Publications by authors named "Gerald W Prager"

54Publications

Outcome of Targeted Therapy Recommendations for Metastatic and Recurrent Head and Neck Cancers.

Cancers (Basel) 2020 Nov 15;12(11). Epub 2020 Nov 15.

Department of Medicine I, Clinical Division of Oncology, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers12113381DOI Listing
November 2020

Personalized Adjuvant Treatment of Colon Cancer.

Visc Med 2020 Oct 29;36(5):397-406. Epub 2020 Jun 29.

Department of Medicine I, Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000508175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590780PMC
October 2020

Applied precision medicine in metastatic pancreatic ductal adenocarcinoma.

Ther Adv Med Oncol 2020 10;12:1758835920938611. Epub 2020 Jul 10.

Department of Medicine I, Clinical Division of Oncology, Comprehensive Cancer Center Vienna, Precision Cancer Medicine Unit, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1177/1758835920938611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357054PMC
July 2020

First evidence for the antitumor activity of nanoliposomal irinotecan with 5-fluorouracil and folinic acid in metastatic biliary tract cancer.

Cancer Chemother Pharmacol 2020 Jul 18;86(1):109-115. Epub 2020 Jun 18.

Clinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00280-020-04094-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338813PMC
July 2020

Gender differences in molecular-guided therapy recommendations for metastatic malignant mesothelioma.

Thorac Cancer 2020 07 21;11(7):1979-1988. Epub 2020 May 21.

Division of Clinical Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/1759-7714.13491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327667PMC
July 2020

Impact of New Chemotherapy Regimens on the Treatment Landscape and Survival of Locally Advanced and Metastatic Pancreatic Cancer Patients.

J Clin Med 2020 Feb 28;9(3). Epub 2020 Feb 28.

Department of Medicine I, Division of Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/jcm9030648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141274PMC
February 2020

Treatment Algorithm for Patients With Gastric Adenocarcinoma: An Austrian Consensus on Systemic Therapy.

Anticancer Res 2019 Sep;39(9):4589-4596

Third Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectious Diseases and Rheumatology, Oncology Centre, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.21873/anticanres.13638DOI Listing
September 2019

A real-world analysis of second-line treatment options in pancreatic cancer: liposomal-irinotecan plus 5-fluorouracil and folinic acid.

Ther Adv Med Oncol 2019 17;11:1758835919853196. Epub 2019 Jul 17.

Department of Medicine I, Division of Oncology, Comprehensive Cancer Center, Medical University Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1177/1758835919853196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640066PMC
July 2019

Third- or Later-line Therapy for Metastatic Colorectal Cancer: Reviewing Best Practice.

Clin Colorectal Cancer 2019 03 16;18(1):e117-e129. Epub 2018 Nov 16.

Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2018.11.002DOI Listing
March 2019

Plasma levels of interleukin-33 and soluble suppression of tumorigenicity 2 in patients with advanced pancreatic ductal adenocarcinoma undergoing systemic chemotherapy.

Med Oncol 2018 Nov 13;36(1). Epub 2018 Nov 13.

Division of Oncology, Department of Medicine I, Comprehensive Cancer Center, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://link.springer.com/10.1007/s12032-018-1223-3
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http://dx.doi.org/10.1007/s12032-018-1223-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244890PMC
November 2018

SERPINB7 Expression Predicts Poor Pancreatic Cancer Survival Upon Gemcitabine Treatment.

Transl Oncol 2019 Jan 20;12(1):15-23. Epub 2018 Sep 20.

Department of Internal Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2018.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149193PMC
January 2019

Optimizing Treatment Sequence for Late-line Metastatic Colorectal Cancer Patients Using Trifluridine/Tipiracil and Regorafenib.

Clin Colorectal Cancer 2018 12 8;17(4):274-279. Epub 2018 Jun 8.

Clinical Division of Oncology, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2018.05.012DOI Listing
December 2018

Analysis of 10 Adrenocortical Carcinoma Patients in the Cohort of the Precision Medicine Platform MONDTI.

Oncology 2018 14;94(5):306-310. Epub 2018 Feb 14.

Division of Oncology, Department of Medicine I, Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000486678DOI Listing
May 2018

Cross-over comparison and new chemotherapy regimens in metastatic pancreatic cancer.

Memo 2017 7;10(3):136-140. Epub 2017 Sep 7.

Department of Medicine I, Division of Oncology, Comprehensive Cancer Center, Medical University Vienna - General Hospital, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s12254-017-0352-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605578PMC
September 2017

Integrins in the Spotlight of Cancer.

Int J Mol Sci 2016 Dec 6;17(12). Epub 2016 Dec 6.

Department of Internal Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.3390/ijms17122037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187837PMC
December 2016

Decreased platelet reactivity in patients with cancer is associated with high risk of venous thromboembolism and poor prognosis.

Thromb Haemost 2017 01 20;117(1):90-98. Epub 2016 Oct 20.

