Gerard A Rongen

Gerard A Rongen

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Gerard A Rongen

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Effect of two dosages of sodium chloride intake on the blood pressure response to caffeinated coffee in humans .

Int J Food Sci Nutr 2019 Dec 10;70(8):1014-1019. Epub 2019 Apr 10.

Department of Internal Medicine, Radboud University Medical Center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.1080/09637486.2019.1595541DOI Listing
December 2019

The European Association for Clinical Pharmacology and Therapeutics-25 years' young and going strong.

Eur J Clin Pharmacol 2019 Jun 16;75(6):743-750. Epub 2019 May 16.

Department of Medical and Health Sciences, Division of Drug Research, Linköping University, SE-581 85, Linköping, Sweden.

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http://dx.doi.org/10.1007/s00228-019-02690-5DOI Listing
June 2019

Crystal-proven Gout and Characteristic Gout Severity Factors Are Associated with Cardiovascular Disease.

J Rheumatol 2018 06 15;45(6):858-863. Epub 2018 Apr 15.

From the Department of Rheumatology, Rijnstate Hospital, Arnhem; Department of Rheumatology, Radboud University Medical Centre; Departments of Internal Medicine, and Pharmacology and Toxicology, Radboud University Medical Centre; Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen; Department of Dermatology, University Medical Centre Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.170555DOI Listing
June 2018

Pharmacogenetic Information in Clinical Guidelines: The European Perspective.

Clin Pharmacol Ther 2018 05 30;103(5):795-801. Epub 2018 Mar 30.

Department of Clinical Pharmacy & Toxicology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/cpt.1049DOI Listing
May 2018

Plasma galectin-3 concentrations in patients with primary aldosteronism.

J Hypertens 2017 09;35(9):1849-1856

aDepartment of Pharmacology and Toxicology bDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen cDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen dDepartment for Health Evidence eDepartment of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/HJH.0000000000001383DOI Listing
September 2017

A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.

Thromb Haemost 2017 08 6;117(9):1798-1807. Epub 2017 Jul 6.

Prof. N. P. Riksen, Dept. of Internal Medicine 463, Radboud University Medical Center, PO Box 9101, 6500HB Nijmegen, The Netherlands, Tel.: +31 24 3618819, Fax: +31 24 3616519, E-mail:

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http://dx.doi.org/10.1160/TH16-10-0799DOI Listing
August 2017

Impact of lifelong exercise training on endothelial ischemia-reperfusion and ischemic preconditioning in humans.

Am J Physiol Regul Integr Comp Physiol 2017 05 15;312(5):R828-R834. Epub 2017 Mar 15.

Radboud Institute for Health Sciences, Department of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands;

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http://dx.doi.org/10.1152/ajpregu.00466.2016DOI Listing
May 2017

Salvia Miltiorrhiza Root Water-Extract (Danshen) Has No Beneficial Effect on Cardiovascular Risk Factors. A Randomized Double-Blind Cross-Over Trial.

PLoS One 2015 20;10(7):e0128695. Epub 2015 Jul 20.

Department of Internal Medicine, Radboud university medical center, Nijmegen, The Netherlands; Department of Pharmacology and Toxicology, Radboud university medical center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128695PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508048PMC
April 2016

Digital Ischemia in a Young Woman after Minor Wrist Trauma-A Rare Diagnosis and an Innovative Multidisciplinary Treatment.

J Vasc Interv Radiol 2016 Apr;27(4):608-11

Interventional Radiology Radboudumc Geert Grooteplein 8 Nijmegen 6525GA, The Netherlands.

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http://dx.doi.org/10.1016/j.jvir.2015.12.023DOI Listing
April 2016

The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study.

PLoS One 2014 30;9(10):e111248. Epub 2014 Oct 30.

Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111248PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214740PMC
December 2015

Impaired endothelium-dependent vasodilation does not initiate the development of sunitinib-associated hypertension.

J Hypertens 2015 Oct;33(10):2075-82

aDepartment of Pharmacology-Toxicology bDepartment of Medical Oncology cDepartment of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/HJH.0000000000000662DOI Listing
October 2015

Sunitinib does not attenuate contractile force following a period of ischemia in isolated human cardiac muscle.

Target Oncol 2015 Sep 23;10(3):439-43. Epub 2014 Dec 23.

Department of Pharmacology-Toxicology, Radboud University Medical Center, PO BOX 9101, 6500 HB, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1007/s11523-014-0351-8DOI Listing
September 2015

Preface. Novel targets and drugs to prevent atherogenesis and its consequences.

