George J Weiner

George J Weiner

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George J Weiner

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Diagnosis-to-Treatment Interval Is an Important Clinical Factor in Newly Diagnosed Diffuse Large B-Cell Lymphoma and Has Implication for Bias in Clinical Trials.

J Clin Oncol 2018 06 19;36(16):1603-1610. Epub 2018 Apr 19.

Matthew J. Maurer, Thomas M. Habermann, Carrie A. Thompson, Cristine Allmer, Patrick B. Johnston, Ivana N. Micallef, David J. Inwards, William R. Macon, Andrew L. Feldman, Susan L. Slager, Stephen M. Ansell, James R. Cerhan, Thomas E. Witzig, and Grzegorz S. Nowakowski, Mayo Clinic, Rochester, MN; Hervé Ghesquières and Gilles A. Salles, Université Claude Bernard, Lyon; Jean-Philippe Jais, Richard Delarue, Thierry J. Molina, Hopital Necker, Paris; Corinne Haioun, Groupe Hospitalier Mondor, Créteil; Frederic Peyrade, Centre Antoine Lacassagne, Nice; Olivier Fitoussi, Polyclinique Bordeaux Nord-Aquitaine, Bordeaux; Hervé Tilly, Centre de lutte Contre le Cancer Henri Becquerel, Rouen, France; Brian K. Link, Umar Farooq, Sergei Syrbu, and George J. Weiner, University of Iowa, Iowa City, IA; and Nicolas Ketterer, Clinique Bois-Cerf, Lausanne, Switzerland.

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http://dx.doi.org/10.1200/JCO.2017.76.5198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978469PMC
June 2018

Complement-Regulatory Proteins CFHR1 and CFHR3 and Patient Response to Anti-CD20 Monoclonal Antibody Therapy.

Clin Cancer Res 2017 Feb 15;23(4):954-961. Epub 2016 Aug 15.

Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311060PMC
February 2017

Anti-Lymphoma Monoclonal Antibodies: Making Better Antibodies and Making Antibodies Better.

Authors:
George J Weiner

Trans Am Clin Climatol Assoc 2015 ;126:87-92

Iowa City, Iowa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530715PMC
June 2016

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia.

Authors:
Sonja I Berndt Nicola J Camp Christine F Skibola Joseph Vijai Zhaoming Wang Jian Gu Alexandra Nieters Rachel S Kelly Karin E Smedby Alain Monnereau Wendy Cozen Angela Cox Sophia S Wang Qing Lan Lauren R Teras Moara Machado Meredith Yeager Angela R Brooks-Wilson Patricia Hartge Mark P Purdue Brenda M Birmann Claire M Vajdic Pierluigi Cocco Yawei Zhang Graham G Giles Anne Zeleniuch-Jacquotte Charles Lawrence Rebecca Montalvan Laurie Burdett Amy Hutchinson Yuanqing Ye Timothy G Call Tait D Shanafelt Anne J Novak Neil E Kay Mark Liebow Julie M Cunningham Cristine Allmer Henrik Hjalgrim Hans-Olov Adami Mads Melbye Bengt Glimelius Ellen T Chang Martha Glenn Karen Curtin Lisa A Cannon-Albright W Ryan Diver Brian K Link George J Weiner Lucia Conde Paige M Bracci Jacques Riby Donna K Arnett Degui Zhi Justin M Leach Elizabeth A Holly Rebecca D Jackson Lesley F Tinker Yolanda Benavente Núria Sala Delphine Casabonne Nikolaus Becker Paolo Boffetta Paul Brennan Lenka Foretova Marc Maynadie James McKay Anthony Staines Kari G Chaffee Sara J Achenbach Celine M Vachon Lynn R Goldin Sara S Strom Jose F Leis J Brice Weinberg Neil E Caporaso Aaron D Norman Anneclaire J De Roos Lindsay M Morton Richard K Severson Elio Riboli Paolo Vineis Rudolph Kaaks Giovanna Masala Elisabete Weiderpass María-Dolores Chirlaque Roel C H Vermeulen Ruth C Travis Melissa C Southey Roger L Milne Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Jacqueline Clavel Tongzhang Zheng Theodore R Holford Danylo J Villano Ann Maria John J Spinelli Randy D Gascoyne Joseph M Connors Kimberly A Bertrand Edward Giovannucci Peter Kraft Anne Kricker Jenny Turner Maria Grazia Ennas Giovanni M Ferri Lucia Miligi Liming Liang Baoshan Ma Jinyan Huang Simon Crouch Ju-Hyun Park Nilanjan Chatterjee Kari E North John A Snowden Josh Wright Joseph F Fraumeni Kenneth Offit Xifeng Wu Silvia de Sanjose James R Cerhan Stephen J Chanock Nathaniel Rothman Susan L Slager

Nat Commun 2016 Mar 9;7:10933. Epub 2016 Mar 9.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1038/ncomms10933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786871PMC
March 2016

