George Smith

George Smith

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George Smith

George Smith

Publications by authors named "George Smith"

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A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication.

Authors:
Sean Pymer Joanne Palmer Amy E Harwood Lee Ingle George E Smith Ian C Chetter

J Vasc Surg 2019 Dec 27;70(6):2076-2087. Epub 2019 Jun 27.

Academic Vascular Surgical Unit, Vascular Department, Hull Royal Infirmary, Hull, United Kingdom.

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http://dx.doi.org/10.1016/j.jvs.2019.03.050DOI Listing
December 2019

A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data.

Authors:
Ryan J Langdon Rebecca C Richmond Gibran Hemani Jie Zheng Kaitlin H Wade Robert Carreras-Torres Mattias Johansson Paul Brennan Robyn E Wootton Marcus R Munafo George Davey Smith Caroline L Relton Emma E Vincent Richard M Martin Philip Haycock

Cancer Epidemiol Biomarkers Prev 2019 Dec 17;28(12):2070-2078. Epub 2019 Jul 17.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-19-0036DOI Listing
December 2019

AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury.

Authors:
Brittany A Charsar Michael A Brinton Katherine Locke Anna Y Chen Biswarup Ghosh Mark W Urban Sreeya Komaravolu Karthik Krishnamurthy Rupert Smit Piera Pasinelli Megan C Wright George M Smith Angelo C Lepore

FASEB J 2019 Dec 2;33(12):13775-13793. Epub 2019 Oct 2.

Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College, Jefferson College of Life Sciences, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1096/fj.201901730RDOI Listing
December 2019

DNA methylation and miRNA-1296 act in concert to mediate spatiotemporal expression of KPNA7 during bovine oocyte and early embryonic development.

Authors:
Lei Wang Jacqelyn M Hand Liyuan Fu George W Smith Jianbo Yao

BMC Dev Biol 2019 Dec 2;19(1):23. Epub 2019 Dec 2.

Laboratory of Animal Biotechnology and Genomics, Division of Animal and Nutritional Sciences, West Virginia University, Morgantown, WV, 26506, USA.

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http://dx.doi.org/10.1186/s12861-019-0204-xDOI Listing
December 2019

Neurotrophins induce fission of mitochondria along embryonic sensory axons.

Authors:
Lorena Armijo-Weingart Andrea Ketschek Rajiv Sainath Almudena Pacheco George M Smith Gianluca Gallo

Elife 2019 Dec 2;8. Epub 2019 Dec 2.

Department of Anatomy and Cell Biology, Shriner Hospitals Pediatric Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, United States.

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http://dx.doi.org/10.7554/eLife.49494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887118PMC
December 2019

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.

Authors:
Jorien L Treur Ditte Demontis George Davey Smith Hannah Sallis Tom G Richardson Reinout W Wiers Anders D Børglum Karin J H Verweij Marcus R Munafò

Addict Biol 2019 Nov 16:e12849. Epub 2019 Nov 16.

School of Psychological Science, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1111/adb.12849DOI Listing
November 2019

A prospective observational cohort study of concomitant versus sequential phlebectomy for tributary varicosities following axial mechanochemical ablation.

Authors:
Abduraheem Mohamed Clement Leung Louise Hitchman Tom Wallace George Smith Daniel Carradice Ian Chetter

Phlebology 2019 Oct 13;34(9):627-635. Epub 2019 Mar 13.

Academic Vascular Surgical Unit, Hull York Medical School, Hull, UK.

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http://journals.sagepub.com/doi/10.1177/0268355519835625
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http://dx.doi.org/10.1177/0268355519835625DOI Listing
October 2019

Phage Display: Simple Evolution in a Petri Dish (Nobel Lecture).

Authors:
George P Smith

Angew Chem Int Ed Engl 2019 Oct 17;58(41):14428-14437. Epub 2019 Sep 17.

University of Missouri, Division of Biological Sciences, Tucker Hall, Columbia, MO, 65211-7400, USA.

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http://dx.doi.org/10.1002/anie.201908308DOI Listing
October 2019

The Parkinson's Disease Mendelian Randomization Research Portal.

Authors:
Alastair J Noyce Sara Bandres-Ciga Jonggeol Kim Karl Heilbron Demis Kia Gibran Hemani Angli Xue Debbie A Lawlor George Davey Smith Raquel Duran Ziv Gan-Or Cornelis Blauwendraat J Raphael Gibbs David A Hinds Jian Yang Peter Visscher Jack Cuzick Huw Morris John Hardy Nicholas W Wood Mike A Nalls Andrew B Singleton

Mov Disord 2019 Oct 28. Epub 2019 Oct 28.

Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/mds.27873DOI Listing
October 2019

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 Oct 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/s41467-019-12283-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Protein Tyrosine Phosphatase σ Inhibitory Peptide Promotes Recovery of Diaphragm Function and Sprouting of Bulbospinal Respiratory Axons after Cervical Spinal Cord Injury.

Authors:
Mark W Urban Biswarup Ghosh Cole G Block Brittany A Charsar George M Smith Megan C Wright Shuxin Li Angelo C Lepore

J Neurotrauma 2019 Sep 18. Epub 2019 Sep 18.

Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

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https://www.liebertpub.com/doi/10.1089/neu.2019.6586
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http://dx.doi.org/10.1089/neu.2019.6586DOI Listing
September 2019

Partial Reconstruction of the Nigrostriatal Circuit along a Preformed Molecular Guidance Pathway.

Authors:
Biswarup Ghosh Chen Zhang Kristine S Ziemba Anita M Fletcher David M Yurek George M Smith

Mol Ther Methods Clin Dev 2019 Sep 11;14:217-227. Epub 2019 Jul 11.

Center for Neural Repair and Rehabilitation, Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.omtm.2019.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690717PMC
September 2019

Long-Distance Axon Regeneration Promotes Recovery of Diaphragmatic Respiratory Function after Spinal Cord Injury.

Authors:
Mark W Urban Biswarup Ghosh Cole G Block Laura R Strojny Brittany A Charsar Miguel Goulão Sreeya S Komaravolu George M Smith Megan C Wright Shuxin Li Angelo C Lepore

eNeuro 2019 Sep/Oct;6(5). Epub 2019 Sep 26.

Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107

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http://dx.doi.org/10.1523/ENEURO.0096-19.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794082PMC
September 2019

Emerging molecular therapeutic targets for spinal cord injury.

Authors:
Shuo Wang George M Smith Michael E Selzer Shuxin Li

Expert Opin Ther Targets 2019 Sep 4;23(9):787-803. Epub 2019 Sep 4.

Shriners Hospitals Pediatric Research Center, Temple University School of Medicine , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/14728222.2019.1661381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787917PMC
September 2019

Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease.

Authors:
Brian A Ference Deepak L Bhatt Alberico L Catapano Chris J Packard Ian Graham Stephen Kaptoge Thatcher B Ference Qi Guo Ulrich Laufs Christian T Ruff Arjen Cupido G Kees Hovingh John Danesh Michael V Holmes George Davey Smith Kausik K Ray Stephen J Nicholls Marc S Sabatine

JAMA 2019 Sep 2. Epub 2019 Sep 2.

Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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https://jamanetwork.com/journals/jama/fullarticle/2749533
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http://dx.doi.org/10.1001/jama.2019.14120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724415PMC
September 2019

Introducing M-GCTA a Software Package to Estimate Maternal (or Paternal) Genetic Effects on Offspring Phenotypes.

Authors:
Zhen Qiao Jie Zheng Øyvind Helgeland Marc Vaudel Stefan Johansson Pål R Njølstad George Davey Smith Nicole M Warrington David M Evans

Behav Genet 2019 Sep 6. Epub 2019 Sep 6.

University of Queensland Diamantina Institute, University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1007/s10519-019-09969-4DOI Listing
September 2019

Mechanochemical ablation for the treatment of superficial venous incompetence: A cohort study of a single centre's early experience.

