Publications by authors named "Gerard H Koppelman"

100Publications

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.

Authors:
Suzanne Vogelezang Jonathan P Bradfield Tarunveer S Ahluwalia John A Curtin Timo A Lakka Niels Grarup Markus Scholz Peter J van der Most Claire Monnereau Evie Stergiakouli Anni Heiskala Momoko Horikoshi Iryna O Fedko Natalia Vilor-Tejedor Diana L Cousminer Marie Standl Carol A Wang Jorma Viikari Frank Geller Carmen Íñiguez Niina Pitkänen Alessandra Chesi Jonas Bacelis Loic Yengo Maties Torrent Ioanna Ntalla Øyvind Helgeland Saskia Selzam Judith M Vonk Mohammed H Zafarmand Barbara Heude Ismaa Sadaf Farooqi Akram Alyass Robin N Beaumont Christian T Have Peter Rzehak Jose Ramon Bilbao Theresia M Schnurr Inês Barroso Klaus Bønnelykke Lawrence J Beilin Lisbeth Carstensen Marie-Aline Charles Bo Chawes Karine Clément Ricardo Closa-Monasterolo Adnan Custovic Johan G Eriksson Joaquin Escribano Maria Groen-Blokhuis Veit Grote Dariusz Gruszfeld Hakon Hakonarson Torben Hansen Andrew T Hattersley Mette Hollensted Jouke-Jan Hottenga Elina Hyppönen Stefan Johansson Raimo Joro Mika Kähönen Ville Karhunen Wieland Kiess Bridget A Knight Berthold Koletzko Andreas Kühnapfel Kathrin Landgraf Jean-Paul Langhendries Terho Lehtimäki Jaakko T Leinonen Aihuali Li Virpi Lindi Estelle Lowry Mariona Bustamante Carolina Medina-Gomez Mads Melbye Kim F Michaelsen Camilla S Morgen Trevor A Mori Tenna R H Nielsen Harri Niinikoski Albertine J Oldehinkel Katja Pahkala Kalliope Panoutsopoulou Oluf Pedersen Craig E Pennell Christine Power Sijmen A Reijneveld Fernando Rivadeneira Angela Simpson Peter D Sly Jakob Stokholm Kook K Teo Elisabeth Thiering Nicholas J Timpson André G Uitterlinden Catharina E M van Beijsterveldt Barbera D C van Schaik Marc Vaudel Elvira Verduci Rebecca K Vinding Mandy Vogel Eleftheria Zeggini Sylvain Sebert Mads V Lind Christopher D Brown Loreto Santa-Marina Eva Reischl Christine Frithioff-Bøjsøe David Meyre Eleanor Wheeler Ken Ong Ellen A Nohr Tanja G M Vrijkotte Gerard H Koppelman Robert Plomin Pål R Njølstad George D Dedoussis Philippe Froguel Thorkild I A Sørensen Bo Jacobsson Rachel M Freathy Babette S Zemel Olli Raitakari Martine Vrijheid Bjarke Feenstra Leo-Pekka Lyytikäinen Harold Snieder Holger Kirsten Patrick G Holt Joachim Heinrich Elisabeth Widén Jordi Sunyer Dorret I Boomsma Marjo-Riitta Järvelin Antje Körner George Davey Smith Jens-Christian Holm Mustafa Atalay Clare Murray Hans Bisgaard Mark I McCarthy Vincent W V Jaddoe Struan F A Grant Janine F Felix

PLoS Genet 2020 Oct 12;16(10):e1008718. Epub 2020 Oct 12.

The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1008718DOI Listing
October 2020

Air pollution and IgE sensitization in 4 European birth cohorts-the MeDALL project.

J Allergy Clin Immunol 2020 Sep 11. Epub 2020 Sep 11.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.08.030DOI Listing
September 2020

The genetics of asthma and the promise of genomics-guided drug target discovery.

Lancet Respir Med 2020 10 7;8(10):1045-1056. Epub 2020 Sep 7.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(20)30363-5DOI Listing
October 2020

House dust endotoxin, asthma and allergic sensitization through childhood into adolescence.

Clin Exp Allergy 2020 Sep 23;50(9):1055-1064. Epub 2020 Jul 23.