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

Authors:
Joshua N Sampson William A Wheeler Meredith Yeager Orestis Panagiotou Zhaoming Wang Sonja I Berndt Qing Lan Christian C Abnet Laufey T Amundadottir Jonine D Figueroa Maria Teresa Landi Lisa Mirabello Sharon A Savage Philip R Taylor Immaculata De Vivo Katherine A McGlynn Mark P Purdue Preetha Rajaraman Hans-Olov Adami Anders Ahlbom Demetrius Albanes Maria Fernanda Amary She-Juan An Ulrika Andersson Gerald Andriole Irene L Andrulis Emanuele Angelucci Stephen M Ansell Cecilia Arici Bruce K Armstrong Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Nikolaus Becker Yolanda Benavente Simone Benhamou Christine Berg David Van Den Berg Leslie Bernstein Kimberly A Bertrand Brenda M Birmann Amanda Black Heiner Boeing Paolo Boffetta Marie-Christine Boutron-Ruault Paige M Bracci Louise Brinton Angela R Brooks-Wilson H Bas Bueno-de-Mesquita Laurie Burdett Julie Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Alfredo Carrato Tania Carreon Angela Carta John K C Chan Ellen T Chang Gee-Chen Chang I-Shou Chang Jiang Chang Jenny Chang-Claude Chien-Jen Chen Chih-Yi Chen Chu Chen Chung-Hsing Chen Constance Chen Hongyan Chen Kexin Chen Kuan-Yu Chen Kun-Chieh Chen Ying Chen Ying-Hsiang Chen Yi-Song Chen Yuh-Min Chen Li-Hsin Chien María-Dolores Chirlaque Jin Eun Choi Yi Young Choi Wong-Ho Chow Charles C Chung Jacqueline Clavel Françoise Clavel-Chapelon Pierluigi Cocco Joanne S Colt Eva Comperat Lucia Conde Joseph M Connors David Conti Victoria K Cortessis Michelle Cotterchio Wendy Cozen Simon Crouch Marta Crous-Bou Olivier Cussenot Faith G Davis Ti Ding W Ryan Diver Miren Dorronsoro Laure Dossus Eric J Duell Maria Grazia Ennas Ralph L Erickson Maria Feychting Adrienne M Flanagan Lenka Foretova Joseph F Fraumeni Neal D Freedman Laura E Beane Freeman Charles Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina García-Closas Randy D Gascoyne Julie Gastier-Foster Mia M Gaudet J Michael Gaziano Carol Giffen Graham G Giles Edward Giovannucci Bengt Glimelius Michael Goggins Nalan Gokgoz Alisa M Goldstein Richard Gorlick Myron Gross Robert Grubb Jian Gu Peng Guan Marc Gunter Huan Guo Thomas M Habermann Christopher A Haiman Dina Halai Goran Hallmans Manal Hassan Claudia Hattinger Qincheng He Xingzhou He Kathy Helzlsouer Brian Henderson Roger Henriksson Henrik Hjalgrim Judith Hoffman-Bolton Chancellor Hohensee Theodore R Holford Elizabeth A Holly Yun-Chul Hong Robert N Hoover Pamela L Horn-Ross G M Monawar Hosain H Dean Hosgood Chin-Fu Hsiao Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang Jose-Maria Huerta Jen-Yu Hung Amy Hutchinson Peter D Inskip Rebecca D Jackson Eric J Jacobs Mazda Jenab Hyo-Sung Jeon Bu-Tian Ji Guangfu Jin Li Jin Christoffer Johansen Alison Johnson Yoo Jin Jung Rudolph Kaaks Aruna Kamineni Eleanor Kane Chang Hyun Kang Margaret R Karagas Rachel S Kelly Kay-Tee Khaw Christopher Kim Hee Nam Kim Jin Hee Kim Jun Suk Kim Yeul Hong Kim Young Tae Kim Young-Chul Kim Cari M Kitahara Alison P Klein Robert J Klein Manolis Kogevinas Takashi Kohno Laurence N Kolonel Charles Kooperberg Anne Kricker Vittorio Krogh Hideo Kunitoh Robert C Kurtz Sun-Seog Kweon Andrea LaCroix Charles Lawrence Fernando Lecanda Victor Ho Fun Lee Donghui Li Haixin Li Jihua Li Yao-Jen Li Yuqing Li Linda M Liao Mark Liebow Tracy Lightfoot Wei-Yen Lim Chien-Chung Lin Dongxin Lin Sara Lindstrom Martha S Linet Brian K Link Chenwei Liu Jianjun Liu Li Liu Börje Ljungberg Josep Lloreta Simonetta Di Lollo Daru Lu Eiluv Lund Nuria Malats Satu Mannisto Loic Le Marchand Neyssa Marina Giovanna Masala Giuseppe Mastrangelo Keitaro Matsuo Marc Maynadie James McKay Roberta McKean-Cowdin Mads Melbye Beatrice S Melin Dominique S Michaud Tetsuya Mitsudomi Alain Monnereau Rebecca Montalvan Lee E Moore Lotte Maxild Mortensen Alexandra Nieters Kari E North Anne J Novak Ann L Oberg Kenneth Offit In-Jae Oh Sara H Olson Domenico Palli William Pao In Kyu Park Jae Yong Park Kyong Hwa Park Ana Patiño-Garcia Sofia Pavanello Petra H M Peeters Reury-Perng Perng Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Ludmila Prokunina-Olsson Biyun Qian You-Lin Qiao Marco Rais Elio Riboli Jacques Riby Harvey A Risch Cosmeri Rizzato Rebecca Rodabough Eve Roman Morgan Roupret Avima M Ruder Silvia de Sanjose Ghislaine Scelo Alan Schned Fredrick Schumacher Kendra Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Veronica Wendy Setiawan Gianluca Severi Richard K Severson Tait D Shanafelt Hongbing Shen Wei Shen Min-Ho Shin Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesúmaga Alan Dart Loon Sihoe Christine F Skibola Alex Smith Martyn T Smith Melissa C Southey John J Spinelli Anthony Staines Meir Stampfer Marianna C Stern Victoria L Stevens Rachael S Stolzenberg-Solomon Jian Su Wu-Chou Su Malin Sund Jae Sook Sung Sook Whan Sung Wen Tan Wei Tang Adonina Tardón David Thomas Carrie A Thompson Lesley F Tinker Roberto Tirabosco Anne Tjønneland Ruth C Travis Dimitrios Trichopoulos Fang-Yu Tsai Ying-Huang Tsai Margaret Tucker Jenny Turner Claire M Vajdic Roel C H Vermeulen Danylo J Villano Paolo Vineis Jarmo Virtamo Kala Visvanathan Jean Wactawski-Wende Chaoyu Wang Chih-Liang Wang Jiu-Cun Wang Junwen Wang Fusheng Wei Elisabete Weiderpass George J Weiner Stephanie Weinstein Nicolas Wentzensen Emily White Thomas E Witzig Brian M Wolpin Maria Pik Wong Chen Wu Guoping Wu Junjie Wu Tangchun Wu Wei Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Ping Xu Pan-Chyr Yang Tsung-Ying Yang Yuanqing Ye Zhihua Yin Jun Yokota Ho-Il Yoon Chong-Jen Yu Herbert Yu Kai Yu Jian-Min Yuan Andrew Zelenetz Anne Zeleniuch-Jacquotte Xu-Chao Zhang Yawei Zhang Xueying Zhao Zhenhong Zhao Hong Zheng Tongzhang Zheng Wei Zheng Baosen Zhou Meng Zhu Mariagrazia Zucca Simina M Boca James R Cerhan Giovanni M Ferri Patricia Hartge Chao Agnes Hsiung Corrado Magnani Lucia Miligi Lindsay M Morton Karin E Smedby Lauren R Teras Joseph Vijai Sophia S Wang Paul Brennan Neil E Caporaso David J Hunter Peter Kraft Nathaniel Rothman Debra T Silverman Susan L Slager Stephen J Chanock Nilanjan Chatterjee

