George N Phillips

George N Phillips

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Resistance to Enediyne Antitumor Antibiotics by Sequestration.

Cell Chem Biol 2018 09 21;25(9):1075-1085.e4. Epub 2018 Jun 21.

Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL 33458, USA; Natural Products Library Initiative at The Scripps Research Institute, The Scripps Research Institute, Jupiter, FL 33458, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2018.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208323PMC
September 2018

Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.

ACS Chem Biol 2018 09 10;13(9):2728-2738. Epub 2018 Sep 10.

Department of Chemistry , The Scripps Research Institute , 130 Scripps Way , Jupiter , Florida 33458 , United States.

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http://dx.doi.org/10.1021/acschembio.8b00673DOI Listing
September 2018

Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.

ACS Omega 2017 Aug 30;2(8):5159-5169. Epub 2017 Aug 30.

Department of Chemistry, Department of Molecular Medicine, and Natural Products Library Initiative at The Scripps Research Institute, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.

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http://dx.doi.org/10.1021/acsomega.7b00933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579567PMC
August 2017

Structure and specificity of a permissive bacterial C-prenyltransferase.

Nat Chem Biol 2017 04 6;13(4):366-368. Epub 2017 Feb 6.

Center for Pharmaceutical Research and Innovation (CPRI), University of Kentucky, Lexington, Kentucky, USA.

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http://dx.doi.org/10.1038/nchembio.2285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362326PMC
April 2017

A scalable lysyl hydroxylase 2 expression system and luciferase-based enzymatic activity assay.

Arch Biochem Biophys 2017 03 20;618:45-51. Epub 2017 Feb 20.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2017.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619865PMC
March 2017

Mechanism of Human Apohemoglobin Unfolding.

Biochemistry 2017 03 2;56(10):1444-1459. Epub 2017 Mar 2.

Department of BioSciences and ‡Department of Chemistry, Rice University , Houston, Texas 77251, United States.

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http://dx.doi.org/10.1021/acs.biochem.6b01235DOI Listing
March 2017

OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.

Chembiochem 2017 02 9;18(4):363-367. Epub 2017 Jan 9.

Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY, 40536, USA.

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http://dx.doi.org/10.1002/cbic.201600676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355705PMC
February 2017

Reader domain specificity and lysine demethylase-4 family function.

Nat Commun 2016 11 14;7:13387. Epub 2016 Nov 14.

Wisconsin Institute for Discovery, Morgridge Institute for Research, University of Wisconsin-Madison, Madison, Wisconsin 53715, USA.

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http://dx.doi.org/10.1038/ncomms13387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114558PMC
November 2016

Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways.

ACS Chem Biol 2016 09 14;11(9):2484-91. Epub 2016 Jul 14.

Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky , 789 South Limestone Street, Lexington, Kentucky 40536-0596, United States.

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http://dx.doi.org/10.1021/acschembio.6b00348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026608PMC
September 2016

Improving the efficiency of molecular replacement by utilizing a new iterative transform phasing algorithm.

Acta Crystallogr A Found Adv 2016 09 15;72(Pt 5):539-47. Epub 2016 Jul 15.

Department of Physics and Texas Center for Superconductivity, University of Houston, Houston, Texas 77204, USA.

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http://scripts.iucr.org/cgi-bin/paper?S2053273316010731
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http://dx.doi.org/10.1107/S2053273316010731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006650PMC
September 2016

Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis.

Struct Dyn 2016 Jan 18;3(1):012004. Epub 2016 Feb 18.

Center for Pharmaceutical Research and Innovation, Pharmaceutical Sciences, University of Kentucky College of Pharmacy , Lexington, Kentucky 40536-0596, USA.

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http://dx.doi.org/10.1063/1.4941368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760980PMC
January 2016

Preface to Special Topic on Protein Dynamics: Beyond Static Snapshots in Structural Biology.

Struct Dyn 2016 Jan 26;3(1):011901. Epub 2016 Feb 26.

Center for Theoretical Biological Physics and Department of Physics, Rice University , Houston, Texas 77005, USA.

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http://dx.doi.org/10.1063/1.4942424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803324PMC
January 2016

Structural Characterization of CalS8, a TDP-α-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis.

J Biol Chem 2015 Oct 3;290(43):26249-58. Epub 2015 Aug 3.

the Department of BioSciences, Department of Chemistry, Rice University, Houston, Texas 77005 the Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, and

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http://dx.doi.org/10.1074/jbc.M115.673459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646273PMC
October 2015

Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.

Proc Natl Acad Sci U S A 2015 Oct 29;112(41):12693-8. Epub 2015 Sep 29.

Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458; Natural Products Library Initiative at The Scripps Research Institute, The Scripps Research Institute, Jupiter, FL 33458

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http://dx.doi.org/10.1073/pnas.1515460112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611616PMC
October 2015

Crystal structure of the protein At3g01520, a eukaryotic universal stress protein-like protein from Arabidopsis thaliana in complex with AMP.

Proteins 2015 07 14;83(7):1368-73. Epub 2015 May 14.

Department of Biochemistry, Center for Eukaryotic Structural Genomics, University of Wisconsin-Madison, Madison, Wisconsin, 53706.

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http://dx.doi.org/10.1002/prot.24821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624624PMC
July 2015

Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway.

PLoS One 2014 30;9(10):e111142. Epub 2014 Oct 30.

Department of Biochemistry, Center for Eukaryotic Structural Genomics, University of Wisconsin Madison, Madison, Wisconsin, United States of America; Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111142PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214742PMC
June 2015

Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases.

Proteins 2014 Oct 28;82(10):2631-42. Epub 2014 Jun 28.

Department of Agricultural Biotechnology, Seoul National University, Seoul, 151-921, Korea.

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http://dx.doi.org/10.1002/prot.24627DOI Listing
October 2014

Structure of RNA 3'-phosphate cyclase bound to substrate RNA.

RNA 2014 Oct 26;20(10):1560-6. Epub 2014 Aug 26.

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA

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http://dx.doi.org/10.1261/rna.045823.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174438PMC
October 2014

An integrated approach for thermal stabilization of a mesophilic adenylate kinase.

Proteins 2014 Sep 24;82(9):1947-59. Epub 2014 Mar 24.

Department of Agricultural Biotechnology, Seoul National University, Seoul, 151-921, Korea.

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http://dx.doi.org/10.1002/prot.24549DOI Listing
September 2014

Structure and substrate specificity of a eukaryotic fucosidase from Fusarium graminearum.

J Biol Chem 2014 Sep 1;289(37):25624-38. Epub 2014 Aug 1.

From Rice University, Houston Texas 77005, Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin 53706,

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http://dx.doi.org/10.1074/jbc.M114.583286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162167PMC
September 2014

Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.

J Mol Biol 2014 Aug 15;426(17):3041-56. Epub 2014 Jun 15.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2014.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219644PMC
August 2014

Evolution of substrate specificity in bacterial AA10 lytic polysaccharide monooxygenases.

Biotechnol Biofuels 2014 6;7:109. Epub 2014 Aug 6.

Department of Energy, Great Lakes Bioenergy Research Center, Madison, 1552 University Avenue, Madison, WI 53726, USA ; Department of Biochemistry, University of Wisconsin-Madison, Biochemistry Addition, 433 Babcock Dr., Madison, WI 53706, USA.

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http://dx.doi.org/10.1186/1754-6834-7-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144037PMC
August 2014

Using a commodity high-definition television for collaborative structural biology.

J Appl Crystallogr 2014 Jun 29;47(Pt 3):1153-1157. Epub 2014 May 29.

Department of Biochemistry and Cell Biology, Rice University, 6100 Main Street, Houston, Texas 77005, USA.

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http://scripts.iucr.org/cgi-bin/paper?S160057671400939X
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http://dx.doi.org/10.1107/S160057671400939XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038803PMC
June 2014

A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation.

Nucleic Acids Res 2014 Apr 16;42(6):3931-42. Epub 2014 Jan 16.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA, Department of Biochemistry and Cell Biology and Department of Chemistry, Rice University, Houston, TX 77005, USA and Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1093/nar/gkt1375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973293PMC
April 2014

Structure, dynamics, and specificity of endoglucanase D from Clostridium cellulovorans.

J Mol Biol 2013 Nov 8;425(22):4267-85. Epub 2013 Jun 8.

Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA; Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.jmb.2013.05.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039632PMC
November 2013

Crystal structure of the protein from Arabidopsis thaliana gene At5g06450, a putative DnaQ-like exonuclease domain-containing protein with homohexameric assembly.

Proteins 2013 Sep 17;81(9):1669-1675. Epub 2013 Jun 17.

Center for Eukaryotic Structural Genomics, Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1002/prot.24315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435538PMC
September 2013

Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis.

Proteins 2013 Jul 20;81(7):1277-82. Epub 2013 Apr 20.

Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA.

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http://dx.doi.org/10.1002/prot.24289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896073PMC
July 2013

Structures of the noncanonical RNA ligase RtcB reveal the mechanism of histidine guanylylation.

Biochemistry 2013 Apr 5;52(15):2518-25. Epub 2013 Apr 5.

Department of Biochemistry, University of Wisconsin, Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/bi4002375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670941PMC
April 2013

Structure of the bifunctional acyltransferase/decarboxylase LnmK from the leinamycin biosynthetic pathway revealing novel activity for a double-hot-dog fold.

Biochemistry 2013 Feb 24;52(5):902-11. Epub 2013 Jan 24.

