George Klee

George Klee

UNVERIFIED PROFILE

Are you George Klee?   Register this Author

Register author
George Klee

George Klee

Publications by authors named "George Klee"

Are you George Klee?   Register this Author

98Publications

1667Reads

28Profile Views

Roles of kallikrein-2 biomarkers (free-hK2 and pro-hK2) for predicting prostate cancer progression-free survival.

J Circ Biomark 2017 Jan-Dec;6:1849454417720151. Epub 2017 Jul 20.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1849454417720151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599013PMC
July 2017

Interleukins 6 and 8 and abdominal fat depots are distinct correlates of lipid moieties in healthy pre- and postmenopausal women.

Endocrine 2016 Dec 22;54(3):671-680. Epub 2016 Jul 22.

Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12020-016-1041-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107333PMC
December 2016

Multiple calibrator measurements improve accuracy and stability estimates of automated assays.

Scand J Clin Lab Invest 2016 19;76(2):177-80. Epub 2016 Jan 19.

a Department of Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN , USA ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/00365513.2015.1126760DOI Listing
November 2016

The cistrome and gene signature of androgen receptor splice variants in castration resistant prostate cancer cells.

J Urol 2015 Feb 14;193(2):690-8. Epub 2014 Aug 14.

Department of Urology, Mayo Clinic, Rochester, Minnesota; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.juro.2014.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411637PMC
February 2015

Evaluation of Beckman Coulter DxI 800 immunoassay system using clinically oriented performance goals.

Clin Biochem 2014 Nov 15;47(16-17):158-63. Epub 2014 Aug 15.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2014.08.005DOI Listing
November 2014

Serum concentrations of prostate-specific antigen measured using immune extraction, trypsin digestion, and tandem mass spectrometry quantification of LSEPAELTDAVK peptide.

Arch Pathol Lab Med 2014 Oct;138(10):1381-6

From the Departments of Health Sciences Research (Dr E. Klee and Mr Bergstralh) and Laboratory Medicine and Pathology (Drs Bondar, Trushin, Singh, and G. Klee and Ms. Goodmanson), Mayo Clinic College of Medicine, Rochester, Minnesota; and the Plasma Proteome Institute, Washington, DC (Dr Anderson).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5858/arpa.2013-0462-OADOI Listing
October 2014

Verifying performance characteristics of quantitative analytical systems: calibration verification, linearity, and analytical measurement range.

Arch Pathol Lab Med 2014 Sep;138(9):1173-81

From the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (Dr Killeen); the Department of Biostatistics (Mr Long, Ms Souers, and Dr Styer) and the Instrumentation Resource Committee (Ms Ventura), College of American Pathologists, Northfield, Illinois; and the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota (Dr Klee).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5858/arpa.2013-0051-CPDOI Listing
September 2014

Immunologic and mass-spectrometric estimates of SHBG concentrations in healthy women.

Metabolism 2014 Jun 21;63(6):783-92. Epub 2014 Mar 21.

Laboratory Medicine and Pathology, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.metabol.2014.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066221PMC
June 2014

Reprint of "Influence of analytical bias and imprecision on the number of false positive results using Guideline-Driven Medical Decision Limits".

Clin Chim Acta 2014 May 18;432:127-34. Epub 2014 Apr 18.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cca.2014.04.002DOI Listing
May 2014

Influence of analytical bias and imprecision on the number of false positive results using Guideline-Driven Medical Decision Limits.

Clin Chim Acta 2014 Mar 18;430:1-8. Epub 2013 Dec 18.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00098981130050
Publisher Site
http://dx.doi.org/10.1016/j.cca.2013.12.014DOI Listing
March 2014

Immunological and mass spectrometric assays of SHBG: consistent and inconsistent metabolic associations in healthy men.

J Clin Endocrinol Metab 2014 Jan 20;99(1):184-93. Epub 2013 Dec 20.

Endocrine Research Unit (J.D.V.), Mayo School of Graduate Medical Education Center for Translational Science Activities, Immunochemical Laboratory (R.B.D.), and Departments of Neurology (S.A.T.) and Laboratory Medicine and Pathology (J.D.V., O.P.B., E.W.K., R.J.S., G.G.K.), Mayo Clinic, Rochester, Minnesota 55905.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2013-2642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879680PMC
January 2014

Empiric validation of simulation models for estimating glucose meter performance criteria for moderate levels of glycemic control.

Diabetes Technol Ther 2013 Dec 13;15(12):996-1003. Epub 2013 Sep 13.

1 Department of Laboratory Medicine and Pathology, Mayo Clinic , Rochester, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/dia.2013.0086DOI Listing
December 2013

Utility of a panel of sera for the alignment of test results in the worldwide multicenter study on reference values.