J Natl Cancer Inst 2015 Dec 12;107(12):djv279. Epub 2015 Oct 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JNS, OP, SIB, QL, CCA, LTA, JDF, MTL, LM, SAS, PRT, KAM, PR, DA, DB, BAB, AB, LBr, WHC, CCC, JSC, JFFJr, NDF, LEBF, MGC, AMG, RNH, NH, WH, PDI, BTJ, CK, CMK, LML, MSL, LEM, LPO, RSSS, WeiT, MT, CWa, SW, NW, KY, PH, LMM, NEC, NR, DTS, SJC, NC); Information Management Services, Silver Spring, MD (WAW, CG); Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MD (MY, ZW, LBu, AH, CLi); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (IDV, KAB, BMB, CoC, MCB, CF, EG, SL, JP, MSt, DJH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (IDV, OA, KAB, CoC, MCB, EG, RSK, SL, JP, HDS, MSt, DTr, DJH, PK); Ontario Health Study, Toronto, Ontario, Canada (MPP); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (HOA, EWe); Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (AA, MF); UCL Cancer Institute, London, UK (MFA, AMF, DH); Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK (MFA, AMF, DH, RT); Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (SJA, JS, YLW, XCZ); Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden (UA, RH, BSM); Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, MO (GAJr, RGIII); Litwin Centre for Cancer Genetics, University of Toronto, Ontario, Canada (ILA, NG, JSW); Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (ILA, SG, NG, JSW); Hematology Unit, Ospedale Oncologico di Riferimento Regionale A. Businco, Cagliari, Italy (EA); Department of Medicin

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http://kooperberg.fhcrc.org/papers/2015sampson.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv27
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http://dx.doi.org/10.1093/jnci/djv279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806328PMC
December 2015

Essential Components of Cancer Education.

Cancer Res 2015 Dec 1;75(24):5202-5. Epub 2015 Dec 1.