Authors:
Abduraheem H Mohamed Clement Leung Tom Wallace Sean Pymer Amy Harwood George Smith Daniel Carradice Ian C Chetter

Phlebology 2019 Aug 30;34(7):466-473. Epub 2018 Dec 30.

Hull York Medical School, Academic Vascular Surgical Unit, Alderson House, Hull Royal Infirmary, Hull, UK.

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http://dx.doi.org/10.1177/0268355518818339DOI Listing
August 2019

A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection.

Authors:
Joshua P Totty Louise H Hitchman Paris L Cai Amy E Harwood Tom Wallace Dan Carradice George E Smith Ian C Chetter

Int Wound J 2019 Aug 14;16(4):883-890. Epub 2019 Mar 14.

Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, UK.

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http://dx.doi.org/10.1111/iwj.13113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850133PMC
August 2019

Availability of public databases for triangulation of findings.

Authors:
Matthew Lyon Marcus Munafo Tom Gaunt George Davey Smith

Proc Natl Acad Sci U S A 2019 Aug 23;116(32):15766-15767. Epub 2019 Jul 23.

National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University of Bristol, Oakfield House, Bristol BS8 2BN, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1908893116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689894PMC
August 2019

Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.

Authors:
Pirro G Hysi Ana M Valdes Fan Liu Nicholas A Furlotte David M Evans Veronique Bataille Alessia Visconti Gibran Hemani George McMahon Susan M Ring George Davey Smith David L Duffy Gu Zhu Scott D Gordon Sarah E Medland Bochao D Lin Gonneke Willemsen Jouke Jan Hottenga Dragana Vuckovic Giorgia Girotto Ilaria Gandin Cinzia Sala Maria Pina Concas Marco Brumat Paolo Gasparini Daniela Toniolo Massimiliano Cocca Antonietta Robino Seyhan Yazar Alex W Hewitt Yan Chen Changqing Zeng Andre G Uitterlinden M Arfan Ikram Merel A Hamer Cornelia M van Duijn Tamar Nijsten David A Mackey Mario Falchi Dorret I Boomsma Nicholas G Martin David A Hinds Manfred Kayser Timothy D Spector

Nat Genet 2019 Jul;51(7):1190

King's College London Department of Twins Research and Genetic Epidemiology, London, UK.

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http://dx.doi.org/10.1038/s41588-019-0446-3DOI Listing
July 2019

Surveillance arterioveNous fistulAs using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for a multicentre observational study.

Authors:
James Richards Mohammed Hossain Dominic Summers Matthew Slater Matthew Bartlett Vasilis Kosmoliaptsis Edward Cf Wilson Regin Lagaac Anna Sidders Claire Foley Emma Laing Valerie Hopkins Chloe Fitzpatrick-Creamer Cara Hudson Helen Thomas Sam Turner Andrew Tambyraja Subash Somalanka James Hunter Sam Dutta Sarah Lawman Tracey Salter Mohammed Aslam Atul Bagul Rajesh Sivaprakasam George Smith Zia Moinuddin Simon Knight Paul Gibbs Reza Motallebzadeh Nicholas Barnett Gavin Pettigrew

BMJ Open 2019 Jul 23;9(7):e031210. Epub 2019 Jul 23.

Department of Surgery, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1136/bmjopen-2019-031210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661628PMC
July 2019

Altered Amniotic Fluid Levels of Hyaluronic Acid in Fetal Rats with Myelomeningocele: Understanding Spinal Cord Injury.

Authors:
Jolanta Zieba Maciej Walczak Oleg Gordiienko Jonathan A Gerstenhaber George M Smith Barbara Krynska

J Neurotrauma 2019 Jun 19;36(12):1965-1973. Epub 2018 Dec 19.

1 Shriners Hospitals Pediatric Research Center, Center for Neural Repair and Rehabilitation, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.

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https://www.liebertpub.com/doi/10.1089/neu.2018.5894
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http://dx.doi.org/10.1089/neu.2018.5894DOI Listing
June 2019

Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication.

Authors:
Amy E Harwood Joshua P Totty Sean Pymer Chao Huang Louise Hitchman Daniel Carradice Tom Wallace George Edward Smith Ian C Chetter

J Vasc Surg 2019 06 21;69(6):1899-1908.e1. Epub 2018 Dec 21.

Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S07415214183248
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http://dx.doi.org/10.1016/j.jvs.2018.10.065DOI Listing
June 2019

Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study.

Authors:
Rebecca C Richmond Emma L Anderson Hassan S Dashti Samuel E Jones Jacqueline M Lane Linn Beate Strand Ben Brumpton Martin K Rutter Andrew R Wood Kurt Straif Caroline L Relton Marcus Munafò Timothy M Frayling Richard M Martin Richa Saxena Michael N Weedon Debbie A Lawlor George Davey Smith

BMJ 2019 Jun 26;365:l2327. Epub 2019 Jun 26.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmj.l2327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592406PMC
June 2019

Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial.

Authors:
Rhona A Beynon Rebecca C Richmond Diana L Santos Ferreira Andrew R Ness Margaret May George Davey Smith Emma E Vincent Charleen Adams Mika Ala-Korpela Peter Würtz Sebastian Soidinsalo Christopher Metcalfe Jenny L Donovan Athene J Lane Richard M Martin

Int J Cancer 2019 04 7;144(8):1918-1928. Epub 2018 Dec 7.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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http://doi.wiley.com/10.1002/ijc.31929
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http://dx.doi.org/10.1002/ijc.31929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491994PMC
April 2019

The Intrarater and Interrater Reliability of Measures Derived from Cardiopulmonary Exercise Testing in Patients with Abdominal Aortic Aneurysms.

Authors:
Amy Elizabeth Harwood Sean Pymer Louise Hitchman Joshua Totty Tom Wallace George E Smith Daniel Carradice Sean Carroll Ian C Chetter

Ann Vasc Surg 2019 Apr 23;56:175-182. Epub 2018 Nov 23.

Academic Vascular Surgical Unit, Hull York Medical School, Hull Royal Infirmary, Anlaby Road, Hull HU3 2JZ, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S08905096183085
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http://dx.doi.org/10.1016/j.avsg.2018.08.087DOI Listing
April 2019

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.

Authors:
Louise Helen Hitchman Joshua P Totty Ali Raza Paris Cai George E Smith Daniel Carradice Tom Wallace Amy E Harwood Ian C Chetter

Ann Vasc Surg 2019 Apr 26;56:330-339. Epub 2018 Nov 26.

Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S08905096183087
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http://dx.doi.org/10.1016/j.avsg.2018.10.013DOI Listing
April 2019

Transgenerational Effects of Periconception Heavy Metal Administration on Adipose Weight and Glucose Homeostasis in Mice at Maturity.

Authors:
Cagri Camsari Joseph K Folger Sandeep K Rajput Devin McGee Keith E Latham George W Smith

Toxicol Sci 2019 04;168(2):610-619

Laboratory of Mammalian Reproductive Biology and Genomics.

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http://dx.doi.org/10.1093/toxsci/kfz008DOI Listing
April 2019

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course.

Authors:
Herman T den Dekker Kimberley Burrows Janine F Felix Lucas A Salas Ivana Nedeljkovic Jin Yao Sheryl L Rifas-Shiman Carlos Ruiz-Arenas N Amin Mariona Bustamante Dawn L DeMeo A John Henderson Caitlin G Howe Marie-France Hivert M Arfan Ikram Johan C de Jongste Lies Lahousse Pooja R Mandaviya Joyce B van Meurs Mariona Pinart Gemma C Sharp Lisette Stolk André G Uitterlinden Josep M Anto Augusto A Litonjua Carrie V Breton Guy G Brusselle Jordi Sunyer George Davey Smith Caroline L Relton Vincent W V Jaddoe Liesbeth Duijts

Eur Respir J 2019 Apr 4;53(4). Epub 2019 Apr 4.

Dept of Pediatrics, Division of Respiratory Medicine and Allergology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

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http://dx.doi.org/10.1183/13993003.01795-2018DOI Listing
April 2019

A deer miss.

