Ger H Koek

Ger H Koek

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Ger H Koek

Publications by authors named "Ger H Koek"

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Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients.

Diagnostics (Basel) 2019 Jun 21;9(2). Epub 2019 Jun 21.

Department of Medicine III, RWTH-University Hospital Aachen, D-52074 Aachen, Germany.

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http://dx.doi.org/10.3390/diagnostics9020063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628070PMC
June 2019

The influence of ethnicity on disease outcome in patients with chronic hepatitis B infection.

J Med Virol 2019 Apr 28;91(4):623-629. Epub 2018 Nov 28.

School of Nutrition and Translational Research in Metabolism, University Maastricht, Maastricht, The Netherlands.

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http://doi.wiley.com/10.1002/jmv.25353
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http://dx.doi.org/10.1002/jmv.25353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587848PMC
April 2019

Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease.

Hepatol Commun 2019 Apr 11;3(4):587-596. Epub 2019 Feb 11.

Cardiovascular Research Institute Maastricht, Maastricht University Maastricht the Netherlands.

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http://doi.wiley.com/10.1002/hep4.1319
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http://dx.doi.org/10.1002/hep4.1319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442707PMC
April 2019

Visfatin Serum Levels Predict Mortality in Critically Ill Patients.

Dis Markers 2018 26;2018:7315356. Epub 2018 Aug 26.

Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1155/2018/7315356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129328PMC
January 2019

Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury.

J Pathol 2019 Jan 11;247(1):110-122. Epub 2018 Dec 11.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/path.5174DOI Listing
January 2019

Clinical relevance of copeptin plasma levels as a biomarker of disease severity and mortality in critically ill patients.

J Clin Lab Anal 2018 Nov 5;32(9):e22614. Epub 2018 Jul 5.

Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/jcla.22614DOI Listing
November 2018

High mobility group box 1 as a biomarker in critically ill patients.

J Clin Lab Anal 2018 Oct 3;32(8):e22584. Epub 2018 Jun 3.

Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany.

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http://doi.wiley.com/10.1002/jcla.22584
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http://dx.doi.org/10.1002/jcla.22584DOI Listing
October 2018

Reply.

Clin Gastroenterol Hepatol 2018 04 16;16(4):596-597. Epub 2017 Dec 16.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University, Medical Centre, School of Nutrition and Translational Research in Metabolism, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.cgh.2017.12.023DOI Listing
April 2018

The potential of flavonoids in the treatment of non-alcoholic fatty liver disease.

Crit Rev Food Sci Nutr 2017 Mar;57(4):834-855

a Department of Toxicology , Maastricht University , Maastricht , The Netherlands.

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http://dx.doi.org/10.1080/10408398.2014.952399DOI Listing
March 2017

PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease.

Gastroenterology 2017 03 1;152(4):912-913. Epub 2017 Feb 1.

Department of Internal Medicine, Division of Endocrinology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163553
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http://dx.doi.org/10.1053/j.gastro.2016.12.020DOI Listing
March 2017

Review of familial cerebral cavernous malformations and report of seven additional families.

Am J Med Genet A 2017 Feb 28;173(2):338-351. Epub 2016 Oct 28.

Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1002/ajmg.a.38028DOI Listing
February 2017

Is intestinal oxidative stress involved in patients with compensated liver cirrhosis?

Ann Hepatol 2016 May-Jun;15(3):402-9

Division Gastroenterology-Hepatology, Department of Internal Medicine, Maastricht University Medical Center, the Netherlands; School for Nutrition, Toxicology and Metabolism (NUTRIM), Maastricht University Medical Center, the Netherlands.

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http://dx.doi.org/10.5604/16652681.1198816DOI Listing
January 2017

Course of iron parameters in HFE-hemochromatosis patients during initial treatment with erythrocytapheresis compared to phlebotomy.

J Clin Apher 2016 Dec 16;31(6):564-570. Epub 2016 Feb 16.

Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/jca.21451DOI Listing
December 2016

How we manage patients with hereditary haemochromatosis.

Br J Haematol 2016 Dec 10;175(5):759-770. Epub 2016 Oct 10.

Division of Gastroenterology & Hepatology, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.

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http://dx.doi.org/10.1111/bjh.14376DOI Listing
December 2016

Response to can modifier gene mutations improve the predictive value of the modified Iron Avidity Index in Type 1 Hereditary Haemochromatosis?

Liver Int 2016 11;36(11):1714

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1111/liv.13169DOI Listing
November 2016

Adherence to ribavirin in chronic hepatitis C patients on antiviral treatment: Results from a randomized controlled trial using real-time medication monitoring.