Holden Comprehensive Cancer Center, Carver College of Medicine, The University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681646PMC
December 2015

Picking the optimal target for antibody-drug conjugates.

Am Soc Clin Oncol Educ Book 2013

From the Holden Comprehensive Cancer Center and the Department of Internal Medicine, University of Iowa, Iowa City, IA.

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http://meetinglibrary.asco.org//content/17-132
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http://dx.doi.org/10.1200/EdBook_AM.2013.33.e103DOI Listing
November 2015

Genome-Wide Association Study of Event-Free Survival in Diffuse Large B-Cell Lymphoma Treated With Immunochemotherapy.

J Clin Oncol 2015 Nov 12;33(33):3930-7. Epub 2015 Oct 12.

Hervé Ghesquieres, Universite Claude Bernard Lyon 1, Centre Leon Berard; Amelie S. Veron and David G. Cox, L'Institut National de la Santé et de la Recherche Médicale (INSERM) U1052, Cancer Research Center of Lyon, Centre Leon Berard, Lyon; Hervé Ghesquieres and Gilles A. Salles, Faculté de Médecine Lyon-Sud; Gilles A. Salles, Universite Claude Bernard Lyon 1, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite; Fabrice Jardin, Sylvain Mareschal, and Herve Tilly, INSERM U918, Centre Henri Becquerel, Rouen; Thierry Fest, INSERM U917, Université de Rennes 1, Hopital Pontchaillou; Thierry Lamy, Université de Rennes 1, Hopital Pontchaillou, Rennes; Marie C. Bene, Centre Hospitalier Universitaire Nantes, Nantes; Corinne Haioun, Hospital Henri Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP) and University Paris Est, Créteil; Thierry Jo Molina, Universite Paris Descartes, AP-HP, Hôpital Necker, Paris; Noel Milpied, University Hospital and University of Bordeaux, Bordeaux, France; Hervé Ghesquieres, Susan L. Slager, Matthew J. Maurer, Thomas M. Habermann, Anne J. Novak, Stephen M. Ansell, Thomas E. Witzig, Andrew L. Feldman, Ahmet Dogan, Julie M. Cunningham, Curtis L. Olswold, and James R. Cerhan, Mayo Clinic, Rochester, MN; Yan W. Asmann, Mayo Clinic, Jacksonville, FL; and George J. Weiner and Brian K. Link, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1200/JCO.2014.60.2573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879713PMC
November 2015

Building better monoclonal antibody-based therapeutics.

Authors:
George J Weiner

Nat Rev Cancer 2015 Jun;15(6):361-70

Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 5970Z-JPP, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1038/nrc3930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491443PMC
June 2015

Three steps to breaking immune tolerance to lymphoma: a microparticle approach.

Cancer Immunol Res 2015 Apr 27;3(4):389-98. Epub 2015 Jan 27.

Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa. Holden Comprehensive Cancer Center and Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390476PMC
April 2015

Widespread use of complementary and alternative medicine among non-Hodgkin lymphoma survivors.

Leuk Lymphoma 2015 Feb 27;56(2):434-9. Epub 2014 Jun 27.

Department of Emergency Medicine and the Center for Health Equity and Quality Research, University of Florida Jacksonville , Jacksonville, FL , USA.

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http://dx.doi.org/10.3109/10428194.2014.916803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666508PMC
February 2015

Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.

J Immunol 2015 Feb 19;194(3):1011-20. Epub 2014 Dec 19.

Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242; Holden Comprehensive Cancer Center, Carver College of Medicine, University of Iowa, Iowa City, IA 52242;

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http://www.jimmunol.org/content/early/2014/12/19/jimmunol.13
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1303099
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1303099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297687PMC
February 2015

Biodegradable microparticles loaded with doxorubicin and CpG ODN for in situ immunization against cancer.

AAPS J 2015 Jan 18;17(1):184-93. Epub 2014 Oct 18.

Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa, 52242, USA.

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http://dx.doi.org/10.1208/s12248-014-9676-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287287PMC
January 2015

Cancer immunotherapy and breaking immune tolerance: new approaches to an old challenge.

Cancer Res 2015 Jan 18;75(1):5-10. Epub 2014 Dec 18.

Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa. Holden Comprehensive Cancer Center and Department of Internal Medicine, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286422PMC
January 2015

A genome-wide association study of marginal zone lymphoma shows association to the HLA region.

