regenerative Medicine, Stem Cell, and Tissue Engineering, Tel Hashomer, Israel; Institute of Cardiology and Center of Excellence on Aging, 'G. d'Annunzio' University - Chieti, Italy; Texas Heart Institute and University of Texas Medical School in Houston, Department of Internal Medicine, Houston, TX, USA; Explorations Fonctionnelles Cardiovasculaires, Hôpital Louis Pradel, Lyon, France UMR 1060 (CarMeN), Université Claude Bernard, Lyon, France; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy; University of Angers, University Hospital of Angers, Department of Cardiology, Angers, France; Institute of Physiology, Justus-Liebig University of Giessen, Giessen, Germany; Cardiology and UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, the Netherlands; University Medical Center Utrecht, Division Heart and Lungs, and Hubrecht Institute, Utrecht, the Netherlands; Division of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, GA, USA; The Hatter Cardiovascular Institute, University College London, London, UK; and The National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK; Cardiovascular Research Group, Department of Medical Biology, UiT, The Arctic University of Norway, Tromsø, Norway; Institute for Pathophysiology, West-German Heart and Vascular Center, University Hospital Essen, Essen, Germany; Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; and Pharmahungary Group, Szeged, Hungary.

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http://dx.doi.org/10.1093/cvr/cvx137DOI Listing
September 2017

Vagal Cardioprotection in Reperfused Acute Myocardial Infarction.

Authors:
Gerd Heusch

JACC Cardiovasc Interv 2017 08;10(15):1521-1522

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2017.05.063DOI Listing
August 2017

Cardiovascular Research in Germany.

Circ Res 2017 08;121(5):492-495

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School (G.H.); University Medical Center Hamburg Eppendorf, Germany (T.E.); German Centre for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck (T.E.); Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, University Frankfurt, Germany (S.D.); and German Centre for Cardiovascular Research (DZHK), partner site Rhine-Main (S.D.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311132DOI Listing
August 2017

Improving the outcome of primary PCI: protection from reperfusion injury.

Authors:
Gerd Heusch

Cardiovasc Res 2017 08;113(10):e33-e34

Institute for Pathophysiology, West German Heart and Vascular Center, University School of Medicine Essen, Hufelandstr. 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1093/cvr/cvx120DOI Listing
August 2017

Remote Ischemic Conditioning in Cardiovascular Surgery.

Authors:
Gerd Heusch

J Cardiovasc Pharmacol Ther 2017 07 10;22(4):297-301. Epub 2017 Jan 10.

1 Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1177/1074248416687874DOI Listing
July 2017

There Is More to β-Blockade Than Just Blockade of β-Receptors: A Case for Cardioprotective Cross-Signaling.

Authors:
Gerd Heusch

J Am Coll Cardiol 2017 Jul;70(2):193-195

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.05.017DOI Listing
July 2017

Erratum to: Cardioprotection by remote ischemic conditioning and its signal transduction.

Pflugers Arch 2017 Jun;469(5-6):843

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Hufelandstr. 55, 45122, Essen, Germany.

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http://dx.doi.org/10.1007/s00424-017-1936-8DOI Listing
June 2017

Chest Pain Unit Network in Germany: Its Effect on Patients With Acute Coronary Syndromes.

J Am Coll Cardiol 2017 05;69(19):2459-2460

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1016/j.jacc.2017.03.562DOI Listing
May 2017

Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations.

Eur Heart J 2017 04;38(13):935-941

Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma, Pg Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1093/eurheartj/ehw145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381598PMC
April 2017

Critical Issues for the Translation of Cardioprotection.

Authors:
Gerd Heusch

Circ Res 2017 Apr;120(9):1477-1486

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310820DOI Listing
April 2017

The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge.

Eur Heart J 2017 Mar;38(11):774-784

Division of Cardiovascular Diseases, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1093/eurheartj/ehw224DOI Listing
March 2017

lschemic preconditioning in pigs: a causal role for signal transducer and activator of transcription 3.

Am J Physiol Heart Circ Physiol 2017 Mar 30;312(3):H478-H484. Epub 2016 Dec 30.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen, Medical School, Essen, Germany

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http://dx.doi.org/10.1152/ajpheart.00749.2016DOI Listing
March 2017

Cardiomyocyte mitochondria as targets of humoral factors released by remote ischemic preconditioning.

Arch Med Sci 2017 Mar 16;13(2):448-458. Epub 2016 Aug 16.

Institute for Pathophysiology, West German Heart and Vascular Centre Essen, University of Essen, Medical School, Essen, Germany.