Cihan Ay, MD, Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria, Tel.: +43 1 40400 44100, Fax: +43 1 40400 40300, E-mail:

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http://dx.doi.org/10.1160/TH16-02-0123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522348PMC
January 2017

Sustained Response to Vemurafenib in a BRAF-Mutated Anaplastic Thyroid Carcinoma Patient.

Thyroid 2016 10 27;26(10):1515-1516. Epub 2016 Sep 27.

1 Department of Medicine I, Comprehensive Cancer Center Vienna; Medical University of Vienna , Vienna, Austria .

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http://dx.doi.org/10.1089/thy.2015.0575DOI Listing
October 2016

Integrin beta-3 genetic variants and risk of venous thromboembolism in colorectal cancer patients.

Thromb Res 2015 Nov 28;136(5):865-9. Epub 2015 Aug 28.

Department of Internal Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496222PMC
November 2015

In vivo Tube Assay: An Optimised Protocol of the Directed in vivo Angiogenesis Assay by Implementing Immunohistochemistry.

J Vasc Res 2015 31;52(2):116-26. Epub 2015 Jul 31.

Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000434751DOI Listing
December 2015

Effects of cilengitide in osteoclast maturation and behavior.

Exp Cell Res 2015 Sep 21;337(1):68-75. Epub 2015 Jul 21.

Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2015.07.018DOI Listing
September 2015

Baseline carcinoembryonic antigen (CEA) serum levels predict bevacizumab-based treatment response in metastatic colorectal cancer.

Cancer Sci 2014 Aug 31;105(8):996-1001. Epub 2014 Jul 31.

Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1111/cas.12451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317865PMC
August 2014

CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior.

Mol Cancer 2013 Dec 21;12:169. Epub 2013 Dec 21.

Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1186/1476-4598-12-169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879186PMC
December 2013

Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis.

Cancer Res 2013 Nov 11;73(22):6584-96. Epub 2013 Oct 11.

Authors' Affiliations: Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center; Institute of Clinical Pathology; Department of Vascular Biology and Thrombosis Research, Centre for Bio-Molecular Medicine and Pharmacology, Medical University of Vienna, Vienna, Austria; and Tumor Immunology Laboratory, LIFE-Center, Klinikum Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0123DOI Listing
November 2013

The urokinase receptor (CD87) represents a central mediator of growth factor-induced endothelial cell migration.

Thromb Haemost 2012 Aug 10;108(2):357-66. Epub 2012 Jul 10.

Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center Vienna, Medical University Vienna, Austria.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH11-12-0868
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http://dx.doi.org/10.1160/TH11-12-0868DOI Listing
August 2012

Angiogenesis in cancer: Anti-VEGF escape mechanisms.

Transl Lung Cancer Res 2012 Mar;1(1):14-25

Medical University of Vienna, Comprehensive Cancer Center Vienna, Department of Medicine I, Austria.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2011.11.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367591PMC
March 2012

Density enhanced phosphatase-1 down-regulates urokinase receptor surface expression in confluent endothelial cells.

Blood 2011 Apr 8;117(15):4154-61. Epub 2011 Feb 8.

Department of Vascular Biology and Thrombosis Research, Center for Biomolecular Medicine and Pharmacology, Medical University Vienna, Vienna, Austria.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-09-30
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http://dx.doi.org/10.1182/blood-2010-09-307694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087537PMC
April 2011

Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein.

Blood 2009 Feb 23;113(6):1383-90. Epub 2008 Oct 23.

Department of Vascular Biology and Thrombosis Research, Centre for Bio-Molecular Medicine and Pharmacology, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2008-06-164210DOI Listing
February 2009

CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling.

J Biol Chem 2007 Aug 27;282(33):24477-84. Epub 2007 Jun 27.

Department of Medicine, University of California San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1074/jbc.M702877200DOI Listing
August 2007

uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view.

Thromb Haemost 2007 Mar;97(3):336-42

Department of Vascular Biology and Thrombosis Research, Center for Biomolecular Medicine and Pharmacology, Medical University of Vienna, Vienna, Austria.

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March 2007

Genetic determinants: is there an "atherosclerosis gene"?

Acta Med Austriaca 2004 Feb;31(1):1-7

Department of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria.

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February 2004

Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells.

Blood 2004 Feb 2;103(3):955-62. Epub 2003 Oct 2.

Department of Vascular Biology and Thrombosis Research, Schwarzspanierstrasse 17, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2003-07-2214DOI Listing
February 2004

Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients.

Arterioscler Thromb Vasc Biol 2003 Mar 30;23(3):397-403. Epub 2003 Jan 30.

Clinic of Internal Medicine II, Department of Angiology, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1161/01.ATV.0000059384.34874.F0DOI Listing
March 2003

Plasminogen activator inhibitor 1: physiological and pathophysiological roles.

News Physiol Sci 2002 Apr;17:56-61

Department of Vascular Biology and Thrombosis Research, University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1152/nips.01369.2001DOI Listing
April 2002