Authors:
Joseph Vijai Zhaoming Wang Sonja I Berndt Christine F Skibola Susan L Slager Silvia de Sanjose Mads Melbye Bengt Glimelius Paige M Bracci Lucia Conde Brenda M Birmann Sophia S Wang Angela R Brooks-Wilson Qing Lan Paul I W de Bakker Roel C H Vermeulen Carol Portlock Stephen M Ansell Brian K Link Jacques Riby Kari E North Jian Gu Henrik Hjalgrim Wendy Cozen Nikolaus Becker Lauren R Teras John J Spinelli Jenny Turner Yawei Zhang Mark P Purdue Graham G Giles Rachel S Kelly Anne Zeleniuch-Jacquotte Maria Grazia Ennas Alain Monnereau Kimberly A Bertrand Demetrius Albanes Tracy Lightfoot Meredith Yeager Charles C Chung Laurie Burdett Amy Hutchinson Charles Lawrence Rebecca Montalvan Liming Liang Jinyan Huang Baoshan Ma Danylo J Villano Ann Maria Marina Corines Tinu Thomas Anne J Novak Ahmet Dogan Mark Liebow Carrie A Thompson Thomas E Witzig Thomas M Habermann George J Weiner Martyn T Smith Elizabeth A Holly Rebecca D Jackson Lesley F Tinker Yuanqing Ye Hans-Olov Adami Karin E Smedby Anneclaire J De Roos Patricia Hartge Lindsay M Morton Richard K Severson Yolanda Benavente Paolo Boffetta Paul Brennan Lenka Foretova Marc Maynadie James McKay Anthony Staines W Ryan Diver Claire M Vajdic Bruce K Armstrong Anne Kricker Tongzhang Zheng Theodore R Holford Gianluca Severi Paolo Vineis Giovanni M Ferri Rosalia Ricco Lucia Miligi Jacqueline Clavel Edward Giovannucci Peter Kraft Jarmo Virtamo Alex Smith Eleanor Kane Eve Roman Brian C H Chiu Joseph F Fraumeni Xifeng Wu James R Cerhan Kenneth Offit Stephen J Chanock Nathaniel Rothman Alexandra Nieters

Nat Commun 2015 Jan 8;6:5751. Epub 2015 Jan 8.

Center For Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg 79108, Germany.

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http://dx.doi.org/10.1038/ncomms6751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287989PMC
January 2015

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.

Authors:
James R Cerhan Sonja I Berndt Joseph Vijai Hervé Ghesquières James McKay Sophia S Wang Zhaoming Wang Meredith Yeager Lucia Conde Paul I W de Bakker Alexandra Nieters David Cox Laurie Burdett Alain Monnereau Christopher R Flowers Anneclaire J De Roos Angela R Brooks-Wilson Qing Lan Gianluca Severi Mads Melbye Jian Gu Rebecca D Jackson Eleanor Kane Lauren R Teras Mark P Purdue Claire M Vajdic John J Spinelli Graham G Giles Demetrius Albanes Rachel S Kelly Mariagrazia Zucca Kimberly A Bertrand Anne Zeleniuch-Jacquotte Charles Lawrence Amy Hutchinson Degui Zhi Thomas M Habermann Brian K Link Anne J Novak Ahmet Dogan Yan W Asmann Mark Liebow Carrie A Thompson Stephen M Ansell Thomas E Witzig George J Weiner Amelie S Veron Diana Zelenika Hervé Tilly Corinne Haioun Thierry Jo Molina Henrik Hjalgrim Bengt Glimelius Hans-Olov Adami Paige M Bracci Jacques Riby Martyn T Smith Elizabeth A Holly Wendy Cozen Patricia Hartge Lindsay M Morton Richard K Severson Lesley F Tinker Kari E North Nikolaus Becker Yolanda Benavente Paolo Boffetta Paul Brennan Lenka Foretova Marc Maynadie Anthony Staines Tracy Lightfoot Simon Crouch Alex Smith Eve Roman W Ryan Diver Kenneth Offit Andrew Zelenetz Robert J Klein Danylo J Villano Tongzhang Zheng Yawei Zhang Theodore R Holford Anne Kricker Jenny Turner Melissa C Southey Jacqueline Clavel Jarmo Virtamo Stephanie Weinstein Elio Riboli Paolo Vineis Rudolph Kaaks Dimitrios Trichopoulos Roel C H Vermeulen Heiner Boeing Anne Tjonneland Emanuele Angelucci Simonetta Di Lollo Marco Rais Brenda M Birmann Francine Laden Edward Giovannucci Peter Kraft Jinyan Huang Baoshan Ma Yuanqing Ye Brian C H Chiu Joshua Sampson Liming Liang Ju-Hyun Park Charles C Chung Dennis D Weisenburger Nilanjan Chatterjee Joseph F Fraumeni Susan L Slager Xifeng Wu Silvia de Sanjose Karin E Smedby Gilles Salles Christine F Skibola Nathaniel Rothman Stephen J Chanock

Nat Genet 2014 Nov 28;46(11):1233-8. Epub 2014 Sep 28.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.3105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213349PMC
November 2014

Utility of routine post-therapy surveillance imaging in diffuse large B-cell lymphoma.

J Clin Oncol 2014 Nov 29;32(31):3506-12. Epub 2014 Sep 29.

