Gerardo García-Díaz Barriga

Gerardo García-Díaz Barriga

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Gerardo García-Díaz Barriga

Gerardo García-Díaz Barriga

Publications by authors named "Gerardo García-Díaz Barriga"

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Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis.

J Control Release 2020 Jan 2;319:262-275. Epub 2020 Jan 2.

Laboratory for General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, 9000 Ghent, Belgium; Center for Advanced Light Microscopy, Ghent University, 9000 Ghent, Belgium; Université de Lille, IEMN, UMR 8520, Lab. Phys. Lasers Atomes & Mol., UMR 8523, 59869 Villeneuve d'Ascq, France. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.12.050DOI Listing
January 2020

Increased translation as a novel pathogenic mechanism in Huntington's disease.

Brain 2019 Oct;142(10):3158-3175

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, Barcelona, Catalonia.

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http://dx.doi.org/10.1093/brain/awz230DOI Listing
October 2019

Early Downregulation of p75 by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice.

Mol Neurobiol 2019 Feb 27;56(2):935-953. Epub 2018 May 27.

Departament de Biomedicina, Facultat de Medicina, Institut de Neurosciències, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12035-018-1126-5DOI Listing
February 2019

A FBN1 3'UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome.

Biochim Biophys Acta Mol Basis Dis 2019 01 30;1865(1):107-114. Epub 2018 Oct 30.

Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Barcelona, Barcelona 08036, Spain; Institute of Biomedical Investigation August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain; Institute of Nanoscience and Nanotechnology IN2UB, University of Barcelona, 08036 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.10.029DOI Listing
January 2019

Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease.

Neurobiol Dis 2018 12 31;120:88-97. Epub 2018 Aug 31.

Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.08.024DOI Listing
December 2018

RNA-Seq transcriptomic profiling of primary murine microglia treated with LPS or LPS + IFNγ.

Sci Rep 2018 10 31;8(1):16096. Epub 2018 Oct 31.

Department of Biomedical Sciences, Biochemistry and Molecular Biology Unit, School of Medicine, University of Barcelona, IDIBAPS, Barcelona, Spain.

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http://www.nature.com/articles/s41598-018-34412-9
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http://dx.doi.org/10.1038/s41598-018-34412-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208373PMC
October 2018

Huntington's disease: novel therapeutic perspectives hanging in the balance.

Expert Opin Ther Targets 2018 05 26;22(5):385-399. Epub 2018 Apr 26.

a Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències , Universitat de Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/14728222.2018.1465930DOI Listing
May 2018

7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway.

Hum Mol Genet 2017 08;26(16):3144-3160

Departament de Biomedicina, Facultat de Medicina, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/hmg/ddx198DOI Listing
August 2017

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons.

Development 2017 04 13;144(8):1566-1577. Epub 2017 Mar 13.

Stem Cells and Regenerative Medicine Laboratory, Production and Validation Center of Advanced Therapies (Creatio), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain

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http://dx.doi.org/10.1242/dev.138248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399659PMC
April 2017

Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity.

Neurobiol Dis 2016 Nov 11;95:22-34. Epub 2015 Sep 11.

Departament de Biologia Cel·lular, Immunologia i Neurociències, Facultat de Medicina, Universitat de Barcelona, Casanova, 143, 08036 Barcelona, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Casanova, 143, 08036 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.09.001DOI Listing
November 2016

Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation.

Hum Mol Genet 2015 Sep 10;24(17):4958-70. Epub 2015 Jun 10.

Departament de Biologia Cel·lular, Immunologia i Neurociències, Facultat de Medicina, Universitat de Barcelona, 08036 Barcelona, Spain, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain

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http://dx.doi.org/10.1093/hmg/ddv218DOI Listing
September 2015

Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons.

Mol Ther Methods Clin Dev 2015 16;2:15030. Epub 2015 Sep 16.

Department of Cell Biology, Immunology and Neuroscience, Faculty of Medicine, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), and Networked Biomedical Research Centre for NeuroDegenerative Disorders (CIBERNED), University of Barcelona , Barcelona, Spain.

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http://dx.doi.org/10.1038/mtm.2015.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571731PMC
September 2015