Eur J Pharmacol 2015 Sep;763(Pt A):1-2

Department of Internal Medicine and Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.08.042DOI Listing
September 2015

High Dose Meclizine Prevents Renal Ischemia-Reperfusion Injury in Healthy Male Mice.

Authors:
Gerard A Rongen

EBioMedicine 2015 Sep 12;2(9):1012-3. Epub 2015 Sep 12.

Department of Pharmacology and Toxicology, Radboud university medical center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S23523964150015
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http://dx.doi.org/10.1016/j.ebiom.2015.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588439PMC
September 2015

Effect of metformin pretreatment on myocardial injury during coronary artery bypass surgery in patients without diabetes (MetCAB): a double-blind, randomised controlled trial.

Lancet Diabetes Endocrinol 2015 Aug 12;3(8):615-23. Epub 2015 Jul 12.

Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, Netherlands; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(15)00121-7DOI Listing
August 2015

Cardiovascular pharmacotherapy: Innovation stuck in translation.

Eur J Pharmacol 2015 Jul 24;759:200-4. Epub 2015 Mar 24.

SYstematic Review Centre for Laboratory animal Experimentation, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejphar.2015.03.035DOI Listing
July 2015

Impact of metformin on endothelial ischemia-reperfusion injury in humans in vivo: a prospective randomized open, blinded-endpoint study.

PLoS One 2014 22;9(4):e96062. Epub 2014 Apr 22.

Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands; Department of General Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096062PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996005PMC
January 2015

Shortcomings of protocols of drug trials in relation to sponsorship as identified by Research Ethics Committees: analysis of comments raised during ethical review.

BMC Med Ethics 2014 Dec 10;15:83. Epub 2014 Dec 10.

Clinical Research Centre Nijmegen, Department of Pharmacology - Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/1472-6939-15-83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269968PMC
December 2014

The cardioprotective effects of mineralocorticoid receptor antagonists.

Pharmacol Ther 2014 Apr 23;142(1):72-87. Epub 2013 Nov 23.

Department of Pharmacology and Toxicology, Radboud University Medical Centre, Nijmegen, the Netherlands; Department of General Internal Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2013.11.006DOI Listing
April 2014

It takes more than one CAMERA to study cardiovascular protection by metformin.

Lancet Diabetes Endocrinol 2014 Feb 3;2(2):105-6. Epub 2014 Feb 3.

Department of Pharmacology-Toxicology, Radboud University Medical Centre, Geert Grooteplein 10, Nijmegen, 6525GA, Netherlands.

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http://dx.doi.org/10.1016/S2213-8587(13)70207-9DOI Listing
February 2014

The effect of remote ischemic preconditioning on exercise-induced plasma troponin I appearance in healthy volunteers.

Int J Cardiol 2013 Sep 11;168(2):1612-3. Epub 2013 Feb 11.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ijcard.2013.01.029DOI Listing
September 2013

[Clopidogrel plus acetylsalicylic acid: a deadly combination].

Authors:
Gerard A Rongen

Ned Tijdschr Geneeskd 2013 ;157(25):A6221

UMC St Radboud, afd. Farmacologie-Toxicologie, Nijmegen, the Netherlands.

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September 2013

Humoral signalling compounds in remote ischaemic preconditioning of the kidney, a role for the opioid receptor.

Nephrol Dial Transplant 2013 Jul 6;28(7):1721-32. Epub 2013 Feb 6.

Department of Pharmacology and Toxicology, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfs601DOI Listing
July 2013

Aging attenuates the protective effect of ischemic preconditioning against endothelial ischemia-reperfusion injury in humans.

Am J Physiol Heart Circ Physiol 2013 Jun 19;304(12):H1727-32. Epub 2013 Apr 19.

Department of Physiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1152/ajpheart.00054.2013DOI Listing
June 2013

Metformin therapy in diabetes: the role of cardioprotection.

Curr Atheroscler Rep 2013 Apr;15(4):314

Department of Pharmacology-Toxicology 149, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s11883-013-0314-zDOI Listing
April 2013

Atorvastatin does not affect ischaemia-induced phosphatidylserine exposition in humans in-vivo.

J Atheroscler Thromb 2012 7;19(3):285-91. Epub 2011 Dec 7.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.5551/jat.10983DOI Listing
August 2012

Targeting adenosine receptors in the development of cardiovascular therapeutics.

Expert Rev Clin Pharmacol 2012 Mar;5(2):199-218

Department of Pharmacology-Toxicology 149 and Internal Medicine 463, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1586/ecp.12.8DOI Listing
March 2012

Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue.

