Georgii A Bazykin

Georgii A Bazykin

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Georgii A Bazykin

Georgii A Bazykin

Publications by authors named "Georgii A Bazykin"

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Allele-specific nonstationarity in evolution of influenza A virus surface proteins.

Proc Natl Acad Sci U S A 2019 Oct 2;116(42):21104-21112. Epub 2019 Oct 2.

Center of Life Sciences, Skolkovo Institute of Science and Technology, Skolkovo, 143028 Russia;

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http://dx.doi.org/10.1073/pnas.1904246116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800338PMC
October 2019

Architecture of Parallel Adaptation in Ten Lacustrine Threespine Stickleback Populations from the White Sea Area.

Genome Biol Evol 2019 09;11(9):2605-2618

Laboratory of Molecular Genetics, Russian Federal Research Institute of Fisheries and Oceanography, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evz175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761963PMC
September 2019

Matching population diversity of rhizobial A and legume genes in plant-microbe symbiosis.

Ecol Evol 2019 Sep 30;9(18):10377-10386. Epub 2019 Aug 30.

ARRIAM, All-Russia Research Institute for Agricultural Microbiology Pushkin Russia.

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http://dx.doi.org/10.1002/ece3.5556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787799PMC
September 2019

Bursts of amino acid replacements in protein evolution.

R Soc Open Sci 2019 Mar 27;6(3):181095. Epub 2019 Mar 27.

Department of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University, Moscow 119234, Russia.

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http://dx.doi.org/10.1098/rsos.181095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458383PMC
March 2019

Are Nonsense Alleles of Drosophila melanogaster Genes under Any Selection?

Genome Biol Evol 2018 04;10(4):1012-1018

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evy032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888714PMC
April 2018

Prevalence of loss-of-function alleles does not correlate with lifetime fecundity and other life-history traits in metazoans.

Biol Direct 2018 03 2;13(1). Epub 2018 Mar 2.

Laboratory of Evolutionary Genomics, A.N. Belozersky Institute of Physico-Chemical Biology of Lomonosov Moscow State Universit, Moscow, 119992, Russia.

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http://dx.doi.org/10.1186/s13062-018-0206-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834895PMC
March 2018

Substitutions into amino acids that are pathogenic in human mitochondrial proteins are more frequent in lineages closely related to human than in distant lineages.

PeerJ 2017 12;5:e4143. Epub 2017 Dec 12.

Sector of Molecular Evolution, Institute for Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russian Federation.

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http://dx.doi.org/10.7717/peerj.4143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731343PMC
December 2017

Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.

Genome Res 2017 08 16;27(8):1336-1343. Epub 2017 May 16.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow 127994, Russia.

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http://dx.doi.org/10.1101/gr.219915.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538550PMC
August 2017

Evolution of Local Mutation Rate and Its Determinants.

Mol Biol Evol 2017 05;34(5):1100-1109

Sector for Molecular Evolution, Institute for Information Transmission Problems of the RAS (Kharkevich Institute), Moscow, Russia.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msx060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850301PMC
May 2017

Parallel Evolution of Metazoan Mitochondrial Proteins.

Genome Biol Evol 2017 05;9(5):1341-1350

Institute for Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evx025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520408PMC
May 2017

APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.

Genome Res 2017 02 9;27(2):175-184. Epub 2016 Dec 9.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow 127994, Russia.

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http://dx.doi.org/10.1101/gr.210336.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287224PMC
February 2017

Compensatory Evolution of Intrinsic Transcription Terminators in Bacillus Cereus.

Genome Biol Evol 2017 02;9(2):340-349

Sector for Molecular Evolution, Institute of Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evw295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381666PMC
February 2017

Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data.

Genome Biol Evol 2016 07 2;8(6):1971-9. Epub 2016 Jul 2.

Institute for Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russia Skolkovo Institute of Science and Technology, Skolkovo, Russia Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Russia Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Russia Pirogov Russian National Research Medical University, Moscow, Russia

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https://academic.oup.com/gbe/article-lookup/doi/10.1093/gbe/
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http://dx.doi.org/10.1093/gbe/evw137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943204PMC
July 2016

Fitness Consequences of Advanced Ancestral Age over Three Generations in Humans.

PLoS One 2015 1;10(6):e0128197. Epub 2015 Jun 1.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Bolshoy Karetny pereulok 19, Moscow, 127994, Russia; Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Vorbyevy Gory 1-73, Moscow, 119992, Russia; Belozersky Institute for Physical and Chemical Biology, Lomonosov Moscow State University, Vorbyevy Gory 1-40, Moscow, 119992, Russia; Pirogov Russian National Research Medical University, Ul. Ostrovityanova 1, Moscow, 117997, Russia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128197PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451146PMC
February 2016

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.