Carrie A. Thompson, Matthew J. Maurer, James R. Cerhan, Stephen M. Ansell, David J. Inwards, Patrick B. Johnston, William R. Macon, Ivana N. Micallef, Grzegorz S. Nowakowski, Luis F. Porrata, Thomas E. Witzig, Thomas M. Habermann, Mayo Clinic, Rochester, MN; Herve Ghesquieres, Pierre Biron, Catherine Chassagne-Clément, Thérèse Gargi, Emmanuelle Nicolas-Virelizier, Marie Peix, Catherine Sebban, Centre Leon Berard, University of Lyon, Lyon, France; George J. Weiner and Brian K. Link, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1200/JCO.2014.55.7561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209102PMC
November 2014

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.

Authors:
Christine F Skibola Sonja I Berndt Joseph Vijai Lucia Conde Zhaoming Wang Meredith Yeager Paul I W de Bakker Brenda M Birmann Claire M Vajdic Jia-Nee Foo Paige M Bracci Roel C H Vermeulen Susan L Slager Silvia de Sanjose Sophia S Wang Martha S Linet Gilles Salles Qing Lan Gianluca Severi Henrik Hjalgrim Tracy Lightfoot Mads Melbye Jian Gu Hervé Ghesquières Brian K Link Lindsay M Morton Elizabeth A Holly Alex Smith Lesley F Tinker Lauren R Teras Anne Kricker Nikolaus Becker Mark P Purdue John J Spinelli Yawei Zhang Graham G Giles Paolo Vineis Alain Monnereau Kimberly A Bertrand Demetrius Albanes Anne Zeleniuch-Jacquotte Attilio Gabbas Charles C Chung Laurie Burdett Amy Hutchinson Charles Lawrence Rebecca Montalvan Liming Liang Jinyan Huang Baoshan Ma Jianjun Liu Hans-Olov Adami Bengt Glimelius Yuanqing Ye Grzegorz S Nowakowski Ahmet Dogan Carrie A Thompson Thomas M Habermann Anne J Novak Mark Liebow Thomas E Witzig George J Weiner Maryjean Schenk Patricia Hartge Anneclaire J De Roos Wendy Cozen Degui Zhi Nicholas K Akers Jacques Riby Martyn T Smith Mortimer Lacher Danylo J Villano Ann Maria Eve Roman Eleanor Kane Rebecca D Jackson Kari E North W Ryan Diver Jenny Turner Bruce K Armstrong Yolanda Benavente Paolo Boffetta Paul Brennan Lenka Foretova Marc Maynadie Anthony Staines James McKay Angela R Brooks-Wilson Tongzhang Zheng Theodore R Holford Saioa Chamosa Rudolph Kaaks Rachel S Kelly Bodil Ohlsson Ruth C Travis Elisabete Weiderpass Jacqueline Clavel Edward Giovannucci Peter Kraft Jarmo Virtamo Patrizio Mazza Pierluigi Cocco Maria Grazia Ennas Brian C H Chiu Joseph F Fraumeni Alexandra Nieters Kenneth Offit Xifeng Wu James R Cerhan Karin E Smedby Stephen J Chanock Nathaniel Rothman

Am J Hum Genet 2014 Oct;95(4):462-71

Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ajhg.2014.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185120PMC
October 2014

Complement in monoclonal antibody therapy of cancer.

Immunol Res 2014 Aug;59(1-3):203-10

Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, 52242, USA.

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http://dx.doi.org/10.1007/s12026-014-8542-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381956PMC
August 2014

B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21.

Int Immunol 2014 Jul 4;26(7):383-95. Epub 2014 Feb 4.

Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service Baden-Württemberg - Hessen and Institute of Transfusion Medicine,

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http://dx.doi.org/10.1093/intimm/dxu001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133571PMC
July 2014

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.

Authors:
Sonja I Berndt Christine F Skibola Vijai Joseph Nicola J Camp Alexandra Nieters Zhaoming Wang Wendy Cozen Alain Monnereau Sophia S Wang Rachel S Kelly Qing Lan Lauren R Teras Nilanjan Chatterjee Charles C Chung Meredith Yeager Angela R Brooks-Wilson Patricia Hartge Mark P Purdue Brenda M Birmann Bruce K Armstrong Pierluigi Cocco Yawei Zhang Gianluca Severi Anne Zeleniuch-Jacquotte Charles Lawrence Laurie Burdette Jeffrey Yuenger Amy Hutchinson Kevin B Jacobs Timothy G Call Tait D Shanafelt Anne J Novak Neil E Kay Mark Liebow Alice H Wang Karin E Smedby Hans-Olov Adami Mads Melbye Bengt Glimelius Ellen T Chang Martha Glenn Karen Curtin Lisa A Cannon-Albright Brandt Jones W Ryan Diver Brian K Link George J Weiner Lucia Conde Paige M Bracci Jacques Riby Elizabeth A Holly Martyn T Smith Rebecca D Jackson Lesley F Tinker Yolanda Benavente Nikolaus Becker Paolo Boffetta Paul Brennan Lenka Foretova Marc Maynadie James McKay Anthony Staines Kari G Rabe Sara J Achenbach Celine M Vachon Lynn R Goldin Sara S Strom Mark C Lanasa Logan G Spector Jose F Leis Julie M Cunningham J Brice Weinberg Vicki A Morrison Neil E Caporaso Aaron D Norman Martha S Linet Anneclaire J De Roos Lindsay M Morton Richard K Severson Elio Riboli Paolo Vineis Rudolph Kaaks Dimitrios Trichopoulos Giovanna Masala Elisabete Weiderpass María-Dolores Chirlaque Roel C H Vermeulen Ruth C Travis Graham G Giles Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Jacqueline Clavel Tongzhang Zheng Theodore R Holford Kenneth Offit Andrew Zelenetz Robert J Klein John J Spinelli Kimberly A Bertrand Francine Laden Edward Giovannucci Peter Kraft Anne Kricker Jenny Turner Claire M Vajdic Maria Grazia Ennas Giovanni M Ferri Lucia Miligi Liming Liang Joshua Sampson Simon Crouch Ju-Hyun Park Kari E North Angela Cox John A Snowden Josh Wright Angel Carracedo Carlos Lopez-Otin Silvia Bea Itziar Salaverria David Martin-Garcia Elias Campo Joseph F Fraumeni Silvia de Sanjose Henrik Hjalgrim James R Cerhan Stephen J Chanock Nathaniel Rothman Susan L Slager