Clin Res Hepatol Gastroenterol 2016 Nov 8;40(5):622-630. Epub 2016 Feb 8.

Department of Gastroenterology and Hepatology, University Medical Center of Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2015.12.014DOI Listing
November 2016

The modified iron avidity index: a promising phenotypic predictor in HFE-related haemochromatosis.

Liver Int 2016 10 6;36(10):1535-9. Epub 2016 Apr 6.

Maastricht University Medical Center, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht, the Netherlands.

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http://dx.doi.org/10.1111/liv.13121DOI Listing
October 2016

Plasma IL-1 receptor antagonist levels correlate with the development of non-alcoholic steatohepatitis.

Biomark Med 2015 19;9(12):1301-9. Epub 2015 Nov 19.

Departments of Molecular Genetics, Molecular Cell Biology & Population Genetics, Nutrition & Toxicology Research (NUTRIM) Institutes of Maastricht, University of Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.2217/bmm.15.71DOI Listing
September 2016

Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease.

BMC Med 2016 07 22;14(1):107. Epub 2016 Jul 22.

Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.

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http://dx.doi.org/10.1186/s12916-016-0652-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957359PMC
July 2016

Proton Pump Inhibitors Reduce the Frequency of Phlebotomy in Patients With Hereditary Hemochromatosis.

Clin Gastroenterol Hepatol 2016 Jan 1;14(1):147-52. Epub 2015 Aug 1.

Division of Gastroenterology and Hepatology and NUTRIM School for Nutrition, Toxicology and Metabolism Research, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.cgh.2015.06.043DOI Listing
January 2016

A profile of volatile organic compounds in exhaled air as a potential non-invasive biomarker for liver cirrhosis.

Sci Rep 2016 Jan 29;6:19903. Epub 2016 Jan 29.

Department of Pharmacology and Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Center, the Netherlands.

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http://dx.doi.org/10.1038/srep19903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731784PMC
January 2016

Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology.

PLoS One 2014 23;9(12):e115922. Epub 2014 Dec 23.

Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115922PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275274PMC
December 2015

Once-daily dose regimen of ribavirin is interchangeable with a twice-daily dose regimen: randomized open clinical trial.

Pharmgenomics Pers Med 2015 12;8:137-44. Epub 2015 Aug 12.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Centre, Maastricht, the Netherlands.

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http://dx.doi.org/10.2147/PGPM.S82782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593207PMC
October 2015

Is intestinal oxidative stress involved in patients with compensated liver cirrhosis?

Ann Hepatol 2016 May - Jun;15(3):402-409

Division Gastroenterology-Hepatology, Department of Internal Medicine, Maastricht University Medical Center, the Netherlands; School for Nutrition, Toxicology and Metabolism (NUTRIM), Maastricht University Medical Center, the Netherlands.

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http://dx.doi.org/10.5604/16652681.1198816DOI Listing
June 2015

Randomized controlled trial of transoral incisionless fundoplication vs. proton pump inhibitors for treatment of gastroesophageal reflux disease.

Am J Gastroenterol 2015 Apr 31;110(4):531-42. Epub 2015 Mar 31.

Department of Surgery, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.

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http://dx.doi.org/10.1038/ajg.2015.28DOI Listing
April 2015

The flavonoid monoHER promotes the adaption to oxidative stress during the onset of NAFLD.

Biochem Biophys Res Commun 2015 Jan 22;456(1):179-82. Epub 2014 Nov 22.

Department of Toxicology, Faculty of Health, Medicine and Life Sciences, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.11.055DOI Listing
January 2015

Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.

PLoS One 2013 2;8(12):e78792. Epub 2013 Dec 2.

Departments of Molecular Genetics, Electron Microscopy and Internal Medicine, Nutrition and Toxicology Research (NUTRIM) Institute of Maastricht and Maastricht University Medical Centre (MUMC), Maastricht University, Maastricht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078792PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846469PMC
August 2014

Perihepatic adhesions: an unusual complication of hemolysis, elevated liver enzymes and low platelet syndrome.

World J Gastroenterol 2014 Jul;20(26):8726-8

Margot M Koeneman, Louis L Peeters, Department of Obstetrics and Gynecology, Maastricht University Medical Center, 6202 AZ Maastricht, The Netherlands.

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http://dx.doi.org/10.3748/wjg.v20.i26.8726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093727PMC
July 2014

End-stage cardiomyopathy because of hereditary hemochromatosis successfully treated with erythrocytapheresis in combination with left ventricular assist device support.