Genome Res 2016 Feb 11;26(2):174-82. Epub 2016 Jan 11.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland; Service of Genetic Medicine, University Hospitals of Geneva, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1101/gr.197046.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728370PMC
February 2016

Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.

Mol Biol Evol 2015 Dec 15;32(12):3158-72. Epub 2015 Sep 15.

Institute of Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russia Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia

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http://dx.doi.org/10.1093/molbev/msv184DOI Listing
December 2015

Extraordinary Genetic Diversity in a Wood Decay Mushroom.

Mol Biol Evol 2015 Oct 10;32(10):2775-83. Epub 2015 Jul 10.

School of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia Department of Ecology and Evolutionary Biology, University of Michigan

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http://dx.doi.org/10.1093/molbev/msv153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576712PMC
October 2015

Changing preferences: deformation of single position amino acid fitness landscapes and evolution of proteins.

Biol Lett 2015 Oct;11(10)

Institute for Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow 127051, Russia Faculty of Bioengineering and Bioinformatics and Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119234, Russia Pirogov Russian National Research Medical University, Moscow 117997, Russia

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http://dx.doi.org/10.1098/rsbl.2015.0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650171PMC
October 2015

Coordinated Evolution of Influenza A Surface Proteins.

PLoS Genet 2015 Aug 6;11(8):e1005404. Epub 2015 Aug 6.

Institute for Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russia; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia; Pirogov Russian National Research Medical University, Moscow, Russia.

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http://dx.doi.org/10.1371/journal.pgen.1005404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527594PMC
August 2015

Gene age predicts the strength of purifying selection acting on gene expression variation in humans.

Am J Hum Genet 2014 Dec;95(6):660-74

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 Rue Michel-Servet, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259975PMC
December 2014

Fast evolution from precast bricks: genomics of young freshwater populations of threespine stickleback Gasterosteus aculeatus.

PLoS Genet 2014 Oct 9;10(10):e1004696. Epub 2014 Oct 9.

Laboratory of Molecular genetics, Russian Institute of Fisheries and Oceanology, Russian Federal Research Institute of Fisheries and Oceanography, Moscow, Russia; N. K. Koltsov Institute of Developmental Biology RAS, Moscow, Russia.

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http://dx.doi.org/10.1371/journal.pgen.1004696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191950PMC
October 2014

Weak negative and positive selection and the drift load at splice sites.

Genome Biol Evol 2014 May 14;6(6):1437-47. Epub 2014 May 14.

Faculty of Bioengineering and Bioinformatics, M.V. Lomonosov Moscow State University, Moscow, RussiaLife Sciences Institute and Department of Ecology and Evolutionary Biology, University of Michigan.

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http://dx.doi.org/10.1093/gbe/evu100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079205PMC
May 2014

Intrasubtype reassortments cause adaptive amino acid replacements in H3N2 influenza genes.

PLoS Genet 2014 Jan 9;10(1):e1004037. Epub 2014 Jan 9.

Department of Bioengineering and Bioinformatics, M.V. Lomonosov Moscow State University, Moscow, Russia ; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, Russia.

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http://dx.doi.org/10.1371/journal.pgen.1004037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886890PMC
January 2014

Functional implications of splicing polymorphisms in the human genome.

Hum Mol Genet 2013 Sep 2;22(17):3449-59. Epub 2013 May 2.

Institute for Information Transmission Problems (Kharkevich Institute), Russian Academy of Sciences, Moscow 127994, Russia.

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http://dx.doi.org/10.1093/hmg/ddt200DOI Listing
September 2013

Short indels are subject to insertion-biased gene conversion.

Evolution 2013 Sep 11;67(9):2604-13. Epub 2013 May 11.

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskye Gory 1-73, Moscow, 119992, Russia; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Bolshoi Karetny pereulok, 19, Moscow, 127994, Russia.

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http://dx.doi.org/10.1111/evo.12129DOI Listing
September 2013

Strong mutational bias toward deletions in the Drosophila melanogaster genome is compensated by selection.

Genome Biol Evol 2013 ;5(3):514-24

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evt021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622295PMC
August 2013

Prevalence of multinucleotide replacements in evolution of primates and Drosophila.

Mol Biol Evol 2013 Jun 27;30(6):1315-25. Epub 2013 Feb 27.

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/molbev/mst036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649671PMC
June 2013

Genome-Level Analysis of Selective Constraint without Apparent Sequence Conservation.

Genome Biol Evol 2013 ;5(3):532-41

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evt023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622294PMC
March 2013

Fitness conferred by replaced amino acids declines with time.

