George W Sledge

George W Sledge

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George W Sledge

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Patient familiarity with, understanding of, and preferences for clinical trial endpoints and terminology.

Cancer 2020 Apr 22;126(8):1605-1613. Epub 2020 Jan 22.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1002/cncr.32730DOI Listing
April 2020

Gold Nanobipyramids as Second Near Infrared Optical Coherence Tomography Contrast Agents for Multiplexing Studies.

Nano Lett 2020 Jan 10;20(1):101-108. Epub 2019 Oct 10.

Department of Structural Biology , Stanford University , Stanford , California 94305 , United States.

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http://dx.doi.org/10.1021/acs.nanolett.9b03344DOI Listing
January 2020

Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer.

N Engl J Med 2019 06 3;380(25):2395-2405. Epub 2019 Jun 3.

From Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); University of Texas, San Antonio (P.M.R.); Sunnybrook Research Institute, Toronto (K.I.P.), and McMaster University, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Medical Center, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), and Duke University Medical Center, Durham (J.A.O., J.A.) - both in North Carolina; Mayo Clinic, Jacksonville, FL (M.P.G.); National Institutes of Health, National Cancer Institute, Bethesda, MD (T.L.); Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.), Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Washington University, St. Louis (M.J.E.); the National Surgical Adjuvant Breast and Bowel Project Pathology Office (S.P.) and the University of Pittsburgh (A.M.B.), Pittsburgh; Emory University, Atlanta (W.C.W.); Cancer Trials Ireland, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); and the University of Hawaii Cancer Center, Honolulu (J.L.B.).

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http://dx.doi.org/10.1056/NEJMoa1904819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709671PMC
June 2019

Real-Time Detection of Circulating Tumor Cells in Living Animals Using Functionalized Large Gold Nanorods.

Nano Lett 2019 04 29;19(4):2334-2342. Epub 2019 Mar 29.

Department of Structural Biology , Stanford University , Stanford , California 94305 , United States.

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http://dx.doi.org/10.1021/acs.nanolett.8b05005DOI Listing
April 2019

Patients and Physicians in the Era of Modern Cancer Care.

Authors:
George W Sledge

JAMA 2019 Mar;321(9):829-830

Stanford University School of Medicine, Stanford, California.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.17334DOI Listing
March 2019

Targeting CXCR4-induced desmoplasia to improve checkpoint inhibition in breast cancer.

Authors:
George W Sledge

Proc Natl Acad Sci U S A 2019 03 22;116(11):4769-4771. Epub 2019 Feb 22.

Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1900368116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421464PMC
March 2019

Double-Blind Phase III Trial of Adjuvant Chemotherapy With and Without Bevacizumab in Patients With Lymph Node-Positive and High-Risk Lymph Node-Negative Breast Cancer (E5103).

J Clin Oncol 2018 09 24;36(25):2621-2629. Epub 2018 Jul 24.

Kathy D. Miller, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN; Anne O'Neill, Dana-Farber Cancer Institute, Boston, MA; William Gradishar, Northwestern University, Chicago; Nguyet Anh Le-Lindqwister, Heartland Cancer Research National Cancer Institute Community Oncology Research Program, Peoria, IL; Timothy J. Hobday, Mayo Clinic, Rochester; Stuart Bloom, Abbott Northwestern Hospital, Minneapolis, MN; Lori J. Goldstein, Fox Chase Cancer Center, Philadelphia; Adam M. Brufsky, University of Pittsburgh, Pittsburgh, PA; Ingrid A. Mayer, Vanderbilt University, Nashville, TN; Amye J. Tevaarwerk, University of Wisconsin, Madison, WI; Joseph A. Sparano, Montefiore Hospital and Medical Center, Bronx; Chau T. Dang, Memorial Sloan Kettering Cancer Center, New York, NY; Carolyn B. Hendricks, Association Community Clinical Oncology Program, Bethesda, MD; Donald W. Northfelt, Mayo Clinic, Scottsdale, AZ; and George W. Sledge JR, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1200/JCO.2018.79.2028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118403PMC
September 2018

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.

N Engl J Med 2018 Jul 3;379(2):111-121. Epub 2018 Jun 3.

From Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); Sunnybrook Research Institute, Toronto (K.I.P.), and McMaster University, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Chicago Stritch School of Medicine, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), and Duke University Medical Center, Durham (J.A.O.) - both in North Carolina; Mayo Clinic, Jacksonville, FL (M.P.G.); National Institutes of Health, National Cancer Institute, Bethesda, MD (T.L., J.A.); Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.), Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Washington University, St. Louis (M.J.E.); National Surgical Adjuvant Breast and Bowel Project Pathology Office (S.P.) and University of Pittsburgh (A.M.B.), Pittsburgh; Emory University, Atlanta (W.C.W.); University of Texas, San Antonio (P.M.R.); Cancer Trials Ireland, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); and University of Hawaii Cancer Center, Honolulu (J.L.B.).

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http://www.nejm.org/doi/10.1056/NEJMoa1804710
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http://dx.doi.org/10.1056/NEJMoa1804710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172658PMC
July 2018

Local Control of Distant Disease: Yes, but Where to Next?

Authors:
George W Sledge

J Oncol Pract 2018 06;14(6):357-358

Stanford University School of Medicine, Palo Alto, CA.

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http://dx.doi.org/10.1200/JOP.18.00247DOI Listing
June 2018

Molecular Characterization and Mortality From Breast Cancer in Men.

J Clin Oncol 2018 05 27;36(14):1396-1404. Epub 2018 Mar 27.

Suleiman Alfred Massarweh and George W. Sledge, Stanford University School of Medicine and Stanford Cancer Institute, Stanford; Dave P. Miller, Debbie McCullough, and Steven Shak, Genomic Health, Redwood City, CA; and Valentina I. Petkov, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2017.76.8861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075854PMC
May 2018

Altered expression of telomere-associated genes in leukocytes among BRCA1 and BRCA2 carriers.

Mol Carcinog 2018 04 5;57(4):567-575. Epub 2018 Jan 5.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1002/mc.22773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832588PMC
April 2018

MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2- Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy.

J Clin Oncol 2017 Sep 3;35(25):2875-2884. Epub 2017 Jun 3.

George W. Sledge Jr., Stanford University, Stanford; Han Koh, Kaiser Permanente Medical Group, Bellflower, CA; Masakazu Toi, Kyoto University; Kenichi Inoue, Saitama Cancer Center, Saitama; Norikazu Masuda, Osaka National Hospital, Osaka, Japan; Patrick Neven, Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg, Leuven, Belgium; Joohyuk Sohn, Yonsei Cancer Center, Seoul, Korea; Xavier Pivot, CHU de Besancon Hopital Jean Minjoz, Besancon Cedex; Nawel Bourayou, Eli Lilly, Paris, France; Olga Burdaeva, Arkhangelsk Regional Clinical Oncology Dispensary, Arkhangelsk, Russian Federation; Meena Okera, Adelaide Cancer Centre, Adelaide, Australia; Peter A. Kaufman, Dartmouth-Hitchcock Medical Center, Lebanon, NH; Eva-Maria Grischke, Universitätsklinikum Tübingen Frauenklinik, Tübingen, Germany; Martin Frenzel, Yong Lin, and Ian C. Smith, Eli Lilly, Indianapolis, IN; Susana Barriga, Eli Lilly, Madrid; and Antonio Llombart-Cussac, Hospital Arnau Vilanova, Valencia, Spain.

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http://ascopubs.org/doi/10.1200/JCO.2017.73.7585
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http://dx.doi.org/10.1200/JCO.2017.73.7585DOI Listing
September 2017

Reply to L.B. Marks et al.

J Clin Oncol 2017 04 9;35(11):1258-1259. Epub 2017 Jan 9.

Abram Recht, Beth Israel Deaconess Medical Center, Boston, MA; Elizabeth A. Comen, Memorial Sloan Kettering Cancer Center, New York, NY; Richard E. Fine, The West Clinic Comprehensive Breast Center, Germantown, TN; Gini F. Fleming, University of Chicago Medical Center, Chicago, IL; Patricia H. Hardenbergh, Shaw Regional Cancer Center, Edwards, CO; Alice Y. Ho, Memorial Sloan Kettering Cancer Center, New York, NY; Clifford A. Hudis, American Society of Clinical Oncology, Alexandria, VA; E. Shelley Hwang, Duke University Medical Center, Durham, NC; Jeffrey J. Kirshner, Hematology-Oncology Associates of Central New York, East Syracuse, NY; Monica Morrow, Memorial Sloan Kettering Cancer Center, New York, NY; Kilian E. Salerno, Roswell Park Cancer Institute, Buffalo, NY; George W. Sledge Jr, Stanford University Medical Center, Palo Alto, CA; Lawrence J. Solin, Albert Einstein Healthcare Network, Philadelphia, PA; Patricia A. Spears, North Carolina State University, Raleigh, NC; Timothy J. Whelan, McMaster University, Hamilton, Ontario, Canada; Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; and Stephen B. Edge, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.3966DOI Listing
April 2017

Put Some PEPI in Your Step: Ki67's Long Road to Respectability.

