George S Charames

George S Charames

UNVERIFIED PROFILE

Are you George S Charames?   Register this Author

Register author
George S Charames

George S Charames

Publications by authors named "George S Charames"

Are you George S Charames?   Register this Author

20Publications

457Reads

37Profile Views

Variant classification changes over time in BRCA1 and BRCA2.

Genet Med 2019 Oct 11;21(10):2248-2254. Epub 2019 Apr 11.

Department of Pathology and Laboratory Medicine, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41436-019-0493-2DOI Listing
October 2019

Correction: Variant classification changes over time in BRCA1 and BRCA2.

Genet Med 2019 Oct;21(10):2406-2407

Department of Pathology and Laboratory Medicine, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41436-019-0526-xDOI Listing
October 2019

Proteome-wide onco-proteogenomic somatic variant identification in ER-positive breast cancer.

Clin Biochem 2019 Apr 23;66:63-75. Epub 2019 Jan 23.

Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, 600 University Avenue, Toronto, ON M5G 1X5, Canada; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 600 University Avenue, Toronto, ON M5G 1X5, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2019.01.005DOI Listing
April 2019

Epithelioid fibrous histiocytoma: molecular characterization of ALK fusion partners in 23 cases.

Mod Pathol 2018 05 12;31(5):753-762. Epub 2018 Jan 12.

Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/modpathol.2017.191
Publisher Site
http://dx.doi.org/10.1038/modpathol.2017.191DOI Listing
May 2018

Genetic biomarkers associated with response to palliative radiotherapy in patients with painful bone metastases.

Ann Palliat Med 2017 Dec 10;6(Suppl 2):S233-S239. Epub 2017 Oct 10.

Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2017.09.03DOI Listing
December 2017

Genetic biomarkers associated with changes in quality of life and pain following palliative radiotherapy in patients with bone metastases.

Ann Palliat Med 2017 Dec 28;6(Suppl 2):S248-S256. Epub 2017 Sep 28.

Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2017.09.01DOI Listing
December 2017

Genetic biomarkers associated with pain flare and dexamethasone response following palliative radiotherapy in patients with painful bone metastases.

Ann Palliat Med 2017 Dec 20;6(Suppl 2):S240-S247. Epub 2017 Sep 20.

Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/16557/18212
Publisher Site
http://dx.doi.org/10.21037/apm.2017.09.04DOI Listing
December 2017

Onco-proteogenomics: Multi-omics level data integration for accurate phenotype prediction.

Crit Rev Clin Lab Sci 2017 09 12;54(6):414-432. Epub 2017 Oct 12.

a Department of Laboratory Medicine and Pathobiology , University of Toronto , Toronto , ON , Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10408363.2017.1384446DOI Listing
September 2017

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Nat Genet 2015 Mar 2;47(3):257-62. Epub 2015 Feb 2.

1] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. [3] Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. [4] Department of Pediatrics, University of Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3202DOI Listing
March 2015

Rac1b recruits Dishevelled and β-catenin to Wnt target gene promoters independent of Wnt3A stimulation.

Int J Oncol 2011 Oct 6;39(4):805-10. Epub 2011 Jun 6.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, M5T 3L9, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2011.1066DOI Listing
October 2011

Suppression of nuclear Wnt signaling leads to stabilization of Rac1 isoforms.

FEBS Lett 2007 Oct 17;581(25):4850-6. Epub 2007 Sep 17.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Room L6-304-4, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2007.09.013DOI Listing
October 2007

Cyclooxygenase-2 knockdown by RNA interference in colon cancer.

Int J Oncol 2006 Feb;28(2):543-9

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
February 2006

Genomic instability and cancer.

Curr Mol Med 2003 Nov;3(7):589-96

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1566524033479456DOI Listing
November 2003