Nat Genet 2013 Aug 16;45(8):868-76. Epub 2013 Jun 16.

Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729927PMC
August 2013

Manipulation of cellular redox parameters for improving therapeutic responses in B-cell lymphoma and multiple myeloma.

J Cell Biochem 2012 Feb;113(2):419-25

Free Radical and Radiation Biology Program, Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1002/jcb.23387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374635PMC
February 2012

Cancer immunotherapy comes of age.

J Clin Oncol 2011 Dec 31;29(36):4828-36. Epub 2011 Oct 31.

Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1200/JCO.2011.38.0899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255990PMC
December 2011

Vitamin D insufficiency and prognosis in chronic lymphocytic leukemia.

Blood 2011 Feb 3;117(5):1492-8. Epub 2010 Nov 3.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1182/blood-2010-07-295683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056589PMC
February 2011

Making a better antibody: all is not lost.

Authors:
George J Weiner

Blood 2010 Jun;115(25):5127-8

University of Iowa, IA, USA.

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http://dx.doi.org/10.1182/blood-2010-03-275206DOI Listing
June 2010

Rituximab: mechanism of action.

Authors:
George J Weiner

Semin Hematol 2010 Apr;47(2):115-23

Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242-1002, USA.

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http://dx.doi.org/10.1053/j.seminhematol.2010.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848172PMC
April 2010

CpG oligodeoxynucleotide-based therapy of lymphoid malignancies.

Authors:
George J Weiner

Adv Drug Deliv Rev 2009 Mar 8;61(3):263-7. Epub 2009 Jan 8.

Holden Comprehensive Cancer Center at the University of Iowa, Department of Internal Medicine, Iowa City, 52242, USA.

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http://dx.doi.org/10.1016/j.addr.2008.12.006DOI Listing
March 2009

Short telomeres in B-CLL: the chicken or the egg?

Blood 2008 Jun;111(12):5756; author reply 5756-7

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http://dx.doi.org/10.1182/blood-2008-03-146027DOI Listing
June 2008

CpG oligodeoxynucleotides as immunotherapy in cancer.

Update Cancer Ther 2008 Mar;3(1):27-32

Holden Comprehensive Cancer Center at the University of Iowa, Department of Internal Medicine, 5970Z JPP, University of Iowa, Iowa City, IA 52242, Telephone: +001-319-353-8620, , e-mail:

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http://dx.doi.org/10.1016/j.uct.2007.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390897PMC
March 2008

Monoclonal antibody mechanisms of action in cancer.

Authors:
George J Weiner

Immunol Res 2007 ;39(1-3):271-8

Department of Medicine and The Graduate Program in Immunology, The University of Iowa, Iowa City, IA, USA.

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January 2008

A comparative study of the antigen-specific immune response induced by co-delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles.

J Pharm Sci 2007 Dec;96(12):3283-92

Division of Pharmaceutics, College of Pharmacy, University of Iowa, 115 S. Grand Avenue, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1002/jps.20978DOI Listing
December 2007

Potent antigen-specific immune responses stimulated by codelivery of CpG ODN and antigens in degradable microparticles.

J Immunother 2007 Jul-Aug;30(5):469-78

Division of Pharmaceutics, College of Pharmacy, University of Iowa, 115 S. Grand Avenue, Iowa City, IA, USA.

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https://insights.ovid.com/crossref?an=00002371-200707000-000
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http://dx.doi.org/10.1097/CJI.0b013e31802fd8c6DOI Listing
August 2007

The pattern of clinical breast cancer metastasis correlates with a single nucleotide polymorphism in the C1qA component of complement.