Clin Chem Lab Med 2013 May;51(5):1007-25

Faculty of Health Sciences, Department of Clinical Laboratory Sciences, Graduate School of Medicine, Yamaguchi University, Minami-Kogushi 1-1-1, Ube 755-8505, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/cclm-2013-0248DOI Listing
May 2013

Protocol and standard operating procedures for common use in a worldwide multicenter study on reference values.

Clin Chem Lab Med 2013 May;51(5):1027-40

Department of Biochemistry and Clinical Biochemistry, Uludag University Medical School of Medicine, Bursa, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/cclm-2013-0249DOI Listing
May 2013

Associations of candidate biomarkers of vascular disease with the ankle-brachial index and peripheral arterial disease.

Am J Hypertens 2013 Apr 11;26(4):495-502. Epub 2013 Jan 11.

Division of Cardiovascular Diseases and the Gonda Vascular Center, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/ajh/article-lookup/doi/10.1093/ajh/
Publisher Site
http://dx.doi.org/10.1093/ajh/hps073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626040PMC
April 2013

Analytical performance specifications: relating laboratory performance to quality required for intended clinical use.

Clin Lab Med 2013 Mar 20;33(1):55-73. Epub 2012 Dec 20.

Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cll.2012.11.005DOI Listing
March 2013

Application of mathematical models of system uncertainty to evaluate the utility of assay calibration protocols.

Clin Chem Lab Med 2012 Nov;50(11):1945-51

School of Industrial Engineering, Purdue University, West Lafayette, IN, USA.

View Article

Download full-text PDF

Source
https://www.degruyter.com/view/j/cclm.2012.50.issue-11/cclm-
Publisher Site
http://dx.doi.org/10.1515/cclm-2012-0265DOI Listing
November 2012

Multi-center analytical performance evaluation of the Access Hybritech® p2PSA immunoassay.

Clin Chim Acta 2012 Aug 20;413(15-16):1279-83. Epub 2012 Apr 20.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cca.2012.04.015DOI Listing
August 2012

Global methylation profiling for risk prediction of prostate cancer.

Clin Cancer Res 2012 May;18(10):2882-95

Department of Urology and Laboratory Medicine and Pathology, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-2090DOI Listing
May 2012

Hereditary hyperferritinemia-cataract syndrome in two large multigenerational American families.

J AAPOS 2011 Aug;15(4):356-61

College of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaapos.2011.03.020DOI Listing
August 2011

Biologic variation of a novel cardiac troponin I assay.

Clin Chem 2011 Jul 25;57(7):1080-1. Epub 2011 Apr 25.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2011.162545DOI Listing
July 2011

Glucose meter performance criteria for tight glycemic control estimated by simulation modeling.

Clin Chem 2010 Jul 28;56(7):1091-7. Epub 2010 May 28.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://www.clinchem.org/cgi/doi/10.1373/clinchem.2010.145367
Publisher Site
http://dx.doi.org/10.1373/clinchem.2010.145367DOI Listing
July 2010

Harmonization and standardization of thyroid function tests.

Authors:
George G Klee

Clin Chem 2010 Jun 8;56(6):879-80. Epub 2010 Apr 8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2010.145540DOI Listing
June 2010

Establishment of outcome-related analytic performance goals.

Authors:
George G Klee

Clin Chem 2010 May 26;56(5):714-22. Epub 2010 Mar 26.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2009.133660DOI Listing
May 2010

Antibody-based protein multiplex platforms: technical and operational challenges.

Clin Chem 2010 Feb 3;56(2):186-93. Epub 2009 Dec 3.

Division of Cardiovascular Diseases, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2009.127514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901849PMC
February 2010

Effects of analytic variations in creatinine measurements on the classification of renal disease using estimated glomerular filtration rate (eGFR).

Clin Chem Lab Med 2007 ;45(6):737-41

Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/CCLM.2007.168DOI Listing
January 2008

Association of plasma resistin with glomerular filtration rate and albuminuria in hypertensive adults.

Hypertension 2007 Oct 4;50(4):708-14. Epub 2007 Sep 4.

Division of Cardiovascular Diseases, Mayo Clinic, 200 First St Southwest, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.095257DOI Listing
October 2007

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men.

Diabetes Care 2007 Aug 11;30(8):1972-8. Epub 2007 May 11.

Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/dc07-0359DOI Listing
August 2007

LC-MS/MS quantification of Zn-alpha2 glycoprotein: a potential serum biomarker for prostate cancer.

Clin Chem 2007 Apr 22;53(4):673-8. Epub 2007 Feb 22.

Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2006.079681DOI Listing
April 2007

Bioinformatics methods for prioritizing serum biomarker candidates.

Clin Chem 2006 Nov;52(11):2162-4

Mayo Clinic, 315 Stabile Building, Rochester, MN 55904, USA.

View Article

Download full-text PDF

Source
November 2006

B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema.

