Geraldine Rauch

Geraldine Rauch

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Geraldine Rauch

Geraldine Rauch

Publications by authors named "Geraldine Rauch"

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Psychometric validation of the Breast Cancer Treatment Outcome Scale (BCTOS-12): a prospective cohort study.

Arch Gynecol Obstet 2019 Dec 9;300(6):1679-1686. Epub 2019 Nov 9.

Department of Gynecology and Obstetrics, University of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00404-019-05362-yDOI Listing
December 2019

Development and validation of the Heidelberg Neurological Triage System (HEINTS).

J Neurol 2019 Nov 18;266(11):2685-2698. Epub 2019 Jul 18.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00415-019-09472-0DOI Listing
November 2019

A variational approach to optimal two-stage designs.

Stat Med 2019 Sep 1;38(21):4159-4171. Epub 2019 Jul 1.

Institute of Medical Biometry and Informatics, University Medical Center Ruprecht-Karls University Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/sim.8291DOI Listing
September 2019

Refining scores based on patient reported outcomes - statistical and medical perspectives.

BMC Med Res Methodol 2019 Jul 31;19(1):167. Epub 2019 Jul 31.

Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130.3, D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12874-019-0806-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670170PMC
July 2019

[The role of biostatistics in institutional review boards].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019 Jun;62(6):751-757

Institut für medizinische Informationsverarbeitung, Biometrie und Epidemiologie, LMU München, München, Deutschland.

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http://dx.doi.org/10.1007/s00103-019-02951-9DOI Listing
June 2019

[Current challenges in the assessment of ethical proposals-aspects of digitalization and personalization in the healthcare system].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019 Jun;62(6):758-764

Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel, Paul-Ehrlich-Institut, Langen, Deutschland.

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http://dx.doi.org/10.1007/s00103-019-02955-5DOI Listing
June 2019

[Research involving human subjects-principles and challenges for the work of ethics committees].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019 06;62(6):679-681

Institut für Biometrie und Klinische Epidemiologie, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.

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http://dx.doi.org/10.1007/s00103-019-02961-7DOI Listing
June 2019

Introducing a new estimator and test for the weighted all-cause hazard ratio.

BMC Med Res Methodol 2019 06 11;19(1):118. Epub 2019 Jun 11.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Biometry and Clinical Epidemiology, Charitéplatz 1, Berlin, 10117, Germany.

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http://dx.doi.org/10.1186/s12874-019-0765-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560733PMC
June 2019

The Incidence of Acute Kidney Injury and Associated Hospital Mortality.

Dtsch Arztebl Int 2019 May;116(22):397-404

Department of Nephrology and Medical Intensive Care Medicine, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Berlin; Business Division IT, Department of Research and Teaching, Charité-Universitätsmedizin Berlin, Berlin; Institute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Berlin; Biostatistics, Clinical Research Unit, Berlin Institute of Health, Berlin; Administrative Office for Digital Transformation, Charité - -Universitätsmedizin Berlin, Berlin.

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http://dx.doi.org/10.3238/arztebl.2019.0397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676729PMC
May 2019

What makes a biostatistician?

Stat Med 2019 02 7;38(4):695-701. Epub 2018 Oct 7.

Institute of Medical Biometry and Informatics, Heidelberg University Hospital, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/sim.7998
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http://dx.doi.org/10.1002/sim.7998DOI Listing
February 2019

Hepatitis E seroprevalence in the Americas: A systematic review and meta-analysis.

Liver Int 2018 11 3;38(11):1951-1964. Epub 2018 May 3.

Department of Medicine I, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/liv.13859DOI Listing
November 2018

Cardiac Implantable Electronic Device Interrogation at Forensic Autopsy: An Underestimated Resource?

Circulation 2018 06;137(25):2730-2740

Charité-Universitaetsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology (P.L., A.S.P., M.H., P.A., L.-H.B., B.P., W.H., F.B.)

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.032367DOI Listing
June 2018

Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints.

