Gerald P Linette

Gerald P Linette

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Gerald P Linette

Gerald P Linette

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Primary Bone Tumors: Challenges and Opportunities for CAR-T Therapies.

J Bone Miner Res 2019 Oct;34(10):1780-1788

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/jbmr.3852DOI Listing
October 2019

Tumor-Infiltrating Lymphocytes in the Checkpoint Inhibitor Era.

Curr Hematol Malig Rep 2019 08;14(4):286-291

Center for Cellular Immunotherapies and the Parker Institute for Cancer Immunotherapy, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s11899-019-00523-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642683PMC
August 2019

RNA-seq for identification of therapeutically targetable determinants of immune activation in human glioblastoma.

J Neurooncol 2019 Jan 23;141(1):95-102. Epub 2018 Oct 23.

Division of Hematology/Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11060-018-03010-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342649PMC
January 2019

CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges.

Neuro Oncol 2018 10;20(11):1429-1438

Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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https://academic.oup.com/neuro-oncology/article/20/11/1429/4
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http://dx.doi.org/10.1093/neuonc/noy032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176794PMC
October 2018

Health-related quality of life in patients with malignant melanoma by stage and treatment status.

J Am Acad Dermatol 2018 Jun 12. Epub 2018 Jun 12.

Washington University School of Medicine in St. Louis, Division of Dermatology. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2018.06.007DOI Listing
June 2018

CAR T-Cell Therapies in Glioblastoma: A First Look.

Clin Cancer Res 2018 02 20;24(3):535-540. Epub 2017 Nov 20.

Center for Cellular Immunotherapies and Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-2871DOI Listing
February 2018

Metastatic melanoma after solid organ transplantation: An interdisciplinary, institution-based review of management with systemic and targeted therapies.

J Am Acad Dermatol 2018 01;78(1):184-185

Division of Dermatology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622173193
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http://dx.doi.org/10.1016/j.jaad.2017.06.031DOI Listing
January 2018

Vemurafenib treatment for patients with locally advanced, unresectable stage IIIC or metastatic melanoma and activating exon 15 BRAF mutations other than V600E.

Melanoma Res 2017 12;27(6):585-590

aDepartment of Internal Medicine, Advocate Medical Group - Oncology North, Park Ridge, Illinois bMelanoma Research Clinic, University of Colorado Cancer Center, Aurora, Colorado cDepartment of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia dDepartment of Hematology and Oncology, The University of Arizona Cancer Center, Tucson, Arizona eDepartment of Medicine, Washington University School of Medicine, St Louis, Missouri fDepartment of Hematology-Oncology, Vanderbilt University Medical Center, Nashville, Tennessee gDepartment of Surgery, Columbia University Medical Center, New York, New York hDepartment of Medical Oncology, Texas Oncology, Dallas, Texas iDepartment of Medicine, Jonsson Comprehensive Cancer Center at University of California jDepartment of Immuno-Oncology, The Angeles Clinic and Research Institute, Los Angeles kDepartment of Oncology, Moores Cancer Center, University of California, San Diego, La Jolla lGenentech Inc., South San Francisco, California mMid Ohio Oncology and Hematology Inc., Columbus, Ohio nDepartment of Melanoma, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC oDepartment of Pathology, University of Pittsburgh Cancer Institute and University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania pDepartment of Melanoma, Carol G. Simon Cancer Center, Atlantic Health System, Morristown, New Jersey, USA.

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http://Insights.ovid.com/crossref?an=00008390-201712000-0000
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http://dx.doi.org/10.1097/CMR.0000000000000398DOI Listing
December 2017

Neoantigen Vaccines Pass the Immunogenicity Test.

Trends Mol Med 2017 10 31;23(10):869-871. Epub 2017 Aug 31.

Department of Pathology and Laboratory Medicine, Parker Institute for Cancer Immunotherapy and Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5157, USA.

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http://dx.doi.org/10.1016/j.molmed.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624828PMC
October 2017

Noninvasive Determination of Melanoma Depth using a Handheld Photoacoustic Probe.

J Invest Dermatol 2017 06 3;137(6):1370-1372. Epub 2017 Feb 3.