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/cea.13705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540017PMC
September 2020

On Genetics, Lung Developmental Biology, and Adult Lung Function.

Am J Respir Crit Care Med 2020 Sep;202(6):791-793

Asthma and Airway Disease Research Center University of Arizona Tucson, Arizona and.

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http://dx.doi.org/10.1164/rccm.202006-2123EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491403PMC
September 2020

Differences in lung clearance index and functional residual capacity between two commercial multiple-breath nitrogen washout devices in healthy children and adults.

ERJ Open Res 2020 Apr 29;6(2). Epub 2020 Jun 29.

University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Dept of Paediatric Pulmonology and Paediatric Allergy, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/23120541.00247-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322914PMC
April 2020

Likely questionnaire-diagnosed food allergy in 78, 890 adults from the northern Netherlands.

PLoS One 2020 13;15(5):e0231818. Epub 2020 May 13.

Department of Paediatric Pulmonology and Paediatric Allergy, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231818PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219708PMC
July 2020

A Novel Role for Bronchial MicroRNAs and Long Noncoding RNAs in Asthma Remission.

Am J Respir Crit Care Med 2020 Aug;202(4):614-618

University Medical Center Groningen, University of GroningenGroningen, the Netherlands.

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http://dx.doi.org/10.1164/rccm.201908-1610LEDOI Listing
August 2020

Maternal Allergy and the Presence of Nonhuman Proteinaceous Molecules in Human Milk.

Nutrients 2020 Apr 22;12(4). Epub 2020 Apr 22.

Food Quality and Design Group, Wageningen University & Research, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.

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http://dx.doi.org/10.3390/nu12041169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230597PMC
April 2020

Air pollution and the development of asthma from birth until young adulthood.

Eur Respir J 2020 Jul 2;56(1). Epub 2020 Jul 2.

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1183/13993003.00147-2020DOI Listing
July 2020

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

Genome Med 2020 03 2;12(1):25. Epub 2020 Mar 2.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13073-020-0716-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050134PMC
March 2020

Eradication of in cystic fibrosis patients with inhalation of dry powder tobramycin.

Ther Adv Respir Dis 2020 Jan-Dec;14:1753466620905279

Department of Pulmonary Diseases and Tuberculosis, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1177/1753466620905279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016310PMC
February 2020

Nasal DNA methylation profiling of asthma and rhinitis.

J Allergy Clin Immunol 2020 Jun 14;145(6):1655-1663. Epub 2020 Jan 14.

Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Gronigen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.12.911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282965PMC
June 2020

IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids.

Allergy 2020 04 17;75(4):984-989. Epub 2019 Dec 17.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/all.14125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176513PMC
April 2020

Timing of secondhand smoke, pet, dampness or mould exposure and lung function in adolescence.

Thorax 2020 02 20;75(2):153-163. Epub 2019 Nov 20.

Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands

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http://dx.doi.org/10.1136/thoraxjnl-2019-213149DOI Listing
February 2020

The role of epigenetics in the development of childhood asthma.

Expert Rev Clin Immunol 2019 12 10;15(12):1287-1302. Epub 2019 Nov 10.

Dept. of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1080/1744666X.2020.1686977DOI Listing
December 2019

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.

Epigenomics 2019 10 19;11(13):1487-1500. Epub 2019 Sep 19.

Department of Health & Human Services, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.2217/epi-2019-0066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836223PMC
October 2019

Role of timing of exposure to pets and dampness or mould on asthma and sensitization in adolescence.

Clin Exp Allergy 2019 10 18;49(10):1352-1361. Epub 2019 Aug 18.

Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/cea.13471DOI Listing
October 2019

Genetic risk scores do not improve asthma prediction in childhood.

J Allergy Clin Immunol 2019 09 27;144(3):857-860.e7. Epub 2019 May 27.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.05.017DOI Listing
September 2019

Use of cleaning agents at home and respiratory and allergic symptoms in adolescents: The PIAMA birth cohort study.

Environ Int 2019 07 25;128:63-69. Epub 2019 Apr 25.

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2019.03.049DOI Listing
July 2019

Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children.

J Expo Sci Environ Epidemiol 2019 06 26;29(4):539-547. Epub 2019 Apr 26.

Channing Division of Network Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1038/s41370-019-0136-3DOI Listing
June 2019

Improvements in air quality: whose lungs benefit?