Authors:
George W Sledge

J Clin Oncol 2017 04 21;35(10):1031-1032. Epub 2017 Feb 21.

George W. Sledge Jr, Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1200/JCO.2016.71.2182DOI Listing
April 2017

Collective Wisdom: Lobular Carcinoma of the Breast.

Am Soc Clin Oncol Educ Book 2016 ;35:18-21

From the Division of Oncology, Stanford University School of Medicine, Stanford, CA; Yale University, New Haven, CT; The University of North Carolina at Chapel Hill, Chapel Hill, NC.

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http://dx.doi.org/10.1200/EDBK_100002DOI Listing
January 2017

Postmastectomy Radiotherapy: An American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Focused Guideline Update.

J Clin Oncol 2016 12 30;34(36):4431-4442. Epub 2016 Sep 30.

Abram Recht, Beth Israel Deaconess Medical Center, Boston, MA; Elizabeth A. Comen, Alice Y. Ho, Clifford A. Hudis, Monica Morrow, Memorial Sloan Kettering Cancer Center; New York; Jeffrey J. Kirshner, Hematology Oncology Associates of Central New York, East Syracuse; Kilian E. Salerno and Stephen B. Edge, Roswell Park Cancer Institute, Buffalo, NY; Richard E. Fine, West Clinic Comprehensive Breast Center, Germantown, TN; Gini F. Fleming, University of Chicago Medical Center, Chicago, IL; Patricia H. Hardenbergh, Shaw Regional Cancer Center, Edwards, CO; E. Shelley Hwang, Duke University Medical Center, Durham; Patricia A. Spears, North Carolina State University, Raleigh, NC; George W. Sledge Jr, Stanford University Medical Center, Palo Alto, CA; Lawrence J. Solin, Albert Einstein Healthcare Network, Philadelphia, PA; Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; and Timothy J. Whelan, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2016.69.1188DOI Listing
December 2016

Small-molecule binding sites to explore protein-protein interactions in the cancer proteome.

Mol Biosyst 2016 10 25;12(10):3067-87. Epub 2016 Jul 25.

Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1039/c6mb00231eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030169PMC
October 2016

Aberrant nocturnal cortisol and disease progression in women with breast cancer.

Breast Cancer Res Treat 2016 07 17;158(1):43-50. Epub 2016 Jun 17.

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/s10549-016-3864-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938753PMC
July 2016

Use of Gene Expression Profiling and Chemotherapy in Early-Stage Breast Cancer: A Study of Linked Electronic Medical Records, Cancer Registry Data, and Genomic Data Across Two Health Care Systems.

J Oncol Pract 2016 06 24;12(6):e697-709. Epub 2016 May 24.

Stanford University School of Medicine, Stanford; Palo Alto Medical Foundation Research Institute, Palo Alto; San Diego State University, San Diego; Cancer Prevention Institute of California, Fremont; Genomic Health Inc, Redwood City, CA; and Geisel School of Medicine, Lebanon, NH

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http://dx.doi.org/10.1200/JOP.2015.009803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957259PMC
June 2016

Targeted Therapy for Cancer in the Genomic Era.

Cancer J 2015 Jul-Aug;21(4):294-8

From the Division of Medical Oncology, Stanford University School of Medicine, Stanford, CA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PPO.0000000000000135DOI Listing
May 2016

Adjuvant Therapy for Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Detour on the Road to a Cure.

Authors:
George W Sledge

J Clin Oncol 2016 Apr 23;34(10):1021-3. Epub 2015 Dec 23.

Stanford University School of Medicine, Stanford, CA

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http://dx.doi.org/10.1200/JCO.2015.64.7511DOI Listing
April 2016

Nodular Regenerative Hyperplasia After Treatment With Trastuzumab Emtansine.

J Clin Oncol 2016 Jan 28;34(3):e9-12. Epub 2014 Apr 28.

Indiana University School of Medicine, Indiana University Health, Indianapolis, IN

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http://dx.doi.org/10.1200/JCO.2013.49.8543DOI Listing
January 2016

Curing Metastatic Breast Cancer.

Authors:
George W Sledge

J Oncol Pract 2016 Jan;12(1):6-10

Stanford University School of Medicine, Stanford, CA

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http://dx.doi.org/10.1200/JOP.2015.008953DOI Listing
January 2016

CancerLinQ and the future of cancer care.

