Publications by authors named "George R Washko"

100Publications

The Framingham Heart Study: Populational CT-based phenotyping in the lungs and mediastinum.

Eur J Radiol Open 2020 11;7:100260. Epub 2020 Sep 11.

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ejro.2020.100260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495061PMC
September 2020

Pulmonary Vascular Pruning on Computed Tomography and Risk of Death in the Framingham Heart Study.

Am J Respir Crit Care Med 2020 Sep 14. Epub 2020 Sep 14.

Beth Israel Deaconess Medical Center, Division of Pulmonary, Critical Care and Sleep Medicine, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1164/rccm.202005-1671LEDOI Listing
September 2020

Computerized Chest Imaging in the Diagnosis and Assessment of the Patient with Chronic Obstructive Pulmonary Disease.

Clin Chest Med 2020 09;41(3):375-381

Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ccm.2020.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454015PMC
September 2020

Vascular Pruning on CT and Interstitial Lung Abnormalities in the Framingham Heart Study.

Chest 2020 Aug 14. Epub 2020 Aug 14.

Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.chest.2020.07.082DOI Listing
August 2020

A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells.

Stem Cell Reports 2020 07 2;15(1):242-255. Epub 2020 Jul 2.

Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2020.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363960PMC
July 2020

Evidence for Expanding Invasive Mediastinal Staging for Peripheral T1 Lung Tumors.

Chest 2020 Nov 26;158(5):2192-2199. Epub 2020 Jun 26.

Division of Pulmonary and Critical Care, University of Vermont Medical Center, Burlington, VT. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2020.05.607DOI Listing
November 2020

Lung Function and Gene Expression of Pathogen Recognition Pathway Receptors: the Cardia Lung Study.

Sci Rep 2020 06 9;10(1):9360. Epub 2020 Jun 9.

Department of Pathology and Laboratory Medicine, University of Minnesota School of Medicine, Minneapolis, MN, USA.

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http://dx.doi.org/10.1038/s41598-020-65923-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283270PMC
June 2020

Bronchial Cartilage Assessment with Model-Based GAN Regressor.

Med Image Comput Comput Assist Interv 2019 Oct 10;11769:357-365. Epub 2019 Oct 10.

Applied Chest Imaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-3-030-32226-7_40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266165PMC
October 2019

LOCALIZING IMAGE-BASED BIOMARKER REGRESSION WITHOUT TRAINING MASKS: A NEW APPROACH TO BIOMARKER DISCOVERY.

Proc IEEE Int Symp Biomed Imaging 2019 Apr 11;2019:679-682. Epub 2019 Jul 11.

Applied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School. USA.

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http://dx.doi.org/10.1109/isbi.2019.8759474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243964PMC
April 2019

Smaller Left Ventricle Size at Noncontrast CT Is Associated with Lower Mortality in COPDGene Participants.

Radiology 2020 Jul 5;296(1):208-215. Epub 2020 May 5.

From the Division of Pulmonary and Critical Care, Department of Medicine, Applied Chest Imaging Laboratory (G.R.W., S.Y.A., F.N.R., C.E.C., C.L.P., A.A.D.), Department of Radiology, Applied Chest Imaging Laboratory (P.N., G.V.S.F., J.C.R., R.S.J.E.), Department of Anesthesia (G.Q.R.), and Division of Cardiology (A.M.S.), Brigham and Women's Hospital, 1249 Boylston St, Boston, MA 02215; Lung Health Center, University of Alabama at Birmingham, Birmingham, Ala (M.T.D., S.P.B., J.M.W.); Asthma and COPD Program, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (R.K.); Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Mich (M.K.H.); BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom (S.R.), Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Neb (S.R.); Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colo (K.Y., G.L.K., J.E.H.); and Respiratory Institute, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute, Centro de Investigación Biomédica en Red Enfermedades Respiratorias, University of Barcelona, Barcelona, Spain (A.A.).