Clin Res Cardiol 2018 May 16;107(5):437-443. Epub 2018 Feb 16.

Institute of Medical Biostatistics, Epidemiology and Informatics, University of Mainz, Mainz, Germany.

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http://dx.doi.org/10.1007/s00392-018-1205-7DOI Listing
May 2018

Development and psychometric validation of a shorter version of the Breast Cancer Treatment Outcome Scale (BCTOS-12).

Breast 2018 Apr 4;38:58-65. Epub 2018 Jan 4.

Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2017.12.002DOI Listing
April 2018

A weighted combined effect measure for the analysis of a composite time-to-first-event endpoint with components of different clinical relevance.

Stat Med 2018 02 4;37(5):749-767. Epub 2017 Dec 4.

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1002/sim.7531DOI Listing
February 2018

Blinded sample size recalculation in clinical trials with binary composite endpoints.

J Biopharm Stat 2017 13;27(4):705-715. Epub 2016 Jun 13.

a Institute of Medical Biometry and Informatics , University of Heidelberg , Heidelberg , Germany.

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http://dx.doi.org/10.1080/10543406.2016.1198371DOI Listing
January 2018

A systematic comparison of recurrent event models for application to composite endpoints.

BMC Med Res Methodol 2018 01 4;18(1). Epub 2018 Jan 4.

Institute of Medical Biometry and Informatics, Universtiy Medical Center Ruprecht-Karls Universtiy Heidelberg, Im Neuenheimer Feld 130.3, Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1186/s12874-017-0462-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755224PMC
January 2018

In obesity even young women suffer from urogynecological symptoms.

Arch Gynecol Obstet 2017 Nov 5;296(5):947-956. Epub 2017 Sep 5.

Department of Obstetrics and Gynecology, Medical School, University of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00404-017-4514-6DOI Listing
November 2017

Inter-rater reliability and double reading analysis of an automated three-dimensional breast ultrasound system: comparison of two independent examiners.

Arch Gynecol Obstet 2017 09 26;296(3):571-582. Epub 2017 Jul 26.

University Breast Unit, Department of Gynecology and Obstetrics, University of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00404-017-4473-yDOI Listing
September 2017

Functional T cells targeting tumor-associated antigens are predictive for recurrence-free survival of patients with radically operated non-small cell lung cancer.

Oncoimmunology 2017 8;6(11):e1360458. Epub 2017 Sep 8.

Regensburg Center for Interventional Immunology and Hematology Department University Clinic and University of Regensburg, Am Biopark 9, Regensburg, BY, Germany.

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http://dx.doi.org/10.1080/2162402X.2017.1360458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674973PMC
September 2017

Choice of futility boundaries for group sequential designs with two endpoints.

BMC Med Res Methodol 2017 Aug 8;17(1):119. Epub 2017 Aug 8.

Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130.3, Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1186/s12874-017-0387-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549398PMC
August 2017

Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis.

Stroke 2017 07 25;48(7):1827-1834. Epub 2017 May 25.

From the Department of Neurology, Klinikum der Universität München, Ludwig-Maximilians-University, Germany (L.K.); Department of Neurology, University of Heidelberg (L.K., C.H., P.A.R.) and Institute of Medical Biometry and Informatics (G.R.), University of Heidelberg, Germany; Department of Clinical Neuroscience, Karolinska Institute and Department of Neurology, Karolinska University Hospital, Stockholm, Sweden (N.A.); Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Germany (G.R.); Division of Applied Medicine, University of Aberdeen, Foresterhill, United Kingdom (M.J.M.); Department of Neurology, St. Bortolo Hospital, Vicenza, Italy (F.P.); and Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (K.R.L.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016876DOI Listing
July 2017

Imatinib induces sustained progression arrest in RECIST progressive desmoid tumours: Final results of a phase II study of the German Interdisciplinary Sarcoma Group (GISG).

Eur J Cancer 2017 05 8;76:60-67. Epub 2017 Mar 8.