Biol Lett 2012 Oct 23;8(5):825-8. Epub 2012 May 23.

Institute for Information Transmission Problems, Russian Academy of Sciences, Bolshoi Karetny per. 19, Moscow 127994, Russia.

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http://dx.doi.org/10.1098/rsbl.2012.0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440982PMC
October 2012

Major role of positive selection in the evolution of conservative segments of Drosophila proteins.

Proc Biol Sci 2012 Sep 6;279(1742):3409-17. Epub 2012 Jun 6.

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Vorbyevy Gory 1-73, Moscow 119992, Russia.

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http://dx.doi.org/10.1098/rspb.2012.0776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396909PMC
September 2012

Heterogeneity of the transition/transversion ratio in Drosophila and Hominidae genomes.

Mol Biol Evol 2012 Aug 15;29(8):1943-55. Epub 2012 Feb 15.

Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/molbev/mss071DOI Listing
August 2012

Insertions and deletions trigger adaptive walks in Drosophila proteins.

Proc Biol Sci 2012 Aug 28;279(1740):3075-82. Epub 2012 Mar 28.

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskye Gory 1-73, Moscow 119991, Russia.

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http://dx.doi.org/10.1098/rspb.2011.2571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385466PMC
August 2012

Detecting past positive selection through ongoing negative selection.

Genome Biol Evol 2011 22;3:1006-13. Epub 2011 Aug 22.

Department of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/gbe/evr086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184776PMC
January 2012

Evolution of prokaryotic genes by shift of stop codons.

J Mol Evol 2011 Feb 17;72(2):138-46. Epub 2010 Nov 17.

Department of Bioengineering and Bioinformatics, M.V. Lomonosov Moscow State University, Vorbyevy Gory 1-73, Moscow 119992, Russia.

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http://dx.doi.org/10.1007/s00239-010-9408-1DOI Listing
February 2011

Prevalence of epistasis in the evolution of influenza A surface proteins.

PLoS Genet 2011 Feb 17;7(2):e1001301. Epub 2011 Feb 17.

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1371/journal.pgen.1001301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040651PMC
February 2011

Alternative translation start sites are conserved in eukaryotic genomes.

Nucleic Acids Res 2011 Jan 22;39(2):567-77. Epub 2010 Sep 22.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, Russia.

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http://dx.doi.org/10.1093/nar/gkq806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025576PMC
January 2011

Young proteins experience more variable selection pressures than old proteins.

Genome Res 2010 Nov 4;20(11):1574-81. Epub 2010 Oct 4.

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gr.109595.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963820PMC
November 2010

Polymorphism due to multiple amino acid substitutions at a codon site within Ciona savignyi.

Genetics 2009 Feb 15;181(2):685-90. Epub 2008 Dec 15.

Life Sciences Institute and Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109-2216.

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http://dx.doi.org/10.1534/genetics.108.097535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644956PMC
February 2009

Directionality in the evolution of influenza A haemagglutinin.

Proc Biol Sci 2008 Nov;275(1650):2455-64

Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1098/rspb.2008.0521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603193PMC
November 2008

Natural selection for nucleotide usage at synonymous and nonsynonymous sites in influenza A virus genes.

J Virol 2008 May 5;82(10):4938-45. Epub 2008 Mar 5.

Program in Applied and Computational Mathematics, Princeton University, Princeton, New Jersey, USA.

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http://dx.doi.org/10.1128/JVI.02415-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346729PMC
May 2008

Extensive parallelism in protein evolution.

Biol Direct 2007 Aug 16;2:20. Epub 2007 Aug 16.

Life Sciences Institute and Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109-2216, USA.

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http://dx.doi.org/10.1186/1745-6150-2-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020468PMC
August 2007

Bursts of nonsynonymous substitutions in HIV-1 evolution reveal instances of positive selection at conservative protein sites.

Proc Natl Acad Sci U S A 2006 Dec 12;103(51):19396-401. Epub 2006 Dec 12.

Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1073/pnas.0609484103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698441PMC
December 2006

Comparative genomics of transcriptional regulation in yeasts and its application to identification of a candidate alpha-isopropylmalate transporter.

J Bioinform Comput Biol 2006 Oct;4(5):981-98

Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1142/s0219720006002284DOI Listing
October 2006

Rate of promoter class turn-over in yeast evolution.

BMC Evol Biol 2006 Feb 10;6:14. Epub 2006 Feb 10.

Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA.

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http://dx.doi.org/10.1186/1471-2148-6-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1457003PMC
February 2006

Positive selection at sites of multiple amino acid replacements since rat-mouse divergence.

Nature 2004 Jun;429(6991):558-62

Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA.

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http://dx.doi.org/10.1038/nature02601DOI Listing
June 2004