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http://dx.doi.org/10.1148/radiol.2020191793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299752PMC
July 2020

Machine Learning and Prediction of All-Cause Mortality in COPD.

Chest 2020 Sep 27;158(3):952-964. Epub 2020 Apr 27.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2020.02.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478228PMC
September 2020

Cost-effectiveness microsimulation of catheter-directed thrombolysis in submassive pulmonary embolism using a right ventricular function model.

J Thromb Thrombolysis 2020 May;49(4):673-680

Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1007/s11239-020-02058-yDOI Listing
May 2020

Classification of Interstitial Lung Abnormality Patterns with an Ensemble of Deep Convolutional Neural Networks.

Sci Rep 2020 01 15;10(1):338. Epub 2020 Jan 15.

Biomedical Image Technologies, ETSI Telecomunicación, Universidad Politécnica de Madrid & CIBER-BBN, Madrid, Spain.

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http://dx.doi.org/10.1038/s41598-019-56989-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962320PMC
January 2020

COPDGene 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease.

Authors:
Katherine E Lowe Elizabeth A Regan Antonio Anzueto Erin Austin John H M Austin Terri H Beaty Panayiotis V Benos Christopher J Benway Surya P Bhatt Eugene R Bleecker Sandeep Bodduluri Jessica Bon Aladin M Boriek Adel Re Boueiz Russell P Bowler Matthew Budoff Richard Casaburi Peter J Castaldi Jean-Paul Charbonnier Michael H Cho Alejandro Comellas Douglas Conrad Corinne Costa Davis Gerard J Criner Douglas Curran-Everett Jeffrey L Curtis Dawn L DeMeo Alejandro A Diaz Mark T Dransfield Jennifer G Dy Ashraf Fawzy Margaret Fleming Eric L Flenaugh Marilyn G Foreman Spyridon Fortis Hirut Gebrekristos Sarah Grant Philippe A Grenier Tian Gu Abhya Gupta MeiLan K Han Nicola A Hanania Nadia N Hansel Lystra P Hayden Craig P Hersh Brian D Hobbs Eric A Hoffman James C Hogg John E Hokanson Karin F Hoth Albert Hsiao Stephen Humphries Kathleen Jacobs Francine L Jacobson Ella A Kazerooni Victor Kim Woo Jin Kim Gregory L Kinney Harald Koegler Sharon M Lutz David A Lynch Neil R MacIntye Barry J Make Nathaniel Marchetti Fernando J Martinez Diego J Maselli Anne M Mathews Meredith C McCormack Merry-Lynn N McDonald Charlene E McEvoy Matthew Moll Sarah S Molye Susan Murray Hrudaya Nath John D Newell Mariaelena Occhipinti Matteo Paoletti Trisha Parekh Massimo Pistolesi Katherine A Pratte Nirupama Putcha Margaret Ragland Joseph M Reinhardt Stephen I Rennard Richard A Rosiello James C Ross Harry B Rossiter Ingo Ruczinski Raul San Jose Estepar Frank C Sciurba Jessica C Sieren Harjinder Singh Xavier Soler Robert M Steiner Matthew J Strand William W Stringer Ruth Tal-Singer Byron Thomashow Gonzalo Vegas Sánchez-Ferrero John W Walsh Emily S Wan George R Washko J Michael Wells Chris H Wendt Gloria Westney Ava Wilson Robert A Wise Andrew Yen Kendra Young Jeong Yun Edwin K Silverman James D Crapo

Chronic Obstr Pulm Dis 2019 Nov;6(5):384-399

National Jewish Health, Denver, Colorado.

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http://dx.doi.org/10.15326/jcopdf.6.5.2019.0149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020846PMC
November 2019

Adult Life-Course Trajectories of Lung Function and the Development of Emphysema: The CARDIA Lung Study.

Am J Med 2020 02 29;133(2):222-230.e11. Epub 2019 Jul 29.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.

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http://dx.doi.org/10.1016/j.amjmed.2019.06.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980254PMC
February 2020

Heart and lungs in a single breath.