Washington University School of Medicine, Division of Dermatology, St. Louis, Missouri, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963508PMC
June 2017

Management Controversies in Head and Neck Melanoma: A Systematic Review.

JAMA Facial Plast Surg 2017 Jan;19(1):53-62

Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head & Neck Surgery, Johns Hopkins University School of Medicine, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamafacial.2016.1038DOI Listing
January 2017

A case of recurrent bilateral uveitis independently associated with dabrafenib and pembrolizumab therapy.

Am J Ophthalmol Case Rep 2016 Jul 13;2:23-25. Epub 2016 Apr 13.

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.ajoc.2016.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757367PMC
July 2016

pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens.

Genome Med 2016 Jan 29;8(1):11. Epub 2016 Jan 29.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1186/s13073-016-0264-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733280PMC
January 2016

Phase 2 study of sunitinib in patients with metastatic mucosal or acral melanoma.

Cancer 2015 Nov 11;121(22):4007-15. Epub 2015 Aug 11.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.29622DOI Listing
November 2015

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma.

J Clin Oncol 2015 Sep 26;33(25):2780-8. Epub 2015 May 26.

Robert H.I. Andtbacka, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT; Howard L. Kaufman, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Frances Collichio, University of North Carolina Medical Center, Chapel Hill, NC; Thomas Amatruda, Minnesota Oncology, Fridley, MN; Neil Senzer, Mary Crowley Cancer Research Center, Dallas; Merrick Ross, University of Texas MD Anderson Cancer Center, Houston, TX; Jason Chesney, University of Louisville, Louisville, KY; Keith A. Delman, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA; Lynn E. Spitler, Northern California Melanoma Center, San Francisco; Gregory A. Daniels, University of California San Diego Medical Center, Moores Cancer Center, La Jolla; Yining Ye, Bin Yao, Ai Li, Ari Vander Walde, and Jennifer Gansert, Amgen, Thousand Oaks, CA; Igor Puzanov, Vanderbilt University, Nashville, TN; Sanjiv S. Agarwala, St Luke's University Hospital and Health Network, Bethlehem, and Temple University School of Medicine, Philadelphia, PA; Mohammed Milhem, University of Iowa Hospitals and Clinics, Iowa City, IA; Lee Cranmer, University of Arizona, Tucson, AZ; Brendan Curti, Earle A. Chiles Research Institute, Portland, OR; Karl Lewis, University of Colorado Cancer Center, Aurora, CO; Troy Guthrie, Baptist Cancer Institute, Jacksonville; Jonathan S. Zager, Moffitt Cancer Center, Tampa, FL; Gerald P. Linette, Washington University School of Medicine, St Louis, MO; Kevin Harrington, Institute of Cancer Research, Royal Marsden Hospital, London; Mark R. Middleton, National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom; Wilson H. Miller Jr, McGill University, Montreal, Quebec, Canada; and Susan Doleman and Robert S. Coffin, Amgen, Woburn, MA.

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http://www.surgonc.org/docs/default-source/fellows-articles-
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http://jco.ascopubs.org/content/early/2015/06/16/JCO.2014.58
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http://jco.ascopubs.org/content/suppl/2015/05/26/JCO.2014.58
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http://dx.doi.org/10.1200/JCO.2014.58.3377DOI Listing
September 2015

Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.

N Engl J Med 2015 May 20;372(21):2006-17. Epub 2015 Apr 20.

From Memorial Sloan Kettering Cancer Center (M.A.P., J.D.W.), Weill Cornell Medical College (M.A.P., J.D.W.), and New York University, Perlmutter Cancer Center (A.C.P.) - all in New York; J. Graham Brown Cancer Center, University of Louisville, Louisville, KY (J.C.); Institute Gustave Roussy, Villejuif (C.R.), Paris-Sud University, Orsay (C.R.), and Institut Universitaire du Cancer, Toulouse (N.M.) - all in France; Huntsman Cancer Institute, Salt Lake City (K.G.); Beth Israel Deaconess Medical Center (D. McDermott) and Dana-Farber Cancer Institute (P.A.O., F.S.H.) - both in Boston; Washington University in St. Louis, St. Louis (G.P.L.); Greenville Health System, Greenville, SC (J.K.G.); St. Luke's Cancer Center, Bethlehem, PA (S.S.A.); University of New Mexico, Albuquerque (M.S.); Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland (M.S.E.); California Pacific Center for Melanoma Research, San Francisco (D. Minor); Duke University, Durham, NC (A.K.S.); Oregon Health and Science University, Portland (M.T.); Bristol-Myers Squibb, Lawrenceville, NJ (C.H.); and Bristol-Myers Squibb, Wallingford, CT (L.M.R., P.G.).