Circ Heart Fail 2014 May;7(3):541-3

From the Blood Bank Division, Unit Transfusion Medicine, Sanquin Blood Supply, Maastricht, The Netherlands (E.R.-S.); Department of Cardiology (N.D.J., C.K.), Department of Hematology (K.P.M.v.G.), and Department of Pathology (A.V.), University Medical Center Utrecht, Utrecht, The Netherlands; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University Medical Center Maastricht, Maastricht, The Netherlands (E.R.-S., G.H.K.); Faculty of Medicine, Masaryk University, Brno, Czech Republic (K.M.); Department of Cardiology (E.M.C.J.W.) and Department of Internal Medicine (W.M.S.), Medical Spectrum Twente, Enschede, The Netherlands; and Blood Bank Division, Unit Transfusion Medicine, Sanquin Blood Supply, Groningen, The Netherlands (C.v.B.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001198DOI Listing
May 2014

Critical appraisal of 13C breath tests for microsomal liver function: aminopyrine revisited.

Liver Int 2014 Apr 16;34(4):487-94. Epub 2014 Jan 16.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.1111/liv.12451DOI Listing
April 2014

Superoxide anion radicals activate hepatic stellate cells after entry through chloride channels: a new target in liver fibrosis.

Eur J Pharmacol 2014 Feb 28;724:140-4. Epub 2013 Dec 28.

Maastricht University, Faculty of Health, Medicine and Life Sciences, Department of Toxicology, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.ejphar.2013.12.033DOI Listing
February 2014

Large intestine permeability is increased in patients with compensated liver cirrhosis.

Am J Physiol Gastrointest Liver Physiol 2014 Jan 21;306(2):G147-53. Epub 2013 Nov 21.

Div. of Gastroenterology-Hepatology, Dept. of Internal Medicine, Maastricht Univ. Medical Center, PO Box 5800, 6202 AZ Maastricht, the Netherlands.

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http://dx.doi.org/10.1152/ajpgi.00330.2013DOI Listing
January 2014

Intestinal epithelial barrier function in liver cirrhosis: an extensive review of the literature.

Liver Int 2013 Nov 23;33(10):1457-69. Epub 2013 Jul 23.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands; School for Nutrition, Toxicology and Metabolism (NUTRIM), Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.1111/liv.12271DOI Listing
November 2013

Endoscopic duodenal-jejunal bypass liner rapidly improves plasma parameters of nonalcoholic fatty liver disease.

Clin Gastroenterol Hepatol 2013 Nov 3;11(11):1517-20. Epub 2013 Aug 3.

Department of General Surgery and NUTRIM School for Nutrition, Toxicology and Metabolism Research, Maastricht University Medical Center, Maastricht, the Netherlands; Department of General Surgery, Atrium Medical Center Parkstad, Heerlen, the Netherlands.

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http://dx.doi.org/10.1016/j.cgh.2013.07.029DOI Listing
November 2013

Revisional laparoscopic antireflux surgery after unsuccessful endoscopic fundoplication.

Surg Endosc 2013 Jun 5;27(6):2231-6. Epub 2013 Jan 5.

Department of General Surgery, Maastricht University Medical Center, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00464-012-2685-6DOI Listing
June 2013

Non-alcoholic steatohepatitis: the role of oxidized low-density lipoproteins.

J Hepatol 2013 Apr 23;58(4):801-10. Epub 2012 Nov 23.

Department of Molecular Genetics, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2012.11.014DOI Listing
April 2013

Transoral incisionless fundoplication for treatment of gastroesophageal reflux disease in clinical practice.

Surg Endosc 2012 Nov 31;26(11):3307-15. Epub 2012 May 31.

Department of General Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00464-012-2324-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472060PMC
November 2012

Ribavirin-induced externalization of phosphatidylserine in erythrocytes is predominantly caused by inhibition of aminophospholipid translocase activity.

Eur J Pharmacol 2012 Oct 21;693(1-3):1-6. Epub 2012 Aug 21.

Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, The Netherlands.

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http://dx.doi.org/10.1016/j.ejphar.2012.07.041DOI Listing
October 2012

Therapeutic approach of hepatic sarcoidosis.

Curr Opin Pulm Med 2012 Sep;18(5):472-82

Department of Internal Medicine, Atrium Medical Centre, Heerlen, The Netherlands.

