George Murphy

George Murphy

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George Murphy

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Reversal of TET-mediated 5-hmC loss in hypoxic fibroblasts by ascorbic acid.

Lab Invest 2019 Jul 5;99(8):1193-1202. Epub 2019 Mar 5.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41374-019-0235-8DOI Listing
July 2019

Paraneoplastic Hypomyopathic Dermatomyositis Associated With EGFR Exon-20 Insertion NSCLC.

J Thorac Oncol 2019 Jun;14(6):e128-e130

Harvard Medical School, Boston, Massachusetts; Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts; Center for Cutaneous Oncology, Dana Farber Cancer Institute, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.01.026DOI Listing
June 2019

RADIATE - Radial Dysplasia Assessment, Treatment and Aetiology: protocol for the development of a core outcome set using a Delphi survey.

Trials 2019 Jun 10;20(1):339. Epub 2019 Jun 10.

Department of Plastic Surgery, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK.

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http://dx.doi.org/10.1186/s13063-019-3459-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558817PMC
June 2019

Differential distribution of the epigenetic marker 5-hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation.

J Cutan Pathol 2019 May 1;46(5):327-334. Epub 2019 Apr 1.

Department of Pathology, Program in Dermatopathology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/cup.13434DOI Listing
May 2019

Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis.

Blood 2019 May 16;133(22):2455-2459. Epub 2019 Apr 16.

Section of Hematology-Medical Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1182/blood.2018892737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543516PMC
May 2019

Chronic rejection of human face allografts.

Am J Transplant 2019 Apr 10;19(4):1168-1177. Epub 2018 Nov 10.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://doi.wiley.com/10.1111/ajt.15143
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http://dx.doi.org/10.1111/ajt.15143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433509PMC
April 2019

Serial patient-derived orthotopic xenografting of adenoid cystic carcinomas recapitulates stable expression of phenotypic alterations and innervation.

EBioMedicine 2019 Mar 11;41:175-184. Epub 2019 Feb 11.

University of Michigan, Biointerfaces Institute, Ann Arbor, MI, United States; University of Michigan, School of Dentistry, Department of Biologic and Materials Sciences, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442226PMC
March 2019

Sox10 Regulates Plasticity of Epithelial Progenitors toward Secretory Units of Exocrine Glands.

Stem Cell Reports 2019 Feb 31;12(2):366-380. Epub 2019 Jan 31.

University of Michigan, Biointerfaces Institute, 2800 Plymouth Road, Ann Arbor, MI, USA; University of Michigan, School of Dentistry, Department of Biologic and Materials Sciences, 2800 Plymouth Road, Ann Arbor, MI 48109, USA; National Institutes of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373627PMC
February 2019

Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells.

Stem Cells 2018 07 1;36(7):1004-1019. Epub 2018 Apr 1.

Section of Hematology and Oncology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/stem.2822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099224PMC
July 2018

A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression.

Blood Cells Mol Dis 2018 03 29;69:1-9. Epub 2017 Nov 29.

Department of Medicine, Section of Hematology-Oncology, Boston University School of Medicine, Boston, MA 02118, USA; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783741PMC
March 2018

Biological significance of 5-hydroxymethylcytosine in oral epithelial dysplasia and oral squamous cell carcinoma.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Jan 16;125(1):59-73.e2. Epub 2017 Jun 16.

Department of Oral Medicine and Dentistry, Brigham and Women's Hospital, Harvard School of Dental Medicine, Boston, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22124403173084
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http://dx.doi.org/10.1016/j.oooo.2017.06.006DOI Listing
January 2018

Correction of "Wrist" Deformity in Radial Dysplasia: A Systematic Review and Meta-Analysis.

J Bone Joint Surg Am 2017 Dec;99(24):2120-2126

The Portland Hospital for Women and Children, London, United Kingdom.

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http://dx.doi.org/10.2106/JBJS.17.00164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805276PMC
December 2017

Does negative-pressure wound therapy influence subjacent bacterial growth? A systematic review.

J Plast Reconstr Aesthet Surg 2017 Aug 22;70(8):1028-1037. Epub 2017 May 22.

Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bjps.2017.05.027DOI Listing
August 2017

Dioxins and related environmental contaminants increase TDP-43 levels.