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http://dx.doi.org/10.5114/aoms.2016.61789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332452PMC
March 2017

Cardioprotection by remote ischemic conditioning and its signal transduction.

Pflugers Arch 2017 02 7;469(2):159-181. Epub 2016 Dec 7.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Hufelandstr. 55, 45122, Essen, Germany.

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http://dx.doi.org/10.1007/s00424-016-1922-6DOI Listing
February 2017

Remote ischemic conditioning: the enigmatic transfer of protection.

Authors:
Gerd Heusch

Cardiovasc Res 2017 01;113(1):1-2

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Hufelandstr. 55, 45122 Essen, Germany

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http://dx.doi.org/10.1093/cvr/cvw240DOI Listing
January 2017

Quantification and characterisation of released plaque material during bioresorbable vascular scaffold implantation into right coronary artery lesions by multimodality intracoronary imaging.

EuroIntervention 2016 Dec;12(12):1481-1489

Institute for Pathophysiology, West German Heart and Vascular Center Essen, University of Essen Medical School, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.4244/EIJ-D-15-00207DOI Listing
December 2016

Influence of stent implantation on erythrocyte aggregation in human native coronary arteries and saphenous vein grafts.

Microcirculation 2016 11;23(8):637-645

Institute for Pathophysiology, West German Heart and Vascular Centre Essen, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1111/micc.12326DOI Listing
November 2016

Confounders of Cardioprotection by Remote Ischemic Preconditioning in Patients Undergoing Coronary Artery Bypass Grafting.

Cardiology 2016 5;133(2):128-33. Epub 2015 Nov 5.

Institute for Pathophysiology, West German Heart and Vascular Center Essen, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1159/000441216DOI Listing
September 2016

Time to Give Up on Cardioprotection? A Critical Appraisal of Clinical Studies on Ischemic Pre-, Post-, and Remote Conditioning.

Circ Res 2016 Aug;119(5):676-95

From the Institute for Pathophysiology (G.H.) and Clinic for Cardiology (T.R.), West German Heart and Vascular Center, University School of Medicine Essen, Essen, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308736DOI Listing
August 2016

Resting heart rate is an independent predictor of all-cause mortality in the middle aged general population.

Clin Res Cardiol 2016 Jul 23;105(7):601-12. Epub 2016 Jan 23.

Clinic of Cardiology, West-German Heart and Vascular Center Essen, University Clinic Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00392-015-0956-7DOI Listing
July 2016

Ivabradine in chronic stable angina: Effects by and beyond heart rate reduction.

Int J Cardiol 2016 Jul 11;215:1-6. Epub 2016 Apr 11.

Institute for Pathophysiology, West German Heart and Vascular Centre Essen, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2016.04.001DOI Listing
July 2016

Myocardial Ischemia: Lack of Coronary Blood Flow or Myocardial Oxygen Supply/Demand Imbalance?

Authors:
Gerd Heusch

Circ Res 2016 Jul;119(2):194-6

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308925DOI Listing
July 2016

Ivabradine: Cardioprotection By and Beyond Heart Rate Reduction.

Drugs 2016 May;76(7):733-40

West German Heart and Vascular Center, Institute for Pathophysiology, University of Essen Medical School, Hufelandstr. 55, 45122, Essen, Germany.

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http://link.springer.com/content/pdf/10.1007%2Fs40265-016-05
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http://link.springer.com/10.1007/s40265-016-0567-2
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http://dx.doi.org/10.1007/s40265-016-0567-2DOI Listing
May 2016

The Coronary Circulation as a Target of Cardioprotection.

Authors:
Gerd Heusch

Circ Res 2016 05;118(10):1643-58

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, University of Essen, Essen, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308640DOI Listing
May 2016

Cardiac Computed Tomography in Certified German Chest Pain Units.