Am Soc Clin Oncol Educ Book 2013 :430-4

From Stanford University, Stanford, CA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; American Society of Clinical Oncology, Alexandria, VA.

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http://dx.doi.org/10.14694/EdBook_AM.2013.33.430DOI Listing
December 2015

Pilot trial of paclitaxel-trastuzumab adjuvant therapy for early stage breast cancer: a trial of the ECOG-ACRIN cancer research group (E2198).

Br J Cancer 2015 Dec 1;113(12):1651-7. Epub 2015 Dec 1.

Department of Medicine, University of Pittsburgh Cancer Institute and UMPC Cancer Center, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1038/bjc.2015.405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701997PMC
December 2015

Prospective Validation of a 21-Gene Expression Assay in Breast Cancer.

N Engl J Med 2015 Nov 27;373(21):2005-14. Epub 2015 Sep 27.

From the Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); Sunnybrook Research Institute, Toronto (K.I.P.) and Juravinski Cancer Center, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Medical Center, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), Duke University Medical Center, Durham (J.A.O.), Wake Forest University Health Service, Winston-Salem (L.I.W.), and Southeast Clinical Oncology Research Consortium, Goldsboro (J.N.A.) - all in North Carolina; Mayo Clinic, Jacksonville, FL (E.A.P.); University of Maryland School of Medicine, Baltimore (J.A.O.), and National Institutes of Health, Bethesda (J.Z., T.L.) - both in Maryland; Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.) - both in Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Baylor College of Medicine, Houston (M.J.E.), and University of Texas, San Antonio (P.R.) - both in Texas; Washington University, St. Louis (M.J.E.); Allegheny General Hospital (S.P.) and University of Pittsburgh (A.M.B.) - both in Pittsburgh; the Department of Medical Oncology and Breast Center, Yonsei University College of Medicine, Seoul, South Korea (S.P.); Emory University, Atlanta (W.C.W.); Irish Clinical Oncology Research Group, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); University of Hawaii Cancer Center, Honolulu (J.L.B.); and Stanford University, Stanford, CA (G.W.S.)

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http://dx.doi.org/10.1056/NEJMoa1510764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701034PMC
November 2015

Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer.

J Clin Oncol 2015 Jul 15;33(21):2353-60. Epub 2015 Jun 15.

Joseph A. Sparano, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY; Fengmin Zhao and Jennifer A. Ligibel, Dana-Farber Cancer Institute-Harvard University, Boston, MA; Silvana Martino, John Wayne Cancer Institute, Santa Monica, CA; Edith A. Perez, Mayo Clinic, Jacksonville, FL; Tom Saphner, Vince Lombardi Cancer Center, Two Rivers, WI; Antonio C. Wolff, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD; George W. Sledge Jr, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN; William C. Wood, Winship Cancer Center, Emory University, Atlanta, GA; and Nancy E. Davidson, University of Pittsburgh Cancer Institute and University of Pittsburgh Medical Center Cancer Center, Pittsburgh, PA.

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http://jco.ascopubs.org/content/33/21/2353.full.pdf
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http://jco.ascopubs.org/content/early/2015/06/15/JCO.2015.60
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.60.9271
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http://dx.doi.org/10.1200/JCO.2015.60.9271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500829PMC
July 2015

"Vertical" Inhibition of HER2 Yields Horizontal Gains in the Clinic.

Clin Cancer Res 2015 Jun;21(12):2663-5

Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-3183DOI Listing
June 2015

Everything old is neu again: cellular senescence in HER2-positive breast cancer.

J Natl Cancer Inst 2015 May 13;107(5). Epub 2015 May 13.

Stanford Cancer Institute, Stanford University, Stanford, CA (GWS, MDP).

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http://dx.doi.org/10.1093/jnci/djv091DOI Listing
May 2015

Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.

J Clin Oncol 2015 Mar 20;33(7):701-8. Epub 2015 Jan 20.

Edith A. Perez, E. Aubrey Thompson, Yan W. Asmann, and Xochiquetzal J. Geiger, Mayo Clinic, Jacksonville, FL; Karla V. Ballman, S. Keith Anderson, Krishna R. Kalari, Jeanette E. Eckel-Passow, Kathleen S. Tenner, Jin Jen, Beiyun Chen, Robert B. Jenkins, and Monica M. Reinholz, Mayo Clinic, Rochester, MN; Amylou C. Dueck, and Ann E. McCullough, Mayo Clinic, Scottsdale, AZ; Jian-Bing Fan, Illumina, San Diego, CA; George W. Sledge, Stanford School of Medicine, Palo Alto, CA; Eric P. Winer, Harvard Medical School, Boston, MA; and Julie R. Gralow, Seattle Cancer Care Alliance, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2014.57.6298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334774PMC
March 2015

The future of breast cancer systemic therapy: the next 10 years.