Eur Respir J 2019 Apr 25;53(4). Epub 2019 Apr 25.

University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Dept of Pediatric Pulmonology and Pediatric Allergology, Groningen, The Netherlands.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00365
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http://dx.doi.org/10.1183/13993003.00365-2019DOI Listing
April 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.

Dev Cell 2019 04 28;49(1):10-29. Epub 2019 Mar 28.

Department of Biomedical Informatics, University of Cincinnati College of Medicine, and Cincinnati Children's Hospital Medical Center, Division of Biomedical Informatics, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.devcel.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616346PMC
April 2019

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

Am J Hum Genet 2019 04 28;104(4):665-684. Epub 2019 Mar 28.

Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm 171 77, Sweden; Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm 171 76, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297193006
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http://dx.doi.org/10.1016/j.ajhg.2019.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451732PMC
April 2019

Applying the CAMP trial asthma remission prediction model to the Dutch asthma remission studies.

J Allergy Clin Immunol 2019 05 12;143(5):1973-1975. Epub 2019 Mar 12.

Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.040DOI Listing
May 2019

Does breast milk adiponectin affect BMI and cardio-metabolic markers in childhood?

Br J Nutr 2019 04 7;121(8):905-913. Epub 2019 Feb 7.

5Center for Nutrition, Prevention, and Health Services,National Institute for Public Health and the Environment,3720 BA Bilthoven,The Netherlands.

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http://dx.doi.org/10.1017/S0007114519000266DOI Listing
April 2019

Precision medicine in childhood asthma.

Curr Opin Allergy Clin Immunol 2019 04;19(2):141-147

Department of Pediatrics, Division of Respiratory Medicine and Allergology, Erasmus MC - Sophia, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/ACI.0000000000000517DOI Listing
April 2019

DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study.

Lancet Respir Med 2019 04 21;7(4):336-346. Epub 2018 Dec 21.

Division of Pulmonary Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132600183046
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http://dx.doi.org/10.1016/S2213-2600(18)30466-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441380PMC
April 2019

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

J Allergy Clin Immunol 2019 06 21;143(6):2062-2074. Epub 2018 Dec 21.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183278
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http://dx.doi.org/10.1016/j.jaci.2018.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556405PMC
June 2019

Associations of residential exposure to agricultural pesticides with asthma prevalence in adolescence: The PIAMA birth cohort.

Environ Int 2018 12 25;121(Pt 1):435-442. Epub 2018 Sep 25.

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01604120183113
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http://dx.doi.org/10.1016/j.envint.2018.09.029DOI Listing
December 2018

Air pollution exposure and lung function until age 16 years: the PIAMA birth cohort study.

Eur Respir J 2018 09 27;52(3). Epub 2018 Sep 27.

Institute for Risk Assessment Sciences (IRAS), Division of Environmental Epidemiology and Veterinary Public Health, Utrecht University, Utrecht, The Netherlands.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00218
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http://dx.doi.org/10.1183/13993003.00218-2018DOI Listing
September 2018

Air pollution and airway resistance at age 8 years - the PIAMA birth cohort study.

Environ Health 2018 07 17;17(1):61. Epub 2018 Jul 17.

Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 80178, 3508TD, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s12940-018-0407-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050657PMC
July 2018

Pharmacogenetics of inhaled long-acting beta2-agonists in asthma: A systematic review.

Pediatr Allergy Immunol 2018 11 12;29(7):705-714. Epub 2018 Aug 12.

Department of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/pai.12956DOI Listing
November 2018

Greater severity of peanut challenge reactions using a high-fat vs low-fat matrix vehicle.

Clin Exp Allergy 2018 10 26;48(10):1364-1367. Epub 2018 Jul 26.

Department of Pediatric Pulmonology and Pediatric Allergy, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/cea.13210DOI Listing
October 2018

Response to letters to the editor regarding our paper "Early introduction of complementary foods and childhood overweight in breastfed and formula-fed infants in the Netherlands: the PIAMA birth cohort study".

Eur J Nutr 2018 Aug;57(5):1999-2000

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, STR 6.131, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00394-018-1701-6DOI Listing
August 2018

What do we need to transfer pharmacogenetics findings into the clinic?