University of Heidelberg, Mannheim University Medical Center, Interdisciplinary Tumor Center Mannheim, Sarcoma Unit, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany; University of Heidelberg, Mannheim University Medical Center, Division of Surgical Oncology, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.ejca.2017.02.001DOI Listing
May 2017

Do Contralateral Prophylactic Mastectomies Help Patients?

J Clin Oncol 2016 12 30;34(34):4191. Epub 2016 Sep 30.

Joerg Heil, University Hospital Heidelberg, Heidelberg, Germany; Ulrich Kneser, University of Heidelberg, Ludwigshafen, Germany; Andre Hennigs, Christiane Bieber, Kathrin Gschwendtner, Nicole Mueller, Geraldine Rauch, Florian Schuetz, and Christof Sohn, University Hospital Heidelberg, Heidelberg, Germany; and Thomas Kremer, University of Heidelberg, Ludwigshafen, Germany.

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http://dx.doi.org/10.1200/JCO.2016.68.2997DOI Listing
December 2016

Combined sunitinib and radiation therapy for preoperative treatment of soft tissue sarcoma: results of a phase I trial of the German interdisciplinary sarcoma group (GISG-03).

Radiat Oncol 2016 Jun 3;11:77. Epub 2016 Jun 3.

Division of Surgical, Oncology and Thoracic Surgery, Department of Surgery, University Medical Center Mannheim, University of Heidelberg, Th.-Kutzer-Ufer 1-3, Mannheim, 68137, Germany.

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http://dx.doi.org/10.1186/s13014-016-0654-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891890PMC
June 2016

Cognitive impairment is not a predictor of failure to adhere to anticoagulation of stroke patients with atrial fibrillation.

Cerebrovasc Dis 2015 7;39(5-6):325-31. Epub 2015 May 7.

Department of Neurology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000381728DOI Listing
March 2016

Sublobar Resection, Radiofrequency Ablation or Radiotherapy in Stage I Non-Small Cell Lung Cancer.

Respiration 2015 30;89(6):550-7. Epub 2015 Apr 30.

Departments of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000381555DOI Listing
March 2016

Uncoupling of PUMA Expression and Apoptosis Contributes to Functional Heterogeneity in Renal Cell Carcinoma - Prognostic and Translational Implications.

Transl Oncol 2015 Dec;8(6):480-6

Molecular Urooncology, Department of Urology, University of Heidelberg School of Medicine, Im Neuenheimer Feld 517, D-69120 Heidelberg, Germany; Center for Kidney Tumors, National Center for Tumor Diseases (NCT) and University of Heidelberg School of Medicine, Im Neuenheimer Feld 460, D-69120 Heidelberg, Germany; Department of Urology, University of Heidelberg School of Medicine, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700292PMC
December 2015

Long-term objective esthetic outcome after breast-conserving therapy.

Breast Cancer Res Treat 2015 Sep 13;153(2):345-51. Epub 2015 Aug 13.

University Breast Unit, University Hospital of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

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http://link.springer.com/content/pdf/10.1007/s10549-015-3540
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http://link.springer.com/10.1007/s10549-015-3540-y
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http://dx.doi.org/10.1007/s10549-015-3540-yDOI Listing
September 2015

Two-stage designs for cross-over bioequivalence trials.

Stat Med 2015 Jul 24;34(16):2403-16. Epub 2015 Mar 24.

Institute of Medical Biometry and Informatics, University of Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1002/sim.6487DOI Listing
July 2015

Psychosocial and physical outcome following kidney donation-a retrospective analysis.

Transpl Int 2015 Apr 26;28(4):416-28. Epub 2015 Jan 26.

Department of Nephrology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/tri.12509DOI Listing
April 2015

Combination of trabectedin and gemcitabine for advanced soft tissue sarcomas: results of a phase I dose escalating trial of the German Interdisciplinary Sarcoma Group (GISG).

Mar Drugs 2015 Jan 13;13(1):379-88. Epub 2015 Jan 13.