Authors:
Ross Coomber James Aldwinckle George Smith

Trauma Case Rep 2019 Apr 8;20:100176. Epub 2019 Feb 8.

Norfolk and Norwich University Hospital, United Kingdom.

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http://dx.doi.org/10.1016/j.tcr.2019.100176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370566PMC
April 2019

Effect of age at puberty on risk of multiple sclerosis: A mendelian randomization study.

Authors:
Adil Harroud John A Morris Vincenzo Forgetta Ruth Mitchell George Davey Smith Stephen J Sawcer J Brent Richards

Neurology 2019 04 20;92(16):e1803-e1810. Epub 2019 Mar 20.

From the Department of Neurology and Neurosurgery (A.H.), Department of Human Genetics (J.A.M., V.F., J.B.R.), Department of Medicine (J.B.R.), and Department of Epidemiology, Biostatistics and Occupational Health (J.B.R.), McGill University; Centre for Clinical Epidemiology (A.H., J.A.M., V.F., J.B.R.), Department of Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada; MRC Integrative Epidemiology Unit (R.M., G.D.S.), School of Social and Community Medicine, and Population Health Sciences (R.M., G.D.S., S.J.S.), Bristol Medical School, University of Bristol; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge; and Department of Twin Research and Genetic Epidemiology (J.B.R.), King's College London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550505PMC
April 2019

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.

Authors:
Amit V Khera Mark Chaffin Kaitlin H Wade Sohail Zahid Joseph Brancale Rui Xia Marina Distefano Ozlem Senol-Cosar Mary E Haas Alexander Bick Krishna G Aragam Eric S Lander George Davey Smith Heather Mason-Suares Myriam Fornage Matthew Lebo Nicholas J Timpson Lee M Kaplan Sekar Kathiresan

Cell 2019 Apr;177(3):587-596.e9

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661115PMC
April 2019

Retrogradely Transportable Lentivirus Tracers for Mapping Spinal Cord Locomotor Circuits.

Authors:
Imran S Sheikh Kathleen M Keefe Noelle A Sterling Ian P Junker Chidubem I Eneanya Yingpeng Liu Xiao-Qing Tang George M Smith

Front Neural Circuits 2018 25;12:60. Epub 2018 Jul 25.

Department of Neuroscience, Shriners Hospitals Pediatric Research Center, Center for Neural Rehabilitation and Repair, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fncir.2018.00060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068242PMC
March 2019

Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury.

Authors:
Miguel Goulão Biswarup Ghosh Mark W Urban Malya Sahu Christina Mercogliano Brittany A Charsar Sreeya Komaravolu Cole G Block George M Smith Megan C Wright Angelo C Lepore

Glia 2019 03 11;67(3):452-466. Epub 2018 Dec 11.

Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355351PMC
March 2019

Psychosocial Adversity in Infancy and Mortality Rates in Childhood and Adolescence: A Birth Cohort Study of 1.5 Million Individuals.

Authors:
Søren Dinesen Østergaard Janne Tidselbak Larsen Liselotte Petersen George Davey Smith Esben Agerbo

Epidemiology 2019 03;30(2):246-255

iPSYCH-The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

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March 2019

Direct Injection of a Lentiviral Vector Highlights Multiple Motor Pathways in the Rat Spinal Cord.

Authors:
Kathleen M Keefe Ian P Junker Imran S Sheikh Thomas J Campion George M Smith

J Vis Exp 2019 03 15(145). Epub 2019 Mar 15.

Shriner's Pediatric Research Center, Temple University;

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March 2019

Shielding materials in the compact spherical tokamak.

Authors:
Samuel A Humphry-Baker George D W Smith

Philos Trans A Math Phys Eng Sci 2019 Mar;377(2141):20170443

2 Tokamak Energy , 173 Brook Drive, Milton Park, Oxfordshire OX14 4SA , UK.

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http://dx.doi.org/10.1098/rsta.2017.0443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365859PMC
March 2019

Schizophrenia risk and reproductive success: a Mendelian randomization study.

Authors:
Rebecca B Lawn Hannah M Sallis Amy E Taylor Robyn E Wootton George Davey Smith Neil M Davies Gibran Hemani Abigail Fraser Ian S Penton-Voak Marcus R Munafò

R Soc Open Sci 2019 Mar 6;6(3):181049. Epub 2019 Mar 6.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1098/rsos.181049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458425PMC
March 2019

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate.

Authors:
Laurence J Howe Tom G Richardson Ryan Arathimos Lucas Alvizi Maria R Passos-Bueno Philip Stanier Ellen Nohr Kerstin U Ludwig Elisabeth Mangold Michael Knapp Evie Stergiakouli Beate St Pourcain George Davey Smith Jonathan Sandy Caroline L Relton Sarah J Lewis Gibran Hemani Gemma C Sharp

Epigenomics 2019 Feb 14;11(2):133-145. Epub 2019 Jan 14.

MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.2217/epi-2018-0091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462847PMC
February 2019

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

Authors:
Ioanna Tachmazidou Konstantinos Hatzikotoulas Lorraine Southam Jorge Esparza-Gordillo Valeriia Haberland Jie Zheng Toby Johnson Mine Koprulu Eleni Zengini Julia Steinberg Jeremy M Wilkinson Sahir Bhatnagar Joshua D Hoffman Natalie Buchan Dániel Süveges Laura Yerges-Armstrong George Davey Smith Tom R Gaunt Robert A Scott Linda C McCarthy Eleftheria Zeggini

Nat Genet 2019 02 21;51(2):230-236. Epub 2019 Jan 21.

Human Genetics, Wellcome Genome Campus, Wellcome Sanger Institute, Cambridge, UK.

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http://dx.doi.org/10.1038/s41588-018-0327-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400267PMC
February 2019

Coronary artery disease, genetic risk and the metabolome in young individuals.

Authors:
Thomas Battram Luke Hoskins David A Hughes Johannes Kettunen Susan M Ring George Davey Smith Nicholas J Timpson

Wellcome Open Res 2018 1;3:114. Epub 2019 Feb 1.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348437PMC
February 2019

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.

Authors:
Charleen D Adams Rebecca Richmond Diana L Santos Ferreira Wes Spiller Vanessa Tan Jie Zheng Peter Würtz Jenny Donovan Freddie Hamdy David Neal J Athene Lane George Davey Smith Caroline Relton Rosalind A Eeles Christopher A Haiman ZSofia Kote-Jarai Fredrick R Schumacher Ali Amin Al Olama Sara Benlloch Kenneth Muir Sonja I Berndt David V Conti Fredrik Wiklund Stephen J Chanock Susan Gapstur Victoria L Stevens Catherine M Tangen Jyotsna Batra Judith A Clements Henrik Gronberg Nora Pashayan Johanna Schleutker Demetrius Albanes Alicja Wolk Catharine M L West Lorelei A Mucci Géraldine Cancel-Tassin Stella Koutros Karina Dalsgaard Sorensen Lovise Maehle Ruth C Travis Robert J Hamilton Sue Ann Ingles Barry S Rosenstein Yong-Jie Lu Graham G Giles Adam S Kibel Ana Vega Manolis Kogevinas Kathryn L Penney Jong Y Park Janet L Stanford Cezary Cybulski Børge G Nordestgaard Hermann Brenner Christiane Maier Jeri Kim Esther M John Manuel R Teixeira Susan L Neuhausen Kim De Ruyck Azad Razack Lisa F Newcomb Davor Lessel Radka P Kaneva Nawaid Usmani Frank Claessens Paul A Townsend Manuela Gago Dominguez Monique J Roobol Florence Menegaux Kay-Tee Khaw Lisa A Cannon-Albright Hardev Pandha Stephen N Thibodeau Richard M Martin

Cancer Epidemiol Biomarkers Prev 2019 01 23;28(1):208-216. Epub 2018 Oct 23.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746173PMC
January 2019

Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1.