Mol Neurodegener 2017 05 5;12(1):35. Epub 2017 May 5.

Department of Pharmacology, Boston University School of Medicine, 72 East Concord St., R614, Boston, MA, 02118-2526, USA.

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http://dx.doi.org/10.1186/s13024-017-0177-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420162PMC
May 2017

A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells.

Stem Cell Reports 2017 04 19;8(4):1076-1085. Epub 2017 Jan 19.

Department of Medicine, Center for Regenerative Medicine (CReM), Boston University School of Medicine, 670 Albany Street, 2nd Floor, Boston, MA 02118, USA; Section of Hematology-Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390092PMC
April 2017

Targeting melanoma with front-line therapy does not abrogate Nodal-expressing tumor cells.

Lab Invest 2017 02 24;97(2):176-186. Epub 2016 Oct 24.

Melanoma Institute Australia and Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1038/labinvest.2016.107DOI Listing
February 2017

Gene expression profiling of anti-CTLA4-treated metastatic melanoma in patients with treatment-induced autoimmunity.

Lab Invest 2017 02 5;97(2):207-216. Epub 2016 Dec 5.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/labinvest.2016.126DOI Listing
February 2017

Tbx5 Buffers Inherent Left/Right Asymmetry Ensuring Symmetric Forelimb Formation.

PLoS Genet 2016 Dec 19;12(12):e1006521. Epub 2016 Dec 19.

Division of Developmental Biology, MRC-National Institute for Medical Research, Mill Hill, London, England.

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http://dx.doi.org/10.1371/journal.pgen.1006521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215935PMC
December 2016

Histopathologic spectrum of hypersensitivity reactions associated with anti-CD52 therapy (alemtuzumab).

J Cutan Pathol 2016 Nov 9;43(11):989-993. Epub 2016 Sep 9.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/cup.12800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507594PMC
November 2016

Decreased tumor-infiltrating lymphocytes in nodular melanomas compared with matched superficial spreading melanomas.

Melanoma Res 2016 10;26(5):524-7

aHarvard Medical School bMihm Cutaneous Pathology Consultative Service cProgram in Dermatopathology, Department of Pathology dDepartment of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts eDepartment of Biostatistics, Tulane University, New Orleans, Louisiana, USA.

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http://dx.doi.org/10.1097/CMR.0000000000000253DOI Listing
October 2016

Multisystemic Disease Modeling of Liver-Derived Protein Folding Disorders Using Induced Pluripotent Stem Cells (iPSCs).

Methods Mol Biol 2016 ;1353:261-70

School of Medicine and the Center for Regenerative Medicine (CReM), Boston University, Boston, MA, USA.

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http://dx.doi.org/10.1007/7651_2014_194DOI Listing
August 2016

Failure of antibiotics in cellulitis trials: a systematic review and meta-analysis.

Am J Emerg Med 2016 Aug 26;34(8):1645-52. Epub 2016 May 26.

Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07356757163019
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http://dx.doi.org/10.1016/j.ajem.2016.05.064DOI Listing
August 2016

TET2 Negatively Regulates Nestin Expression in Human Melanoma.

Am J Pathol 2016 06 18;186(6):1427-34. Epub 2016 Apr 18.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901139PMC
June 2016

Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57.

Exp Hematol 2016 May 10;44(5):422-433.e1. Epub 2016 Feb 10.

Section of Gastroenterology, Department of Medicine, Boston University School of Medicine, Boston, MA; Center for Regenerative Medicine (CReM), Boston University and Boston Medical Center, Boston, MA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X160003
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http://dx.doi.org/10.1016/j.exphem.2016.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555112PMC
May 2016

Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development.

Stem Cells Int 2016 11;2016:2574152. Epub 2016 Apr 11.

Section of Hematology and Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; Center for Regenerative Medicine (CReM), Boston University and Boston Medical Center, Boston, MA 02118, USA.

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http://dx.doi.org/10.1155/2016/2574152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842384PMC
May 2016

Face Transplantation in a Highly Sensitized Recipient.

Mil Med 2016 05;181(5 Suppl):221-6

Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.7205/MILMED-D-15-00136DOI Listing
May 2016

Diagnostic Immunohistochemistry in Cutaneous Neoplasia: An Update.