PLoS One 2011 30;6(8):e24276. Epub 2011 Aug 30.

Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences and Nijmegen Centre for Evidence Based Practice, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024276PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168880PMC
February 2012

Short-term statin treatment does not prevent ischemia and reperfusion-induced endothelial dysfunction in humans.

J Cardiovasc Pharmacol 2012 Jan;59(1):22-8

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/FJC.0b013e318232b1a4DOI Listing
January 2012

The cardioprotective effects of metformin.

Curr Opin Lipidol 2011 Dec;22(6):445-53

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOL.0b013e32834ae1a7DOI Listing
December 2011

Remote ischaemic preconditioning by brief hind limb ischaemia protects against renal ischaemia-reperfusion injury: the role of adenosine.

Nephrol Dial Transplant 2011 Oct 21;26(10):3108-17. Epub 2011 Mar 21.

Department of Pharmacology and Toxicology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfr103DOI Listing
October 2011

Angiotensin II type 1 receptor blockade does not enhance apoptotic cell death during ischemia and reperfusion in humans in vivo.

J Cardiovasc Pharmacol 2011 Jun;57(6):702-6

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/FJC.0b013e318218ef21DOI Listing
June 2011

Reflex systemic sympatho-neural response to brachial adenosine infusion in treated heart failure.

Eur J Heart Fail 2011 May 23;13(5):475-81. Epub 2011 Feb 23.

Mount Sinai Hospital and University Health Network Division of Cardiology, Faculty of Medicine, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/eurjhf/hfr005DOI Listing
May 2011

NT5E mutations and arterial calcifications.

N Engl J Med 2011 04;364(16):1579; author reply 1579-80

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http://dx.doi.org/10.1056/NEJMc1102515DOI Listing
April 2011

The cardiovascular effects of methylxanthines.

Handb Exp Pharmacol 2011 (200):413-37

Department of Pharmacology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/978-3-642-13443-2_16DOI Listing
January 2011

Effect of different sympathetic stimuli-autonomic dysreflexia and head-up tilt-on leg vascular resistance in spinal cord injury.

Arch Phys Med Rehabil 2010 Dec;91(12):1930-5

Department of Physiology, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.1016/j.apmr.2010.09.004DOI Listing
December 2010

Upregulation of ecto-5'-nucleotidase by rosuvastatin increases the vasodilator response to ischemia.

Hypertension 2010 Oct 2;56(4):722-7. Epub 2010 Aug 2.

Departments of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.155689DOI Listing
October 2010

Rosiglitazone reduces ischaemia-reperfusion injury in patients with the metabolic syndrome.

Eur Heart J 2010 Apr 17;31(8):983. Epub 2009 Dec 17.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice and Institute for Genetic and Metabolic Disease, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehp562DOI Listing
April 2010

Sympathetic nonadrenergic transmission contributes to autonomic dysreflexia in spinal cord-injured individuals.

Hypertension 2010 Mar 25;55(3):636-43. Epub 2010 Jan 25.

Department of Physiology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.147330DOI Listing
March 2010

Endotoxin tolerance does not limit mild ischemia-reperfusion injury in humans in vivo.

Innate Immun 2009 Dec;15(6):360-7

Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/1753425909105548DOI Listing
December 2009

Rosuvastatin increases extracellular adenosine formation in humans in vivo: a new perspective on cardiovascular protection.

Arterioscler Thromb Vasc Biol 2009 Jun 9;29(6):963-8. Epub 2009 Apr 9.

Radboud University Nijmegen Medical Centre, Department of Pharmacology and Toxicology, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/ATVBAHA.108.179622DOI Listing
June 2009

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

J Cardiovasc Pharmacol 2009 May;53(5):373-8

The Hatter Cardiovascular Institute, University College London Medical School, London, United Kingdom.

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http://dx.doi.org/10.1097/FJC.0b013e31819fd4e7DOI Listing
May 2009

Acute and long-term cardiovascular effects of coffee: implications for coronary heart disease.

Pharmacol Ther 2009 Feb 11;121(2):185-91. Epub 2008 Nov 11.

Department of Pharmacology-Toxicology and Internal Medicine, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.pharmthera.2008.10.006DOI Listing
February 2009

The 22G>A polymorphism in the adenosine deaminase gene impairs catalytic function but does not affect reactive hyperaemia in humans in vivo.

Pharmacogenet Genomics 2008 Oct;18(10):843-6

Departments of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/FPC.0b013e328305e630DOI Listing
October 2008

Human in vivo research on the vascular effects of adenosine.

Eur J Pharmacol 2008 May 15;585(2-3):220-7. Epub 2008 Mar 15.