Authors:
Yosuke Ohtake Armin Sami Xinpei Jiang Makoto Horiuchi Kieran Slattery Lena Ma George M Smith Michael E Selzer Shin-Ichi Muramatsu Shuxin Li

Mol Ther 2019 01 1;27(1):102-117. Epub 2018 Nov 1.

Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA; Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319317PMC
January 2019

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Authors:
Andrew P Morris Thu H Le Haojia Wu Artur Akbarov Peter J van der Most Gibran Hemani George Davey Smith Anubha Mahajan Kyle J Gaulton Girish N Nadkarni Adan Valladares-Salgado Niels Wacher-Rodarte Josyf C Mychaleckyj Nicole D Dueker Xiuqing Guo Yang Hai Jeffrey Haessler Yoichiro Kamatani Adrienne M Stilp Gu Zhu James P Cook Johan Ärnlöv Susan H Blanton Martin H de Borst Erwin P Bottinger Thomas A Buchanan Sylvia Cechova Fadi J Charchar Pei-Lun Chu Jeffrey Damman James Eales Ali G Gharavi Vilmantas Giedraitis Andrew C Heath Eli Ipp Krzysztof Kiryluk Holly J Kramer Michiaki Kubo Anders Larsson Cecilia M Lindgren Yingchang Lu Pamela A F Madden Grant W Montgomery George J Papanicolaou Leslie J Raffel Ralph L Sacco Elena Sanchez Holger Stark Johan Sundstrom Kent D Taylor Anny H Xiang Aleksandra Zivkovic Lars Lind Erik Ingelsson Nicholas G Martin John B Whitfield Jianwen Cai Cathy C Laurie Yukinori Okada Koichi Matsuda Charles Kooperberg Yii-Der Ida Chen Tatjana Rundek Stephen S Rich Ruth J F Loos Esteban J Parra Miguel Cruz Jerome I Rotter Harold Snieder Maciej Tomaszewski Benjamin D Humphreys Nora Franceschini

Nat Commun 2019 01 3;10(1):29. Epub 2019 Jan 3.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC, 27516-8050, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318312PMC
January 2019

Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

Authors:
David L Duffy Gu Zhu Xin Li Marianna Sanna Mark M Iles Leonie C Jacobs David M Evans Seyhan Yazar Jonathan Beesley Matthew H Law Peter Kraft Alessia Visconti John C Taylor Fan Liu Margaret J Wright Anjali K Henders Lisa Bowdler Dan Glass M Arfan Ikram André G Uitterlinden Pamela A Madden Andrew C Heath Elliot C Nelson Adele C Green Stephen Chanock Jennifer H Barrett Matthew A Brown Nicholas K Hayward Stuart MacGregor Richard A Sturm Alex W Hewitt Manfred Kayser David J Hunter Julia A Newton Bishop Timothy D Spector Grant W Montgomery David A Mackey George Davey Smith Tamar E Nijsten D Timothy Bishop Veronique Bataille Mario Falchi Jiali Han Nicholas G Martin

Nat Commun 2019 01 14;10(1):299. Epub 2019 Jan 14.

QIMR Berghofer Medical Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.1038/s41467-018-08078-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331636PMC
January 2019

Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition.

Authors:
Ben M Brumpton Lars G Fritsche Jie Zheng Jonas Bille Nielsen Maria Mannila Ida Surakka Humaira Rasheed Gunnhild Åberge Vie Sarah E Graham Maiken Elvestad Gabrielsen Lars Erik Laugsand Pål Aukrust Lars Johan Vatten Jan Kristian Damås Thor Ueland Imre Janszky John-Anker Zwart Ferdinand M Van't Hooft Nabil Georges Seidah Kristian Hveem Cristen Willer George Davey Smith Bjørn Olav Åsvold

Circ Genom Precis Med 2019 01;12(1):e002335

Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530796PMC
January 2019

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis.

Authors:
Simon Haworth Ruth Mitchell Laura Corbin Kaitlin H Wade Tom Dudding Ashley Budu-Aggrey David Carslake Gibran Hemani Lavinia Paternoster George Davey Smith Neil Davies Daniel J Lawson Nicholas J Timpson

Nat Commun 2019 01 18;10(1):333. Epub 2019 Jan 18.

Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1038/s41467-018-08219-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338768PMC
January 2019

Assessing the effectiveness of dialkylcarbamoylchloride (DACC)-coated post-operative dressings versus standard care in the prevention of surgical site infection in clean or clean-contaminated, vascular surgery (the DRESSINg trial): study protocol for a pilot feasibility randomised controlled trial.

Authors:
Joshua P Totty Amy E Harwood Paris L Cai Louise H Hitchman George E Smith Ian C Chetter

Pilot Feasibility Stud 2019 18;5:11. Epub 2019 Jan 18.

Academic Vascular Surgical Unit, Hull Royal Infirmary, Anlaby Road, Hull, HU3 2JZ UK.

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http://dx.doi.org/10.1186/s40814-019-0400-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337832PMC
January 2019

Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis.

Authors:
Sean A Pymer Garry A Tew Joanne Palmer Lee Ingle George E Smith Ian C Chetter Amy E Harwood

SAGE Open Med 2018 10;6:2050312118818295. Epub 2018 Dec 10.

Academic Vascular Surgical Unit, Hull, UK.

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http://dx.doi.org/10.1177/2050312118818295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295772PMC
December 2018

Cognition, psychosis risk and metabolic measures in two adolescent birth cohorts.

Authors:
Hugh Ramsay Jennifer H Barnett Graham K Murray Jouko Miettunen Pirjo Mäki Marjo-Riitta Järvelin George Davey Smith Mika Ala-Korpela Juha Veijola

Psychol Med 2018 11 24;48(15):2609-2623. Epub 2018 Jul 24.

Department of Psychiatry,Research Unit of Clinical Neuroscience, University of Oulu,Oulu,Finland.

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November 2018

Cognition, psychosis risk and metabolic measures in two adolescent birth cohorts - CORRIGENDUM.

Authors:
Hugh Ramsay Jennifer H Barnett Graham K Murray Jouko Miettunen Pirjo Mäki Marjo-Riitta Järvelin George Davey Smith Mika Ala-Korpela Juha Veijola

Psychol Med 2018 11 30;48(15):2628. Epub 2018 Aug 30.

Department of Psychiatry,Research Unit of Clinical Neuroscience, University of Oulu,Oulu,Finland.

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http://dx.doi.org/10.1017/S0033291718002192DOI Listing
November 2018

ProDiet: A Phase II Randomized Placebo-controlled Trial of Green Tea Catechins and Lycopene in Men at Increased Risk of Prostate Cancer.

Authors:
J Athene Lane Vanessa Er Kerry N L Avery Jeremy Horwood Marie Cantwell Gema P Caro Alan Crozier George Davey Smith Jenny L Donovan Liz Down Freddie C Hamdy David Gillatt Jeff Holly Rhiannon Macefield Hilary Moody David E Neal Eleanor Walsh Richard M Martin Chris Metcalfe

Cancer Prev Res (Phila) 2018 11 11;11(11):687-696. Epub 2018 Oct 11.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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November 2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

CRISPR editing validation, immunostaining and DNA sequencing of individual fixed bovine embryos.

Authors:
Bradford W Daigneault Marcela Vilarino Sandeep K Rajput Tristan Frum George W Smith Pablo J Ross

Biotechniques 2018 11;65(5):281-283

Department of Animal Science, University of California - Davis, Davis, CA, USA.

