Gerald Hoefler

Gerald Hoefler

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Gerald Hoefler

Gerald Hoefler

Publications by authors named "Gerald Hoefler"

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Tumor Macroenvironment: An Update.

Pathobiology 2019 Sep 4:1-3. Epub 2019 Sep 4.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria,

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http://dx.doi.org/10.1159/000502097DOI Listing
September 2019

Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function.

Free Radic Biol Med 2019 May 5;136:118-134. Epub 2019 Apr 5.

The Heart Research Institute, Newtown, NSW, Australia; Faculty of Medicine, The University of Sydney, NSW, Australia; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.04.003DOI Listing
May 2019

Next-Generation Sequencing in Diagnostics and Clinical Research.

Authors:
Gerald Hoefler

Pathobiology 2017 12;84(6):289-291. Epub 2017 Dec 12.

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http://dx.doi.org/10.1159/000485366DOI Listing
February 2019

Atypical "hairy cell-like" presentation of leukemic mantle cell lymphoma.

Clin Chem Lab Med 2018 12;57(2):e34-e36

Department of Internal Medicine 1, Hospital of the Brothers of St. John of God, Graz, Austria.

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http://dx.doi.org/10.1515/cclm-2018-0633DOI Listing
December 2018

Early Loss of Forkhead Transcription Factor, O Subgroup, Member 1 Protein in the Development of Pancreatic Ductal Adenocarcinoma.

Pathobiology 2018 18;85(5-6):342-347. Epub 2018 Sep 18.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz,

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http://dx.doi.org/10.1159/000492433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390459PMC
December 2018

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.

Cell Metab 2018 11 16;28(5):706-720.e6. Epub 2018 Aug 16.

Institute of Biochemistry, Graz University of Technology, Humboldtstrasse 46/III, 8010 Graz, Austria; BioTechMed-Graz, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390946PMC
November 2018

Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function.

Free Radic Biol Med 2018 02 27;115:219-231. Epub 2017 Nov 27.

The Heart Research Institute, Sydney, Australia; Dept. of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Sydney, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.11.019DOI Listing
February 2018

Expansion of BCR/ABL1 cells requires PAK2 but not PAK1.

Br J Haematol 2017 10 14;179(2):229-241. Epub 2017 Jul 14.

Institute of Pharmacology and Toxicology, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/bjh.14833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655792PMC
October 2017

Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.

Histochem Cell Biol 2017 Aug 20;148(2):105-115. Epub 2017 Mar 20.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1007/s00418-017-1557-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508037PMC
August 2017

Tumour heterogeneity: principles and practical consequences.

Virchows Arch 2016 Oct 13;469(4):371-84. Epub 2016 Jul 13.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1007/s00428-016-1987-9DOI Listing
October 2016

A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.

Tumour Biol 2016 Jun 15;37(6):7295-303. Epub 2015 Dec 15.

Department of Medical Sciences, University of Trieste, Cattinara Hospital-Surgical Pathology Building, Strada di Fiume 447, 34149, Trieste, Italy.

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http://link.springer.com/content/pdf/10.1007/s13277-015-4543
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http://link.springer.com/10.1007/s13277-015-4543-3
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http://dx.doi.org/10.1007/s13277-015-4543-3DOI Listing
June 2016

Tumor-Induced Hyperlipidemia Contributes to Tumor Growth.

Cell Rep 2016 Apr 31;15(2):336-48. Epub 2016 Mar 31.

Group on Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, AB T6G 2R3, Canada; Department of Pediatrics, University of Alberta, Edmonton, AB T6G 2R3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984953PMC
April 2016

MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.

Mol Carcinog 2015 Nov 25;54(11):1442-50. Epub 2014 Sep 25.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/mc.22218DOI Listing
November 2015

Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia.

Ann Hematol 2015 Nov 25;94(11):1923-4. Epub 2015 Jul 25.

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, 8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00277-015-2445-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024751PMC
November 2015

Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.

Mod Pathol 2015 Jul 13;28(7):895-903. Epub 2015 Mar 13.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/modpathol.2015.39DOI Listing
July 2015

Evaluation of uric acid as a prognostic blood-based marker in a large cohort of pancreatic cancer patients.

PLoS One 2014 18;9(8):e104730. Epub 2014 Aug 18.

Division of Clinical Oncology, Department of Medicine, Medical University of Graz, Graz, Austria; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104730PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136788PMC
May 2015

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients.