J Mol Med (Berl) 2015 Feb 9;93(2):119-25. Epub 2015 Jan 9.

Department of Medicine, Division of Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA, 94305-5826, USA.

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http://dx.doi.org/10.1007/s00109-014-1238-yDOI Listing
February 2015

Anti-vascular endothelial growth factor therapy in breast cancer: game over?

Authors:
George W Sledge

J Clin Oncol 2015 Jan 27;33(2):133-5. Epub 2014 Oct 27.

Stanford University School of Medicine, Palo Alto, CA

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http://dx.doi.org/10.1200/JCO.2014.58.1298DOI Listing
January 2015

Treatment-associated musculoskeletal and vasomotor symptoms and relapse-free survival in the NCIC CTG MA.27 adjuvant breast cancer aromatase inhibitor trial.

J Clin Oncol 2015 Jan 15;33(3):265-71. Epub 2014 Dec 15.

Vered Stearns, Kimmel Cancer Center, Johns Hopkins, Baltimore, MD; Judith-Anne W. Chapman, Aurélie Le Maitre, Jessica Kundapur, and Lois E. Shepherd, NCIC Clinical Trials Group, Queen's University, Kingston; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre and University of Toronto, Toronto, Ontario, Canada; Cynthia X. Ma, Siteman Cancer Center, Washington University, St Louis, MO; Matthew J. Ellis, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX; James N. Ingle, Mayo Clinic, Rochester, MN; G. Thomas Budd, Cleveland Clinic, Cleveland, OH; George W. Sledge, Stanford University, San Francisco, CA; Pedro E.R. Liedke and Paul E. Goss, Harvard University; Paul E. Goss, Avon International Breast Cancer Research Program, Massachusetts General Hospital, Boston, MA; Manuela Rabaglio, Inselspital University Hospital and International Breast Cancer Study Group Coordinating Center, Berne, Switzerland; and Pedro E.R. Liedke, Hospital de Clínicas de Porto Alegre and Instituto do Cancer Mãe de Deus, Oncologia, Porto Alegre, Rio Grande do Sul, Brazil.

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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.57.6926
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http://dx.doi.org/10.1200/JCO.2014.57.6926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289722PMC
January 2015

Decade in review-targeted therapy: successes, toxicities and challenges in solid tumours.

Nat Rev Clin Oncol 2014 Nov 7;11(11):627-8. Epub 2014 Oct 7.

Division of Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA 94305-5826, USA.

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http://dx.doi.org/10.1038/nrclinonc.2014.171DOI Listing
November 2014

Improving the quality of cancer care in America through health information technology.

J Am Med Inform Assoc 2014 Sep-Oct;21(5):772-5. Epub 2013 Dec 18.

Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, California, USA Schools of Medicine and Public Health, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/amiajnl-2013-002346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147622PMC
October 2014

Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines.

Clin Exp Metastasis 2014 Oct 3;31(7):771-86. Epub 2014 Aug 3.

Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Building 37/Room 1126, 37 Convent Drive, Bethesda, MD, 20892, USA,

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http://dx.doi.org/10.1007/s10585-014-9667-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948753PMC
October 2014

Heterogeneity and cancer.

Oncology (Williston Park) 2014 Sep;28(9):772-8

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September 2014

Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer.

J Cancer 2014 15;5(8):633-45. Epub 2014 Aug 15.

1. Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN; ; 3. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN;

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http://dx.doi.org/10.7150/jca.8466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142325PMC
August 2014

Examining and predicting drug preferences of patients with metastatic breast cancer: using conjoint analysis to examine attributes of paclitaxel and capecitabine.

Breast Cancer Res Treat 2014 May 20;145(1):83-9. Epub 2014 Mar 20.

Research Advocacy Network, 6505 W. Park Blvd., Suite 305, PMB 220, Plano, TX, 75093, USA,

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http://dx.doi.org/10.1007/s10549-014-2909-7DOI Listing
May 2014

TCGA's breast cancer project may yield important therapeutic benefits, but it's too early to be sure.