Crit Care Med 2006 Jul;34(7):1941-6

Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.CCM.0000220492.15645.47DOI Listing
July 2006

Comparison of pooled fresh frozen serum to proficiency testing material in College of American Pathologists surveys: cortisol and immunoglobulin E.

Arch Pathol Lab Med 2005 Mar;129(3):305-9

Department of Pathology, Massachusetts General Hospital and Harvard Partners Center for Genetics and Genomics, Boston, Mass, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1043/1543-2165(2005)129<305:COPFFS>2.0.CO;2DOI Listing
March 2005

Clinical interpretation of reference intervals and reference limits. A plea for assay harmonization.

Authors:
George G Klee

Clin Chem Lab Med 2004 ;42(7):752-7

Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/CCLM.2004.127DOI Listing
February 2005

Absolute quantification of the model biomarker prostate-specific antigen in serum by LC-Ms/MS using protein cleavage and isotope dilution mass spectrometry.

J Proteome Res 2004 May-Jun;3(3):644-52

W.M. Keck FT-ICR Mass Spectrometry Laboratory, Mayo Proteomics Research Center, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

View Article

Download full-text PDF

Source
December 2004

Serum sex hormones and measures of benign prostatic hyperplasia.

Prostate 2004 Oct;61(2):124-31

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.20080DOI Listing
October 2004

MUC1 gene-derived glycoprotein assays for monitoring breast cancer (CA 15-3, CA 27.29, BR): are they measuring the same antigen?

Arch Pathol Lab Med 2004 Oct;128(10):1131-5

Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, Rochester, Minn 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1043/1543-2165(2004)128<1131:MGGAFM>2.0.CO;2DOI Listing
October 2004

Sex-specific associations of lipoprotein(a) with presence and quantity of coronary artery calcification in an asymptomatic population.

Med Sci Monit 2004 Sep 20;10(9):CR493-503. Epub 2004 Aug 20.

Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 47104-3028, USA.

View Article

Download full-text PDF

Source
September 2004

How sensitive is a prostate-specific antigen measurement? How sensitive does it need to be?

Arch Pathol Lab Med 2004 Mar;128(3):341-3

Department of Pathology, Stony Brook University, Stony Brook, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1043/1543-2165(2004)128<341:HSIAPA>2.0.CO;2DOI Listing
March 2004

Interferences in hormone immunoassays.

Authors:
George G Klee

Clin Lab Med 2004 Mar;24(1):1-18

Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cll.2004.01.003DOI Listing
March 2004

Considerations on development, validation, application, and quality control of immuno(metric) biomarker assays in clinical cancer research: an EORTC-NCI working group report.

Int J Oncol 2003 Dec;23(6):1715-26

Department of Chemical Endocrinology, University Medical Center Nijmegen, NL-6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
December 2003

Cytokine production patterns and antibody response to measles vaccine.

Vaccine 2003 Sep;21(25-26):3946-53

Department of Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0264-410x(03)00272-xDOI Listing
September 2003

Insulin-like growth factor I, insulin-like growth factor binding protein 3, and urologic measures of benign prostatic hyperplasia.

Am J Epidemiol 2003 May;157(9):784-91

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/aje/kwf054DOI Listing
May 2003

Factors influencing clinical decisions to initiate thyroxine therapy for patients with mildly increased serum thyrotropin (5.1-10.0 mIU/L).

Mayo Clin Proc 2003 May;78(5):554-60

Division of Endocrinology, Diabetes, Metabolism, Nutrition and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S002561961161922
Publisher Site
http://dx.doi.org/10.4065/78.5.554DOI Listing
May 2003

A longitudinal replicate study of immunosuppressive drugs: a College of American Pathologists study.

Arch Pathol Lab Med 2003 Mar;127(3):283-8

Department of Pathology, University of Miami School of Medicine, Miami, FL, USA. bsteele;camed.miami.edu

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1043/0003-9985(2003)127<0283:ALRSOI>2.0.CO;2DOI Listing
March 2003

Lack of association between plasma homocysteine and angiographic coronary artery disease in the era of fortification of cereal grain flour with folic acid.

Atherosclerosis 2002 Dec;165(2):375-81

Division of Cardiovascular Diseases W16, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0021-9150(02)00303-9DOI Listing
December 2002

Extrinsic neural regulation of antroduodenal motor activity in preterm infants.

Dig Dis Sci 2002 Dec;47(12):2657-63

Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1023/a:1021084517391DOI Listing
December 2002

Cancer antigen 125 in patients with chronic liver disease.

Mayo Clin Proc 2002 Jun;77(6):538-41

Division of Gastroenterology and Hepatology and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4065/77.6.538DOI Listing
June 2002

Symptomatic hyperthyroidism in a patient taking the dietary supplement tiratricol.

Mayo Clin Proc 2002 Jun;77(6):587-90

Division of Area General Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4065/77.6.587DOI Listing
June 2002