Dermatopathology (Basel) 2015 Jan-Mar;2(1):15-42. Epub 2015 Apr 8.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000377698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816435PMC
April 2016

ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth.

J Invest Dermatol 2016 Apr 29;136(4):838-846. Epub 2016 Jan 29.

Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821468PMC
April 2016

The Genetic Evolution of Melanoma.

N Engl J Med 2016 03;374(10):994-5

Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1056/NEJMc1515834DOI Listing
March 2016

The Efficacy and Safety of Tranexamic Acid in Cranio-Maxillofacial and Plastic Surgery.

J Craniofac Surg 2016 Mar;27(2):374-9

*St Hugh's College, University of Oxford†Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford‡Department of Plastic and Reconstructive Surgery, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, UK.

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http://dx.doi.org/10.1097/SCS.0000000000002250DOI Listing
March 2016

Cutaneous Squamous Cell Carcinomas of the Lower Extremities Show Distinct Clinical and Pathologic Features.

Int J Surg Pathol 2016 Feb 10;24(1):29-36. Epub 2015 Aug 10.

Massachusetts General Hospital, Boston, MA, USA

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http://dx.doi.org/10.1177/1066896915599058DOI Listing
February 2016

Chloroplast lipid transfer processes in Chlamydomonas reinhardtii involving a TRIGALACTOSYLDIACYLGLYCEROL 2 (TGD2) orthologue.

Plant J 2015 Dec;84(5):1005-20

MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, Michigan, 48824, USA.

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http://dx.doi.org/10.1111/tpj.13060DOI Listing
December 2015

Decrease of 5-hydroxymethylcytosine in rat liver with subchronic exposure to genotoxic carcinogens riddelliine and aristolochic acid.

Mol Carcinog 2015 Nov 23;54(11):1503-7. Epub 2014 Aug 23.

Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas.

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http://dx.doi.org/10.1002/mc.22201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832966PMC
November 2015

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma.

Oncotarget 2015 Nov;6(35):37995-8004

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.18632/oncotarget.6062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741979PMC
November 2015

Epigenetic markers in melanoma.

Melanoma Manag 2015 Nov 24;2(4):367-382. Epub 2015 Nov 24.

Program in Dermatopathology, Department of Pathology, Brigham & Women's Hospital, Harvard Medical School, 221 Longwood Ave. EBRC 401, Boston, MA 02115, USA.

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http://dx.doi.org/10.2217/mmt.15.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094672PMC
November 2015

Repigmentation of extensive inflammatory vitiligo with raised borders using early and aggressive treatment.

Dermatology 2015 18;230(1):11-5. Epub 2014 Nov 18.

Harvard Medical School, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000366197DOI Listing
September 2015

ABCB5 Identifies Immunoregulatory Dermal Cells.

Cell Rep 2015 Sep 28;12(10):1564-74. Epub 2015 Aug 28.

Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115, USA; Transplantation Research Center, Boston Children's Hospital and Brigham and Women's Hospital, Boston, MA 02115, USA; School of Medical Sciences, Edith Cowan University, Joondalup, WA 6027, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565759PMC
September 2015

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

Cell 2015 Sep;162(6):1242-56

Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.08.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700833PMC
September 2015

Impact of the 2009 AJCC staging guidelines for melanoma on the number of mitotic figures reported by dermatopathologists at one institution.

J Cutan Pathol 2015 Aug 26;42(8):536-41. Epub 2015 May 26.

Division of Dermatopathology, Department of Pathology, Brigham and Women's, Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/cup.12517DOI Listing
August 2015

Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential.

J Invest Dermatol 2015 Jul 10;135(7):1849-1862. Epub 2015 Mar 10.

Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466041PMC
July 2015

Targeting nodal in conjunction with dacarbazine induces synergistic anticancer effects in metastatic melanoma.

Mol Cancer Res 2015 Apr 12;13(4):670-80. Epub 2015 Mar 12.

Program in Cancer Biology and Epigenomics, Stanley Manne Children's Research Institute at Ann and Robert H. Lurie Children's Hospital of Chicago, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398626PMC
April 2015

Oxygen reduces tourniquet-associated pain: a double-blind, randomized, controlled trial for application in hand surgery.