Oncology (Williston Park) 2013 Dec;27(12):1280, 1282

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December 2013

Impact of c-MYC protein expression on outcome of patients with early-stage HER2+ breast cancer treated with adjuvant trastuzumab NCCTG (alliance) N9831.

Clin Cancer Res 2013 Oct 21;19(20):5798-807. Epub 2013 Aug 21.

Authors' Affiliations: Section of Biostatistics; Division of Anatomic Pathology, Mayo Clinic, Scottsdale, Arizona; Division of Experimental Pathology, Department of Laboratory Medicine and Pathology; Division of Biomedical Statistics and Informatics and Medical Oncology, Mayo Clinic, Rochester, Minnesota; Division of Anatomic Pathology and Hematology/Oncology, Mayo Clinic, Jacksonville, Florida; Division of Hematology/Oncology, University of Pittsburgh Cancer Institute and UPMC Cancer Center, Pittsburgh, Pennsylvania; The Angeles Clinic and Research Institute, Santa Monica, California; Indiana University Medical Center Cancer Pavilion, Indianapolis, Indiana; Division of Hematology/Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; Oncology Associates of Cedar Rapids, Cedar Rapids, Iowa; Seattle Cancer Care Alliance, Seattle, Washington; and Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805021PMC
October 2013

Molecular analysis of thymoma.

PLoS One 2012 13;7(8):e42669. Epub 2012 Aug 13.

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042669PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418289PMC
April 2013

Synthesis of radiolabeled protein disulfide isomerase (PDI) inhibitors as new potential PET agents for imaging of the enzyme PDI in neurological disorders and cancer.

Appl Radiat Isot 2013 Apr 8;74:61-9. Epub 2013 Jan 8.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 1345 West 16th Street, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.apradiso.2013.01.003DOI Listing
April 2013

Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis.

Bioorg Med Chem 2013 Apr 9;21(7):2145-55. Epub 2013 Jan 9.

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Van Nuys Medical Science Building, MS 4023, 635 Barnhill Drive, Indianapolis, IN 46202-5122, USA.

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http://dx.doi.org/10.1016/j.bmc.2012.12.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625246PMC
April 2013

Investigational drug MLN0128, a novel TORC1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models.

Breast Cancer Res Treat 2012 Dec 21;136(3):673-82. Epub 2012 Oct 21.

Department of Medicine, Indiana University School of Medicine, Walther Hall, 980 W Walnut Street, Building R3, Room C230, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1007/s10549-012-2298-8DOI Listing
December 2012

Establishment and characterization of a novel cell line derived from human thymoma AB tumor.

Lab Invest 2012 Nov 27;92(11):1564-73. Epub 2012 Aug 27.

Department of Medicine, Indiana University School of Medicine, Walther Hall, 980W Walnut Street, C230, IN 46202, USA.

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http://dx.doi.org/10.1038/labinvest.2012.115DOI Listing
November 2012

ASCO 2012: a good year for HER2 therapy.

Authors:
George W Sledge

Clin Breast Cancer 2012 Aug;12(4):231

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http://dx.doi.org/10.1016/j.clbc.2012.06.001DOI Listing
August 2012

Synthesis of 2-[11C]methoxy-3,17β-O,O-bis(sulfamoyl)estradiol as a new potential PET agent for imaging of steroid sulfatase (STS) in cancers.

Steroids 2012 Jul 19;77(8-9):864-70. Epub 2012 Apr 19.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.steroids.2012.04.007DOI Listing
July 2012

TOP2A RNA expression and recurrence in estrogen receptor-positive breast cancer.

Breast Cancer Res Treat 2012 Jul 16;134(2):751-7. Epub 2012 Jun 16.

Weiler Division, Montefiore-Einstein Cancer Center, Albert Einstein College of Medicine, Montefiore Medical Center, 1825 Eastchester Rd., Bronx, NY 10461, USA.

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http://link.springer.com/10.1007/s10549-012-2112-7
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http://dx.doi.org/10.1007/s10549-012-2112-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965271PMC
July 2012

[11C]GSK2126458 and [18F]GSK2126458, the first radiosynthesis of new potential PET agents for imaging of PI3K and mTOR in cancers.

Bioorg Med Chem Lett 2012 Feb 10;22(4):1569-74. Epub 2012 Jan 10.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.bmcl.2011.12.136DOI Listing
February 2012

Making personalized cancer medicine a reality: challenges and opportunities in the development of biomarkers and companion diagnostics.

Clin Cancer Res 2012 Feb;18(3):619-24

Nodality, Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2017DOI Listing
February 2012