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https://www.future-science.com/doi/10.2144/btn-2018-0051
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November 2018

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

Authors:
David L Duffy Gu Zhu Xin Li Marianna Sanna Mark M Iles Leonie C Jacobs David M Evans Seyhan Yazar Jonathan Beesley Matthew H Law Peter Kraft Alessia Visconti John C Taylor Fan Liu Margaret J Wright Anjali K Henders Lisa Bowdler Dan Glass M Arfan Ikram André G Uitterlinden Pamela A Madden Andrew C Heath Elliot C Nelson Adele C Green Stephen Chanock Jennifer H Barrett Matthew A Brown Nicholas K Hayward Stuart MacGregor Richard A Sturm Alex W Hewitt Manfred Kayser David J Hunter Julia A Newton Bishop Timothy D Spector Grant W Montgomery David A Mackey George Davey Smith Tamar E Nijsten D Timothy Bishop Veronique Bataille Mario Falchi Jiali Han Nicholas G Martin

Nat Commun 2018 11 14;9(1):4774. Epub 2018 Nov 14.

QIMR Berghofer Medical Research Institute, Brisbane, Australia.

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http://www.nature.com/articles/s41467-018-06649-5
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235897PMC
November 2018

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Authors:
Eeva Sliz Johannes Kettunen Michael Holmes Clare Williams Charles Boachie Qin Wang Minna Männikkö Sylvain Sebert Robin Walters Kuang Lin Lona Millwood Robert Clarke Liming Li N Rankin Paul Welsh Christian Delles J Jukema Stella Trompet Ian Ford Markus Perola Veikko Salomaa Marjo-Riitta Järvelin Zhengming Chen Debbie Lawlor Mika Ala-Korpela John Danesh George Smith Naveed Sattar Adam Butterworth Peter Würtz

Circulation 2018 Nov;138(22):2499–2512

Diabetes and Obesity Research Program, University of Helsinki, Finland

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254781PMC
November 2018

Extracorporeal shockwave therapy for intermittent claudication: Medium-term outcomes from a double-blind randomised placebo-controlled pilot trial.

Authors:
Jordan Luke Green Amy Elizabeth Harwood George Edward Smith Tushar Das Ali Raza Thomas Cayton Tom Wallace Daniel Carradice Ian Clifford Chetter

Vascular 2018 Oct 3;26(5):531-539. Epub 2018 May 3.

Academic Vascular Surgical Unit, Hull York Medical School/University of Hull, Hull, UK.

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http://dx.doi.org/10.1177/1708538118773618DOI Listing
October 2018

Cell-specific gene therapy driven by an optimized hypoxia-regulated vector reduces choroidal neovascularization.

Authors:
Manas R Biswal Howard M Prentice George W Smith Ping Zhu Yao Tong C Kathleen Dorey Alfred S Lewin Janet C Blanks

J Mol Med (Berl) 2018 10 13;96(10):1107-1118. Epub 2018 Aug 13.

Integrative Biology Program, Dept. of Biology, Florida Atlantic University, Boca Raton, FL, USA.

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http://dx.doi.org/10.1007/s00109-018-1683-0DOI Listing
October 2018

Testing the validity of value-added measures of educational progress with genetic data.

Authors:
Tim T Morris Neil M Davies Danny Dorling Rebecca C Richmond George Davey Smith

Br Educ Res J 2018 Oct 9;44(5):725-747. Epub 2018 Sep 9.

University of Bristol UK.

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http://dx.doi.org/10.1002/berj.3466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448053PMC
October 2018

Follistatin supplementation during in vitro embryo culture improves developmental competence of bovine embryos produced using sex-sorted semen.

Authors:
Mohamed Ashry KyungBon Lee Joseph K Folger Sandeep K Rajput George W Smith

Reprod Biol 2018 Sep 29;18(3):267-273. Epub 2018 Jun 29.

Laboratory of Mammalian Reproductive Biology and Genomics, Department of Animal Science, Reproductive and Developmental Sciences Program, Michigan State University, East Lansing, MI, 48824, USA. Electronic address:

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http://dx.doi.org/10.1016/j.repbio.2018.06.004DOI Listing
September 2018

Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery.

Authors:
Ying Wang Wei Wu Xiangbing Wu Yan Sun Yi P Zhang Ling-Xiao Deng Melissa Jane Walker Wenrui Qu Chen Chen Nai-Kui Liu Qi Han Heqiao Dai Lisa Be Shields Christopher B Shields Dale R Sengelaub Kathryn J Jones George M Smith Xiao-Ming Xu

Elife 2018 09 12;7. Epub 2018 Sep 12.

Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, United States.

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http://dx.doi.org/10.7554/eLife.39016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170189PMC
September 2018

Molecular genetic overlap between migraine and major depressive disorder.

Authors:
Yuanhao Yang Huiying Zhao Dorret I Boomsma Lannie Ligthart Andrea C Belin George Davey Smith Tonu Esko Tobias M Freilinger Thomas Folkmann Hansen M Arfan Ikram Mikko Kallela Christian Kubisch Christofidou Paraskevi David P Strachan Maija Wessman Arn M J M van den Maagdenberg Gisela M Terwindt Dale R Nyholt

Eur J Hum Genet 2018 08 11;26(8):1202-1216. Epub 2018 Jul 11.

Statistical and Genomic Epidemiology Laboratory, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1038/s41431-018-0150-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057914PMC
August 2018

Investigating the genetic architecture of general and specific psychopathology in adolescence.

Authors:
Hannah J Jones Jon Heron Gemma Hammerton Jan Stochl Peter B Jones Mary Cannon George Davey Smith Peter Holmans Glyn Lewis David E J Linden Michael C O'Donovan Michael J Owen James Walters Stanley Zammit

Transl Psychiatry 2018 08 8;8(1):145. Epub 2018 Aug 8.

Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41398-018-0204-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082910PMC
August 2018

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics.

Authors:
Jie Zheng Tom G Richardson Louise A C Millard Gibran Hemani Benjamin L Elsworth Christopher A Raistrick Bjarni Vilhjalmsson Benjamin M Neale Philip C Haycock George Davey Smith Tom R Gaunt

Gigascience 2018 08 1;7(8). Epub 2018 Aug 1.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1093/gigascience/giy090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109640PMC
August 2018

The association between BMI and mortality using early adulthood BMI as an instrumental variable for midlife BMI.

Authors:
Marte K R Kjøllesdal George Davey Smith Inger Ariansen Jonas Minet Kinge Eirik Degerud Øyvind Næss

Sci Rep 2018 07 31;8(1):11499. Epub 2018 Jul 31.

Institute of Health and Society, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1038/s41598-018-29089-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068135PMC
July 2018

Education and myopia: assessing the direction of causality by mendelian randomisation.

Authors:
Edward Mountjoy Neil M Davies Denis Plotnikov George Davey Smith Santiago Rodriguez Cathy E Williams Jeremy A Guggenheim Denize Atan

BMJ 2018 06 6;361:k2022. Epub 2018 Jun 6.

Translational Health Sciences, Bristol Medical School, University of Bristol, Biomedical Sciences Building, Bristol BS8 1TD, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987847PMC
http://dx.doi.org/10.1136/bmj.k2022DOI Listing
June 2018

Follistatin Rescues Blastocyst Development of Poor Quality Porcine Cumulus-Oocyte Complexes by Delaying Meiotic Resumption With Decreased cGMP.

Authors:
Bo Myeong Lee Ju Lan Chun Ji Hye Lee Eun Young Kim Kang-Sun Park Jin-Hee Lee Bradford W Daigneault George W Smith Keun Jung Kim Kyu-Tae Chang Sang-Rae Lee Sun-Uk Kim Seon-A Choi Kyung-Bon Lee Min Kyu Kim

Reprod Sci 2018 05 28;25(5):759-772. Epub 2017 Aug 28.

1 Department of Animal Science and Biotechnology, College of Agriculture and Life Science, Chungnam National University, Yuseong-gu, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1177/1933719117725829DOI Listing
May 2018

Cell-type specific expression of constitutively-active Rheb promotes regeneration of bulbospinal respiratory axons following cervical SCI.

Authors:
Mark W Urban Biswarup Ghosh Laura R Strojny Cole G Block Sara M Blazejewski Megan C Wright George M Smith Angelo C Lepore

Exp Neurol 2018 05 14;303:108-119. Epub 2018 Feb 14.

Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College, Thomas Jefferson University, 233 South 10th Street, BLSB 245, Philadelphia, PA 19107, United States. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2018.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864549PMC
May 2018

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.

Authors:
Pirro G Hysi Ana M Valdes Fan Liu Nicholas A Furlotte David M Evans Veronique Bataille Alessia Visconti Gibran Hemani George McMahon Susan M Ring George Davey Smith David L Duffy Gu Zhu Scott D Gordon Sarah E Medland Bochao D Lin Gonneke Willemsen Jouke Jan Hottenga Dragana Vuckovic Giorgia Girotto Ilaria Gandin Cinzia Sala Maria Pina Concas Marco Brumat Paolo Gasparini Daniela Toniolo Massimiliano Cocca Antonietta Robino Seyhan Yazar Alex W Hewitt Yan Chen Changqing Zeng Andre G Uitterlinden M Arfan Ikram Merel A Hamer Cornelia M van Duijn Tamar Nijsten David A Mackey Mario Falchi Dorret I Boomsma Nicholas G Martin David A Hinds Manfred Kayser Timothy D Spector

Nat Genet 2018 05 16;50(5):652-656. Epub 2018 Apr 16.

King's College London Department of Twins Research and Genetic Epidemiology, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0100-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935237PMC
May 2018

Response by Labos et al to Letter Regarding Article, "Evaluation of the Pleiotropic Effects of Statins: A Reanalysis of the Randomized Trial Evidence Using Egger Regression".

Authors:
Christopher Labos James M Brophy George Davey Smith Allan D Sniderman George Thanassoulis

Arterioscler Thromb Vasc Biol 2018 05;38(5):e87-e88

Division of Cardiology, McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1161/ATVBAHA.118.310907DOI Listing
May 2018

Embryonic POU5F1 is Required for Expanded Bovine Blastocyst Formation.

Authors:
Bradford W Daigneault Sandeep Rajput George W Smith Pablo J Ross

Sci Rep 2018 05 17;8(1):7753. Epub 2018 May 17.

Department of Animal Science, University of California Davis, Davis, CA, USA.

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http://www.nature.com/articles/s41598-018-25964-x
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http://dx.doi.org/10.1038/s41598-018-25964-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958112PMC
May 2018

Guiding People to Interpret Their Experienced Difficulty as Importance Highlights Their Academic Possibilities and Improves Their Academic Performance.

Authors:
Daphna Oyserman Kristen Elmore Sheida Novin Oliver Fisher George C Smith

Front Psychol 2018 25;9:781. Epub 2018 May 25.

Department of Psychology, Institute for Social Research, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fpsyg.2018.00781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983065PMC
May 2018

Closing the gap on Achilles tendon rupture: A cadaveric study quantifying the tendon apposition achieved with commonly used immobilisation practices.

Authors:
Ruaraidh Collins Alexis Sudlow Constantinos Loizou David T Loveday George Smith

Foot Ankle Surg 2018 Apr 23;24(2):124-127. Epub 2017 Jan 23.

Norfolk and Norwich University Hospital, Norwich, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S12687731173001
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http://dx.doi.org/10.1016/j.fas.2016.12.006DOI Listing
April 2018

Dispersal: a matter of scale.

Authors:
Elise R Morton Michael J McGrady Ian Newton Chris J Rollie George D Smith Richard Mearns Madan K Oli

Ecology 2018 04 6;99(4):938-946. Epub 2018 Mar 6.

Department of Wildlife Ecology and Conservation, School of Natural Resources and Environment, University of Florida, 110 Newins-Ziegler Hall, Gainesville, Florida, 32611, USA.

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http://dx.doi.org/10.1002/ecy.2172DOI Listing
April 2018

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.

Authors:
Angela M Wood Stephen Kaptoge Adam S Butterworth Peter Willeit Samantha Warnakula Thomas Bolton Ellie Paige Dirk S Paul Michael Sweeting Stephen Burgess Steven Bell William Astle David Stevens Albert Koulman Randi M Selmer W M Monique Verschuren Shinichi Sato Inger Njølstad Mark Woodward Veikko Salomaa Børge G Nordestgaard Bu B Yeap Astrid Fletcher Olle Melander Lewis H Kuller Beverley Balkau Michael Marmot Wolfgang Koenig Edoardo Casiglia Cyrus Cooper Volker Arndt Oscar H Franco Patrik Wennberg John Gallacher Agustín Gómez de la Cámara Henry Völzke Christina C Dahm Caroline E Dale Manuela M Bergmann Carlos J Crespo Yvonne T van der Schouw Rudolf Kaaks Leon A Simons Pagona Lagiou Josje D Schoufour Jolanda M A Boer Timothy J Key Beatriz Rodriguez Conchi Moreno-Iribas Karina W Davidson James O Taylor Carlotta Sacerdote Robert B Wallace J Ramon Quiros Rosario Tumino Dan G Blazer Allan Linneberg Makoto Daimon Salvatore Panico Barbara Howard Guri Skeie Timo Strandberg Elisabete Weiderpass Paul J Nietert Bruce M Psaty Daan Kromhout Elena Salamanca-Fernandez Stefan Kiechl Harlan M Krumholz Sara Grioni Domenico Palli José M Huerta Jackie Price Johan Sundström Larraitz Arriola Hisatomi Arima Ruth C Travis Demosthenes B Panagiotakos Anna Karakatsani Antonia Trichopoulou Tilman Kühn Diederick E Grobbee Elizabeth Barrett-Connor Natasja van Schoor Heiner Boeing Kim Overvad Jussi Kauhanen Nick Wareham Claudia Langenberg Nita Forouhi Maria Wennberg Jean-Pierre Després Mary Cushman Jackie A Cooper Carlos J Rodriguez Masaru Sakurai Jonathan E Shaw Matthew Knuiman Trudy Voortman Christa Meisinger Anne Tjønneland Hermann Brenner Luigi Palmieri Jean Dallongeville Eric J Brunner Gerd Assmann Maurizio Trevisan Richard F Gillum Ian Ford Naveed Sattar Mariana Lazo Simon G Thompson Pietro Ferrari David A Leon George Davey Smith Richard Peto Rod Jackson Emily Banks Emanuele Di Angelantonio John Danesh

Lancet 2018 04;391(10129):1513-1523

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)30134-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899998PMC
April 2018

The role of mitochondria in axon development and regeneration.

Authors:
George M Smith Gianluca Gallo

Dev Neurobiol 2018 03 24;78(3):221-237. Epub 2017 Oct 24.

Department of Anatomy and Cell Biology, Temple University, Lewis Katz School of Medicine, Philadelphia, Pennsylvania, 19140.

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http://dx.doi.org/10.1002/dneu.22546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816701PMC
March 2018

Use of photograph-based telemedicine in postoperative wound assessment to diagnose or exclude surgical site infection.

Authors:
Joshua P Totty Amy E Harwood Tom Wallace George E Smith Ian C Chetter

J Wound Care 2018 03;27(3):128-135

Professor of Surgery and Consultant in Vascular Surgery, Academic Vascular Surgical Unit, Hull Royal Infirmary, Anlaby Road, Hull.

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http://dx.doi.org/10.12968/jowc.2018.27.3.128DOI Listing
March 2018

A feasibility double-blind randomized placebo-controlled trial of extracorporeal shockwave therapy as a novel treatment for intermittent claudication.

Authors:
Amy Elizabeth Harwood Jordan Green Thomas Cayton Ali Raza Tom Wallace Daniel Carradice Ian Clifford Chetter George Edward Smith

J Vasc Surg 2018 02 22;67(2):514-521.e2. Epub 2017 Sep 22.

Academic Vascular Surgery Unit, Hull York Medical School, University of Hull, Hull, United Kingdom.

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http://dx.doi.org/10.1016/j.jvs.2017.07.105DOI Listing
February 2018

Characterization of H3.3 and HIRA expression and function in bovine early embryos.