Crit Pathw Cardiol 2016 Mar;15(1):11-5

From the *Department of Cardiology, Arnsberg Medical Center, Arnsberg, Germany; †Institute for Myocardial Infarction Research, Ludwigshafen, Germany; ‡CCB, Cardioangiologisches Centrum Bethanien, Frankfurt am Main, Germany; §Medical Clinic I, Städtische Kliniken Neuss, Lukaskrankenhaus GmbH, Neuss, Germany; ¶Clinic for Cardiology and Angiology, Municipal Hospital Karlsruhe, Karlsruhe, Germany; ‖2nd Department of Medicine, Johannes Gutenberg-University Mainz, Mainz, Germany; **3rd Department of Medicine, University Hospital Heidelberg, Heidelberg, Germany; ††Department of Cardiology, Pneumology, Internal Intensive Care Medicine, Klinikum Neuperlach, Städtisches Klinikum München GmbH, Munich, Germany; ‡‡Institute for Pathophysiology, West German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany; §§2nd Department of Medicine, Westpfalz-Klinikum, Kaiserslautern, Germany; ¶¶Department of Cardiology, Herz- und Gefäß-Klinik GmbH, Bad Neustadt a. d. Saale, Germany; ‖‖University of Leipzig, Heart Center, Leipzig, Germany; ***Department of Cardiology, Catholic Clinics Essen-Northwest, Essen, Germany; and †††2nd Department of Medicine, HELIOS Kreiskrankenhaus Gotha/Ohrdruf, Gotha, Germany.

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http://dx.doi.org/10.1097/HPC.0000000000000061DOI Listing
March 2016

Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in Mice.

J Immunol 2016 Feb 22;196(4):1655-65. Epub 2016 Jan 22.

Institute for Pathophysiology, West German Heart and Vascular Center, University Hospital Essen, 45122 Essen, Germany;

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http://dx.doi.org/10.4049/jimmunol.1500897DOI Listing
February 2016

Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning.

JACC Basic Transl Sci 2016 Jan-Feb;1(1-2):3-13. Epub 2016 Feb 13.

Institute for Pathophysiology, West-German Heart and Vascular Center Essen, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1016/j.jacbts.2016.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012372PMC
February 2016

ERICCA and RIPHeart: two nails in the coffin for cardioprotection by remote ischemic conditioning? Probably not!

Eur Heart J 2016 Jan 27;37(2):200-2. Epub 2015 Oct 27.

Division of Cardiovascular Diseases, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://eurheartj.oxfordjournals.org/content/ehj/early/2015/1
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http://dx.doi.org/10.1093/eurheartj/ehv606DOI Listing
January 2016

Coronary artery calcification - predictor or player in the no-reflow phenomenon?

Authors:
Gerd Heusch

Coron Artery Dis 2015 Nov;26(7):553-4

Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1097/MCA.0000000000000270DOI Listing
November 2015

CIRCUS: a kiss of death for cardioprotection?

Authors:
Gerd Heusch

Cardiovasc Res 2015 Nov 25;108(2):215-6. Epub 2015 Sep 25.

Institut für Pathophysiologie, Westdeutsches Herz- und Gefäßzentrum Essen, Universitätsklinikum Essen, Hufelandstr. 55, Essen 45122, Germany

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http://dx.doi.org/10.1093/cvr/cvv225DOI Listing
November 2015

Across-Species Transfer of Protection by Remote Ischemic Preconditioning With Species-Specific Myocardial Signal Transduction by Reperfusion Injury Salvage Kinase and Survival Activating Factor Enhancement Pathways.

Circ Res 2015 Jul 9;117(3):279-88. Epub 2015 Jun 9.

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.306878DOI Listing
July 2015

Treatment of Myocardial Ischemia/Reperfusion Injury by Ischemic and Pharmacological Postconditioning.

Authors:
Gerd Heusch

Compr Physiol 2015 Jul;5(3):1123-45

Institut für Pathophysiologie, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1002/cphy.c140075DOI Listing
July 2015

Is MRI Really the Gold Standard for the Quantification of Salvage From Myocardial Infarction?

Circ Res 2015 Jul;117(3):222-4

From the Institut für Diagnostische und Interventionelle Radiologie der Heinrich Heine-Universität Düsseldorf, Düsseldorf, Germany (P.H.); Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie des Universitätsklinikums Essen, Essen, Germany (F.N.); and Institut für Pathophysiologie, Westdeutsches Herz- und Gefässzentrum, Universitätsklinikum Essen, Essen, Germany (G.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.306929DOI Listing
July 2015

Chest Pain Centers: A Comparison of Accreditation Programs in Germany and the United States.

Crit Pathw Cardiol 2015 Jun;14(2):67-73

From the *Department of Cardiology, Arnsberg Medical Center, Arnsberg, Germany; †Department of Emergency Medicine, University of Virginia, Charlottesville, VA; ‡Society of Cardiovascular Patient Care, Dublin, OH; §Department of Cardiology, West German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany; ¶Institute for Pathophysiology, West German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany; ‖Institute for Myocardial Infarction Research Foundation Ludwigshafen, University of Heidelberg, Heidelberg, Germany; and **Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC.

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http://dx.doi.org/10.1097/HPC.0000000000000041DOI Listing
June 2015