Respirology 2019 10 11;24(10):937-938. Epub 2019 Jul 11.

Respiratory Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13641
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http://dx.doi.org/10.1111/resp.13641DOI Listing
October 2019

Radiographic pulmonary vessel volume, lung function and airways disease in the Framingham Heart Study.

Eur Respir J 2019 09 12;54(3). Epub 2019 Sep 12.

Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1183/13993003.00408-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173739PMC
September 2019

Harmonization of chest CT scans for different doses and reconstruction methods.

Med Phys 2019 Jul 7;46(7):3117-3132. Epub 2019 Jun 7.

Applied Chest Imaging Laboratory (ACIL), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/mp.13578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251983PMC
July 2019

Validation of Imaging Measures in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2019 Sep;200(5):524-525

Department of MedicineBrigham and Women's HospitalBoston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201902-0395EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727160PMC
September 2019

Rebuttal From Dr Washko.

Authors:
George R Washko

Chest 2018 12;154(6):1281-1282

Lung Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.08.1054DOI Listing
December 2018

POINT: Should Chest CT Be Part of Routine Clinical Care for COPD? Yes.

Authors:
George R Washko

Chest 2018 12;154(6):1276-1278

Lung Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.08.1053DOI Listing
December 2018

COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging.

Eur Respir J 2018 11 29;52(5). Epub 2018 Nov 29.

Robarts Research Institute, Western University, London, ON, Canada.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01570
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http://dx.doi.org/10.1183/13993003.01570-2018DOI Listing
November 2018

Multi-structure Segmentation from Partially Labeled Datasets. Application to Body Composition Measurements on CT Scans.

Image Anal Mov Organ Breast Thorac Images (2018) 2018 Sep 12;11040:215-224. Epub 2018 Sep 12.

Applied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-3-030-00946-5_22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269188PMC
September 2018

On the Relevance of the Loss Function in the Agatston Score Regression from Non-ECG Gated CT Scans.

Image Anal Mov Organ Breast Thorac Images (2018) 2018 Sep 12;11040:326-334. Epub 2018 Sep 12.

Applied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-3-030-00946-5_33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258442PMC
September 2018

Deep learning for biomarker regression: application to osteoporosis and emphysema on chest CT scans.

Proc SPIE Int Soc Opt Eng 2018 Feb 2;10574. Epub 2018 Mar 2.

Applied Chest Imaging Laboratory. Department of Radiology. Brigham and Women's Hospital. 1249 Boylston St, Boston MA, 02115.

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http://dx.doi.org/10.1117/12.2293455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097534PMC
February 2018

Automated Agatston Score Computation in non-ECG Gated CT Scans Using Deep Learning.

Proc SPIE Int Soc Opt Eng 2018 Feb 2;10574. Epub 2018 Mar 2.

Applied Chest Imaging Laboratory. Brigham and Women's Hospital. 1249 Boylston St. Boston. Massachusetts. United States.

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https://www.spiedigitallibrary.org/conference-proceedings-of
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http://dx.doi.org/10.1117/12.2293681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095680PMC
February 2018

Multiorgan structures detection using deep convolutional neural networks.

Proc SPIE Int Soc Opt Eng 2018 Feb 2;10574. Epub 2018 Mar 2.

Applied Chest Imaging Laboratory, Dept. of Radiology, Brigham and Women's Hospital, 1249 Boylston St, Boston, MA USA.

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http://dx.doi.org/10.1117/12.2293761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095667PMC
February 2018

Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort.

Radiology 2018 08 5;288(2):600-609. Epub 2018 Jun 5.