Plast Reconstr Surg 2015 Apr;135(4):721e-30e

Oxford and Wiltshire, United Kingdom From the Department of Plastic and Reconstructive Surgery, Oxford University Hospitals NHS Trust; and the Department of Plastic and Reconstructive Surgery, Salisbury District Hospital, Salisbury NHS Foundation Trust.

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https://insights.ovid.com/crossref?an=00006534-201504000-000
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http://dx.doi.org/10.1097/PRS.0000000000001028DOI Listing
April 2015

5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies.

Mod Pathol 2015 Feb 1;28(2):218-29. Epub 2014 Aug 1.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2014.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312506PMC
February 2015

Hydrostatic pressure-driven three-dimensional cartilage induction using human adipose-derived stem cells and collagen gels.

Tissue Eng Part A 2015 Jan 19;21(1-2):257-66. Epub 2014 Sep 19.

1 Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital , Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1089/ten.TEA.2013.0525DOI Listing
January 2015

Utility of sentinel flaps in assessing facial allograft rejection.

Plast Reconstr Surg 2015 Jan;135(1):250-8

Boston, Mass.; and Bochum and Ludwigshafen, Germany From the Department of Surgery, Division of Plastic Surgery, the Division of Dermatopathology, Department of Pathology, the Division of Infectious Diseases, and the Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School; the Department of Plastic Surgery, Burn Center, Sarcoma Reference Center, BG University Hospital Bergmannsheil, Ruhr University Bochum; and the Department of Hand, Plastic, and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen, University of Heidelberg.

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http://dx.doi.org/10.1097/PRS.0000000000000797DOI Listing
January 2015

Acute rejection in vascularized composite allotransplantation.

Curr Opin Organ Transplant 2014 Dec;19(6):531-44

aDivision of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA bDepartment of Hand, Plastic and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen; University of Heidelberg Ludwigshafen, Germany cDivision of Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA dDepartment of Plastic Surgery, BG University Hospital Bergmannsheil, Ruhr-University, Bochum, Bochum, Germany eThe Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston fInstitute for Medical Engineering and Science, Cambridge gCardiovascular Division, Brigham and Women's Hospital hDepartment of Dermatology, Brigham and Women's Hospital iRenal Division, Schuster Family Transplantation Research Center, Brigham and Women's Hospital and Children's Hospital Boston jDivision of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MOT.0000000000000140DOI Listing
December 2014

Hand transplants and the mandate for tolerance.

Curr Opin Organ Transplant 2014 Dec;19(6):545-51

aDepartment of Medicine, Harvard Medical School, Transplant Institute, Beth Israel Deaconess Medical Center bDivision of Plastic Surgery, Department of Surgery cDivision of Dermatopathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MOT.0000000000000138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352932PMC
December 2014

Airway recovery after face transplantation.

Plast Reconstr Surg 2014 Dec;134(6):946e-54e

Boston, Mass.; and Ludwigshafen, Germany From the Department of Surgery, Divisions of Plastic Surgery and Otolaryngology, and the Division of Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School; the Department of Plastic Surgery, BG University Hospital Bergmannsheil, Ruhr-University, Bochum, Germany; the Department of Hand-, Plastic and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen, University of Heidelberg; and the Dana Farber Cancer Institute.

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http://dx.doi.org/10.1097/PRS.0000000000000752DOI Listing
December 2014

Merkel cell carcinoma expresses vasculogenic mimicry: demonstration in patients and experimental manipulation in xenografts.

Lab Invest 2014 Oct 11;94(10):1092-102. Epub 2014 Aug 11.

1] Harvard Medical School, Boston, MA, USA [2] Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/labinvest.2014.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236190PMC
October 2014

Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells.

Immunity 2014 Oct 9;41(4):579-91. Epub 2014 Oct 9.

Kimmel Center for Biology and Medicine at the Skirball Institute, New York, NY 10016, USA; Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237219PMC
October 2014

Evaluation of stromal HGF immunoreactivity as a biomarker for melanoma response to RAF inhibitors.

Mod Pathol 2014 Sep 17;27(9):1193-202. Epub 2014 Jan 17.

1] Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA [2] Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2013.226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107197PMC
September 2014

Clinical characteristics of reticular pseudodrusen in the fellow eye of patients with unilateral neovascular age-related macular degeneration.

Ophthalmology 2014 Sep 21;121(9):1748-55. Epub 2014 May 21.