University of Heidelberg, Mannheim University Medical Center, Interdisciplinary Tumor Center Mannheim, Sarcoma Unit, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

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http://dx.doi.org/10.3390/md13010379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306943PMC
January 2015

Opportunities and challenges of clinical trials in cardiology using composite primary endpoints.

World J Cardiol 2015 Jan;7(1):1-5

Geraldine Rauch, Svenja Schüler, Meinhard Kieser, Institute of Medical Biometry and Informatics, University of Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.4330/wjc.v7.i1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306200PMC
January 2015

Easily applicable multiple testing procedures to improve the interpretation of clinical trials with composite endpoints.

Int J Cardiol 2014 Jul 9;175(1):126-32. Epub 2014 May 9.

Institute of Medical Biometry and Informatics, University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2014.04.267DOI Listing
July 2014

Opportunities and challenges of combined effect measures based on prioritized outcomes.

Stat Med 2014 Mar 13;33(7):1104-20. Epub 2013 Oct 13.

Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 305, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/sim.6010DOI Listing
March 2014

Atrial fibrillation and prestroke cognitive impairment in stroke.

J Neurol 2014 Mar 12;261(3):546-53. Epub 2014 Jan 12.

Department of Neurology, University of Heidelberg, INF 400, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00415-013-7233-3DOI Listing
March 2014

Left atrial appendage occlusion in atrial fibrillation after intracranial hemorrhage.

Neurology 2014 Jan 6;82(2):135-8. Epub 2013 Dec 6.

From the Department of Neurology (S.H., T.R., R.V.), Department of Cardiology (C.Z., U.K., N.G., S.H.), and Institute of Medical Biometry and Informatics (G.R.), University of Heidelberg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000000022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897438PMC
January 2014

Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters.

Br J Clin Pharmacol 2013 Nov;76(5):787-96

Department of Clinical Pharmacology and Pharmacoepidemiology, University Hospital Heidelberg, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1111/bcp.12079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853537PMC
November 2013

Normal breast tissue stiffness measured by a new ultrasound technique: virtual touch tissue imaging quantification (VTIQ).

Eur J Radiol 2013 Nov 8;82(11):e676-9. Epub 2013 Aug 8.

Breast Unit, University of Heidelberg, Im Neuenheimer Feld 440, D-69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2013.06.029DOI Listing
November 2013

Phase I trial of concurrent sunitinib and radiation therapy as preoperative treatment for soft tissue sarcoma.

BMJ Open 2013 Sep 18;3(9):e003626. Epub 2013 Sep 18.

Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1136/bmjopen-2013-003626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780318PMC
September 2013

Cardiac rehabilitation mortality trends: how far from a true picture are we?

Heart 2013 May 19;99(9):593-5. Epub 2013 Feb 19.

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http://dx.doi.org/10.1136/heartjnl-2012-303365DOI Listing
May 2013

Multiplicity adjustment for composite binary endpoints.

Methods Inf Med 2012 24;51(4):309-17. Epub 2012 Apr 24.

Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.3414/ME11-01-0044DOI Listing
January 2013

Aesthetics in breast conserving therapy: do objectively measured results match patients' evaluations?

Ann Surg Oncol 2011 Jan 10;18(1):134-8. Epub 2010 Aug 10.

University Breast Center Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1245/s10434-010-1252-4DOI Listing
January 2011

A new outlier identification test for method comparison studies based on robust regression.

J Biopharm Stat 2011 Jan;21(1):151-69

Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1080/10543401003650275DOI Listing
January 2011

Effect of early short-term cardiac rehabilitation after acute ST-elevation and non-ST-elevation myocardial infarction on 1-year mortality.

Curr Med Res Opin 2010 Apr;26(4):803-11

Institut für Herzinfarktforschung Ludwigshafen an der Universität Heidelberg, Ludwigshafen, Germany.

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http://dx.doi.org/10.1185/03007991003604216DOI Listing
April 2010