Pharmacogenomics 2018 05 27;19(7):589-592. Epub 2018 Apr 27.

Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, P.O. Box 22700, NL-1100 DE Amsterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs-2018-0026DOI Listing
May 2018

Nasal epithelium as a proxy for bronchial epithelium for smoking-induced gene expression and expression Quantitative Trait Loci.

J Allergy Clin Immunol 2018 07 6;142(1):314-317.e15. Epub 2018 Mar 6.

Department of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands; GRIAC (Groningen Research Institute for Asthma and COPD), Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands; Department of Pathology & Medical Biology, Section of Medical Biology, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2018.01.047DOI Listing
July 2018

Genetic regulation of methylation and IL1RL1-a protein levels in asthma.

Eur Respir J 2018 03 8;51(3). Epub 2018 Mar 8.

Dept of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01377-2017DOI Listing
March 2018

Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study.

Twin Res Hum Genet 2018 04 6;21(2):89-100. Epub 2018 Mar 6.

Department of Epidemiology,University Medical Center Groningen,University of Groningen,Groningen,The Netherlands.

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http://dx.doi.org/10.1017/thg.2018.6DOI Listing
April 2018

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Lancet Respir Med 2018 05 26;6(5):379-388. Epub 2018 Feb 26.

GRIAC research institute Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30052-3DOI Listing
May 2018

Early introduction of complementary foods and childhood overweight in breastfed and formula-fed infants in the Netherlands: the PIAMA birth cohort study.

Eur J Nutr 2018 Aug 22;57(5):1985-1993. Epub 2018 Feb 22.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, STR 6.131, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00394-018-1639-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060808PMC
August 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts.

J Allergy Clin Immunol 2018 03 10;141(3):964-971. Epub 2017 Nov 10.

Skin Research Group, School of Medicine, University of Dundee, Dundee, United Kingdom; Department of Dermatology, Ninewells Hospital, Dundee, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2017.09.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840507PMC
March 2018

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.

Authors:
Janine F Felix Bonnie R Joubert Andrea A Baccarelli Gemma C Sharp Catarina Almqvist Isabella Annesi-Maesano Hasan Arshad Nour Baïz Marian J Bakermans-Kranenburg Kelly M Bakulski Elisabeth B Binder Luigi Bouchard Carrie V Breton Bert Brunekreef Kelly J Brunst Esteban G Burchard Mariona Bustamante Leda Chatzi Monica Cheng Munthe-Kaas Eva Corpeleijn Darina Czamara Dana Dabelea George Davey Smith Patrick De Boever Liesbeth Duijts Terence Dwyer Celeste Eng Brenda Eskenazi Todd M Everson Fahimeh Falahi M Daniele Fallin Sara Farchi Mariana F Fernandez Lu Gao Tom R Gaunt Akram Ghantous Matthew W Gillman Semira Gonseth Veit Grote Olena Gruzieva Siri E Håberg Zdenko Herceg Marie-France Hivert Nina Holland John W Holloway Cathrine Hoyo Donglei Hu Rae-Chi Huang Karen Huen Marjo-Riitta Järvelin Dereje D Jima Allan C Just Margaret R Karagas Robert Karlsson Wilfried Karmaus Katerina J Kechris Juha Kere Manolis Kogevinas Berthold Koletzko Gerard H Koppelman Leanne K Küpers Christine Ladd-Acosta Jari Lahti Nathalie Lambrechts Sabine A S Langie Rolv T Lie Andrew H Liu Maria C Magnus Per Magnus Rachel L Maguire Carmen J Marsit Wendy McArdle Erik Melén Phillip Melton Susan K Murphy Tim S Nawrot Lorenza Nisticò Ellen A Nohr Björn Nordlund Wenche Nystad Sam S Oh Emily Oken Christian M Page Patrice Perron Göran Pershagen Costanza Pizzi Michelle Plusquin Katri Raikkonen Sarah E Reese Eva Reischl Lorenzo Richiardi Susan Ring Ritu P Roy Peter Rzehak Greet Schoeters David A Schwartz Sylvain Sebert Harold Snieder Thorkild I A Sørensen Anne P Starling Jordi Sunyer Jack A Taylor Henning Tiemeier Vilhelmina Ullemar Marina Vafeiadi Marinus H Van Ijzendoorn Judith M Vonk Annette Vriens Martine Vrijheid Pei Wang Joseph L Wiemels Allen J Wilcox Rosalind J Wright Cheng-Jian Xu Zongli Xu Ivana V Yang Paul Yousefi Hongmei Zhang Weiming Zhang Shanshan Zhao Golareh Agha Caroline L Relton Vincent W V Jaddoe Stephanie J London

Int J Epidemiol 2018 02;47(1):22-23u

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, USA.