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http://dx.doi.org/10.1056/NEJMoa1414428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744258PMC
May 2015

Histopathologic characteristics of therapy-associated cutaneous neoplasms with vemurafenib, a selective BRAF kinase inhibitor, used in the treatment of melanoma.

J Cutan Pathol 2014 Jul 29;41(7):568-75. Epub 2014 Apr 29.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.

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http://doi.wiley.com/10.1111/cup.12346
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http://dx.doi.org/10.1111/cup.12346DOI Listing
July 2014

Codeletions at 1p and 19q predict a lower risk of pseudoprogression in oligodendrogliomas and mixed oligoastrocytomas.

Neuro Oncol 2014 Jan 26;16(1):123-30. Epub 2013 Nov 26.

Corresponding author: David D. Tran, MD, PhD, Department of Medicine, Division of Medical Oncology, Neuro-Oncology Program, Washington University School of Medicine, Campus Box 8069, 660 South Euclid Avenue, Saint Louis, MO 63110.

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/not142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870829PMC
January 2014

Dendritic cell-based vaccines: Shining the spotlight on signal 3.

Oncoimmunology 2013 Nov 10;2(11):e26512. Epub 2013 Oct 10.

Department of Medicine; Division of Oncology; Washington University School of Medicine; St. Louis, MO USA.

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http://dx.doi.org/10.4161/onci.26512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881596PMC
November 2013

IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity.

J Clin Invest 2013 Aug 11;123(8):3383-94. Epub 2013 Jul 11.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1172/JCI68395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726168PMC
August 2013

Neoadjuvant treatment of a solitary melanoma brain metastasis with vemurafenib.

J Clin Oncol 2013 Jan 10;31(3):e40-3. Epub 2012 Dec 10.

Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1200/JCO.2012.43.7061DOI Listing
January 2013

Amino-terminal extended peptide single-chain trimers are potent synthetic agonists for memory human CD8+ T cells.

J Immunol 2012 Jun 9;188(12):5839-49. Epub 2012 May 9.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.1103647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370155PMC
June 2012

Oligodendrogliomas in children.

J Neurooncol 2012 Jan 13;106(2):377-82. Epub 2011 Aug 13.

Department of Radiation Oncology and Mallinckrodt Institute of Radiology, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s11060-011-0674-6DOI Listing
January 2012

Hepatic metastasis from uveal melanoma: angiographic pattern predictive of survival after hepatic arterial chemoembolization.

Arch Ophthalmol 2009 May;127(5):628-32

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1001/archophthalmol.2009.45DOI Listing
May 2009

CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion.

Immunol Cell Biol 2009 Feb 11;87(2):167-77. Epub 2008 Nov 11.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://doi.wiley.com/10.1038/icb.2008.80
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http://dx.doi.org/10.1038/icb.2008.80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717334PMC
February 2009

Hepatic arterial chemoembolization for management of metastatic melanoma.

AJR Am J Roentgenol 2008 Jan;190(1):99-104

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.2214/AJR.07.2675DOI Listing
January 2008

Melanocyte receptors: clinical implications and therapeutic relevance.

Dermatol Clin 2007 Oct;25(4):541-57, viii-ix

Division of Dermatopathology and Dermatology, Department of Pathology and Laboratory Medicine, Albany Medical College MC-81, 47 New Scotland Avenue, Albany, NY 12208, USA.

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http://dx.doi.org/10.1016/j.det.2007.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732336PMC
October 2007

Biomarkers in melanoma: stage III and IV disease.

Expert Rev Mol Diagn 2005 Jan;5(1):65-74

Washington University School of Medicine, Division of Oncology, Campus Box 8056, St. Louis, MO 63110, USA.