Center for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2014.03.015DOI Listing
September 2014

Stem cells, megakaryocytes, and platelets.

Curr Opin Hematol 2014 Sep;21(5):430-7

aSection of Hematology and Oncology, Department of Medicine, Boston University School of Medicine bCenter for Regenerative Medicine, Boston University and Boston Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323081PMC
September 2014

ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit.

Cancer Res 2014 Aug 16;74(15):4196-207. Epub 2014 Jun 16.

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Transplant Research Program, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://cancerres.aacrjournals.org/content/early/2014/07/17/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-0582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119553PMC
August 2014

Melanoma epigenetics: novel mechanisms, markers, and medicines.

Lab Invest 2014 Aug 30;94(8):822-38. Epub 2014 Jun 30.

Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/labinvest.2014.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479581PMC
August 2014

ABCB5 is a limbal stem cell gene required for corneal development and repair.

Nature 2014 Jul 2;511(7509):353-7. Epub 2014 Jul 2.

1] Department of Medicine, VA Boston Healthcare System, Boston, Massachusetts 02130, USA [2] Transplant Research Program, Division of Nephrology, Boston Children's Hospital, Boston, Massachusetts 02115, USA [3] Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts 02138, USA [4] Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [5].

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http://dx.doi.org/10.1038/nature13426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246512PMC
July 2014

Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury.

Mod Pathol 2014 Jun 17;27(6):788-99. Epub 2014 Jan 17.

Division of Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/modpathol2013249
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http://dx.doi.org/10.1038/modpathol.2013.249DOI Listing
June 2014

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity.

Cancer Discov 2014 May 18;4(5):578-91. Epub 2014 Feb 18.

Departments of 1Immunology, 2Computational Biology and Immunology, 3Pediatrics, and 4Medicine and Immunology, Memorial Sloan-Kettering Cancer Center; 5Department of Immunology, Weill-Cornell Medical Center, New York, New York; 6Program in Dermatopathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and 7Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011979PMC
May 2014

A prostaglandin D-synthase-positive mast cell gradient characterizes scalp patterning.

J Cutan Pathol 2014 Apr 20;41(4):364-9. Epub 2014 Jan 20.

Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1111/cup.12286DOI Listing
April 2014

Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions.

J Immunol 2014 Mar 12;192(6):2812-20. Epub 2014 Feb 12.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.4049/jimmunol.1301794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970423PMC
March 2014

ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor.

J Neurosci 2014 Mar;34(12):4167-74

Department of Pharmacology and Experimental Therapeutics and Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, Center for Regenerative Medicine, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, and Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224.

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http://dx.doi.org/10.1523/JNEUROSCI.2350-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960463PMC
March 2014

Evaluation of American Joint Committee on Cancer, International Union Against Cancer, and Brigham and Women's Hospital tumor staging for cutaneous squamous cell carcinoma.

J Clin Oncol 2014 Feb 23;32(4):327-34. Epub 2013 Dec 23.

Pritesh S. Karia, George F. Murphy, Abrar A. Qureshi, and Chrysalyne D. Schmults, Brigham and Women's Hospital, Harvard Medical School; David P. Harrington, Harvard School of Public Health, Boston, MA; and Anokhi Jambusaria-Pahlajani, Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1200/JCO.2012.48.5326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897257PMC
February 2014

The multidrug-resistance transporter ABCB5 is expressed in human placenta.

Int J Gynecol Pathol 2014 Jan;33(1):45-51

Departments of Pathology (E.R.V., C.L., Q.Z., C.P.C., G.F.M Dermatology (S.D.G., M.H.F.) Division of Genetics (N.Y.F.), Brigham and Women's Hospital Harvard Medical School (E.R.V., C.L., Q.Z., S.D.G., M.H.F., N.Y.F., C.P.C., G.F.M.) Transplantation Research Center (M.H.F., N.Y.F.), Children's Hospital, Boston Converge Diagnostic Services (D.W.K.), Peabody Department of Medicine (N.Y.F.), VA Boston Healthcare System, Jamaica Plain, Massachusetts.

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http://dx.doi.org/10.1097/PGP.0b013e31829c677fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909935PMC
January 2014

Melanoma spheroid formation involves laminin-associated vasculogenic mimicry.

Am J Pathol 2014 Jan;184(1):71-8

Division of Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873495PMC
January 2014