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http://www.ildcare.nl/wp-content/uploads/2014/06/PS-AC-h5.pd
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MCP.0b013e3283541626DOI Listing
September 2012

[Erythrocytapheresis for hereditary haemochromatosis].

Ned Tijdschr Geneeskd 2012 ;156(26):A4745

Sanquin Bloedbank, unit klinisch consultatieve dienst, Maastricht, the Netherlands.

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September 2012

An update on less invasive and endoscopic techniques mimicking the effect of bariatric surgery.

J Obes 2012 21;2012:597871. Epub 2012 Aug 21.

Department of General Surgery, Maastricht University Medical Centre, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands.

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http://dx.doi.org/10.1155/2012/597871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432381PMC
September 2012

Hepatic sinusoidal obstruction syndrome (SOS) reduces the effect of oxaliplatin in colorectal liver metastases.

Histopathology 2012 Aug 9;61(2):314-8. Epub 2012 May 9.

Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04208.xDOI Listing
August 2012

Bortezomib-associated fatal liver failure in a haemodialysis patient with multiple myeloma.

Clin Toxicol (Phila) 2012 Jun 2;50(5):444-5. Epub 2012 Apr 2.

Division of Nephrology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.3109/15563650.2012.673624DOI Listing
June 2012

[EndoBarrier for counteracting obesity and metabolic syndrome].

Ned Tijdschr Geneeskd 2012 ;156(13):A3844

Maastricht Universitair Medisch Centrum, afd. Chirurgie, Maastricht, The Netherlands.

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May 2012

[Treatment of non-alcoholic fatty liver disease].

Authors:
Ger H Koek

Ned Tijdschr Geneeskd 2011 ;155:A3181

Maastricht Universitair Medisch Centrum, afd. Interne geneeskunde, Divisie maag-, darm-, leverziekten, Maastricht, the Netherlands.

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October 2011

Depressive symptoms following interferon-α therapy: mediated by immune-induced reductions in brain-derived neurotrophic factor?

Int J Neuropsychopharmacol 2011 Mar 29;14(2):247-53. Epub 2010 Jul 29.

Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands.

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https://academic.oup.com/ijnp/article-lookup/doi/10.1017/S14
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http://dx.doi.org/10.1017/S1461145710000830DOI Listing
March 2011

To do or not to do: IVF and ICSI in chronic hepatitis B virus carriers.

Hum Reprod 2009 Nov 22;24(11):2676-8. Epub 2009 Jul 22.

Department of Medical Microbiology, Research Institute Growth & Development (GROW), Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands.

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http://dx.doi.org/10.1093/humrep/dep258DOI Listing
November 2009

Will skepticism stop the evolution of endoscopic GERD treatment?

Eur J Gastroenterol Hepatol 2009 Oct;21(10):1222-4

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http://dx.doi.org/10.1097/MEG.0b013e32832dd7e6DOI Listing
October 2009

Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER.

Free Radic Biol Med 2009 Jun 9;46(12):1567-73. Epub 2009 Mar 9.

Department of Pharmacology and Toxicology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, 6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.freeradbiomed.2009.02.031DOI Listing
June 2009

Decreased hepatosplanchnic antioxidant uptake during hepatic ischaemia/reperfusion in patients undergoing liver resection.

Clin Sci (Lond) 2008 Apr;114(8):553-60

Department of Surgery, University Hospital Maastricht & Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, 6200 AZ Maastricht, The Netherlands.

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http://dx.doi.org/10.1042/CS20070317DOI Listing
April 2008

Therapeutic erythrocytapheresis versus phlebotomy in the initial treatment of hereditary hemochromatosis - A pilot study.

Transfus Apher Sci 2007 Jun 13;36(3):261-7. Epub 2007 Jun 13.

Sanquin Blood Bank Southeast Region, Geatano Martinolaan 95, 6229 GS Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.transci.2007.03.005DOI Listing
June 2007

Interferon-alpha-induced depressive symptoms are related to changes in the cytokine network but not to cortisol.

J Psychosom Res 2007 Feb;62(2):207-14

Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, The Netherlands.

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http://dx.doi.org/10.1016/j.jpsychores.2006.09.007DOI Listing
February 2007

Human intestinal spirochaetosis: any clinical significance?

Eur J Gastroenterol Hepatol 2004 Jan;16(1):83-7

Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/00042737-200401000-00013DOI Listing
January 2004

Hyperemesis gravidarum and severe liver enzyme elevation.

J Hepatol 2002 Jul;37(1):162-3

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http://dx.doi.org/10.1016/s0168-8278(02)00089-2DOI Listing
July 2002