Authors:
Kun Zhang Han Wang Sandeep K Rajput Joseph K Folger George W Smith

Mol Reprod Dev 2018 02 9;85(2):106-116. Epub 2018 Jan 9.

Laboratory of Mammalian Reproductive Biology and Genomics, Michigan State University, East Lansing, Michigan.

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http://dx.doi.org/10.1002/mrd.22939DOI Listing
February 2018

Biased Estimates in Mendelian Randomization Studies Conducted in Unrepresentative Samples.

Authors:
Marcus Munafò George Davey Smith

JAMA Cardiol 2018 02;3(2):181

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1001/jamacardio.2017.4279DOI Listing
February 2018

A comparative prospective cohort health economic analysis comparing ankle fusion, isolated great toe fusion and hallux valgus surgery.

Authors:
David T Loveday Lynne V Barr Constantinos L Loizou Garry Barton George Smith

Foot Ankle Surg 2018 Feb 25;24(1):54-59. Epub 2016 Nov 25.

Norfolk & Norwich University Hospital, Colney Lane, Norwich NR4 7UY, UK.

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http://dx.doi.org/10.1016/j.fas.2016.11.008DOI Listing
February 2018

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

Authors:
Laura J Corbin Vanessa Y Tan David A Hughes Kaitlin H Wade Dirk S Paul Katherine E Tansey Frances Butcher Frank Dudbridge Joanna M Howson Momodou W Jallow Catherine John Nathalie Kingston Cecilia M Lindgren Michael O'Donavan Stephen O'Rahilly Michael J Owen Colin N A Palmer Ewan R Pearson Robert A Scott David A van Heel John Whittaker Tim Frayling Martin D Tobin Louise V Wain George Davey Smith David M Evans Fredrik Karpe Mark I McCarthy John Danesh Paul W Franks Nicholas J Timpson

Nat Commun 2018 02 19;9(1):711. Epub 2018 Feb 19.

MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1038/s41467-018-03109-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818506PMC
February 2018

Maternal thyroid function and child educational attainment: prospective cohort study.

Authors:
Scott M Nelson Caroline Haig Alex McConnachie Naveed Sattar Susan M Ring George D Smith Debbie A Lawlor Robert S Lindsay

BMJ 2018 02 20;360:k452. Epub 2018 Feb 20.

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819484PMC
http://dx.doi.org/10.1136/bmj.k452DOI Listing
February 2018

Editorial: Gene Therapy for the Central and Peripheral Nervous System.

Authors:
Andrew P Tosolini George M Smith

Front Mol Neurosci 2018 22;11:54. Epub 2018 Feb 22.

Department of Neuroscience, Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fnmol.2018.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829609PMC
February 2018

Partitioning Phenotypic Variance Due to Parent-of-Origin Effects Using Genomic Relatedness Matrices.

Authors:
Charles Laurin Gabriel Cuellar-Partida Gibran Hemani George Davey Smith Jian Yang David M Evans

Behav Genet 2018 01 2;48(1):67-79. Epub 2017 Nov 2.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1007/s10519-017-9880-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752821PMC
January 2018

Evaluation of the Pleiotropic Effects of Statins: A Reanalysis of the Randomized Trial Evidence Using Egger Regression-Brief Report.

Authors:
Christopher Labos James M Brophy George Davey Smith Allan D Sniderman George Thanassoulis

Arterioscler Thromb Vasc Biol 2018 01 9;38(1):262-265. Epub 2017 Nov 9.

From the Preventive and Genomic Cardiology, Division of Cardiology, McGill University Health Centre and Research Institute, Montreal, QC, Canada (C.L., J.M.B., A.D.S., G.T.); Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada (J.M.B.); and MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (G.D.S.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310052DOI Listing
January 2018

Functional role of AKT signaling in bovine early embryonic development: potential link to embryotrophic actions of follistatin.

Authors:
Mohamed Ashry Sandeep K Rajput Joseph K Folger Jason G Knott Nabil A Hemeida Omaima M Kandil Refaat S Ragab George W Smith

Reprod Biol Endocrinol 2018 Jan 8;16(1). Epub 2018 Jan 8.

Laboratory of Mammalian Reproductive Biology and Genomics, Michigan State University, East Lansing, MI, 48824, USA.

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http://dx.doi.org/10.1186/s12958-017-0318-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759257PMC
January 2018

Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans.

Authors:
Yoonsu Cho Soyoung Kwak Sarah J Lewis Kaitlin H Wade Caroline L Relton George Davey Smith Min-Jeong Shin

Sci Rep 2018 01 11;8(1):458. Epub 2018 Jan 11.

Department of Public Health Sciences, BK21PLUS Program in Embodiment: Health-Society Interaction, Graduate School, Korea University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-017-18856-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765011PMC
January 2018

Expression of a Peptidoglycan Hydrolase from Lytic Bacteriophages Atu_ph02 and Atu_ph03 Triggers Lysis of Agrobacterium tumefaciens.

Authors:
Hedieh Attai Jeanette Rimbey George P Smith Pamela J B Brown

Appl Environ Microbiol 2017 Dec 16;83(23). Epub 2017 Nov 16.

Division of Biological Sciences, University of Missouri, Columbia, Missouri, USA

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http://dx.doi.org/10.1128/AEM.01498-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691410PMC
December 2017

Biomechanical Comparison of Intramedullary Fibular Nail Versus Plate and Screw Fixation.

Authors:
George Smith Samuel Peter Mackenzie Robert James Wallace Tom Carter Timothy Oliver White

Foot Ankle Int 2017 Dec 3;38(12):1394-1399. Epub 2017 Oct 3.

2 Department of Trauma and Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1177/1071100717731757DOI Listing
December 2017

To mdivi-1 or not to mdivi-1: Is that the question?

Authors:
George Smith Gianluca Gallo

Dev Neurobiol 2017 11 30;77(11):1260-1268. Epub 2017 Aug 30.

Department of Anatomy and Cell Biology, Shriners Hospitals Pediatric Research Center, 3500 North Broad Street, Philadelphia, Pennsylvania, 19140.

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http://dx.doi.org/10.1002/dneu.22519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654677PMC
November 2017

Dyslipidaemia: Revealing the effect of CETP inhibition in cardiovascular disease.

Authors:
Michael V Holmes George Davey Smith

Nat Rev Cardiol 2017 Nov 5;14(11):635-636. Epub 2017 Oct 5.

Medical Research Council Integrative Epidemiology Unit and the National Institute for Health Research Bristol Biomedical Research Centre, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK; and the School of Social and Community Medicine, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1038/nrcardio.2017.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644574PMC
November 2017

Postinjury Induction of Activated ErbB2 Selectively Hyperactivates Denervated Schwann Cells and Promotes Robust Dorsal Root Axon Regeneration.

Authors:
Seung Baek Han Hyukmin Kim Hyunkyoung Lee Matthew Grove George M Smith Young-Jin Son

J Neurosci 2017 11 5;37(45):10955-10970. Epub 2017 Oct 5.

Shriners Hospitals Pediatric Research Center and Center for Neural Repair and Rehabilitation, Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania 19140

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http://dx.doi.org/10.1523/JNEUROSCI.0903-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678025PMC
November 2017

Recent Developments in Mendelian Randomization Studies.

Authors:
Jie Zheng Denis Baird Maria-Carolina Borges Jack Bowden Gibran Hemani Philip Haycock David M Evans George Davey Smith

Curr Epidemiol Rep 2017 22;4(4):330-345. Epub 2017 Nov 22.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Bristol, UK.

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http://dx.doi.org/10.1007/s40471-017-0128-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711966PMC
November 2017

A systematic review of muscle morphology and function in intermittent claudication.

Authors:
Amy E Harwood Stephanie King Joshua Totty George E Smith Natalie Vanicek Ian C Chetter

J Vasc Surg 2017 10 16;66(4):1241-1257. Epub 2017 Aug 16.

Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S07415214173162
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http://dx.doi.org/10.1016/j.jvs.2017.05.106DOI Listing
October 2017

Functional Role of Cyclin-Dependent Kinase 5 in the Regulation of Melanogenesis and Epidermal Structure.

Authors:
Changsheng Dong Shanshan Yang Ruiwen Fan Kaiyuan Ji Junzhen Zhang Xuexian Liu Shuaipeng Hu Jianshan Xie Yu Liu Wenjun Gao Haidong Wang Jianbo Yao George W Smith Muren Herrid

Sci Rep 2017 10 23;7(1):13783. Epub 2017 Oct 23.

College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801, China.

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http://dx.doi.org/10.1038/s41598-017-12567-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653820PMC
October 2017

"Intermittent claudication a real pain in the calf"-Patient experience of diagnosis and treatment with a supervised exercise program.

Authors:
Amy-Elizabeth Harwood Edward Broadbent Joshua Phillip Totty George Edward Smith Ian Clifford Chetter

J Vasc Nurs 2017 Sep;35(3):131-135

Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, United Kingdom.

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http://dx.doi.org/10.1016/j.jvn.2017.03.001DOI Listing
September 2017

Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk.

Authors:
Brian A Ference John J P Kastelein Henry N Ginsberg M John Chapman Stephen J Nicholls Kausik K Ray Chris J Packard Ulrich Laufs Robert D Brook Clare Oliver-Williams Adam S Butterworth John Danesh George Davey Smith Alberico L Catapano Marc S Sabatine

JAMA 2017 09;318(10):947-956

Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2017.11467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710502PMC
September 2017

Association of pre-pregnancy body mass index with offspring metabolic profile: Analyses of 3 European prospective birth cohorts.

Authors:
Diana L Santos Ferreira Dylan M Williams Antti J Kangas Pasi Soininen Mika Ala-Korpela George Davey Smith Marjo-Riitta Jarvelin Debbie A Lawlor

PLoS Med 2017 Aug 22;14(8):e1002376. Epub 2017 Aug 22.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568725PMC
August 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Authors:
Mariaelisa Graff Robert A Scott Anne E Justice Kristin L Young Mary F Feitosa Llilda Barata Thomas W Winkler Audrey Y Chu Anubha Mahajan David Hadley Luting Xue Tsegaselassie Workalemahu Nancy L Heard-Costa Marcel den Hoed Tarunveer S Ahluwalia Qibin Qi Julius S Ngwa Frida Renström Lydia Quaye John D Eicher James E Hayes Marilyn Cornelis Zoltan Kutalik Elise Lim Jian'an Luan Jennifer E Huffman Weihua Zhang Wei Zhao Paula J Griffin Toomas Haller Shafqat Ahmad Pedro M Marques-Vidal Stephanie Bien Loic Yengo Alexander Teumer Albert Vernon Smith Meena Kumari Marie Neergaard Harder Johanne Marie Justesen Marcus E Kleber Mette Hollensted Kurt Lohman Natalia V Rivera John B Whitfield Jing Hua Zhao Heather M Stringham Leo-Pekka Lyytikäinen Charlotte Huppertz Gonneke Willemsen Wouter J Peyrot Ying Wu Kati Kristiansson Ayse Demirkan Myriam Fornage Maija Hassinen Lawrence F Bielak Gemma Cadby Toshiko Tanaka Reedik Mägi Peter J van der Most Anne U Jackson Jennifer L Bragg-Gresham Veronique Vitart Jonathan Marten Pau Navarro Claire Bellis Dorota Pasko Åsa Johansson Søren Snitker Yu-Ching Cheng Joel Eriksson Unhee Lim Mette Aadahl Linda S Adair Najaf Amin Beverley Balkau Juha Auvinen John Beilby Richard N Bergman Sven Bergmann Alain G Bertoni John Blangero Amélie Bonnefond Lori L Bonnycastle Judith B Borja Søren Brage Fabio Busonero Steve Buyske Harry Campbell Peter S Chines Francis S Collins Tanguy Corre George Davey Smith Graciela E Delgado Nicole Dueker Marcus Dörr Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Jessica D Faul Mao Fu Kristine Færch Christian Gieger Sven Gläser Jian Gong Penny Gordon-Larsen Harald Grallert Tanja B Grammer Niels Grarup Gerard van Grootheest Kennet Harald Nicholas D Hastie Aki S Havulinna Dena Hernandez Lucia Hindorff Lynne J Hocking Oddgeir L Holmens Christina Holzapfel Jouke Jan Hottenga Jie Huang Tao Huang Jennie Hui Cornelia Huth Nina Hutri-Kähönen Alan L James John-Olov Jansson Min A Jhun Markus Juonala Leena Kinnunen Heikki A Koistinen Ivana Kolcic Pirjo Komulainen Johanna Kuusisto Kirsti Kvaløy Mika Kähönen Timo A Lakka Lenore J Launer Benjamin Lehne Cecilia M Lindgren Mattias Lorentzon Robert Luben Michel Marre Yuri Milaneschi Keri L Monda Grant W Montgomery Marleen H M De Moor Antonella Mulas Martina Müller-Nurasyid A W Musk Reija Männikkö Satu Männistö Narisu Narisu Matthias Nauck Jennifer A Nettleton Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Lavinia Paternoster Jeremiah Perez Markus Perola Annette Peters Ulrike Peters Patricia A Peyser Inga Prokopenko Hannu Puolijoki Olli T Raitakari Tuomo Rankinen Laura J Rasmussen-Torvik Rajesh Rawal Paul M Ridker Lynda M Rose Igor Rudan Cinzia Sarti Mark A Sarzynski Kai Savonen William R Scott Serena Sanna Alan R Shuldiner Steve Sidney Günther Silbernagel Blair H Smith Jennifer A Smith Harold Snieder Alena Stančáková Barbara Sternfeld Amy J Swift Tuija Tammelin Sian-Tsung Tan Barbara Thorand Dorothée Thuillier Liesbeth Vandenput Henrik Vestergaard Jana V van Vliet-Ostaptchouk Marie-Claude Vohl Uwe Völker Gérard Waeber Mark Walker Sarah Wild Andrew Wong Alan F Wright M Carola Zillikens Niha Zubair Christopher A Haiman Loic Lemarchand Ulf Gyllensten Claes Ohlsson Albert Hofman Fernando Rivadeneira André G Uitterlinden Louis Pérusse James F Wilson Caroline Hayward Ozren Polasek Francesco Cucca Kristian Hveem Catharina A Hartman Anke Tönjes Stefania Bandinelli Lyle J Palmer Sharon L R Kardia Rainer Rauramaa Thorkild I A Sørensen Jaakko Tuomilehto Veikko Salomaa Brenda W J H Penninx Eco J C de Geus Dorret I Boomsma Terho Lehtimäki Massimo Mangino Markku Laakso Claude Bouchard Nicholas G Martin Diana Kuh Yongmei Liu Allan Linneberg Winfried März Konstantin Strauch Mika Kivimäki Tamara B Harris Vilmundur Gudnason Henry Völzke Lu Qi Marjo-Riitta Järvelin John C Chambers Jaspal S Kooner Philippe Froguel Charles Kooperberg Peter Vollenweider Göran Hallmans Torben Hansen Oluf Pedersen Andres Metspalu Nicholas J Wareham Claudia Langenberg David R Weir David J Porteous Eric Boerwinkle Daniel I Chasman Gonçalo R Abecasis Inês Barroso Mark I McCarthy Timothy M Frayling Jeffrey R O'Connell Cornelia M van Duijn Michael Boehnke Iris M Heid Karen L Mohlke David P Strachan Caroline S Fox Ching-Ti Liu Joel N Hirschhorn Robert J Klein Andrew D Johnson Ingrid B Borecki Paul W Franks Kari E North L Adrienne Cupples Ruth J F Loos Tuomas O Kilpeläinen

PLoS Genet 2017 Aug 23;13(8):e1006972. Epub 2017 Aug 23.

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http://dx.doi.org/10.1371/journal.pgen.1006972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567921PMC
August 2017