From the Division of Pulmonary and Critical Care Medicine, Department of Medicine (S.Y.A., A.A.D., F.N.R., R.K.P., G.M.H., I.O.R., G.R.W.), Laboratory of Mathematics in Imaging, Department of Radiology (R.H., J.C.R., G.V.S., J.O.O., R.S.J.E.), and Department of Radiology (H.H.), Brigham and Women's Hospital, 75 Francis St, PBB CA-3, Boston, MA 02115; Department of Medicine, Weil Cornell Medical College, New York, NY (F.J.M., A.M.C.); Departments of Medicine (R.P.B.) and Radiology (D.A.L.), National Jewish Health, Denver, Colo; and Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Ala (S.P.B., M.T.D., J.M.W.).

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http://dx.doi.org/10.1148/radiol.2018172688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069608PMC
August 2018

Pectoralis muscle area and mortality in smokers without airflow obstruction.

Respir Res 2018 04 10;19(1):62. Epub 2018 Apr 10.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12931-018-0771-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894181PMC
April 2018

Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine.

Am J Respir Crit Care Med 2018 08;198(4):440-446

1 Asthma and COPD Program, Division of Pulmonary and Critical Care Medicine, and.

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http://dx.doi.org/10.1164/rccm.201801-0120PPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118019PMC
August 2018

Susceptibility to Inhalational Lung Injury: We Need More Than the FEV.

Authors:
George R Washko

Ann Am Thorac Soc 2018 02;15(2):156-157

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1513/AnnalsATS.201711-870EDDOI Listing
February 2018

Autocalibration method for non-stationary CT bias correction.

Med Image Anal 2018 02 8;44:115-125. Epub 2017 Dec 8.

Applied Chest Imaging Laboratory (ACIL), Brigham and Women's Hospital, Harvard Medical School, 1249 Boylston St. 02115, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.media.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071427PMC
February 2018

CT imaging of chronic obstructive pulmonary disease: insights, disappointments, and promise.

Lancet Respir Med 2017 11 28;5(11):903-908. Epub 2017 Sep 28.

Division of Respirology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1016/S2213-2600(17)30345-4DOI Listing
November 2017

Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression.

Chest 2018 01 21;153(1):65-76. Epub 2017 Sep 21.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Division of General Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2017.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026264PMC
January 2018

Disease Staging and Prognosis in Smokers Using Deep Learning in Chest Computed Tomography.

Am J Respir Crit Care Med 2018 01;197(2):193-203

3 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston Massachusetts.

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http://dx.doi.org/10.1164/rccm.201705-0860OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768902PMC
January 2018

Imaging approaches to understand disease complexity: chronic obstructive pulmonary disease as a clinical model.

J Appl Physiol (1985) 2018 02 27;124(2):512-520. Epub 2017 Jul 27.

Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre , Maastricht , The Netherlands.

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http://www.physiology.org/doi/10.1152/japplphysiol.00143.201
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http://dx.doi.org/10.1152/japplphysiol.00143.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050198PMC
February 2018

Pulmonary Clinicopathological Correlation after Allogeneic Hematopoietic Stem Cell Transplantation: An Autopsy Series.

Biol Blood Marrow Transplant 2017 Oct 28;23(10):1767-1772. Epub 2017 Jun 28.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.bbmt.2017.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797990PMC
October 2017

Statistical characterization of noise for spatial standardization of CT scans: Enabling comparison with multiple kernels and doses.

Med Image Anal 2017 Aug 7;40:44-59. Epub 2017 Jun 7.

Applied Chest Imaging Laboratory (ACIL), Brigham and Women's Hospital, Harvard Medical School, 1249, Boylston St., Boston, MA 02115 USA.

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http://dx.doi.org/10.1016/j.media.2017.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742643PMC
August 2017

Pleural abnormalities in the Framingham Heart Study: prevalence and CT image features.

Occup Environ Med 2017 10 3;74(10):756-761. Epub 2017 May 3.

Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/oemed-2016-104178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701783PMC
October 2017

Ectopic fat accumulation in patients with COPD: an ECLIPSE substudy.

Int J Chron Obstruct Pulmon Dis 2017 31;12:451-460. Epub 2017 Jan 31.

Research Centre, Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, QC.

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http://dx.doi.org/10.2147/COPD.S124750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293362PMC
August 2017