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http://www.tandfonline.com/doi/full/10.1586/14737159.5.1.65
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http://dx.doi.org/10.1586/14737159.5.1.65DOI Listing
January 2005

Targeted therapies for cancer 2004.

Am J Clin Pathol 2004 Oct;122(4):598-609

Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208, USA.

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http://dx.doi.org/10.1309/5CWP-U41A-FR1V-YM3FDOI Listing
October 2004

Pharmacogenomics.

Adv Anat Pathol 2004 Jul;11(4):211-20

Division of Molecular Medicine, Millennium Pharmaceuticals, Inc, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1097/01.pap.0000131825.77317.eeDOI Listing
July 2004

Targeted therapy in breast cancer: the HER-2/neu gene and protein.

Mol Cell Proteomics 2004 Apr 3;3(4):379-98. Epub 2004 Feb 3.

Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, NY 12208, USA.

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http://dx.doi.org/10.1074/mcp.R400001-MCP200DOI Listing
April 2004

Breast cancer biomarkers and molecular medicine: part II.

Expert Rev Mol Diagn 2004 Mar;4(2):169-88

Department of Pathology and Laboratory Medicine, MC 80 Albany Medical College, 47 New Scotland Avenue, Albany, NY 12208, USA.

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http://dx.doi.org/10.1586/14737159.4.2.169DOI Listing
March 2004

The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy.

Oncologist 2003 ;8(4):307-25

Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, New York 12208, USA.

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http://dx.doi.org/10.1634/theoncologist.8-4-307DOI Listing
December 2003

HER-2/neu testing in breast cancer.

Am J Clin Pathol 2003 Dec;120 Suppl:S53-71

Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208, USA.

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http://dx.doi.org/10.1309/949FPQ1AQ3P0RLC0DOI Listing
December 2003

DNA ploidy and cell cycle analysis in breast cancer.

Am J Clin Pathol 2003 Dec;120 Suppl:S72-84

Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208, USA.

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https://academic.oup.com/ppr/article/2291991/DNA
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http://dx.doi.org/10.1309/QD096UGF70T5H46GDOI Listing
December 2003

Malignant melanoma 2003: predisposition, diagnosis, prognosis, and staging.

Am J Clin Pathol 2003 Dec;120 Suppl:S101-27

Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208, USA.

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https://academic.oup.com/ppr/article-lookup/doi/10.1309/J9M2
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http://dx.doi.org/10.1309/J9M2NUM9MHYLN3DQDOI Listing
December 2003

Breast cancer biomarkers and molecular medicine.

Expert Rev Mol Diagn 2003 Sep;3(5):573-85

Department of Pathology and Laboratory Medicine, MC 80 Albany Medical College, 47 New Scotland Avenue, Albany, NY 12208, USA.

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http://dx.doi.org/10.1586/14737159.3.5.573DOI Listing
September 2003

Biomarkers in melanoma: staging, prognosis and detection of early metastases.

Expert Rev Mol Diagn 2003 May;3(3):303-30

Division of Dermatopathology, Albany Medical College MC-81, Albany, NY 12208, USA.

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http://dx.doi.org/10.1586/14737159.3.3.303DOI Listing
May 2003

Biomarkers in melanoma: predisposition, screening and diagnosis.

Expert Rev Mol Diagn 2003 Mar;3(2):163-84

Division of DermatoPathology, Albany Medical College, NY 12208, USA.

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http://www.tandfonline.com/doi/full/10.1586/14737159.3.2.163
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http://dx.doi.org/10.1586/14737159.3.2.163DOI Listing
March 2003

Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity.

J Immunol 2002 Jul;169(1):531-9

Division of Hematology-Oncology, Massachusetts General Hospital, and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.

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http://www.jimmunol.org/content/169/1/531.full.pdf
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http://dx.doi.org/10.4049/jimmunol.169.1.531DOI Listing
July 2002

Hypopigmentation associated with an adenovirus-mediated gp100/MART-1-transduced dendritic cell vaccine for metastatic melanoma.

Arch Dermatol 2002 Jun;138(6):799-802

Department of Dermatology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1001/archderm.138.6.799DOI Listing
June 2002