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http://dx.doi.org/10.1093/ije/dyx190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837319PMC
February 2018

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Hum Mol Genet 2017 10;26(20):4067-4085

MRC Integrative Epidemiology Unit.

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http://dx.doi.org/10.1093/hmg/ddx290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656174PMC
October 2017

Genetic and epigenetic regulation of YKL-40 in childhood.

J Allergy Clin Immunol 2018 03 21;141(3):1105-1114. Epub 2017 Jul 21.

Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2017.06.030DOI Listing
March 2018

Childhood factors associated with complete and clinical asthma remission at 25 and 49 years.

Eur Respir J 2017 06 8;49(6). Epub 2017 Jun 8.

University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01974-2016DOI Listing
June 2017

Respiratory function after esophageal replacement in children.

J Pediatr Surg 2017 Nov 21;52(11):1736-1741. Epub 2017 Mar 21.

Academic Medical Center Amsterdam, Pediatric Surgery, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.jpedsurg.2017.03.046DOI Listing
November 2017

Apolipoprotein B: a possible new biomarker for anaphylaxis.

Ann Allergy Asthma Immunol 2017 Apr 6;118(4):515-516. Epub 2017 Mar 6.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1016/j.anai.2017.01.021DOI Listing
April 2017

Data-driven Asthma Phenotypes in Childhood. Does the Environment Hold the Clue?

Am J Respir Crit Care Med 2017 03;195(5):545-546

2 Institute for Risk Assessment Sciences Utrecht University Utrecht, the Netherlands and.

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http://dx.doi.org/10.1164/rccm.201610-1982EDDOI Listing
March 2017

The need for precision medicine clinical trials in childhood asthma: rationale and design of the PUFFIN trial.

Pharmacogenomics 2017 Mar 22;18(4):393-401. Epub 2017 Feb 22.

Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs-2016-0174DOI Listing
March 2017

Lifetime secondhand smoke exposure and childhood and adolescent asthma: findings from the PIAMA cohort.

Environ Health 2017 02 23;16(1):14. Epub 2017 Feb 23.

Institute for Risk Assessment Sciences (IRAS), Division of Environmental Epidemiology, Utrecht University, P.O. Box 80178, 3508 TD, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s12940-017-0223-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324208PMC
February 2017

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes.

J Allergy Clin Immunol 2017 02;139(2):388-399

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2016.12.940DOI Listing
February 2017

Health-Related Factors Associated with Discrepancies between Children's Potential and Attained Secondary School Level: A Longitudinal Study.

PLoS One 2016 22;11(12):e0168110. Epub 2016 Dec 22.

Centre for Nutrition, Prevention and health Services, National Institute for Public Health and the Environment, BA Bilthoven, Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168110PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179065PMC
July 2017

Asthma diagnosis in a child and cessation of smoking in the child's home: the PIAMA birth cohort.

J Expo Sci Environ Epidemiol 2017 09 14;27(5):521-525. Epub 2016 Dec 14.

Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/jes.2016.75DOI Listing
September 2017

Pharmacogenetics of asthma: toward precision medicine.

Curr Opin Pulm Med 2017 01;23(1):12-20

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen; GRIAC Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1097/MCP.0000000000000335DOI Listing
January 2017

TRPA1 gene polymorphisms and childhood asthma.

Pediatr Allergy Immunol 2017 03 8;28(2):191-198. Epub 2016 Dec 8.

Centre for Primary Care and Public Health, Barts and The London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1111/pai.12673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324656PMC
March 2017

Concerns with beta2-agonists in pediatric asthma - a clinical perspective.

Paediatr Respir Rev 2017 Jan 16;21:80-85. Epub 2016 Jun 16.

Department of Pediatrics, Medisch Spectrum Twente, 7512 KZ Enschede, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.prrv.2016.05.006DOI Listing
January 2017