Am J Physiol Lung Cell Mol Physiol 2015 May 3;308(10):L1002-13. Epub 2015 Apr 3.

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria; Department of Experimental Anesthesiology, Medical University of Graz, Graz, Austria

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http://dx.doi.org/10.1152/ajplung.00383.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437007PMC
May 2015

Preexisting TP53 mutation in therapy-related acute myeloid leukemia.

Ann Hematol 2015 Mar 20;94(3):527-9. Epub 2014 Aug 20.

Division of Hematology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 38D, A-8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00277-014-2191-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317506PMC
March 2015

Nephroblastomas show low expression of microR-204 and high expression of its target, the oncogenic transcription factor MEIS1.

Pediatr Dev Pathol 2014 May-Jun;17(3):169-75. Epub 2014 Mar 11.

1  Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria.

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http://dx.doi.org/10.2350/13-01-1288-OA.1DOI Listing
September 2014

Megakaryocytic morphology and clinical parameters in essential thrombocythemia, polycythemia vera, and primary myelofibrosis with and without JAK2 V617F.

Arch Pathol Lab Med 2014 Sep;138(9):1203-9

From the Institute of Pathology (Drs Vytrva, Stacher, Regitnig, Hoefler, and Beham-Schmid) and the Division of Hematology, Department of Medicine (Dr Zinke-Cerwenka), Medical University of Graz, Graz, Austria; the Division of Hematology, Department of Medicine, General Hospital Fürstenfeld, Fürstenfeld, Austria (Dr Hojas); the Division of Hematology, Department of Medicine, General Hospital Leoben, Leoben, Austria (Dr Hubmann); and the Department of Pathology, Radiumhemmet (Dr Porwit), and the Division of Hematology, Department of Medicine (Dr Bjorkholm), Karolinska University Hospital, Stockholm, Sweden. Dr Vytrva is now with the Department of Clinical Pathology, Ryhov Hospital, Jönköping, Sweden. Dr Porwit is now with the Department of Laboratory Hematology, General Hospital of Toronto, Toronto, Ontario, Canada. Drs Vytrva and Stacher contributed equally to the study.

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http://dx.doi.org/10.5858/arpa.2013-0018-OADOI Listing
September 2014

Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).

Biochim Biophys Acta 2014 Jul 1;1842(7):959-70. Epub 2014 Mar 1.

Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034162PMC
July 2014

Effects of Lewis lung carcinoma and B16 melanoma on the innervation of the mouse trachea.

Auton Neurosci 2014 Jul 19;183:106-10. Epub 2014 Mar 19.

Institute of Anatomy and Cell Biology, Justus-Liebig-University Giessen, Aulweg 123, 35385 Giessen, Germany; Institute of Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.autneu.2014.03.005DOI Listing
July 2014

Tumor macroenvironment and metabolism.

Semin Oncol 2014 Apr 1;41(2):281-95. Epub 2014 Mar 1.

Institute of Pathology, Medical University of Graz, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2014.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012137PMC
April 2014

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.

Hepatology 2014 Mar 28;59(3):858-69. Epub 2014 Jan 28.

Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria; Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/hep.26732DOI Listing
March 2014

miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.

J Clin Pathol 2014 Mar 4;67(3):198-203. Epub 2013 Oct 4.

Division of Oncology, Department of Internal Medicine, Medical University of Graz (MUG), , Graz, Austria.

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http://dx.doi.org/10.1136/jclinpath-2013-201904DOI Listing
March 2014

Identification of the transcription factor HOXB4 as a novel target of miR-23a.

Genes Chromosomes Cancer 2013 Aug 30;52(8):709-15. Epub 2013 Apr 30.

Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036, Graz, Austria.

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http://dx.doi.org/10.1002/gcc.22066DOI Listing
August 2013

The role of triglyceride lipases in cancer associated cachexia.

Trends Mol Med 2013 May 14;19(5):292-301. Epub 2013 Mar 14.

Institute of Pathology, Medical University of Graz, 8036 Graz, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S14714914130003
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http://dx.doi.org/10.1016/j.molmed.2013.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655383PMC
May 2013

The pluripotent renal stem cell regulator SIX2 is activated in renal neoplasms and influences cellular proliferation and migration.

Hum Pathol 2013 Mar 17;44(3):336-45. Epub 2012 Sep 17.

Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria.

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http://dx.doi.org/10.1016/j.humpath.2012.05.021DOI Listing
March 2013

The role of morphology in combination with ploidy analysis in characterizing early gestational abortion.

Virchows Arch 2013 Feb 21;462(2):175-82. Epub 2012 Dec 21.

Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A-8036 Graz, Austria.

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http://dx.doi.org/10.1007/s00428-012-1350-8DOI Listing
February 2013

Histiocytic sarcoma - targeted therapy: novel therapeutic options? A series of 4 cases.

Onkologie 2012 12;35(7-8):447-50. Epub 2012 Jul 12.

Department of Internal Medicine, Division of Hematooncology, Paracelsus Medical University of Salzburg, Austria.

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http://dx.doi.org/10.1159/000340066DOI Listing
January 2013

Comparison of the 2002 and 2010 TNM classification systems regarding outcome prediction in clear cell and papillary renal cell carcinoma.

Histopathology 2013 Jan 28;62(2):237-46. Epub 2012 Sep 28.

Division of Oncology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 25, Graz, Austria.

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http://doi.wiley.com/10.1111/his.12001
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http://dx.doi.org/10.1111/his.12001DOI Listing
January 2013

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.

J Hepatol 2012 Nov 28;57(5):1061-8. Epub 2012 Jun 28.

Institute of Molecular Biology and Biochemistry, Medical University of Graz, Austria.

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http://dx.doi.org/10.1016/j.jhep.2012.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477492PMC
November 2012

Cancer cachexia alters intracellular surfactant metabolism but not total alveolar surface area.

Histochem Cell Biol 2012 Nov 19;138(5):803-13. Epub 2012 Jul 19.

Institute of Anatomy and Cell Biology, Justus-Liebig-University Giessen, Aulweg 123, 35385, Giessen, Germany.

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http://dx.doi.org/10.1007/s00418-012-0995-3DOI Listing
November 2012

Trends of stage, grade, histology and tumour necrosis in renal cell carcinoma in a European centre surgical series from 1984 to 2010.

J Clin Pathol 2012 Aug 25;65(8):721-4. Epub 2012 May 25.

Division of Oncology, Department of Internal Medicine, Medical University of Graz (MUG), Graz, Austria.

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http://dx.doi.org/10.1136/jclinpath-2012-200797DOI Listing
August 2012

miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.

Carcinogenesis 2012 May 19;33(5):1014-21. Epub 2012 Mar 19.

Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria.

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http://dx.doi.org/10.1093/carcin/bgs126DOI Listing
May 2012

Cardiac fibrosis in human transplanted hearts is mainly driven by cells of intracardiac origin.

J Am Coll Cardiol 2012 Mar;59(11):1008-16

Division of Oncology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz, Austria.

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http://dx.doi.org/10.1016/j.jacc.2011.11.036DOI Listing
March 2012

Lim1, an embryonal transcription factor, is absent in multicystic renal dysplasia, but reactivated in nephroblastomas.

Pathobiology 2011 19;78(4):210-9. Epub 2011 Jul 19.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1159/000326769DOI Listing
November 2011

Gastric cancer and concomitant renal cancer: a systematic immunohistochemical and molecular analysis.

Oncol Rep 2011 Sep 15;26(3):567-75. Epub 2011 Jun 15.

Institute of Pathology, Medical University of Graz, 8036 Graz, Austria.

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http://dx.doi.org/10.3892/or.2011.1346DOI Listing
September 2011

Loss of PTEN/MMAC1 activity is a rare and late event in the pathogenesis of nephroblastomas.

Hum Pathol 2010 Aug 8;41(8):1172-7. Epub 2010 Apr 8.

Department of Pathology, General Hospital and Paracelsus Medical University Salzburg, Muellner Hauptstrasse 48, A-5020 Salzburg, Austria.

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http://dx.doi.org/10.1016/j.humpath.2009.10.024DOI Listing
August 2010

Quantitative short-tandem repeat analysis of recipient-derived cells as an additional tool for diagnosing cardiac allograft rejection.

Transplantation 2010 Mar;89(6):749-55

Department of Oncology, University Clinic of Internal Medicine, Medical University of Graz, Graz, Austria.

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https://insights.ovid.com/crossref?an=00007890-201003270-000
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http://dx.doi.org/10.1097/TP.0b013e3181cab05cDOI Listing
March 2010