Immunogenetics 2006 Feb 8;58(1):1-8. Epub 2006 Feb 8.

Holden Comprehensive Cancer Center at the University of Iowa, 5216MERF, University of Iowa, Iowa, IA 52242, USA.

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http://link.springer.com/10.1007/s00251-005-0077-y
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http://dx.doi.org/10.1007/s00251-005-0077-yDOI Listing
February 2006

CD16 polymorphisms and NK activation induced by monoclonal antibody-coated target cells.

J Immunol Methods 2005 Sep;304(1-2):88-99

5970 JPP, Holden Comprehensive Cancer Center and Department of Internal Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, United States.

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http://dx.doi.org/10.1016/j.jim.2005.06.018DOI Listing
September 2005

Serum alters the uptake and biologic activity of CpG oligodeoxynucleotides in B cell chronic lymphocytic leukemia.

Oligonucleotides 2005 ;15(1):51-9

The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1089/oli.2005.15.51DOI Listing
July 2005

Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells.

J Leukoc Biol 2005 Mar 6;77(3):378-87. Epub 2004 Dec 6.

Holden Comprehensive Cancer Center, 5970Z JPP, The University of Iowa, Iowa City, IA 52242, USA.

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http://doi.wiley.com/10.1189/jlb.0604373
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http://dx.doi.org/10.1189/jlb.0604373DOI Listing
March 2005

B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides.

Clin Cancer Res 2005 Feb;11(4):1490-9

Holden Comprehensive Cancer Center and Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-1890DOI Listing
February 2005

Phosphorothyoate oligodeoxynucleotides block nonspecific binding of Cy5 conjugates to monocytes.

J Immunol Methods 2005 Feb;297(1-2):259-63

Holden Comprehensive Cancer Center, Department of Internal Medicine, University of Iowa, 5970Z JPP, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.jim.2004.11.023DOI Listing
February 2005

Antibody therapy of lymphoma.

Adv Pharmacol 2004 ;51:229-53

Holden Comprehensive Cancer Center, Department of Internal Medicine, University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1016/S1054-3589(04)51010-4DOI Listing
December 2004

CpG oligodeoxynucleotides enhance FcgammaRI-mediated cross presentation by dendritic cells.

Int Immunol 2004 Aug 10;16(8):1091-8. Epub 2004 Jun 10.

Immunotherapy Laboratory, Department of Immunology, University Medical Center Utrecht, Lundlaan 6, Room KC02-085.2, 3584 EA, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/intimm/dxh110DOI Listing
August 2004

Cancer biology--lost in translation?

Authors:
George J Weiner

Cancer Biol Ther 2004 Jul 5;3(7):688-91. Epub 2004 Jul 5.

Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa 52242-1009, USA.

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http://dx.doi.org/10.4161/cbt.3.7.959DOI Listing
July 2004

Monoclonal antibody therapy of B cell lymphoma.

Expert Opin Biol Ther 2004 Mar;4(3):375-85

Holden Comprehensive Cancer Center and Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://www.tandfonline.com/doi/full/10.1517/14712598.4.3.375
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http://dx.doi.org/10.1517/14712598.4.3.375 DOI Listing
March 2004

CpG DNA and cancer immunotherapy: orchestrating the antitumor immune response.

Curr Opin Oncol 2003 Nov;15(6):440-5

Department of Internal Medicine, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, 52242, USA.

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November 2003

CpG-A and B oligodeoxynucleotides enhance the efficacy of antibody therapy by activating different effector cell populations.

Cancer Res 2003 Sep;63(17):5595-600

Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Center, 3000 DR Rotterdam, The Netherlands.

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September 2003

Immunostimulatory CpG oligodeoxynucleotides and antibody therapy of cancer.

Semin Oncol 2003 Aug;30(4):476-82

Holden Comprehensive Cancer Center, Department of Internal Medicine, Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA.

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August 2003

CpG oligodeoxynucleotides for immune stimulation in cancer immunotherapy.

Curr Opin Investig Drugs 2003 Jun;4(6):686-90

Holden Comprehensive Cancer Center, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.

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June 2003

Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigen.

Cancer Immunol Immunother 2003 May 5;52(5):317-27. Epub 2003 Mar 5.

Department of Internal Medicine and the Barrett Cancer Center, University of Cincinnati, Cincinnati, OH 45267, USA.

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http://dx.doi.org/10.1007/s00262-002-0351-xDOI Listing
May 2003

Synergism between cytosine-guanine oligodeoxynucleotides and monoclonal antibody in the treatment of lymphoma.

Semin Oncol 2002 Feb;29(1S2):93-97

Holden Comprehensive Cancer Center and the Department of Internal Medicine, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1053/sonc.2002.30147DOI Listing
February 2002

Synergism between cytosine-guanine oligodeoxynucleotides and monoclonal antibody in the treatment of lymphoma.

Semin Oncol 2002 Feb;29(1 Suppl 2):93-7

Holden Comprehensive Cancer Center and the Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.

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February 2002