Gerald Quon

Gerald Quon

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Gerald Quon

Gerald Quon

Publications by authors named "Gerald Quon"

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Correction to: scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data.

Genome Biol 2019 11 21;20(1):247. Epub 2019 Nov 21.

Graduate Group in Biostatistics, University of California, Davis, Davis, CA, USA.

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http://dx.doi.org/10.1186/s13059-019-1822-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868864PMC
November 2019

scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data.

Genome Biol 2019 09 9;20(1):193. Epub 2019 Sep 9.

Graduate Group in Biostatistics, University of California, Davis, Davis, CA, USA.

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http://dx.doi.org/10.1186/s13059-019-1806-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734238PMC
September 2019

scAlign: a tool for alignment, integration, and rare cell identification from scRNA-seq data.

Genome Biol 2019 08 14;20(1):166. Epub 2019 Aug 14.

Graduate Group in Computer Science, University of California, Davis, Davis, CA, USA.

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http://dx.doi.org/10.1186/s13059-019-1766-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693154PMC
August 2019

A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing.

Anal Chem 2018 12 13;90(23):13969-13977. Epub 2018 Nov 13.

Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering and Department of Electrical and Computer Engineering , University of California , Davis , California 95616 , United States.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b03456
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http://dx.doi.org/10.1021/acs.analchem.8b03456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467812PMC
December 2018

Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases.

Nat Methods 2016 Apr 7;13(4):366-70. Epub 2016 Mar 7.

Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nmeth.3799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967716PMC
April 2016

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.

N Engl J Med 2015 Sep 19;373(10):895-907. Epub 2015 Aug 19.

From Beth Israel Deaconess Medical Center and Hebrew SeniorLife, Gerontology Division, Harvard Medical School, Boston (M.C., Y.-H.H.); Massachusetts Institute of Technology (MIT) Computer Science and Artificial Intelligence Laboratory (M.C., G.Q., W.M., N.A.A., M.K.), and Broad Institute of MIT and Harvard, Cambridge (M.C., G.Q., W.M., M.K.); Clinical Cooperation Group "Nutrigenomics and Type 2 Diabetes," Helmholtz Center Munich (M.C., H.H.), and Else Kröner-Fresenius Center for Nutritional Medicine, Klinikum rechts der Isar, ZIEL-Institute for Food and Health, Technische Universität München (M.C., V.G., I.S.S., H.H.), Munich, Germany; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, and Hormone Laboratory, Haukeland University Hospital, Bergen, Norway (S.N.D., C.H., G.M.); Program in Developmental and Stem Cell Biology, Hospital for Sick Children, and Department of Molecular Genetics, University of Toronto (K.-H.K., V.P., J.L., C.-C.H.), and Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital (J.L.B., D.J.D.), Toronto; and the Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden (P.-A.S.).

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http://dx.doi.org/10.1056/NEJMoa1502214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959911PMC
September 2015

ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles.

BMC Bioinformatics 2015 May 14;16:156. Epub 2015 May 14.

Informatics and Biocomputing Program, Ontario Institute for Cancer Research, 661 University Avenue, Toronto, Suite 510, M5G 0A3, ON, Canada.

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http://dx.doi.org/10.1186/s12859-015-0597-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429941PMC
May 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530010PMC
February 2015

Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease.

Nature 2015 Feb;518(7539):365-9

1] Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA [2] Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/nature14252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530583PMC
February 2015

PERT: a method for expression deconvolution of human blood samples from varied microenvironmental and developmental conditions.

PLoS Comput Biol 2012 20;8(12):e1002838. Epub 2012 Dec 20.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pcbi.1002838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527275PMC
May 2013

Patterns of methylation heritability in a genome-wide analysis of four brain regions.

Nucleic Acids Res 2013 Feb 8;41(4):2095-104. Epub 2013 Jan 8.

eScience Group, Microsoft Research, 1100 Glendon Avenue, Suite PH1, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1093/nar/gks1449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575819PMC
February 2013

Unsupervised detection of genes of influence in lung cancer using biological networks.

Bioinformatics 2011 Nov 28;27(22):3166-72. Epub 2011 Sep 28.

Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada.

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http://bioinformatics.oxfordjournals.org/content/early/2011/
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http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/btr533DOI Listing
November 2011

Predicting in vivo binding sites of RNA-binding proteins using mRNA secondary structure.

RNA 2010 Jun 23;16(6):1096-107. Epub 2010 Apr 23.

Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1E3, Canada.

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http://dx.doi.org/10.1261/rna.2017210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874161PMC
June 2010

ISOLATE: a computational strategy for identifying the primary origin of cancers using high-throughput sequencing.

Bioinformatics 2009 Nov 19;25(21):2882-9. Epub 2009 Jun 19.

Department of Computer Science, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btp378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781747PMC
November 2009

Conservation of core gene expression in vertebrate tissues.

J Biol 2009 16;8(3):33. Epub 2009 Apr 16.

Department of Molecular Genetics, University of Toronto, 160 College Street, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1186/jbiol130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689434PMC
October 2009

Jabiru: harnessing Java 3D behaviors for device and display portability.

IEEE Comput Graph Appl 2005 Mar-Apr;25(2):70-80

University of Calgary.

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http://dx.doi.org/10.1109/mcg.2005.42DOI Listing
April 2005

4D bioinformatics: a new look at the ribosome as an example.

IUBMB Life 2003 Apr-May;55(4-5):279-83

University of Calgary, Faculty o Medicine, Sun Center of Excellence for Visual Genomics, 3330 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.

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http://dx.doi.org/10.1080/1521654031000136255DOI Listing
March 2004