Department of Pharmacology-Toxicology and Internal Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejphar.2008.01.053DOI Listing
May 2008

Interaction study of the combined use of paroxetine and fosamprenavir-ritonavir in healthy subjects.

Antimicrob Agents Chemother 2007 Nov 10;51(11):4098-104. Epub 2007 Sep 10.

Department of Clinical Pharmacy, Radboud University Medical Centre Nijmegen, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/AAC.01243-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151442PMC
November 2007

Enhanced endothelin-1-mediated leg vascular tone in healthy older subjects.

J Appl Physiol (1985) 2007 Sep 7;103(3):852-7. Epub 2007 Jun 7.

Department of Physiology, Radboud University Nijmegen Medical Centre, Geert Grooteplein-Noord 21, 6525 EZ, Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1152/japplphysiol.00357.2007DOI Listing
September 2007

Acute elevation of plasma non-esterified fatty acids increases pulse wave velocity and induces peripheral vasodilation in humans in vivo.

Clin Sci (Lond) 2007 Jul;113(1):33-40

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1042/CS20060365DOI Listing
July 2007

The 1976C>T polymorphism in the adenosine A2A receptor gene does not affect the vasodilator response to adenosine in humans in vivo.

Pharmacogenet Genomics 2007 Jul;17(7):551-4

Department of Pharmacology, Radboud University Nijmegen Medical Center, The Netherlands.

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http://dx.doi.org/10.1097/FPC.0b013e32803fb78fDOI Listing
July 2007

Augmented hyperaemia and reduced tissue injury in response to ischaemia in subjects with the 34C > T variant of the AMPD1 gene.

Eur Heart J 2007 May 21;28(9):1085-91. Epub 2007 Mar 21.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Geert Grooteplein 21, 6525 EZ, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehm032DOI Listing
May 2007

Leg blood flow measurements using venous occlusion plethysmography during head-up tilt.

Clin Auton Res 2007 Apr 7;17(2):106-11. Epub 2007 Mar 7.

Dept of Physiology, Radboud University Nijmegen Medical Centre, Institute for Fundamental and Clinical Movement Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10286-007-0402-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914255PMC
April 2007

A causal role for endothelin-1 in the vascular adaptation to skeletal muscle deconditioning in spinal cord injury.

Arterioscler Thromb Vasc Biol 2007 Feb 22;27(2):325-31. Epub 2006 Nov 22.

Department of Physiology, Institute of Fundamental and Clinical Movement Sciences, Radboud University Nijmegen Medical Centre, Geert Grooteplein-Noord 21, 6525 EZ, Nijmegen, The Netherlands.

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https://www.ahajournals.org/doi/10.1161/01.ATV.0000253502.83
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http://dx.doi.org/10.1161/01.ATV.0000253502.83167.31DOI Listing
February 2007

Caffeine prevents protection in two human models of ischemic preconditioning.

J Am Coll Cardiol 2006 Aug 24;48(4):700-7. Epub 2006 Jul 24.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jacc.2006.04.083DOI Listing
August 2006

The effect of adenosine receptor agonists on cytokine release by human mononuclear cells depends on the specific Toll-like receptor subtype used for stimulation.

Cytokine 2006 Jul 11;35(1-2):95-9. Epub 2006 Sep 11.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.1016/j.cyto.2006.07.014DOI Listing
July 2006

Reduced adenosine receptor stimulation as a pathogenic factor in hyperhomocysteinemia.

Clin Chem Lab Med 2005 ;43(10):1001-6

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1515/CCLM.2005.175DOI Listing
December 2005

Vascular adaptation to deconditioning and the effect of an exercise countermeasure: results of the Berlin Bed Rest study.

J Appl Physiol (1985) 2005 Oct 2;99(4):1293-300. Epub 2005 Jun 2.

Department of Physiology, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.1152/japplphysiol.00118.2005DOI Listing
October 2005

In vivo evidence against a role for adenosine in the exercise pressor reflex in humans.

J Appl Physiol (1985) 2005 Aug 7;99(2):522-7. Epub 2005 Apr 7.

Dept. of Pharmacology-Toxicology 233, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1152/japplphysiol.00108.2005DOI Listing
August 2005

Oral therapy with dipyridamole limits ischemia-reperfusion injury in humans.

Clin Pharmacol Ther 2005 Jul;78(1):52-9

Department of Pharmacology-Toxicology, Radbound University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.clpt.2005.03.003DOI Listing
July 2005

Preserved contribution of nitric oxide to baseline vascular tone in deconditioned human skeletal muscle.