Department of Chemistry, Scripps Research Institute, The Scripps Research Institute, Jupiter, Florida 33485, United States.

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http://pubs.acs.org/doi/10.1021/bi301652y
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http://dx.doi.org/10.1021/bi301652yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567400PMC
February 2013

A photo-labile thioether linkage to phycoviolobilin provides the foundation for the blue/green photocycles in DXCF-cyanobacteriochromes.

Structure 2013 Jan 6;21(1):88-97. Epub 2012 Dec 6.

Department of Genetics, 425-G Henry Mall, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09692126120041
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http://dx.doi.org/10.1016/j.str.2012.11.001DOI Listing
January 2013

Local functional descriptors for surface comparison based binding prediction.

BMC Bioinformatics 2012 Nov 24;13:314. Epub 2012 Nov 24.

Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1186/1471-2105-13-314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585919PMC
November 2012

The structural biology of enzymes involved in natural product glycosylation.

Nat Prod Rep 2012 Oct 12;29(10):1201-37. Epub 2012 Jun 12.

Laboratory for Biosynthetic Chemistry, Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53705, USA.

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http://xlink.rsc.org/?DOI=c2np20039b
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627186PMC
http://dx.doi.org/10.1039/c2np20039bDOI Listing
October 2012

Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.

Proteins 2012 Aug 7;80(8):2105-2109. Epub 2012 Jun 7.

Department of Biochemistry, Center for Eukaryotic Structural Genomics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1002/prot.24101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226431PMC
August 2012

Structural characterization of human Uch37.

Proteins 2012 Feb 26;80(2):649-54. Epub 2011 Sep 26.

Department of Biochemistry, Center for Eukaryotic Structural Genomics, University of Wisconsin-Madison, Madison Wisconsin 53706-1544.

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http://dx.doi.org/10.1002/prot.23147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251636PMC
February 2012

Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase.

Biochemistry 2012 Feb 2;51(6):1101-13. Epub 2012 Feb 2.

Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544, United States.

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http://dx.doi.org/10.1021/bi2018333DOI Listing
February 2012

Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation.

Curr Opin Biotechnol 2011 Dec 16;22(6):800-8. Epub 2011 May 16.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.copbio.2011.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163058PMC
December 2011

Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A(1).

Proteins 2011 Nov 13;79(11):3236-41. Epub 2011 Sep 13.

Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1002/prot.23153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192245PMC
November 2011

Structure of cellobiose phosphorylase from Clostridium thermocellum in complex with phosphate.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 Nov 25;67(Pt 11):1345-9. Epub 2011 Oct 25.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1107/S1744309111032660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212448PMC
November 2011

Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.

Proc Natl Acad Sci U S A 2011 Oct 10;108(43):17649-54. Epub 2011 Oct 10.

Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA.

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http://dx.doi.org/10.1073/pnas.1108484108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203770PMC
October 2011

Structural characterization of the mitomycin 7-O-methyltransferase.

Proteins 2011 Jul 2;79(7):2181-8. Epub 2011 May 2.

Division of Pharmaceutical Sciences, Wisconsin Center for Natural Product Research, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1002/prot.23040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115387PMC
July 2011

Restructuring the crystalline cellulose hydrogen bond network enhances its depolymerization rate.

J Am Chem Soc 2011 Jul 5;133(29):11163-74. Epub 2011 Jul 5.

Biomass Conversion Research Laboratory, Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan 48824, USA.

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http://dx.doi.org/10.1021/ja2011115DOI Listing
July 2011

Interconversion of functional motions between mesophilic and thermophilic adenylate kinases.

PLoS Comput Biol 2011 Jul 14;7(7):e1002103. Epub 2011 Jul 14.

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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http://dx.plos.org/10.1371/journal.pcbi.1002103
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http://dx.doi.org/10.1371/journal.pcbi.1002103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136430PMC
July 2011

Expanding the nucleotide and sugar 1-phosphate promiscuity of nucleotidyltransferase RmlA via directed evolution.

J Biol Chem 2011 Apr 11;286(15):13235-43. Epub 2011 Feb 11.

Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1074/jbc.M110.206433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075670PMC
April 2011

Structural architecture of Galdieria sulphuraria DCN1L.

Proteins 2011 Apr 18;79(4):1329-36. Epub 2011 Jan 18.

Department of Genetics, Center for Eukaryotic Structural Genomics, University of Wisconsin-Madison, Madison Wisconsin 53706-1544, USA.

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http://dx.doi.org/10.1002/prot.22937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075430PMC
April 2011

Structure of the C-terminal heme-binding domain of THAP domain containing protein 4 from Homo sapiens.

Proteins 2011 Apr 18;79(4):1337-41. Epub 2011 Jan 18.

Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1002/prot.22944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179982PMC
April 2011

Adaptive evolution of threonine deaminase in plant defense against insect herbivores.

Proc Natl Acad Sci U S A 2011 Apr 21;108(14):5897-902. Epub 2011 Mar 21.

Department of Energy-Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1016157108
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http://dx.doi.org/10.1073/pnas.1016157108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078374PMC
April 2011

Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.

Acta Crystallogr D Biol Crystallogr 2011 Mar 15;67(Pt 3):197-203. Epub 2011 Feb 15.

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1107/S090744491100360XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046457PMC
March 2011

Domain view: a web tool for protein domain visualization and analysis.

J Struct Funct Genomics 2010 Dec 14;11(4):241-5. Epub 2010 Oct 14.

Center for Eukaryotic Structural Genomics, Department of Biochemistry, University of Wisconsin at Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1007/s10969-010-9097-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314961PMC
December 2010

Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.

Biochemistry 2010 Nov;49(43):9280-91

Department of Biochemistry and Biophysics, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1021/bi101131fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001272PMC
November 2010

Structural basis for selective activation of ABA receptors.

Nat Struct Mol Biol 2010 Sep 22;17(9):1109-13. Epub 2010 Aug 22.

Department of Biochemistry and Center for Eukaryotic Structural Genomics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

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http://dx.doi.org/10.1038/nsmb.1898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933299PMC
September 2010

GRAPE: GRaphical Abstracted Protein Explorer.

Nucleic Acids Res 2010 Jul 12;38(Web Server issue):W595-601. Epub 2010 May 12.

Department of Computer Sciences, University of Wisconsin-Madison Madison, WI 53715, USA.

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http://dx.doi.org/10.1093/nar/gkq398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896102PMC
July 2010

Many local motions cooperate to produce the adenylate kinase conformational transition.

J Mol Biol 2010 Jul 13;400(3):618-31. Epub 2010 May 13.

Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.jmb.2010.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902635PMC
July 2010

Straight-chain alkyl isocyanides open the distal histidine gate in crystal structures of myoglobin .

Biochemistry 2010 Jun;49(24):4977-86

Department of Biochemistry and Cell Biology and W. M. Keck Center for Computational Biology, Rice University, Houston, Texas 77005, USA.

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http://dx.doi.org/10.1021/bi1001739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074459PMC
June 2010

Crystal structure of an eIF4G-like protein from Danio rerio.

Proteins 2010 May;78(7):1803-6

Center for Eukaryotic Structural Genomics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1002/prot.22703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859309PMC
May 2010

Multi-scale surface descriptors.

IEEE Trans Vis Comput Graph 2009 Nov-Dec;15(6):1201-8

Department of Computer Sciences, University of Wisconsin, Madison, WI, USA.

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http://dx.doi.org/10.1109/TVCG.2009.168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873089PMC
January 2010

Plant science. How plant cells go to sleep for a long, long time.

Science 2009 Dec;326(5958):1356-7

Biotechnology Center and the Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1126/science.1184135DOI Listing
December 2009

X-ray structure of Danio rerio secretagogin: A hexa-EF-hand calcium sensor.

Proteins 2009 Aug;76(2):477-83

Department of Biochemistry, Center for Eukaryotic Structural Genomics, University of Wisconsin-Madison, 53706-1544, USA.

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http://dx.doi.org/10.1002/prot.22362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742686PMC
August 2009

Spherical-harmonic decomposition for molecular recognition in electron-density maps.

Int J Data Min Bioinform 2009 ;3(2):205-27

Department of Computer Sciences, University of Wisconsin, 1210 W. Dayton St., Madison, WI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696052PMC
June 2009

Describing protein conformational ensembles: beyond static snapshots.

F1000 Biol Rep 2009 May 8;1:38. Epub 2009 May 8.

Center for Eukaryotic Structural Genomics, Great Lakes Bioenergy Research Center, Department of Biochemistry 433 Babcock Drive, University of Wisconsin-Madison, Madison, WI 53706 USA.

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http://www.f1000.com/prime/reports/b/1/38
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http://dx.doi.org/10.3410/B1-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924705PMC
May 2009

Application of elastic network models to proteins in the crystalline state.

Biophys J 2009 Jan;96(2):464-75

Program of Computation and Informatics in Biology and Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1016/j.bpj.2008.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716453PMC
January 2009

Structural consequences of effector protein complex formation in a diiron hydroxylase.

Proc Natl Acad Sci U S A 2008 Dec 25;105(49):19194-8. Epub 2008 Nov 25.

Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706-1544, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0807948105
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614738PMC
December 2008

Optimal design of thermally stable proteins.

Bioinformatics 2008 Oct 22;24(20):2339-43. Epub 2008 Aug 22.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1093/bioinformatics/btn450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562006PMC
October 2008