J Physiol 2005 Jun 31;565(Pt 2):685-94. Epub 2005 Mar 31.

Department of Pharmacology-Toxicology 233, Radboud University Nijmegen Medical Centre, Geert Grooteplein Noord 21, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1113/jphysiol.2005.085936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464521PMC
June 2005

Vascular adaptation to 4 wk of deconditioning by unilateral lower limb suspension.

Am J Physiol Heart Circ Physiol 2005 Apr 2;288(4):H1747-55. Epub 2004 Dec 2.

Dept. of Physiology 237, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1152/ajpheart.00966.2004DOI Listing
April 2005

Enhanced cellular adenosine uptake limits adenosine receptor stimulation in patients with hyperhomocysteinemia.

Arterioscler Thromb Vasc Biol 2005 Jan 11;25(1):109-14. Epub 2004 Nov 11.

Department of Pharmacology-Toxicology 233, University Medical Centre Nijmegen, Geert Grooteplein 21, 6525 EZ Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/01.ATV.0000150651.85907.69DOI Listing
January 2005

Annexin A5 scintigraphy of forearm as a novel in vivo model of skeletal muscle preconditioning in humans.

Circulation 2005 Jan 27;111(2):173-8. Epub 2004 Dec 27.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Center, Nijmegen, Geert Grooteplein 21, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/01.CIR.0000151612.02223.F2DOI Listing
January 2005

Unilateral lower limb suspension can cause deep venous thrombosis.

Am J Physiol Regul Integr Comp Physiol 2004 Jun;286(6):R1176-7

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http://dx.doi.org/10.1152/ajpregu.00718.2003DOI Listing
June 2004

Glyburide inhibits dipyridamole-induced forearm vasodilation but not adenosine-induced forearm vasodilation.

Clin Pharmacol Ther 2004 Mar;75(3):147-56

Department of Internal Medicine, University Medical Centre Nijmegen, 6500 HB Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1016/j.clpt.2003.09.016
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http://dx.doi.org/10.1016/j.clpt.2003.09.016DOI Listing
March 2004

The influence of diazepam and midazolam on adenosine-induced forearm vasodilation in humans.

J Cardiovasc Pharmacol 2004 Feb;43(2):276-80

Department of General Internal Medicine, University Medical Centre Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/00005344-200402000-00017DOI Listing
February 2004

The role of carotid chemoreceptors in the sympathetic activation by adenosine in humans.

Clin Sci (Lond) 2004 Jan;106(1):75-82

Department of General Internal Medicine, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1042/CS20030174DOI Listing
January 2004

Preserved alpha-adrenergic tone in the leg vascular bed of spinal cord-injured individuals.

Circulation 2003 Nov 13;108(19):2361-7. Epub 2003 Oct 13.

Department of Physiology, Department of Physiology, University Medical Center Nijmegen, The Netherlands .

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http://dx.doi.org/10.1161/01.CIR.0000096480.55857.3CDOI Listing
November 2003

Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia.

Cardiovasc Res 2003 Aug;59(2):271-6

Department of Pharmacology-Toxicology, University Medical Centre Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/s0008-6363(03)00462-0DOI Listing
August 2003

Caffeine and coffee tolerance.

Circulation 2003 Aug;108(6):e38-40; author reply e38-40

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August 2003

Stress susceptibility as a determinant of endothelium-dependent vascular reactivity in rat mesenteric arteries.

J Cardiovasc Pharmacol 2003 Apr;41(4):625-31

Departments of Pharmacology and Toxicology, University Medical Center Nijmegen, HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/00005344-200304000-00016DOI Listing
April 2003

Stress susceptibility as a determinant of the response to adrenergic stimuli in mesenteric resistance arteries of the rat.

J Cardiovasc Pharmacol 2002 Nov;40(5):678-83

Department of Pharmacology-Toxicology, University Medical Center Nijmegen, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/00005344-200211000-00005DOI Listing
November 2002

The role of myocardial KATP-channel blockade in the protective effects of glibenclamide against ischaemia in the rat heart.

Pharmacol Toxicol 2002 Aug;91(2):51-6

Department of Physiology, University Medical Center Nijmegen, The Netherlands.

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http://dx.doi.org/10.1034/j.1600-0773.2002.910202.xDOI Listing
August 2002

Diadenosine pentaphosphate vasodilates the forearm vascular bed: inhibition by theophylline and augmentation by dipyridamole.

Clin Pharmacol Ther 2002 Jun;71(6):448-56

Department of General Internal Medicine, University Medical Center Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1067/mcp.2002.124469
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June 2002